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CETN3 Gene

protein-coding   GIFtS: 58
GCID: GC05M089688

Centrin, EF-Hand Protein, 3

(Previous names: centrin, EF-hand protein, 3 (CDC31 yeast homolog))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Centrin, EF-Hand Protein, 31 2     CDC312 5
CDC31 Yeast Homolog1 2     Centrin, EF-Hand Protein, 3 (CDC31 Yeast Homolog)1
EF-Hand Superfamily Member1 2     Centrin, EF-Hand Protein, 3 (CDC31 Homolog, Yeast)2
CEN32 3     centrin-32

External Ids:    HGNC: 18681   Entrez Gene: 10702   Ensembl: ENSG000001531407   OMIM: 6029075   UniProtKB: O151823   

Export aliases for CETN3 gene to outside databases

Previous GC identifers: GC05M088717 GC05M089980 GC05M089727 GC05M089773 GC05M089725 GC05M084900


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CETN3 Gene:
The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin
protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae.
Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in
centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been
identified in human and other mammalian cells, some of which have been shown to be associated with centrosome
fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which
suggests a similar function to its yeast counterpart. (provided by RefSeq, Jul 2008)

GeneCards Summary for CETN3 Gene:
CETN3 (centrin, EF-hand protein, 3) is a protein-coding gene. Diseases associated with CETN3 include insulin resistance, and hiv-1. GO annotations related to this gene include G-protein beta/gamma-subunit complex binding and calcium ion binding. An important paralog of this gene is EFCAB2.

UniProtKB/Swiss-Prot: CETN3_HUMAN, O15182
Function: Plays a fundamental role in microtubule-organizing center structure and function

Gene Wiki entry for CETN3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NT_034772.7  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CETN3 gene promoter:
         AML1a   POU2F1   POU2F1a   FOXO1a   FOXO1   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCETN3 promoter sequence
   Search Chromatin IP Primers for CETN3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CETN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q14.3   Ensembl cytogenetic band:  5q14.3   HGNC cytogenetic band: 5q14.3

CETN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CETN3 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M089688:  view genomic region     (about GC identifiers)

Start:
89,688,078 bp from pter      End:
89,705,603 bp from pter
Size:
17,526 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CETN3_HUMAN, O15182 (See protein sequence)
Recommended Name: Centrin-3  
Size: 167 amino acids; 19550 Da
Subunit: Monomer (By similarity)
Secondary accessions: Q53YD2 Q9BS23

Explore the universe of human proteins at neXtProt for CETN3: NX_O15182

Explore proteomics data for CETN3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys108, Lys117
  • Modification sites at PhosphoSitePlus

  • See CETN3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_004356.2  
    ENSEMBL proteins: 
     ENSP00000283122   ENSP00000428259   ENSP00000430361   ENSP00000429772   ENSP00000430409  
     ENSP00000429875  

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    CETN3 Antibody Products:

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    CETN3 Assay Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    EFHAND: EF-hand domain containing

    3 InterPro protein domains:
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry O15182

    ProtoNet protein and cluster: O15182

    UniProtKB/Swiss-Prot: CETN3_HUMAN, O15182
    Similarity: Belongs to the centrin family
    Similarity: Contains 4 EF-hand domains


    CETN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CETN3_HUMAN, O15182
    Function: Plays a fundamental role in microtubule-organizing center structure and function

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0008017microtubule binding IEA--
    GO:0031683G-protein beta/gamma-subunit complex binding IEA--
         
    CETN3 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CETN3:
     Increased cell death in breast  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CETN3
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    miRNA
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    miRTarBase miRNAs that target CETN3:
    hsa-mir-1 (MIRT023866)

    Block miRNA regulation of human, mouse, rat CETN3 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CETN3:
    hsa-miR-133a hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidCETN3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CETN3

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CETN3_HUMAN, O15182: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Centrosome of
    interphase and mitotic cells
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol3
    nucleus2
    extracellular1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005813centrosome IDA--
    GO:0005814centriole IEA--
    GO:0032391photoreceptor connecting cilium IEA--
    GO:0045111intermediate filament cytoskeleton IDA--

    CETN3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CETN3
    Interactions:

        Search GeneGlobe Interaction Network for CETN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CETN3 (O151822, 3 ENSP000002831224) via UniProtKB, MINT, STRING, and/or I2D (see all 219)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis IEA--
    GO:0007098centrosome cycle TAS9256449

    CETN3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CETN3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CETN3 gene: 
    NM_004365.2  

    Unigene Cluster for CETN3:

    Centrin, EF-hand protein, 3
    Hs.591767  [show with all ESTs]
    Unigene Representative Sequence: BF218841
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000283122(uc003kjo.3) ENST00000522083 ENST00000522864 ENST00000518458
    ENST00000522565 ENST00000522842
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CETN3 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate CETN3:
    hsa-miR-133a hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmidCETN3 3' UTR sequence
    Inhib. RNA
    Products:
         
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      QuantiTect SYBR Green Assays in human, mouse, rat CETN3
      QuantiFast Probe-based Assays in human, mouse, rat CETN3

    Additional mRNA sequence: 

    BC005383.1 BC093793.1 BC112040.1 BT006688.1 CR450346.1 Y12473.1 

    6 DOTS entries:

    DT.316013  DT.95169524  DT.95355816  DT.100819485  DT.91768596  DT.75122641 

    Selected AceView cDNA sequences (see all 202):

