Aliases for CERS4 Gene
Aliases for CERS4 Gene
External Ids for CERS4 Gene
- HGNC: 23747
- Entrez Gene: 79603
- Ensembl: ENSG00000090661
- OMIM: 615334
- UniProtKB: Q9HA82
Previous HGNC Symbols for CERS4 Gene
- LASS4
Previous GeneCards Identifiers for CERS4 Gene
- GC19P008276
Summaries for CERS4 Gene
GeneCards Summary for CERS4 Gene
CERS4 (Ceramide Synthase 4) is a Protein Coding gene. Among its related pathways are Sphingolipid metabolism and Sphingolipid signaling pathway. GO annotations related to this gene include sphingosine N-acyltransferase activity. An important paralog of this gene is CERS2.
UniProtKB/Swiss-Prot for CERS4 Gene
-
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity).
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CERS4 Gene
Genomics for CERS4 Gene
Regulatory Elements for CERS4 Gene
Enhancers for CERS4 Gene
| GeneHancer Identifier | Enhancer Score | Enhancer Sources | Gene-Enhancer Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Gene Targets for Enhancer |
|---|---|---|---|---|---|---|---|---|
| GH19G008207 | 1.3 | ENCODE dbSUPER | 48.2 | +2.5 | 2473 | 3.6 | HDGF ATF1 WRNIP1 ARID4B SIN3A DMAP1 ZNF48 YY1 TCF12 SLC30A9 | CERS4 ENSG00000271717 |
| GH19G008205 | 0.5 | ENCODE | 47.2 | -0.2 | -184 | 1.3 | ZNF121 POU5F1 ZMYM3 REST | CERS4 LOC100422633 |
| GH19G008239 | 1.6 | Ensembl ENCODE dbSUPER | 13.3 | +33.7 | 33689 | 2.0 | HDGF PKNOX1 FOXA2 MLX ARNT AGO1 SIN3A ARID4B ZNF2 YY1 | HNRNPM ELAVL1 ZNF558 XAB2 ZNF414 CERS4 ENSG00000269300 ENSG00000271717 GC19P008268 |
| GH19G008213 | 0.7 | dbSUPER | 28 | +8.4 | 8370 | 2.7 | FOXA2 ZMYM3 NFXL1 RAD21 BCL11B ZNF121 ZFHX2 ZNF366 ZNF652 EGR2 | CERS4 ENSG00000271717 |
| GH19G008202 | 0.9 | ENCODE | 19.3 | -2.7 | -2656 | 2.9 | PKNOX1 ZNF143 ZNF207 MXD4 REST TBX21 KAT8 ZNF592 MIER3 SMARCA4 | CERS4 LOC100422633 |
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around CERS4 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for CERS4 Gene
- Chromosome:
- 19
- Start:
- 8,206,736 bp from pter
- End:
- 8,262,421 bp from pter
- Size:
- 55,686 bases
- Orientation:
- Plus strand
Genomic View for CERS4 Gene
Genes around CERS4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.2 by Ensembl
- 19p13.2 by Entrez Gene
- 19p13.2 by HGNC
CERS4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CERS4 Gene
Proteins for CERS4 Gene
-
Protein details for CERS4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HA82-CERS4_HUMAN
- Recommended name:
- Ceramide synthase 4
- Protein Accession:
- Q9HA82
- D6W665
Protein attributes for CERS4 Gene
- Size:
- 394 amino acids
- Molecular mass:
- 46399 Da
- Quaternary structure:
- No Data Available
Protein Expression for CERS4 Gene
Post-translational modifications for CERS4 Gene
Other Protein References for CERS4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CERS4
- Novus Biologicals Antibodies for CERS4
-
Abcam antibodies for CERS4
- Invitrogen Antibodies for CERS4
- antibodies-online Antibodies for CERS4: See all 46
- Search GeneTex for Antibodies for CERS4
-
Santa Cruz Biotechnology (SCBT) Antibodies for CERS4
Protein Products
-
OriGene Purified Proteins for CERS4
- Search Origene for MassSpec and Protein Over-expression Lysates for CERS4
- Origene Custom Protein Services for CERS4
- antibodies-online Proteins for CERS4: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CERS4
-
Abcam proteins for CERS4
Assay Products
No data available for DME Specific Peptides for CERS4 Gene
Domains & Families for CERS4 Gene
Gene Families for CERS4 Gene
Protein Domains for CERS4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CERS4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for CERS4 Gene
Function for CERS4 Gene
Molecular function for CERS4 Gene
- UniProtKB/Swiss-Prot Function:
- May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner (By similarity).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0050291 | sphingosine N-acyltransferase activity | TAS | -- |
Phenotypes for CERS4 Gene
- MGI mutant phenotypes for CERS4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CERS4:
Animal Models for CERS4 Gene
- MGI Knock Outs for CERS4:
-
- Cers4 tm1.1Kwi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CERS4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CERS4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS4 gene
