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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CERS5 Gene

protein-coding   GIFtS: 47
GCID: GC12M050524

ceramide synthase 5

(Previous names: LAG1 longevity assurance homolog 5 (S. cerevisiae), LAG1...)
(Previous symbol: LASS5)
 Explore 2 diseases affiliated with
CERS5 via our new
 Human Malady Compendium 
Biological research products
for CERS5
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Ceramide Synthase 51 2     FLJ253041
LASS51 2 3     MGC454111
Trh41 2     LAG1 Longevity Assurance Homolog 5 (S. Cerevisiae)1
LAG1 Homolog, Ceramide Synthase 51 2     CerS53
LAG1 Longevity Assurance Homolog 52 3     

External Ids:    HGNC: 237491   Entrez Gene: 910122   Ensembl: ENSG000001396247   UniProtKB: Q8N5B73   

Export aliases for CERS5 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CERS5_HUMAN, Q8N5B7
Function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in
cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16)
ceramide) in a fumonisin B1-independent manner (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CERS5
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCERS5 promoter sequence
   Search SABiosciences Chromatin IP Primers for CERS5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CERS5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13.12   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13.12

CERS5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CERS5 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M050524:  view genomic region     (about GC identifiers)

Start:
50,523,575 bp from pter      End:
50,561,288 bp from pter
Size:
37,714 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CERS5_HUMAN, Q8N5B7 (See protein sequence)
Recommended Name: Ceramide synthase 5  
Size: 392 amino acids; 45752 Da
Subcellular location: Nucleus membrane; Multi-pass membrane protein (Potential). Endoplasmic reticulum membrane;
Multi-pass membrane protein (By similarity)

Explore the universe of human proteins at neXtProt for CERS5: NX_Q8N5B7

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8N5B7

  • CERS5 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_671723.1  
    ENSEMBL proteins: 
     ENSP00000448794   ENSP00000369536   ENSP00000447556   ENSP00000447410   ENSP00000325485  
     ENSP00000449311   ENSP00000447266   ENSP00000447029   ENSP00000407896   ENSP00000442918  
     ENSP00000448295   ENSP00000448755   ENSP00000446937   ENSP00000448257   ENSP00000446931  
     ENSP00000450072   ENSP00000389050  
    Reactome Protein details: Q8N5B7
    Human Recombinant Protein Products: 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CERS5

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005783endoplasmic reticulum ----
    GO:0005789endoplasmic reticulum membrane TAS--
    GO:0005792microsome ----
    GO:0016021integral to membrane IEA--


    CERS5 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CERS5 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR016439 Longevity_assurance_LAG1_LAC1
     IPR001356 Homeodomain
     IPR009057 Homeodomain-like
     IPR006634 TLC-dom

    Graphical View of Domain Structure for InterPro Entry Q8N5B7

    ProtoNet protein and cluster: Q8N5B7

    2 Blocks protein families:
    IPB005547 Longevity-assurance protein (LAG1)
    IPB006634 TRAM


    UniProtKB/Swiss-Prot: CERS5_HUMAN, Q8N5B7
    Similarity: Contains 1 homeobox DNA-binding domain
    Similarity: Contains 1 TLC (TRAM/LAG1/CLN8) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CERS5_HUMAN, Q8N5B7
    Function: May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in
    cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl- (C16)
    ceramide) in a fumonisin B1-independent manner (By similarity)

    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate CERS5:
    hsa-miR-3130-5p hsa-miR-647 hsa-miR-1276 hsa-miR-3202 hsa-miR-34b hsa-miR-1284 hsa-miR-335
    SwitchGear 3'UTR luciferase reporter plasmidCERS5 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CERS5

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0043565sequence-specific DNA binding IEA--
    GO:0050291sphingosine N-acyltransferase activity IDA16951403


    CERS5 for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Sphingolipid metabolism
    Sphingolipid metabolism1.00
    Sphingolipid de novo biosynthesis0.46
    2Metabolism
    Metabolism1.00
    Metabolism of lipids and lipoproteins0.34