    BU617349 AA992229 BC005383 AA372190 CB156152 BU633663 AA114841 BF589356 
    CA771197 AA417010 BM722364 AW958093 AW961403 AI075035 BG542073 CB160616 
    NM_004365 CF530099 BQ000279 BU740197 AI284054 AA460079 BQ268865 AI371271 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CETN3    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c
    SP1:              -                           
    SP2:                                          
    SP3:                    -                     


    ECgene alternative splicing isoforms for CETN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CETN3 expression in normal human tissues (normalized intensities)      CETN3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGAAAAAAAC
    CETN3 Expression
    About this image


    CETN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Gonad
             XY Germ Cells Testis Cord
     
     Eye (Sensory Organs)
             Retina
    CETN3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CETN3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.591767
        Custom PCR Arrays for CETN3
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CETN3 gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cetn31 , 5 centrin 31, 5 89.02(n)1
    98.8(a)1
      13 (43.68 cM)5
    126261  NM_007684.31  NP_031710.11 
     817832925 
    chicken
    (Gallus gallus)
    Aves CETN31 centrin, EF-hand protein, 3 86.63(n)
    94.01(a)
      427104  XM_424696.3  XP_424696.2 
    lizard
    (Anolis carolinensis)
    Reptilia CETN36
    centrin, EF-hand protein, 3
    90(a)
    1 ↔ 1
    4(104449080-104459299)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.7032 Xenopus laevis transcribed sequence with moderate similarity more 79.61(n)    CA983293.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cetn31 centrin 3 77.31(n)
    83.73(a)
      552931  NM_001020499.1  NP_001018335.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG138986
    --
    29(a)
    many ↔ many
    3L(803427-804051)
    worm
    (Caenorhabditis elegans)
    Secernentea pat-106
    Protein PAT-10 (pat-10) mRNA, complete cds
    27(a)
    many ↔ many
    I(5018770-5020166) WBGene00003934
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CDC31(YOR257W)4
    CDC311
    Calcium-binding component of the spindle pole body more4
    CDC311
    64.58(n)1
    61.81(a)1
      15(811008-811493)4
    8544311, 4  NP_014900.31  NP_014900.14 


    ENSEMBL Gene Tree for CETN3 (if available)
    TreeFam Gene Tree for CETN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CETN3 gene
    EFCAB22  CETN22  CETN12  
    Selected SIMAP similar genes for CETN3 using alignment to 7 protein entries:     CETN3_HUMAN (see all proteins) (see all similar genes):
    CETN2    CETN1    CALM2    CALM1    CALM3    CALML3
    CALML5    TNNC2    EFCAB2    CABP1    CABP5    TNNC1
    CABP2    MYL5    MYL1    ACTN4    MYL6    CALML6

    CETN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CETN3 (see all 276)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs756196831,2
    C,F--89689067(+) GTTTTC/ATATTT 1 -- ds50011Minor allele frequency- A:0.06WA 118
    rs105143261,2
    C,F,H--89689226(+) TTACAA/TTGATA 1 -- ds500118Minor allele frequency- T:0.10NS EA NA WA 1310
    rs1811351411,2
    C--89689439(+) TGTTTC/TAGAAA 1 -- ds50010--------
    rs786130141,2
    C--89689478(+) GAAATA/CCACTC 1 -- ds50010--------
    rs1848294961,2
    --89689542(+) CTAATA/GAAATA 1 -- ut310--------
    rs1893525551,2
    --89689561(+) ATTAAC/TGAAAG 1 -- ut310--------
    rs1481766891,2
    C--89689973(+) TTATTC/TTTTCA 1 -- int10--------
    rs1808764211,2
    --89689992(+) GACTAC/TCATTT 1 -- int10--------
    rs1440738941,2
    --89690133(+) ATAATA/GTGATA 1 -- int10--------
    rs1872316341,2
    --89690141(+) ATAAAC/TATTAC 1 -- int10--------

    HapMap Linkage Disequilibrium report for CETN3 (89688078 - 89705603 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CETN3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv882363CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CETN3
    DNA2.0 Custom Variant and Variant Library Synthesis for CETN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 602907    OMIM disorders: --

    3 diseases for CETN3:    About MalaCards
    insulin resistance    hiv-1    breast cancer


    CETN3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CETN3
    Human Genome Epidemiology (HuGE) Navigator: CETN3 (1 document)

    Export disorders for CETN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CETN3 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with CETN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a new mammalian centrin gene, more closely related to Saccharomyces cerevisiae CDC31 gene. (PubMed id 9256449)1, 2, 3 Middendorp S.... Bornens M. (Proc. Natl. Acad. Sci. U.S.A. 1997)
    2. Centrosome-related genes, genetic variation, and risk of breast cancer. (PubMed id 20508983)1, 4 Olson J.E....Couch F.J. (Breast Cancer Res. Treat. 2011)
    3. Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. (PubMed id 19734900)1, 4 Rung J....Sladek R. (Nat. Genet. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Calcium and magnesium binding to human centrin 3 and interaction with target peptides. (PubMed id 15654740)1, 9 Cox J.A....Craescu C.T. (Biochemistry 2005)
    6. Differential expression and cellular distribution of centrin isoforms during human ciliated cell differentiation in vitro. (PubMed id 10725219)1, 9 Laoukili J....Tournier F. (J. Cell. Sci. 2000)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    10. Expanding the substantial interactome of NEMO using protein microarrays. (PubMed id 20098747)1 Fenner B.J....Prehn J.H. (PLoS ONE 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 1070 HGNC: 1868 AceView: CETN3 Ensembl:ENSG00000153140 euGenes: HUgn1070
    ECgene: CETN3 H-InvDB: CETN3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CETN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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