- Search ViGene Biosciences for CERS4
CRISPR Products
-
OriGene CRISPR knockouts for CERS4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CERS4
- GenScript: Design CRISPR guide RNA sequences for CERS4
miRNA for CERS4 Gene
- miRTarBase miRNAs that target CERS4
-
- hsa-mir-9-5p (MIRT021339)
- hsa-mir-3692-3p (MIRT494876)
- hsa-mir-192-3p (MIRT494877)
- hsa-mir-502-5p (MIRT494878)
- hsa-mir-5189-3p (MIRT494879)
- hsa-mir-1915-5p (MIRT494880)
- hsa-mir-6841-3p (MIRT494881)
- hsa-mir-500b-5p (MIRT494882)
- hsa-mir-362-5p (MIRT494883)
- hsa-mir-129-5p (MIRT617209)
- hsa-mir-8055 (MIRT617210)
- hsa-mir-4753-3p (MIRT617211)
- hsa-mir-4313 (MIRT617212)
- hsa-mir-130b-5p (MIRT617213)
- hsa-mir-4708-5p (MIRT642528)
- hsa-mir-6088 (MIRT642529)
- hsa-mir-4770 (MIRT642530)
- hsa-mir-143-3p (MIRT642531)
- hsa-mir-498 (MIRT642532)
- hsa-mir-4279 (MIRT642533)
- hsa-mir-3118 (MIRT642534)
- hsa-mir-134-5p (MIRT642535)
- hsa-mir-1976 (MIRT642536)
- hsa-mir-3653-5p (MIRT642537)
- hsa-mir-6727-3p (MIRT642538)
- hsa-mir-4722-3p (MIRT642539)
- hsa-mir-4726-3p (MIRT642540)
- hsa-mir-6764-5p (MIRT642541)
- hsa-mir-1915-3p (MIRT642542)
- hsa-mir-6840-3p (MIRT642543)
- hsa-mir-1273f (MIRT661273)
- hsa-mir-5089-5p (MIRT678977)
- hsa-mir-4666a-5p (MIRT678978)
- hsa-mir-6778-3p (MIRT678979)
- hsa-mir-6506-5p (MIRT678980)
- hsa-mir-619-5p (MIRT678981)
- hsa-mir-6747-3p (MIRT678982)
- hsa-mir-4740-3p (MIRT678983)
- hsa-mir-6879-3p (MIRT708415)
- hsa-mir-153-5p (MIRT708416)
- hsa-mir-4704-3p (MIRT708417)
- hsa-mir-500b-3p (MIRT708418)
- hsa-mir-660-5p (MIRT708419)
- hsa-mir-335-3p (MIRT712693)
- hsa-mir-630 (MIRT712694)
- hsa-mir-4999-5p (MIRT712695)
- hsa-mir-4718 (MIRT712696)
- hsa-mir-1537-5p (MIRT712697)
- hsa-mir-1909-5p (MIRT712698)
- hsa-mir-4742-3p (MIRT712699)
- hsa-mir-4501 (MIRT712700)
- hsa-mir-512-3p (MIRT712701)
miRNA Products
- Search ViGene Biosciences for CERS4
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CERS4
- Browse OriGene Inhibitory RNA Products For CERS4
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS4 gene
Clone Products
-
OriGene ORF clones in human for CERS4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CERS4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CERS4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for CERS4
-
ViGene Biosciences adenoviral particle packaged cDNA for CERS4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CERS4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS4 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CERS4 Gene
Localization for CERS4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CERS4 Gene
- Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| plasma membrane | 4 |
| nucleus | 3 |
| golgi apparatus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005783 | endoplasmic reticulum | IBA,IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for CERS4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Sphingolipid metabolism | ||
| 2 | Metabolism |
.37
|
|
| 3 | Sphingolipid signaling pathway | ||
Pathways by source for CERS4 Gene
1 BioSystems pathway for CERS4 Gene
4 Reactome pathways for CERS4 Gene
3 KEGG pathways for CERS4 Gene
Interacting Proteins for CERS4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006629 | lipid metabolic process | IEA | -- |
| GO:0030148 | sphingolipid biosynthetic process | TAS | -- |
| GO:0046513 | ceramide biosynthetic process | IBA | -- |
No data available for SIGNOR curated interactions for CERS4 Gene
Transcripts for CERS4 Gene
mRNA/cDNA for CERS4 Gene
- (10) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (184) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
-
OriGene CRISPR knockouts for CERS4
-
Santa Cruz Biotechnology (SCBT) CRISPR for CERS4
- GenScript: Design CRISPR guide RNA sequences for CERS4
miRNA Products
- Search ViGene Biosciences for CERS4
Inhibitory RNA Products
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for CERS4
- Browse OriGene Inhibitory RNA Products For CERS4
-
ViGene Biosciences ready-to-package AAV shRNAs for CERS4 gene
Clone Products
-
OriGene ORF clones in human for CERS4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CERS4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CERS4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | - |
