CETP Gene
protein-coding GIFtS: 60
GCID: GC16P056996
|
|
cholesteryl ester transfer protein, plasma
| |
Aliases
for CETP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cholesteryl Ester Transfer Protein, Plasma1 2 | | BPIFF1 2 | | Lipid Transfer Protein I2 3 | | HDLCQ102 5 | | BPI Fold Containing Family F2 | | Cholesteryl Ester Transfer Protein2 |
Export aliases for CETP gene to outside databasesPrevious GC identifers: GC16M047282 GC16P057046 GC16P056730 GC16P056771 GC16P055553 GC16P042865 |
Summaries
for CETP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CETP:
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effectsusceptibility to atherosclerosis. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CETP_HUMAN, P11597Function: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol
Gene Wiki entry for CETP (Cholesterylester transfer protein)
|
Genomic Views
for CETP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CETP gene promoter:
p53 AP-1 MEF-2 ATF-2 MEF-2A c-Rel COMP1 c-Jun Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CETP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CETP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q21 Ensembl cytogenetic band: 16q13 HGNC cytogenetic band: 16q13CETP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P056996: view genomic region
(about GC identifiers)
Start:
|
56,995,762 bp from pter |
End:
|
57,017,757 bp from pter |
Size:
|
21,996 bases |
Orientation:
|
plus strand |
|
Proteins
for CETP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CETP_HUMAN, P11597 (See
protein sequence)Recommended Name: Cholesteryl ester transfer protein precursor Size: 493 amino acids; 54756 Da
Subcellular location: Secreted, extracellular space
3 PDB 3D structures from  and Proteopedia  for CETP:2OBD (3D)
4EWS (3D)
4F2A (3D)
Secondary accessions: Q13987 Q13988 Q53YZ1Alternative splicing: 2 isoforms: P11597-1 P11597-2 Explore the universe of human proteins at neXtProt for CETP: NX_P11597
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P11597
CETP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_000069.2
ENSEMBL proteins: ENSP00000200676 ENSP00000369106 ENSP00000456276 Reactome Protein details: P11597
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CETP for ontologies About GeneDecksing
CETP Antibody Products:
Assay Products for CETP: |
Protein
Domains /
Families
for CETP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CETP for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P11597ProtoNet protein and cluster: P11597 1 Blocks protein family: IPB001124 Lipid-binding serum glycoprotein
UniProtKB/Swiss-Prot: CETP_HUMAN, P11597Similarity: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family |
Function
for CETP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CETP_HUMAN, P11597Function: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol Genatlas biochemistry entry for CETP:cholesteryl ester transfer protein,plasma,with low homology to LBP expressed in and throughout differentiation ofpreadypocyte
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CETP
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CETP (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CETP (NM_000078) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CETP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CETP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CETP |
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
CETP for ontologies About GeneDecksing
|
Pathways & Interactions
for CETP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/7 super-pathways (see all 7) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lipoprotein metabolism | | | 2 | Metabolism | | | 3 | LDL-mediated lipid transport | | | 4 | Selected targets of C/EBPbeta | | | 5 | Selected targets of C/EBPalpha | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 EMD Millipore Pathways for CETP
1  GeneGo (Thomson Reuters) Pathway for CETP
1  BioSystems Pathway for CETP
5/6 
Reactome Pathways for CETP (see all 6)
CETP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CETP
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/7 Interacting proteins for CETP (P115973 ENSP000002006764) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 5/20 biological process terms (GO ID links to tree view) (see all 20): About this table
CETP for ontologies About GeneDecksing
|
Drugs & Compounds
for CETP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CETP for compounds About GeneDecksing
 Compounds for CETP available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| Torcetrapib | Inhibitor of cholesteryl ester transfer protein (CETP) | [262352-17-0] |
10/77 Novoseek chemical compound relationships for CETP gene (see all 77) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| torcetrapib |
95.9 |
220 |
20026784 (6), 19522058 (5), 18808319 (4), 19164467 (4) (see all 91) |
| cholesterol ester |
92.8 |
171 |
15064092 (4), 14608418 (3), 11887180 (2), 8344921 (2) (see all 99) |
| cholesterol |
89.2 |
1527 |
18178167 (9), 8847481 (8), 7857368 (7), 12772435 (7) (see all 99) |
| lipid |
84.2 |
957 |
16905138 (6), 10582542 (6), 7738519 (5), 8908157 (5) (see all 99) |
| phospholipid |
74.8 |
207 |
8071605 (5), 11013306 (4), 8673633 (3), 8908157 (3) (see all 98) |
| atorvastatin |
70.2 |
42 |
