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CEP97 Gene

protein-coding   GIFtS: 46
GCID: GC03P101442

Centrosomal Protein 97kDa

(Previous name: leucine-rich repeats and IQ motif containing 2)
(Previous symbol: LRRIQ2)
  Search for CEP97
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Centrosomal Protein 97kDa1 2     2810403B08Rik2
LRRIQ21 2 3     Centrosomal Protein Of 97 KDa2
Leucine-Rich Repeats And IQ Motif Containing 21 2     Cep973
Leucine-Rich Repeat And IQ Domain-Containing Protein 22 3     

External Ids:    HGNC: 262441   Entrez Gene: 795982   Ensembl: ENSG000001825047   UniProtKB: Q8IW353   

Export aliases for CEP97 gene to outside databases

Previous GC identifers: GC03P102927 GC03P098812


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CEP97 Gene:
CEP97 (centrosomal protein 97kDa) is a protein-coding gene. GO annotations related to this gene include calmodulin binding.

UniProtKB/Swiss-Prot: CEP97_HUMAN, Q8IW35
Function: Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother
centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome

Gene Wiki entry for CEP97 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CEP97 gene promoter:
         HTF   CUTL1   STAT5A   POU6F1 (c2)   E4BP4   POU3F2   Gfi-1   MEF-2A   aMEF-2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCEP97 promoter sequence
   Search Chromatin IP Primers for CEP97

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEP97


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q12.3   Ensembl cytogenetic band:  3q12.3   HGNC cytogenetic band: 3q12.3

CEP97 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEP97 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P101442:  view genomic region     (about GC identifiers)

Start:
101,442,769 bp from pter      End:
101,489,406 bp from pter
Size:
46,638 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CEP97_HUMAN, Q8IW35 (See protein sequence)
Recommended Name: Centrosomal protein of 97 kDa  
Size: 865 amino acids; 96981 Da
Subunit: Interacts with CALM1, CEP76 and CCP110. Via its interaction with CCP110, may indirectly interact with
HERC2 and NEURL4. Interacts with KIF24
Sequence caution: Sequence=BAB15531.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAC04055.1; Type=Frameshift; Positions=303;
Secondary accessions: B5MDY8 Q8NA71 Q9H5T9
Alternative splicing: 2 isoforms:  Q8IW35-1   Q8IW35-2   (No experimental confirmation available. Sequence incomplete)

Explore the universe of human proteins at neXtProt for CEP97: NX_Q8IW35

Explore proteomics data for CEP97 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CEP97 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_078824.2  
    ENSEMBL proteins: 
     ENSP00000342510   ENSP00000418185   ENSP00000419009   ENSP00000418547   ENSP00000325881  

    CEP97 Human Recombinant Protein Products:

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    Novus Biologicals CEP97 Protein
    Novus Biologicals CEP97 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CEP97

     
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    Search eBioscience for ELISAs for CEP97 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR001611 Leu-rich_rpt
     IPR000048 IQ_motif_EF-hand-BS

    Graphical View of Domain Structure for InterPro Entry Q8IW35

    ProtoNet protein and cluster: Q8IW35

    UniProtKB/Swiss-Prot: CEP97_HUMAN, Q8IW35
    Similarity: Contains 1 IQ domain
    Similarity: Contains 8 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain


    Find genes that share domains with CEP97           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CEP97_HUMAN, Q8IW35
    Function: Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother
    centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17719545
    GO:0005516calmodulin binding IEA--
         
    Find genes that share ontologies with CEP97           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CEP97
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CEP97

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CEP97
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CEP97

    miRNA
    Products:
        
    miRTarBase miRNAs that target CEP97:
    hsa-mir-21-5p (MIRT030967), hsa-mir-92a-3p (MIRT048944)