Expression for CERS4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Frontal cortex (14.6), Retina (14.3), and Liver (12.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CERS4 Gene
NURSA nuclear receptor signaling pathways regulating expression of CERS4 Gene:
CERS4SOURCE GeneReport for Unigene cluster for CERS4 Gene:
Hs.515111Evidence on tissue expression from TISSUES for CERS4 Gene
- Liver(4.2)
- Lung(4.2)
Primer Products
-
OriGene qPCR primer pairs and template standards for CERS4
-
OriGene qPCR primer pairs for CERS4
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CERS4 Gene
Orthologs for CERS4 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LASS4 34 |
|
||
| CERS4 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | CERS4 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | CERS4 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cers4 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Cers4 34 16 35 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CERS4 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| chicken (Gallus gallus) |
Aves | LOC420050 34 |
|
||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cers4 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC100330155 34 |
|
||
| CERS4 (1 of 2) 35 |
|
OneToMany | |||
| cers4a 35 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | schlank 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | hyl-1 35 |
|
ManyToMany | |
| hyl-2 35 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | LAG1 37 |
|
|
|
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany | |||
| -- 35 |
|
ManyToMany |
- Species where no ortholog for CERS4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for CERS4 Gene
(6) SIMAP similar genes for CERS4 Gene using alignment to 8 proteins:
Variants for CERS4 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000032576 | -- | 8,260,170(+) | GCTGA(C/T)TGGGG | intron-variant | |
| rs1000034726 | -- | 8,220,967(+) | TAGGC(A/G)CCCGC | intron-variant | |
| rs1000148440 | -- | 8,248,310(+) | GGATG(A/G)ATGGA | intron-variant | |
| rs1000175585 | -- | 8,260,837(+) | TCCCA(A/G)CTACT | intron-variant | |
| rs1000196572 | -- | 8,233,872(+) | AAAAT(C/T)AGCTG | intron-variant |
Residual Variation Intolerance Score:
40.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
11.38;
92.72% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for CERS4 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CERS4
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CERS4 Gene
Disorders for CERS4 Gene
Relevant External Links for CERS4
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- CERS4
No disorders were found for CERS4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CERS4 Gene
Publications for CERS4 Gene
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Enzyme Activities of the Ceramide Synthases CERS2-6 Are Regulated by Phosphorylation in the C-terminal Region. (PMID: 26887952) Sassa T. … Kihara A. (J. Biol. Chem. 2016) 3 64
- Genetic loci associated with circulating levels of very long-chain saturated fatty acids. (PMID: 25378659) Lemaitre R.N. … Friedlander Y. (J. Lipid Res. 2015) 3 64
- Linking the ceramide synthases (CerSs) 4 and 5 with apoptosis, endometrial and colon cancers. (PMID: 25779024) Mojakgomo R. … Dlamini Z. (Exp. Mol. Pathol. 2015) 3 64
Products for CERS4 Gene
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- CloneReady with Over 120,000 Genes
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- Abcam antibodies for CERS4
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- antibodies-online Antibodies for CERS4: See all 46
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- antibodies-online Proteins for CERS4: See all 5
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- ViGene Biosciences adenoviral particle packaged cDNA for CERS4 gene
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- Santa Cruz Biotechnology (SCBT) Antibodies for CERS4
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- Horizon Cell Lines for CERS4
- Cyagen custom Knockout/knockin (KOKI) mouse models for CERS4
- VectorBuilder custom plasmid, inducible vectors for CERS4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CERS4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for CERS4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer