CERS2 Gene
protein-coding GIFtS: 52
GCID: GC01M150934
|
|
ceramide synthase 2(Previous names: longevity assurance (LAG1, S. cerevisiae) homolog 2, LAG1...) (Previous symbol: LASS2)
| |
Aliases for CERS2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Ceramide Synthase 21 2 | | FLJ102431 | | LASS21 2 3 5 | | LAG1 Longevity Assurance Homolog 2 (S. Cerevisiae)1 | | SP2601 2 3 | | L32 | | LAG1 Homolog, Ceramide Synthase 21 2 | | LAG1 Longevity Assurance 22 | | Longevity Assurance (LAG1, S. Cerevisiae) Homolog 21 2 | | CerS23 | | Tumor Metastasis-Suppressor Gene 1 Protein2 3 | | LAG1 Longevity Assurance Homolog 23 | | TMSG12 3 | | |
Export aliases for CERS2 gene to outside databases |
Summaries for CERS2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CERS2: This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation oroverexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a rolein the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have beendescribed. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: CERS2_HUMAN, Q96G23Function: Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis Gene Wiki entry for CERS2 (LASS2)
|
Genomic Views for CERS2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for CERS2 Other transcription factors
Search SABiosciences Chromatin IP Primers for CERS2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CERS2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q21.3 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21.3CERS2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M150934: view genomic region
(about GC identifiers)
Start:
|
150,933,059 bp from pter |
End:
|
150,947,479 bp from pter |
Size:
|
14,421 bases |
Orientation:
|
minus strand |
|
Proteins for CERS2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CERS2_HUMAN, Q96G23 (See
protein sequence)Recommended Name: Ceramide synthase 2 Size: 380 amino acids; 44876 Da
Subunit: Interacts with ATP6V0C, ASGR1, ASGR2 and SLC22A1/OCT1. Interacts with ELOV1, HSD17B12 and TECR
Subcellular location: Nucleus membrane; Multi-pass membrane protein (Potential). Endoplasmic reticulum membrane;Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=BAA91505.1; Type=Erroneous initiation;
Secondary accessions: D3DV06 Q5SZE5 Q9HD96 Q9NW79Explore the universe of human proteins at neXtProt for CERS2: NX_Q96G23
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96G23 CERS2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_071358.1 NP_859530.1 ENSEMBL proteins: ENSP00000454160 ENSP00000357950 ENSP00000453297 ENSP00000337842 ENSP00000357945 ENSP00000355020 ENSP00000452810 ENSP00000393239 ENSP00000394012 ENSP00000271688 Reactome Protein details: Q96G23 Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
CERS2 for ontologies About GeneDecksing
CERS2 Antibody Products: Assay Products for CERS2: |
Protein
Domains / Families for CERS2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CERS2 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96G23ProtoNet protein and cluster: Q96G23 2 Blocks protein families: IPB005547 Longevity-assurance protein (LAG1) IPB006634 TRAM
UniProtKB/Swiss-Prot: CERS2_HUMAN, Q96G23Similarity: Contains 1 homeobox DNA-binding domainSimilarity: Contains 1 TLC (TRAM/LAG1/CLN8) domain |
Function for CERS2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: CERS2_HUMAN, Q96G23Function: Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CERS2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CERS2 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for CERS2 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CERS2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CERS2  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CERS2 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
-- | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- | | GO:0043565 | sequence-specific DNA binding |
IEA | -- | | GO:0050291 | sphingosine N-acyltransferase activity |
IEA | -- |
CERS2 for ontologies About GeneDecksing
Animal Models: 4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Cers2):
CERS2 for phenotypes About GeneDecksing
|
Pathways & Interactions for CERS2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sphingolipid metabolism | | | 2 | Metabolism | |
Pathway sources See GeneCards unified pathways Show all pathways
4
Reactome Pathways for CERS2
