CERKL Gene
protein-coding GIFtS: 47
GCID: GC02M182401
|
|
ceramide kinase-like(Previous name: retinitis pigmentosa 26 (autosomal recessive) )
(Previous symbol: RP26)
| |
Aliases
for CERKL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Ceramide Kinase-Like1 2 | | RP261 2 5 | | Retinitis Pigmentosa 26 (Autosomal Recessive)1 | | Ceramide Kinase-Like Protein2 |
| External Ids: | HGNC: 216991 | Entrez Gene: 3752982 | Ensembl: ENSG000001884527 | OMIM: 6083815 | UniProtKB: Q49MI33 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n407974 | |
Export aliases for CERKL gene to outside databasesPrevious GC identifers: GC02M182229 GC02M182109 GC02M174258
Summaries
for CERKL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CERKL:
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitispigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein doesnot phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator ofapoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized byautosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcriptvariants encoding different isoforms and non-coding transcripts.(provided by RefSeq, May 2010)
UniProtKB/Swiss-Prot: CERKL_HUMAN, Q49MI3Function: Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis inoxidative stress conditions
|
Genomic Views
for CERKL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CERKL gene promoter:
AREB6 POU3F1 p300 FOXO3 FOXD3 IRF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CERKL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CERKL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q31.3 Ensembl cytogenetic band: 2q31.3 HGNC cytogenetic band: 2q31.3CERKL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M182401: view genomic region
(about GC identifiers)
Start:
|
182,401,399 bp from pter |
End:
|
182,545,392 bp from pter |
Size:
|
143,994 bases |
Orientation:
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minus strand |
|
Proteins
for CERKL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CERKL_HUMAN, Q49MI3 (See
protein sequence)Recommended Name: Ceramide kinase-like protein Size: 558 amino acids; 62622 Da
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Enriched in nucleoli. May shuttle between nucleus andcytoplasm. Isoform 5 is not enriched in the nucleoli
Subcellular location: Isoform 2: Cytoplasm. Nucleus, nucleolus. Golgi apparatus, trans-Golgi network. Endoplasmicreticulum
Developmental stage: Expressed in fetal lung, kidney and brain
Sequence caution: Sequence=BAC85266.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=CAG26980.1;Type=Frameshift; Positions=Several;
Secondary accessions: B2RPL2 B4DEY1 Q49MH9 Q49MI0 Q49MI1 Q49MI2 Q5DVJ2 Q5DVJ4 Q5DVJ5 Q6UZF6 Q6ZP59Alternative splicing: 8 isoforms: Q49MI3-1 Q49MI3-2 Q49MI3-3 Q49MI3-4 Q49MI3-5 Q49MI3-7 Q49MI3-8 Q49MI3-9 (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)Explore the universe of human proteins at neXtProt for CERKL: NX_Q49MI3
Post-translational modifications:
Phosphorylated on serine residues1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q49MI3
CERKL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001025482.1 NP_001025483.1 NP_001025484.1 NP_001153749.1 NP_963842.1
ENSEMBL proteins: ENSP00000386725 ENSP00000387080 ENSP00000364108 ENSP00000409198 ENSP00000341159 ENSP00000364109 ENSP00000364106 ENSP00000411466
Human Recombinant Protein Products for CERKL:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CERKL for ontologies About GeneDecksing
CERKL Antibody Products:
Assay Products for CERKL: |
Protein
Domains /
Families
for CERKL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CERKL for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q49MI3ProtoNet protein and cluster: Q49MI3 UniProtKB/Swiss-Prot: CERKL_HUMAN, Q49MI3Similarity: Contains 1 DAGKc domain |
Function
for CERKL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CERKL_HUMAN, Q49MI3Function: Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis inoxidative stress conditions Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004143 | diacylglycerol kinase activity |
IEA | -- |
CERKL for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CERKL:
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Cerkl):
CERKL for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CERKL (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CERKL (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): CERKL (NM_001030311) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CERKL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CERKL |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CERKL |
|
Pathways & Interactions
for CERKL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CERKL
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway |
IEA | -- | | GO:0043066 | negative regulation of apoptotic process |
IDA | 19158957 |
CERKL for ontologies About GeneDecksing
|
Drugs & Compounds
for CERKL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CERKL for compounds About GeneDecksing
 Browse Tocris compounds for CERKL
1 PharmGKB related drug/compound annotation for CERKL gene About this tableSearch CenterWatch for drugs/clinical trials and news about CERKL
|
Transcripts
for CERKL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CERKL gene (5 alternative transcripts): NM_001030311.2 NM_001030312.2 NM_001030313.2 NM_001160277.1 NM_201548.4 Unigene Cluster for CERKL: Ceramide kinase-like Hs.732358 [show with all ESTs]Unigene Representative Sequence: NM_00103031114 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000410087(uc002unw.3 uc002unx.3 uc010frk.3 uc002uny.3 uc010zfm.2 uc002unz.3 uc002uoa.3 uc002uob.3 uc002uoc.3 uc021vth.1 uc021vti.1 uc021vtj.1 uc021vtk.1 uc021vtl.1 uc021vtm.1 uc002uod.2)
ENST00000409440 ENST00000374969 ENST00000452174 ENST00000339098 ENST00000374970
ENST00000374967 ENST00000494398(uc002uoe.3) ENST00000421817 ENST00000479558
ENST00000466715 ENST00000460319 ENST00000476070 ENST00000497337
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CERKL (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CERKL (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): CERKL (NM_001030311) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CERKL | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CERKL |