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    4        Reactome Pathways for CERS5
        Sphingolipid metabolism
    Metabolism
    Metabolism of lipids and lipoproteins
    Sphingolipid de novo biosynthesis



    CERS5 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CERS5

    3 Interacting proteins for CERS5 (Q8N5B73) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EWSR1Q018443I2D: score=1 
    SERTAD1Q9UHV23I2D: score=1 
    WWTR1Q9GZV53I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006665sphingolipid metabolic process TAS--
    GO:0030148sphingolipid biosynthetic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0046513ceramide biosynthetic process IDA16951403


    CERS5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CERS5
    Search CenterWatch for drugs/clinical trials and news about CERS5 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CERS5 gene: 
    NM_147190.2  

    Unigene Cluster for CERS5:

    Ceramide synthase 5
    Hs.270525  [show with all ESTs]
    Unigene Representative Sequence: BC033558
    18/28 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 28):
    ENST00000551697 ENST00000380189(uc001rwf.4) ENST00000551005(uc001rwc.3)
    ENST00000547787(uc001rwd.4 uc001rwe.4) ENST00000317551(uc010smq.1)
    ENST00000546406 ENST00000550919 ENST00000553122 ENST00000550079 ENST00000551757
    ENST00000548942 ENST00000550547 ENST00000438450 ENST00000547138 ENST00000546676
    ENST00000542320 ENST00000547800 ENST00000549089

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    SwitchGear 3'UTR luciferase reporter plasmidCERS5 3' UTR sequence
    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CERS5
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    Additional cDNA sequence: 

    AK026014.1 AK027087.1 AK055740.1 AK058033.1 AK294521.1 AK298924.1 AK300937.1 AK308930.1 
    BC014637.1 BC032565.1 BC033558.1 U15426.1 

    20 DOTS entries:

    DT.100805869  DT.100025003  DT.70104773  DT.97816602  DT.444776  DT.92436993  DT.428724  DT.95098210 
    DT.91675317  DT.121183231  DT.86838936  DT.97796847  DT.97845422  DT.100805870  DT.121183195  DT.75197877 
    DT.91952126  DT.92436989  DT.92436992  DT.121183191 

    24/243 AceView cDNA sequences (see all 243):

    BI870365 Z42984 CA439004 BQ721513 AA489165 BX118634 AI151163 BM665614 
    BM711803 AA236771 CB137489 BM798014 AA417054 AA053726 AA056080 AA018127 
    CB216425 BC033558 CR602245 BX113560 BC014637 AK026014 CF619429 AK055740 

    GeneLoc Exon Structure

    5/21 Alternative Splicing Database (ASD) splice patterns (SP) for CERS5 (see all 21)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c · 9d · 9e · 9f ^ 10a · 10b ^ 11 ^ 12a · 12b ·
    SP1:                                      -     -     -     -     -     -     -     -           -     -                                                         
    SP2:                                                                                                                                                            
    SP3:                                      -     -     -     -           -     -     -           -     -                                                         
    SP4:                                      -     -     -     -     -     -     -     -           -     -                                               -     -   
    SP5:                                      -     -     -     -     -     -     -     -           -     -                             -     -                     

    ExUns: 12c · 12d ^ 13a · 13b ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b · 16c · 16d ^ 17 ^ 18 ^ 19a · 19b · 19c
    SP1:                                      -     -     -                 -     -     -                     
    SP2:                                      -     -     -                       -     -                     
    SP3:                                                                                                      
    SP4:  -     -                                                                                             
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for CERS5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CERS5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGAAGAGGGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CERS5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CERS5