CERS2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CERS2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/67 Interacting proteins for CERS2 (Q96G231, 3 ENSP000002716884) via UniProtKB, MINT, STRING, and/or I2D (see all 67)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| ASGR1 | P073061, 3, ENSP000002692994 | EBI-1057080,EBI-1172335 I2D:
score=3 STRING: ENSP00000269299 | | HSP90AA1 | P079001, 3 | EBI-1057080,EBI-2211817 I2D:
score=1 | | ASGR2 | P073071, 3, ENSP000003471404 | EBI-1057080,EBI-1172636 I2D:
score=3 STRING: ENSP00000347140 | | ATP6V0C | P274491, 3, ENSP000003297574 | EBI-1057080,EBI-721179 I2D:
score=3 STRING: ENSP00000329757 | | SLC22A1 | O152451, 3, ENSP000003559304 | EBI-1057080,EBI-1172714 I2D:
score=3 STRING: ENSP00000355930 | About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006644 | phospholipid metabolic process |
TAS | -- | | GO:0006665 | sphingolipid metabolic process |
TAS | -- | | GO:0030148 | sphingolipid biosynthetic process |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- | | GO:0046513 | ceramide biosynthetic process |
IEA | -- |
CERS2 for ontologies About GeneDecksing
|
Drugs & Compounds for CERS2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CERS2 for compounds About GeneDecksing
Browse Tocris compounds for CERS2 1 Novoseek chemical compound relationship for CERS2 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| maleimide |
80.3 |
2 |
15796876 (1), 15672611 (1) |
Search CenterWatch for drugs/clinical trials and news about CERS2 
|
Transcripts for CERS2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CERS2 gene (3 alternative transcripts): NM_022075.4 NM_181746.3 NM_013384.3 Unigene Cluster for CERS2: Ceramide synthase 2 Hs.744017 [show with all ESTs]Unigene Representative Sequence: NM_18174615 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000482825 ENST00000561294 ENST00000368954(uc001evz.3 uc009wmh.3) ENST00000560793 ENST00000345896 ENST00000460664 ENST00000368949 ENST00000496562 ENST00000361419 ENST00000559660 ENST00000558062 ENST00000559020 ENST00000421609 ENST00000457392 ENST00000271688(uc001evy.3)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CERS2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CERS2 (see all 4) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for CERS2 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CERS2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CERS2  |
Additional cDNA sequence: AF177338.2 AF189062.4 AK001105.1 AK290989.1 AY091458.1 BC001357.2 BC010032.2 24 DOTS entries: DT.95266941 DT.91758853 DT.100835331 DT.97860965 DT.100835330 DT.95125678 DT.121452948 DT.121453027 DT.95266953 DT.121453035 DT.121452946 DT.91758855 DT.100835334 DT.121452942 DT.121453018 DT.100060720 DT.100708569 DT.100792734 DT.100792739 DT.100835339 DT.313478 DT.95093003 DT.95257627 DT.97859023 24/480 AceView cDNA sequences (see all 480): AL554049 BM907435 BI258752 CF132147 BI757217 BQ437940 BU541400 BU543940 BQ219926 AI889883 BQ233443 BU164844 BI028067 CD107846 BM908154 CD675166 BU180987 BM553531 BE162717 BM451302 T34856 CA449459 BQ673270 NM_181746 GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for CERS2 (see all 12) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | |
| SP1: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 12b | ^ | 13a | · | 13b | · | 13c | ^ | 14 | ^ | 15 | |
| SP1: | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CERS2
|
Expression for CERS2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CERS2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GCAATAAGTG
About this image See CERS2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CERS2
SOURCE GeneReport for Unigene cluster: Hs.744017 UniProtKB/Swiss-Prot: CERS2_HUMAN, Q96G23Tissue specificity: Expressed in kidney, liver, brain, heart, placenta and lung SABiosciences Custom PCR Arrays for CERS2
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CERS2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CERS2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CERS2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CERS2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CERS2 |
Orthologs for CERS2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CERS2 gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
LOC1008572621 |
ceramide synthase 2-like |
80.05(n) 84.57(a) |
  |
100857262 XM_003642682.1 XP_003642730.1 |
lizard (Anolis carolinensis) |
Reptilia |
CERS26 |
-- |
78(a) |
1 ↔ 1 |
GL343893.1(128642-141147) |
African clawed frog (Xenopus laevis) |
Amphibia |
BC042311.12 |
-- |
69.3(n) |
  |
BC042311.1 |
zebrafish (Danio rerio) |
Actinopterygii |
trh32 |
trh3 protein |
75.95(n) |
  |
