Aliases for CERS5 Gene
Aliases for CERS5 Gene
External Ids for CERS5 Gene
- HGNC: 23749
- Entrez Gene: 91012
- Ensembl: ENSG00000139624
- OMIM: 615335
- UniProtKB: Q8N5B7
Previous HGNC Symbols for CERS5 Gene
- LASS5
Previous GeneCards Identifiers for CERS5 Gene
- GC12M050524
Summaries for CERS5 Gene
-
This gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for CERS5 Gene
CERS5 (Ceramide Synthase 5) is a Protein Coding gene. Among its related pathways are Sphingolipid metabolism and Sphingolipid signaling pathway. GO annotations related to this gene include sphingosine N-acyltransferase activity. An important paralog of this gene is CERS6.
UniProtKB/Swiss-Prot for CERS5 Gene
-
Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity).
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CERS5 Gene
Genomics for CERS5 Gene
Regulatory Elements for CERS5 Gene
Enhancers for CERS5 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CERS5 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CERS5 Gene
- Chromosome:
- 12
- Start:
- 50,129,306 bp from pter
- End:
- 50,167,533 bp from pter
- Size:
- 38,228 bases
- Orientation:
- Minus strand
Genomic View for CERS5 Gene
Genes around CERS5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q13.12 by Ensembl
- 12q13.12 by Entrez Gene
- 12q13.12 by HGNC
CERS5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CERS5 Gene
Proteins for CERS5 Gene
-
Protein details for CERS5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N5B7-CERS5_HUMAN
- Recommended name:
- Ceramide synthase 5
- Protein Accession:
- Q8N5B7
- B4DV54
Protein attributes for CERS5 Gene
- Size:
- 392 amino acids
- Molecular mass:
- 45752 Da
- Quaternary structure:
- No Data Available
Protein Expression for CERS5 Gene
Post-translational modifications for CERS5 Gene
Other Protein References for CERS5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for CERS5
- Novus Biologicals Antibodies for CERS5
-
Abcam antibodies for CERS5
- Invitrogen Antibodies for CERS5
- antibodies-online Antibodies for CERS5: See all 65
- GeneTex CERS5 antibody for CERS5
-
Custom Antibody ServicesProSci Antibodies for CERS5
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for CERS5
- Origene Custom Protein Services for CERS5
- Novus Biologicals proteins for CERS5
- Search GeneTex for Proteins for CERS5
-
Abcam proteins for CERS5
Assay Products
No data available for DME Specific Peptides for CERS5 Gene
Domains & Families for CERS5 Gene
Gene Families for CERS5 Gene
Protein Domains for CERS5 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CERS5 Gene
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CERS5 Gene
Function for CERS5 Gene
Molecular function for CERS5 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Acyl-CoA + sphingosine = CoA + N-acylsphingosine.
- UniProtKB/Swiss-Prot Function:
- Dihydroceramide synthase. Catalyzes the acylation of sphingosine to form dihydroceramide, with high selectivity toward palmitoyl-CoA as acyl donor compared to stearoyl-CoA. Inhibited by fumonisin B1 (By similarity).
Enzyme Numbers (IUBMB) for CERS5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0050291 | sphingosine N-acyltransferase activity | TAS | -- |
Phenotypes for CERS5 Gene
- MGI mutant phenotypes for CERS5:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CERS5:
Animal Models for CERS5 Gene
- MGI Knock Outs for CERS5:
-
- Cers5 tm2b(KOMP)Mbp
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CERS5
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CERS5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS5 gene
- Search ViGene Biosciences for CERS5
CRISPR Products
-
OriGene CRISPR knockouts for CERS5
-
Santa Cruz Biotechnology (SCBT) CRISPR for CERS5
- GenScript: Design CRISPR guide RNA sequences for CERS5
miRNA for CERS5 Gene
- miRTarBase miRNAs that target CERS5
miRNA Products
- Search ViGene Biosciences for CERS5
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CERS5
- Browse OriGene Inhibitory RNA Products For CERS5
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS5 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CERS5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CERS5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CERS5
-
ViGene Biosciences adenoviral particle packaged cDNA for CERS5 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CERS5 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS5 gene
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CERS5 Gene
Localization for CERS5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CERS5 Gene
- Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| nucleus | 4 |
| plasma membrane | 3 |
| lysosome | 2 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IBA | -- |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for CERS5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Sphingolipid metabolism | ||
| 2 | Metabolism |
.37
|
|
| 3 | Sphingolipid signaling pathway | ||
Pathways by source for CERS5 Gene
1 BioSystems pathway for CERS5 Gene
4 Reactome pathways for CERS5 Gene
3 KEGG pathways for CERS5 Gene
UniProtKB/Swiss-Prot Q8N5B7-CERS5_HUMAN
- Pathway: Lipid metabolism; sphingolipid metabolism.