    Block miRNA regulation of human, mouse, rat CEP97 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CEP97 (see all 29):
    hsa-miR-142-5p hsa-miR-106a hsa-miR-29c hsa-miR-29a hsa-miR-1271 hsa-miR-519a hsa-miR-410 hsa-miR-3167
    SwitchGear 3'UTR luciferase reporter plasmidCEP97 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat CEP97

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: CEP97 (NM_024548)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEP97
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEP97

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CEP97 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP97


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CEP97_HUMAN, Q8IW35: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus4
    cytosol3
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005737cytoplasm IDA--
    GO:0005813centrosome IDA--
    GO:0005815microtubule organizing center IDA--

    Find genes that share ontologies with CEP97           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CEP97
    Interactions:

        GeneGlobe Interaction Network for CEP97

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for CEP97 (Q8IW351, 2, 3 ENSP000003425104) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCP110O433031, 2, 3EBI-1566210,EBI-1566217 MINT-8396999 MINT-8396578 MINT-8396594 MINT-8396494 MINT-8396609 I2D: score=3 
    CEP290O150782, ENSP000003080214MINT-8396578 MINT-8396594 MINT-8396494 MINT-8396609 STRING: ENSP00000308021
    CEP76Q8TAP62, ENSP000002621274MINT-8396578 MINT-8396594 MINT-8396494 MINT-8396609 STRING: ENSP00000262127
    CALM1P621583, ENSP000003494674I2D: score=2 STRING: ENSP00000349467
    NEURL4Q96JN82MINT-8396999 MINT-8396578 MINT-8396594 MINT-8396494
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030030cell projection organization IEA--

    Find genes that share ontologies with CEP97           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CEP97



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CEP97 gene: 
    NM_024548.2  

    Unigene Cluster for CEP97:

    Centrosomal protein 97kDa
    Hs.444135  [show with all ESTs]
    Unigene Representative Sequence: AL833269
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000341893(uc003dvk.1) ENST00000489172(uc010hpm.1) ENST00000494050
    ENST00000465011 ENST00000467655 ENST00000462076 ENST00000327230(uc011bhf.1 uc003dvl.1 uc003dvm.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CEP97 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CEP97 (see all 29):
    hsa-miR-142-5p hsa-miR-106a hsa-miR-29c hsa-miR-29a hsa-miR-1271 hsa-miR-519a hsa-miR-410 hsa-miR-3167
    SwitchGear 3'UTR luciferase reporter plasmidCEP97 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CEP97
    Predesigned siRNA for gene silencing in human, mouse, rat CEP97
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CEP97 (NM_024548)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEP97
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEP97
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CEP97
    OriGene qSTAR qPCR primer pairs in human, mouse for CEP97
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CEP97
      QuantiTect SYBR Green Assays in human, mouse, rat CEP97
      QuantiFast Probe-based Assays in human, mouse, rat CEP97

    Additional mRNA sequence: 

    AK026700.1 AK093100.1 AK225573.1 AK294784.1 AK309806.1 AL833269.1 BC041085.1 

    5 DOTS entries:

    DT.305045  DT.100026981  DT.100026979  DT.101985994  DT.120924216 

    Selected AceView cDNA sequences (see all 72):

    AL598664 CR605625 R02513 AK093100 BC041085 AL602237 BU179261 AW169839 
    AA911641 F08229 AI078202 AX747922 NM_024548 BM449694 BX493771 BV183146 
    D61605 AW273802 BI820287 BG714925 AA883862 AL703387 BI093308 AA970461 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CEP97    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12a · 12b
    SP1:                                                                          -               
    SP2:                          -                       -                                       


    ECgene alternative splicing isoforms for CEP97

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CEP97 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CEP97 Expression
    About this image


    CEP97 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Limb (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Bone (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
     
     Cartilage (Muscoskeletal System)
             Mesenchymal Condensate Cells Zeugopod
    CEP97 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CEP97 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.444135
        Custom PCR Arrays for CEP97
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP97