17868678 (3), 10634817 (3), 12663600 (3), 16541186 (2) (see all 21) |
| probucol |
68.2 |
71 |
8509722 (6), 1903061 (5), 14642415 (4), 8447724 (4) (see all 21) |
| sele |
67.6 |
3 |
11341749 (1), 11714857 (1), 15076187 (1) |
| niacin |
67.5 |
31 |
18669886 (5), 19825813 (2), 17335774 (2), 16455013 (1) (see all 14) |
| allergens |
66.2 |
45 |
10069888 (3), 15347375 (2), 12002744 (2), 12589356 (2) (see all 33) |
Search CenterWatch for drugs/clinical trials and news about CETP
|
Transcripts
for CETP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CETP gene: NM_000078.2 Unigene Cluster for CETP: Cholesteryl ester transfer protein, plasma Hs.89538 [show with all ESTs]Unigene Representative Sequence: M301854 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000200676(uc002eki.2) ENST00000379780(uc002ekj.2) ENST00000569082
ENST00000566128
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CETP
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CETP (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CETP (NM_000078) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CETP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CETP |
Additional cDNA sequence: AK291586.1 AK297699.1 BC025739.1 BT020064.1 M30185.1 M83573.1 2 DOTS entries: DT.211078 DT.95088624 24/54 AceView cDNA sequences (see all 54): BC025739 AL552260 BQ879525 CR599646 M30185 M83573 BQ068239 BM919861 CR622658 AW196951 BI771118 NM_000078 BI819550 BI041061 BI834490 AA999853 BU753737 BM694301 AW291164 R89105 AI964062 AL546493 AW450046 BV183769
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for CETP About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CETP
|
Expression
for CETP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CETP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See CETP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CETP
SOURCE GeneReport for Unigene cluster: Hs.89538
UniProtKB/Swiss-Prot: CETP_HUMAN, P11597Tissue specificity: Expressed by the liver and secreted in plasma
SABiosciences Expression via Pathway-Focused PCR Array including CETP: | Lipoprotein Signaling & Cholesterol Metabolism in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CETP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CETP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CETP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CETP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CETP |
Orthologs
for CETP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CETP gene from 5/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CETP1 |
cholesteryl ester transfer protein, plasma |
60.78(n)
52.39(a) |
|
415645 NM_001034814.1 NP_001029986.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CETP6 |
-- |
47(a) |
1 ↔ 1 |
GL344281.1(22563-49548) |
zebrafish
(Danio rerio) |
Actinopterygii |
cetp1 |
cholesteryl ester transfer protein, plasma |
53.54(n)
45.3(a) |
|
492488 NM_001007360.1 NP_001007361.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G049706AT3G202706 |
lipid-binding serum glycoprotein-like protein |
16(a)13(a) |
many ↔ manymany ↔ many |
1(1411170-1413627) 3(7067057-7070946) |
rice
(Oryza sativa) |
Liliopsida |
---- |
BPI/LBP family protein At3g20270 precursor, putati...BPI/LBP family protein At3g20270 precursor, putati... |
18(a)16(a) |
many ↔ manymany ↔ many |
9(18568418-18573040) 6(11736121-11740016) |
ENSEMBL Gene Tree for CETP (if available)
TreeFam Gene Tree for CETP (if available) |
Paralogs
for CETP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CETP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
UniProtKB/Swiss-Prot: CETP_HUMAN, P11597Polymorphism: Genetic variations in CETP define the high density lipoprotein cholesterol level quantitative trait locus10 (HDLCQ10) [MIM:143470]
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CETP (56995762 - 57017757 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CETP: --
Human Gene Mutation Database (HGMD): CETP
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CETP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CETP for disorders About GeneDecksing
OMIM gene information: 118470
OMIM disorders: 607322 143470
UniProtKB/Swiss-Prot: CETP_HUMAN, P11597
Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1) [MIM:143470]. Affected individualsshow high levels of alpha-lipoprotein (high density lipoprotein/HDL)
20/107  diseases for CETP (see all 107): About MalaCardscarotid intimal medial thickness atherosclerosis hyperlipoproteinemia type iii basilar artery insufficiency
lipoprotein lipase deficiency benign recurrent intrahepatic cholestasis age related macular degeneration cetp deficiency
patent ductus arteriosus hyperlipoproteinemia aortic aneurysm growth hormone deficiency
abdominal aortic aneurysm peripheral vascular disease familial combined hyperlipidemia hyperalphalipoproteinemia
intrahepatic cholestasis food allergy type 2 diabetes mellitus hyperlipidemia
5 diseases from the University of Copenhagen DISEASES database for CETP:Atherosclerosis Coronary heart disease Diabetes mellitus Familial hyperlipidemia
Myocardial infarction 10/86 Novoseek disease relationships for CETP gene (see all 86) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| cetp deficiency |
97.3 |
366 |
8911072 (6), 15256762 (6), 2215607 (6), 11020466 (6) (see all 99) |
| hyperalphalipoproteinemia |
92.6 |
58 |