Additional cDNA sequence: AJ640141.1 AJ697858.1 AK129976.1 AK293844.1 AY357073.1 AY690329.1 AY690330.1 AY690331.1 BC137498.1 BC137499.1 HQ426666.1 HQ426667.1 HQ426668.1 HQ426669.1 HQ426670.1 HQ426671.1 HQ426672.1 HQ426673.1 HQ426674.1 HQ426675.1 HQ426676.1 HQ426677.1 HQ426678.1 HQ426679.1 JF290420.1 NR_027689.1 NR_027690.1 6 DOTS entries: DT.100757359 DT.99946353 DT.438156 DT.120966502 DT.120966656 DT.97840348 24/29 AceView cDNA sequences (see all 29): AY357073 AI906687 NM_201548 AI273051 R85727 BM979388 BE501780 AW148543 AI769736 BM983875 BM969366 AK129976 CA941582 CA941289 AI935410 BU689441 BC020465 BE797822 BE781384 AW968736 AW880375 AW299362 AW058563 H95691
GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CERKL (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | | | | | - | | - | | - | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CERKL
|
Expression
for CERKL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CERKL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATACAAGTAA
About this image
See CERKL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CERKL
SOURCE GeneReport for Unigene cluster: Hs.732358
UniProtKB/Swiss-Prot: CERKL_HUMAN, Q49MI3Tissue specificity: Isoform 1 and isoform 2 are expressed in adult retina, liver and pancreas as well as in fetalbrain, lung and kidney. Isoform 3 is expressed in adult retina as well as in fetal lung and liver. Isoform 4 isexpressed in adult retina, lung and kidney as well as in fetal lung and liver. Moderately expressed in retina, kidney,lung, testis, trachea, and pancreas. Weakly expressed in brain, placenta and liver
SABiosciences Custom PCR Arrays for CERKL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CERKL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CERKL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CERKL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CERKL | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CERKL |
Orthologs
for CERKL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CERKL gene from 4/14 species (see all 14) About this table
ENSEMBL Gene Tree for CERKL (if available)
TreeFam Gene Tree for CERKL (if available) |
Paralogs
for CERKL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CERKL gene
- SPHK12 CERK2 SPHK22 AGK2
CERKL for paralogs About GeneDecksing
|
Genomic Variants
for CERKL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CERKL (182401399 - 182545392 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CERKL
2 CNVs: 90163 78887
Human Gene Mutation Database (HGMD): CERKL
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CERKL |
|
Disorders
/ Diseases
for CERKL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CERKL for disorders About GeneDecksing
OMIM gene information: 608381
OMIM disorders: 608380
UniProtKB/Swiss-Prot: CERKL_HUMAN, Q49MI3
Defects in CERKL are the cause of retinitis pigmentosa type 26 (RP26) [MIM:608380]. RP leads to degenerationof retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field.As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP26inheritance is autosomal recessive
9  diseases for CERKL: About MalaCardsretinitis pigmentosa cone-rod dystrophy retinitis pigmentosa 26 retinitis
fundus dystrophy retinal degeneration retinal disease blindness
schizophrenia
2 diseases from the University of Copenhagen DISEASES database for CERKL:Retinitis pigmentosa cone-rod dystrophy Human Genome Epidemiology (HuGE) Navigator: CERKL (9 documents)
Export disorders for CERKL gene to outside databases
|
Publications
for CERKL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CERKL gene, integrated from 9 sources (see all 27):
(articles sorted by number of sources associating them with CERKL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutation of CERKL, a novel human ceramide kinase gene, causes autosomal recessive retinitis pigmentosa (RP26). (PubMed id 14681825)1, 2, 3, 9 Tuson M.... Gonzalez-Duarte R. (2004)
- Characterization of a ceramide kinase-like protein. (PubMed id 15708351)1, 2, 9 Bornancin F.... Billich A. (2005)
- Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress. (PubMed id 19158957)1, 2, 9 Tuson M....Marfany G. (2009)
- Subcellular localization of ceramide kinase and ceram ide kinase-like protein requires interplay of their Pleckstrin Homology domain- containing N-terminal regions together with C-terminal domains. (PubMed id 19501188)1, 2, 9 Rovina P....Bornancin F. (2009)
- A missense mutation in the nuclear localization signal sequence of CERKL (p.R106S) causes autosomal recessive retinal degeneration. (PubMed id 18978954)1, 2, 9 Ali M....Inglehearn C.F. (2008)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- CERKL mutations and associated phenotypes in seven Spanish families with autosomal recessive retinitis pigmentosa. (PubMed id 18515597)1, 9 Avila-Fernandez A....Ayuso C. (2008)
- Identification of a nuclear localization signal in the retinitis pigmentosa-mutated RP26 protein, ceramide kinase-like protein. (PubMed id 16581028)1, 9 Inagaki Y....Igarashi Y. (2006)
- High Transcriptional Complexity of the Retinitis Pigmentosa CERKL Gene in Human and Mouse. (PubMed id 21508105)1 Garanto A.... Gonzalez-Duarte R. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
|
External Searches for CERKL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CERKL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CERKL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CERKL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CERKL | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CERKL gene:
Search GeneIP for patents involving CERKL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CERKL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CERKL | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CERKL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CERKL | | | OriGene Protein Over-expression Lysate for CERKL | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CERKL | | OriGene 3'-UTR Clone for CERKL | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CERKL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CERKL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CERKL | | OriGene Custom Protein Services for CERKL | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CERKL | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CERKL | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CERKL | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CERKL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CERKL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CERKL |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CERKL |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CERKL |
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GeneCards Homepage -
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