Interacting Proteins for CERS5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0006665 | sphingolipid metabolic process | IEA | -- |
| GO:0030148 | sphingolipid biosynthetic process | TAS | -- |
| GO:0046513 | ceramide biosynthetic process | IDA | 16951403 |
No data available for SIGNOR curated interactions for CERS5 Gene
Drugs & Compounds for CERS5 Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| 3-O-Sulfogalactosylceramide (d18:1/12:0) |
|
852100-88-0 |
|
|||
| 3-O-Sulfogalactosylceramide (d18:1/14:0) |
|
|
||||
| 3-O-Sulfogalactosylceramide (d18:1/16:0) |
|
862509-48-6 |
|
|||
| 3-O-Sulfogalactosylceramide (d18:1/18:0) |
|
244215-65-4 |
|
|||
| 3-O-Sulfogalactosylceramide (d18:1/18:1(9Z)) |
|
|
Transcripts for CERS5 Gene
mRNA/cDNA for CERS5 Gene
- (14) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (243) Selected AceView cDNA sequences:
- (28) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CERS5
-
Santa Cruz Biotechnology (SCBT) CRISPR for CERS5
- GenScript: Design CRISPR guide RNA sequences for CERS5
miRNA Products
- Search ViGene Biosciences for CERS5
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CERS5
- Browse OriGene Inhibitory RNA Products For CERS5
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS5 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CERS5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CERS5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e | · | 9f | ^ | 10a | · | 10b | ^ | 11 | ^ | 12a | · | 12b | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP13: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP14: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP15: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP16: | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP17: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP18: | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP19: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP20: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP21: |
| ExUns: | 12c | · | 12d | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | · | 16d | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | · | 19c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||||||
| SP8: | |||||||||||||||||||||||||||||||||
| SP9: | |||||||||||||||||||||||||||||||||
| SP10: | |||||||||||||||||||||||||||||||||
| SP11: | |||||||||||||||||||||||||||||||||
| SP12: | |||||||||||||||||||||||||||||||||
| SP13: | |||||||||||||||||||||||||||||||||
| SP14: | |||||||||||||||||||||||||||||||||
| SP15: | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP16: | |||||||||||||||||||||||||||||||||
| SP17: | |||||||||||||||||||||||||||||||||
| SP18: | |||||||||||||||||||||||||||||||||
| SP19: | |||||||||||||||||||||||||||||||||
| SP20: | - | - | - | ||||||||||||||||||||||||||||||
| SP21: | - |
Expression for CERS5 Gene
This gene is overexpressed in Bone marrow mesenchymal stem cell (55.8) and Heart (8.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CERS5 Gene
NURSA nuclear receptor signaling pathways regulating expression of CERS5 Gene:
CERS5SOURCE GeneReport for Unigene cluster for CERS5 Gene:
Hs.270525Evidence on tissue expression from TISSUES for CERS5 Gene
- Intestine(4.2)
- Eye(4.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for CERS5
-
OriGene qPCR primer pairs for CERS5
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CERS5 Gene
Orthologs for CERS5 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LASS5 34 |
|
||
| CERS5 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | CERS5 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CERS5 34 |
|
||
| LASS5 35 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Cers5 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cers5 34 |
|
||
| chicken (Gallus gallus) |
Aves | CERS5 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | CERS5 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cers5 34 |
|
||
| Str.2155 34 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.17394 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cers5 34 35 |
|
||
| -- 34 |
|
||||
| rainbow trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3018 34 |
|
||
| fruit fly (Drosophila melanogaster) |
Insecta | schlank 34 35 |
|
||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP001761 34 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | hyl-1 34 35 |
|
||
| hyl-2 35 |
|
ManyToMany | |||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | LOH2 34 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os03g0264000 34 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.9504 35 |
|
OneToMany |
- Species where no ortholog for CERS5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CERS5 Gene
(14) SIMAP similar genes for CERS5 Gene using alignment to 13 proteins:
Variants for CERS5 Gene
| SNP ID | Clin | Chr 12 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000002868 | -- | 50,158,422(+) | TTTTC(C/G/T)TGTCC | intron-variant | |
| rs1000046868 | -- | 50,135,126(+) | AGAGA(A/G)GAGAG | intron-variant, downstream-variant-500B | |
| rs1000181253 | -- | 50,141,892(+) | CTGAG(A/T)TTCCA | intron-variant | |
| rs1000202158 | -- | 50,154,684(+) | TATTA(-/T)TTTTT | intron-variant | |
| rs1000286327 | -- | 50,163,002(+) | CAAGC(A/C)ATCTT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2672487 | CNV | deletion | 23128226 |
| esv2674859 | CNV | deletion | 23128226 |
| esv3629472 | CNV | loss | 21293372 |
| esv3629473 | CNV | loss | 21293372 |
| nsv1144622 | CNV | deletion | 24896259 |
| nsv558840 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
57.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.14;
23.10% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CERS5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CERS5
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CERS5 Gene
Disorders for CERS5 Gene
Relevant External Links for CERS5
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CERS5
No disorders were found for CERS5 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CERS5 Gene
Publications for CERS5 Gene
- LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor. (PMID: 16100120) Lahiri S. … Futerman A.H. (J. Biol. Chem. 2005) 3 22 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. (PMID: 26887952) Sassa T. … Kihara A. (J. Biol. Chem. 2016) 3 64
- Linking the ceramide synthases (CerSs) 4 and 5 with apoptosis, endometrial and colon cancers. (PMID: 25779024) Mojakgomo R. … Dlamini Z. (Exp. Mol. Pathol. 2015) 3 64
Products for CERS5 Gene
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- Novus Biologicals Antibodies for CERS5
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- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CERS5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer