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Aliases for CEP95 Gene

Aliases for CEP95 Gene

  • Centrosomal Protein 95kDa 2 3
  • Coiled-Coil Domain-Containing Protein 45 3 4
  • Coiled-Coil Domain Containing 45 2 3
  • CCDC45 3 4
  • Centrosomal Protein Of 95 KDa 3
  • CEP45 4
  • Cep95 4

External Ids for CEP95 Gene

Previous HGNC Symbols for CEP95 Gene

  • CCDC45

Previous GeneCards Identifiers for CEP95 Gene

  • GC17P062502

Summaries for CEP95 Gene

GeneCards Summary for CEP95 Gene

CEP95 (Centrosomal Protein 95kDa) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEP95 Gene

Genomics for CEP95 Gene

Genomic Location for CEP95 Gene

Start:
64,506,588 bp from pter
End:
64,542,461 bp from pter
Size:
35,874 bases
Orientation:
Plus strand

Genomic View for CEP95 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CEP95 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEP95 Gene

No data available for Regulatory Elements for CEP95 Gene

Proteins for CEP95 Gene

  • Protein details for CEP95 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96GE4-CEP95_HUMAN
    Recommended name:
    Centrosomal protein of 95 kDa
    Protein Accession:
    Q96GE4
    Secondary Accessions:
    • B4DMD2
    • Q96M81

    Protein attributes for CEP95 Gene

    Size:
    821 amino acids
    Molecular mass:
    95297 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CEP95 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CEP95 Gene

Proteomics data for CEP95 Gene at MOPED

Post-translational modifications for CEP95 Gene

  • Ubiquitination at Lys320, Lys387, and Lys704
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CEP95 Gene

Domains for CEP95 Gene

Protein Domains for CEP95 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CEP95 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CEP95: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CEP95 Gene

Function for CEP95 Gene

Gene Ontology (GO) - Molecular Function for CEP95 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CEP95: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CEP95 Gene

Localization for CEP95 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEP95 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.

Gene Ontology (GO) - Cellular Components for CEP95 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IDA 21399614
GO:0005737 cytoplasm IEA --
GO:0005813 centrosome IDA 21399614
genes like me logo Genes that share ontologies with CEP95: view

No data available for Subcellular locations from COMPARTMENTS for CEP95 Gene

Pathways for CEP95 Gene

SuperPathways for CEP95 Gene

No Data Available

Interacting Proteins for CEP95 Gene

Gene Ontology (GO) - Biological Process for CEP95 Gene

None

No data available for Pathways by source for CEP95 Gene

Transcripts for CEP95 Gene

Unigene Clusters for CEP95 Gene

Centrosomal protein 95kDa:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CEP95

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CEP95
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CEP95 Gene

No ASD Table

Relevant External Links for CEP95 Gene

GeneLoc Exon Structure for
CEP95
ECgene alternative splicing isoforms for
CEP95

Expression for CEP95 Gene

mRNA expression in normal human tissues for CEP95 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CEP95 Gene

SOURCE GeneReport for Unigene cluster for CEP95 Gene Hs.569713

genes like me logo Genes that share expressions with CEP95: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CEP95 Gene

Orthologs for CEP95 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CEP95 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CEP95 35
  • 99.35 (n)
  • 98.78 (a)
CEP95 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CEP95 35
  • 88.41 (n)
  • 83.23 (a)
CEP95 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CEP95 35
  • 87.81 (n)
  • 83 (a)
CEP95 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cep95 35
  • 79.85 (n)
  • 73.96 (a)
Cep95 16
Cep95 36
  • 73 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CEP95 36
  • 51 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CEP95 36
  • 50 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cep95 35
  • 78.64 (n)
  • 73.09 (a)
chicken
(Gallus gallus)
Aves CEP95 35
  • 61.97 (n)
  • 54.12 (a)
CEP95 36
  • 46 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CEP95 36
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cep95 35
  • 56.76 (n)
  • 50.91 (a)
Str.11457 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 39 (a)
OneToMany
CSA.6755 36
  • 27 (a)
OneToMany
Species with no ortholog for CEP95:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CEP95 Gene

ENSEMBL:
Gene Tree for CEP95 (if available)
TreeFam:
Gene Tree for CEP95 (if available)

Paralogs for CEP95 Gene

genes like me logo Genes that share paralogs with CEP95: view

No data available for Paralogs for CEP95 Gene

Variants for CEP95 Gene

Sequence variations from dbSNP and Humsavar for CEP95 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs2303574 -- 64,514,164(-) CATTG(C/T)GAAAA intron-variant
rs2303575 -- 64,532,061(-) AAAGG(C/T)TGCCA intron-variant, downstream-variant-500B, nc-transcript-variant
rs2313444 -- 64,511,366(-) ccccc(A/G)ggcgt intron-variant
rs4790970 -- 64,530,878(-) CACAA(C/T)GGGCA intron-variant
rs4791276 -- 64,517,300(-) ggagg(A/C)caagg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CEP95 Gene

Variant ID Type Subtype PubMed ID
nsv819879 CNV Gain 19587683
nsv828085 CNV Loss 20364138

Relevant External Links for CEP95 Gene

HapMap Linkage Disequilibrium report
CEP95

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CEP95 Gene

Disorders for CEP95 Gene

No disorders were found for CEP95 Gene.

No data available for UniProtKB/Swiss-Prot for CEP95 Gene

Publications for CEP95 Gene

  1. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. (PMID: 21399614) Jakobsen L. … Andersen J.S. (EMBO J. 2011) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  5. A human MAP kinase interactome. (PMID: 20936779) Bandyopadhyay S. … Ideker T. (Nat. Methods 2010) 3

Products for CEP95 Gene

Sources for CEP95 Gene

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