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CEP97 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cep971 , 5 centrosomal protein 971, 5 80.67(n)1
    77.7(a)1
      16 (33.69 cM)5
    742011  NM_028815.41  NP_083091.11 
     558998885 
    chicken
    (Gallus gallus)
    Aves CEP971 centrosomal protein 97kDa 65.6(n)
    60.17(a)
      418402  XM_416617.3  XP_416617.2 
    lizard
    (Anolis carolinensis)
    Reptilia CEP976
    centrosomal protein 97kDa
    53(a)
    1 ↔ 1
    3(173555298-173579275)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.74062 Xenopus laevis transcribed sequence with weak similarity more 75.82(n)    CA792511.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc638562 zgc63856 74.07(n)   386640  BC053114.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Cep976
    --
    27(a)
    1 ↔ 1
    2L(3867714-3871425)
    worm
    (Caenorhabditis elegans)
    Secernentea R02F11.46
    Protein R02F11.4 (R02F11.4) mRNA, complete cds
    20(a)
    1 ↔ 1
    V(4810927-4818663) WBGene00019842


    ENSEMBL Gene Tree for CEP97 (if available)
    TreeFam Gene Tree for CEP97 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CEP97 (see all 846)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1829287651,2
    --98810359(+) AAAATC/TCTAGT 1 -- us2k10--------
    rs738633821,2
    C,F--98810416(+) AGCAGG/AAAACA 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1866943281,2
    --98810686(+) ACTTCA/GTTACC 1 -- us2k10--------
    rs1907785101,2
    --98810693(+) TACCAC/TCTGCA 1 -- us2k10--------
    rs1830205931,2
    --98810727(+) TACTTC/TAGAAC 1 -- us2k10--------
    rs1866968501,2
    --98810766(+) GGGTAA/CATTTA 1 -- us2k10--------
    rs1922987221,2
    --98810792(+) CTTCAC/TTGAAG 1 -- us2k10--------
    rs731592571,2
    C--98810861(+) ACACCA/GTTTAG 1 -- us2k10--------
    rs117207451,2
    C,F,H--98810942(+) CTGAGG/ACAGAA 1 -- us2k116Minor allele frequency- A:0.17NS EA WA NA CSA 796
    rs1850508311,2
    --98811078(+) TAAATA/GTATAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CEP97 (101442769 - 101489406 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for CEP97:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2725709CNV Deletion23290073
    esv2725708CNV Deletion23290073
    esv2350180CNV Deletion18987734

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CEP97
    DNA2.0 Custom Variant and Variant Library Synthesis for CEP97

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CEP97 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with CEP97)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cep97 and CP110 suppress a cilia assembly program. (PubMed id 17719545)1, 2, 3 Spektor A.... Dynlacht B.D. (Cell 2007)
    2. Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture. (PubMed id 22261722)1, 2 Al-Hakim A.K.... Pelletier L. (Mol. Cell. Proteomics 2012)
    3. Cep76, a centrosomal protein that specifically restrains centriole reduplication. (PubMed id 19460342)1, 2 Tsang W.Y.... Dynlacht B.D. (Dev. Cell 2009)
    4. Double life of centrioles: CP110 in the spotlight. (PubMed id 18068367)1, 3 Bettencourt-Dias M. and Carvalho-Santos Z. (Trends Cell Biol. 2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110. (PubMed id 23486064)1 Li J.... Dynlacht B.D. (Nature 2013)
    8. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    9. Neurl4, a novel daughter centriole protein, prevents formation of ectopic microtubule organizing centres. (PubMed id 22441691)1 Li J....Dynlacht B.D. (EMBO Rep. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79598 HGNC: 26244 AceView: LRRIQ2 Ensembl:ENSG00000182504 euGenes: HUgn79598
    ECgene: CEP97 H-InvDB: CEP97

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CEP97 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CEP97 gene:
    Search GeneIP for patents involving CEP97

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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