11887180 (3), 8333866 (3), 11020466 (3), 8350515 (2) (see all 29) |
| atherosclerosis |
78.1 |
272 |
10195942 (4), 17272756 (4), 16946130 (4), 15256762 (3) (see all 99) |
| hypertriglyceridemia |
74.6 |
34 |
1752964 (3), 8376576 (3), 8977446 (2), 7989603 (2) (see all 21) |
| dyslipidemia |
71.8 |
41 |
15842977 (2), 15529021 (2), 15185777 (1), 17700364 (1) (see all 28) |
| hypercholesterolemia familial |
71.3 |
36 |
7605391 (2), 1634194 (2), 15026427 (2), 7701533 (2) (see all 22) |
| coronary heart disease |
70 |
74 |
15377415 (2), 1975178 (2), 10861897 (2), 16098387 (2) (see all 45) |
| hypoalphalipoproteinemia |
68.8 |
6 |
7712672 (1), 9102177 (1), 7749855 (1), 7583547 (1) |
| allergy food |
65 |
11 |
17489047 (2), 13679821 (1), 17496422 (1), 15672475 (1) (see all 10) |
| hypercholesterolemia |
63.9 |
42 |
10192749 (3), 7749806 (2), 9246022 (2), 12444911 (2) (see all 29) |
Genatlas disease: CETP elevated lipoprotein,high density (HDL) with coronary heart disease (Japanese-American men)
Genetic Association Database (GAD): CETP
Human Genome Epidemiology (HuGE) Navigator: CETP (323 documents)
Export disorders for CETP gene to outside databases
|
Publications
for CETP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CETP gene, integrated from 9 sources (see all 1442):
(articles sorted by number of sources associating them with CETP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Organization of the human cholesteryl ester transfer protein gene. (PubMed id 2334701)1, 2, 3, 9 Agellon L.B....Tall A.R. (1990)
- Cloning and sequencing of human cholesteryl ester transfer protein cDNA. (PubMed id 3600759)1, 2, 3 Drayna D....Lawn R. (1987)
- Increased high-density lipoprotein levels caused by a common cholesteryl-ester transfer protein gene mutation. (PubMed id 2215607)1, 2, 9 Inazu A.... Tall A.R. (1990)
- Haplotype analysis of the CETP gene: not TaqIB, but the closely linked -629C-->A polymorphism and a novel promoter variant are independently associated with CETP concentration. (PubMed id 12499392)1, 4, 9 Klerkx A.H.... Kuivenhoven J.A. (2003)
- A novel cholesteryl ester transfer protein promoter polymorphism (-971G/A) associated with plasma high-density lipoprotein cholesterol levels. Interaction with the TaqIB and -629C/A polymorphisms. (PubMed id 11888509)1, 4, 9 Le Goff W....Thillet J. (2002)
- Human cholesteryl ester transfer protein gene proximal promoter contains dietary cholesterol positive responsive elements and mediates expression in small intestine and periphery while predominant liver and spleen expression is controlled by 5'-distal sequences. Cis-acting sequences mapped in transgenic mice. (PubMed id 8943225)1, 2, 9 Oliveira C.F.O.... Tall A.R. (1996)
- Lack of relationship in long-term type 1 diabetic patients between diabetic nephropathy and polymorphisms in apolipoprotein epsilon, lipoprotein lipase and cholesteryl ester transfer protein. Genetique de la Nephropathie Diabetique Study Group. Donnees Epidemiologiques sur le Syndrome d'Insulino-Resistance Study Group. (PubMed id 11096142)1, 4, 9 Hadjadj S....Marre M. (2000)
- The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia. (PubMed id 16002074)1, 4, 9 Bercovich D....Meiner V. (2006)
- [Relationship between gene polymorphism at CETP locus and hyperlipidemia in the middle-aged and the elder] (PubMed id 15098490)1, 4, 9 Zhao Y....Li Y. (2004)
- Apolipoprotein E and cholesteryl ester transfer protein polymorphisms in normal and preeclamptic pregnancies. (PubMed id 14687732)1, 4, 9 Belo L....Rebelo I. (2004)
|
External Searches for CETP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CETP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CETP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CETP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CETP | Pharmacogenomics, SNPs, Pathways | | SHMPD | http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=CETP | | Wikipedia | http://en.wikipedia.org/wiki/Cholesterylester_transfer_protein |
|
| | |
About This Section
| Patent Information for CETP gene:
Search GeneIP for patents involving CETP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CETP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CETP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CETP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CETP | | | OriGene Protein Over-expression Lysate for CETP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CETP | | OriGene 3'-UTR Clone for CETP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CETP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CETP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CETP | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CETP | | OriGene Custom Protein Services for CETP | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CETP | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CETP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CETP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CETP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CETP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CETP |
| |
 |  |  |  | |
| | | | Tocris compounds for CETP |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CETP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CETP |
|  |  |  | | | | ThermoFisher Antibody for CETP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CETP |
|
|
|
|