    SOURCE GeneReport for Unigene cluster: Hs.270525
        SABiosciences Custom PCR Arrays for CERS5
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CERS5 gene from 8/25 species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves CERS51 ceramide synthase 5 74.89(n)
    78.15(a)
      426879  XM_424486.2  XP_424486.2 
    lizard
    (Anolis carolinensis)
    Reptilia CERS56
    --
    73(a)
    1 ↔ 1
    2(91595611-91620288)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.173942 Xenopus laevis TRH4 (TRH4) mRNA, complete cds 74.5(n)    AF483906.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BC053143.12   -- 76.89(n)   323020  BC053143.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta schlank1 CG3576-PA 53.43(n)
    46(a)
      50392  NM_144269.3  NP_652526.1 
    worm
    (Caenorhabditis elegans)
    Secernentea hyl-11 Protein HYL-1 47.1(n)
    36.39(a)
      177660  NM_069058.5  NP_501459.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons LOH21 LAG1 longevity assurance homolog 2 43.48(n)
    32.27(a)
      821460  NM_112813.1  NP_188557.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g02640001 hypothetical protein 47.35(n)
    35.98(a)
      4332339  NM_001056174.1  NP_001049639.1 


    ENSEMBL Gene Tree for CERS5 (if available)
    TreeFam Gene Tree for CERS5 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CERS5 gene
    CERS22  CERS42  CERS12  CERS62  CERS32  
    13 SIMAP similar genes for CERS5 using alignment to 15 protein entries:     CERS5_HUMAN (see all proteins):
    LASS5    SNX1    CLUL1    TMEM14B    CERS6    MPP4
    NSRP1    CERS2    CERS4    C10orf137    CERS3    CERS1
    LASS1

    CERS5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/685 NCBI SNPs in CERS5 are shown (see all 685    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1850923661,2
    --50523128(+) AGCTAC/TACCAA 1 -- int10--------
    rs57981281,2
    C--50523285(+) tttttT/-ttttt 1 -- int12Minor allele frequency- -:0.25NA 4
    rs2004452291,2
    --50523475(+) AAAAA-/TTTTTGG 1 -- int10--------
    rs795377431,2
    F,--50523496(+) CTTCTG/CAATCA 1 -- int11Minor allele frequency- C:0.05WA 118
    rs15548451,2
    C,F,O,A,H,--50523504(+) TCAGAC/TCTGGA 1 -- int121Minor allele frequency- T:0.30MN NA NS EA WA 1518
    rs123024651,2
    C,F,H,--50523529(+) GCTTAT/CGGATT 1 -- int111Minor allele frequency- C:0.03NS EA NA WA 1310
    rs1904138961,2
    --50523545(+) AACTGC/TGGATA 1 -- int10--------
    rs123224081,2
    C,H--50523577(+) CAGTAG/AAGGTG 1 -- int14Minor allele frequency- A:0.00NS EA 416
    rs105381421,2
    C,--50523602(+) TAATC-/ACAA  
            
    ACAAA
    1 -- ut312Minor allele frequency- ACAA:0.25NA CSA 4
    rs1458637781,2
    --50523647(+) TGGCT-/GGGGGG
            
    GTTGC
    1 -- ut310--------

    HapMap Linkage Disequilibrium report for CERS5 (50523575 - 50561288 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CERS5: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CERS5 for disorders           About GeneDecksing

    2 diseases for CERS5:    About MalaCards
    hypoxia    malaria


    Export disorders for CERS5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CERS5 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with CERS5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor. (PubMed id 16100120)1, 9 Lahiri S. and Futerman A.H. (2005)
    3. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    4. Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells. (PubMed id 20406683)1 Mesicek J....Kolesnick R. (2010)
    5. Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells. (PubMed id 18676372)1 Jin J....Hsu Y.T. (2008)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)
    7. Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity. (PubMed id 16951403)1 Spassieva S....Obeid L.M. (2006)
    8. Protein kinase C-induced activation of a ceramide/protein phosphatase 1 pathway leading to dephosphorylation of p38 MAPK. (PubMed id 17030510)1 Kitatani K....Hannun Y.A. (2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants. (PubMed id 16550190)9 van Hall T....Offringa R. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 91012 HGNC: 23749 AceView: LASS5 Ensembl:ENSG00000139624 euGenes: HUgn91012
    ECgene: CERS5 H-InvDB: CERS5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CERS5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CERS5 gene:
    Search GeneIP for patents involving CERS5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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