259251 BC045284.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
schlank6 |
schlank |
35(a) |
possible ortholog |
X(6151701-6161260) |
worm (Caenorhabditis elegans) |
Secernentea |
hyl-26hyl-16 |
Homolog of Yeast Longevity gene family member (hyl...Homolog of Yeast Longevity gene family member (hyl... |
27(a)27(a) |
many ↔ manymany ↔ many |
X(4697218-4699433) IV(8540541-8544366) |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
LAG131 |
LAG1 longevity assurance homolog 3 |
46.64(n) 39.91(a) |
  |
837919 NM_001035960.1 NP_001031037.1 |
rice (Oryza sativa) |
Liliopsida |
Os02g05813001 |
hypothetical protein |
46.06(n) 36.36(a) |
  |
4329785 NM_001053779.1 NP_001047244.1 |
ENSEMBL Gene Tree for CERS2 (if available) TreeFam Gene Tree for CERS2 (if available)  |
Paralogs for CERS2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for CERS2 gene
- CERS42 CERS12 CERS62 CERS52 CERS32
5 SIMAP similar genes for CERS2 using alignment to 9 protein entries: CERS2_HUMAN (see all proteins):CERS4 CERS3 CERS6 CERS5 LASS5
CERS2 for paralogs About GeneDecksing
|
Genomic Variants for CERS2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CERS2 (150933059 - 150947479 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for CERS2: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CERS2 |
|
Disorders
/ Diseases for CERS2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CERS2 for disorders About GeneDecksing
OMIM gene information: 606920
OMIM disorders: --
3 diseases for CERS2: About MalaCardskidney disease breast cancer malaria
3 Novoseek disease relationships for CERS2 gene About this table
Export disorders for CERS2 gene to outside databases
|
Publications for CERS2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CERS2 gene, integrated from 9 sources (see all 38): (articles sorted by number of sources associating them with CERS2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1. (PubMed id 11543633)1, 2, 3, 9 Pan H....Gu J.-R. (2001)
- Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach. (PubMed id 16263699)1, 2 Lewandrowski U.... Sickmann A. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Silencing of a novel tumor metastasis suppressor gene LASS2/TMSG1 promotes invasion of prostate cancer cell in vitro through increase of vacuolar ATPase activity. (PubMed id 22573553)1 Xu X....Pei F. (2012)
- Global landscape of HIV-human protein complexes. (PubMed id 22190034)1 Jager S....Krogan N.J. (2012)
- KLF6/Sp1 initiates transcription of the tmsg-1 gene in human prostate carcinoma cells: an exon involved mechanism. (PubMed id 21928351)1 Gong M....Zheng J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
|
External Searches for CERS2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CERS2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CERS2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CERS2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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| Name | Description |
| PharmGKB entry for CERS2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for CERS2 gene: Search GeneIP for patents involving CERS2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for CERS2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for CERS2 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CERS2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CERS2 | | OriGene Protein Over-expression Lysate for CERS2 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CERS2 | | OriGene 3'-UTR Clone for CERS2 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CERS2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CERS2 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for CERS2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CERS2 | | OriGene Custom Protein Services for CERS2 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CERS2 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CERS2 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CERS2 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CERS2 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CERS2 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CERS2 |
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| | | Search Tocris compounds for CERS2 |
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 | | CERS2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CERS2 |
|  |  |  | | | ThermoFisher Antibodies for CERS2 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CERS2 |
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