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Aliases for CEP78 Gene

Aliases for CEP78 Gene

  • Centrosomal Protein 78 2 3
  • Centrosomal Protein 78kDa 2 3 5
  • C9orf81 3 4
  • Chromosome 9 Open Reading Frame 81 2
  • Cep78 4
  • IP63 3

External Ids for CEP78 Gene

Previous HGNC Symbols for CEP78 Gene

  • C9orf81

Previous GeneCards Identifiers for CEP78 Gene

  • GC09P078081
  • GC09P080040
  • GC09P080850
  • GC09P050682

Summaries for CEP78 Gene

GeneCards Summary for CEP78 Gene

CEP78 (Centrosomal Protein 78) is a Protein Coding gene. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance.

Gene Wiki entry for CEP78 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEP78 Gene

Genomics for CEP78 Gene

Regulatory Elements for CEP78 Gene

Enhancers for CEP78 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CEP78 on UCSC Golden Path with GeneCards custom track

Promoters for CEP78 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CEP78 on UCSC Golden Path with GeneCards custom track

Genomic Location for CEP78 Gene

78,236,062 bp from pter
78,279,690 bp from pter
43,629 bases
Plus strand

Genomic View for CEP78 Gene

Genes around CEP78 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CEP78 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CEP78 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEP78 Gene

Proteins for CEP78 Gene

  • Protein details for CEP78 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Centrosomal protein of 78 kDa
    Protein Accession:
    Secondary Accessions:
    • A1A4S8
    • E9PHX5
    • Q5BJE3
    • Q5JTW0
    • Q5JTW1
    • Q9H9N3

    Protein attributes for CEP78 Gene

    689 amino acids
    Molecular mass:
    76396 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH91515.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH91515.1; Type=Miscellaneous discrepancy; Note=Probable intron retention.; Evidence={ECO:0000305};

    Alternative splice isoforms for CEP78 Gene


neXtProt entry for CEP78 Gene

Proteomics data for CEP78 Gene at MOPED

Post-translational modifications for CEP78 Gene

  • Ubiquitination at Lys 90, Lys 317, and Lys 374
  • Modification sites at PhosphoSitePlus

Other Protein References for CEP78 Gene

No data available for DME Specific Peptides for CEP78 Gene

Domains & Families for CEP78 Gene

Protein Domains for CEP78 Gene


Suggested Antigen Peptide Sequences for CEP78 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CEP78 family.
  • Belongs to the CEP78 family.
genes like me logo Genes that share domains with CEP78: view

No data available for Gene Families for CEP78 Gene

Function for CEP78 Gene

genes like me logo Genes that share phenotypes with CEP78: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CEP78 Gene

Localization for CEP78 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEP78 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Subcellular locations from

Jensen Localization Image for CEP78 Gene COMPARTMENTS Subcellular localization image for CEP78 gene
Compartment Confidence
cytoskeleton 5
cytosol 5
nucleus 2

No data available for Gene Ontology (GO) - Cellular Components for CEP78 Gene

Pathways & Interactions for CEP78 Gene

genes like me logo Genes that share pathways with CEP78: view

Gene Ontology (GO) - Biological Process for CEP78 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000278 mitotic cell cycle TAS --
genes like me logo Genes that share ontologies with CEP78: view

No data available for SIGNOR curated interactions for CEP78 Gene

Drugs & Compounds for CEP78 Gene

No Compound Related Data Available

Transcripts for CEP78 Gene

Unigene Clusters for CEP78 Gene

Centrosomal protein 78kDa:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CEP78 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c · 13d ^ 14a · 14b ^ 15 ^ 16a · 16b · 16c ·
SP1: - - - -
SP2: - - -
SP4: -
SP5: -
SP7: - - - - - - - - - - - - - - - - - - - - -

ExUns: 16d

Relevant External Links for CEP78 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CEP78 Gene

mRNA expression in normal human tissues for CEP78 Gene

Protein differential expression in normal tissues from HIPED for CEP78 Gene

This gene is overexpressed in Testis (28.4), Peripheral blood mononuclear cells (23.5), and CD8 Tcells (11.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for CEP78 Gene

SOURCE GeneReport for Unigene cluster for CEP78 Gene Hs.374421

genes like me logo Genes that share expression patterns with CEP78: view

Protein tissue co-expression partners for CEP78 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CEP78 Gene

Orthologs for CEP78 Gene

This gene was present in the common ancestor of animals.

Orthologs for CEP78 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CEP78 35
  • 88.73 (n)
  • 85.73 (a)
CEP78 36
  • 75 (a)
(Canis familiaris)
Mammalia CEP78 35
  • 89.1 (n)
  • 87.4 (a)
CEP78 36
  • 77 (a)
(Mus musculus)
Mammalia Cep78 35
  • 81.53 (n)
  • 79.69 (a)
Cep78 16
Cep78 36
  • 71 (a)
(Pan troglodytes)
Mammalia CEP78 35
  • 99.35 (n)
  • 99.19 (a)
CEP78 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Cep78 35
  • 82.17 (n)
  • 79.23 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 56 (a)
-- 36
  • 64 (a)
-- 36
  • 49 (a)
-- 36
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia CEP78 36
  • 53 (a)
(Gallus gallus)
Aves CEP78 35
  • 66.16 (n)
  • 63.04 (a)
CEP78 36
  • 50 (a)
(Anolis carolinensis)
Reptilia CEP78 36
  • 48 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cep78 35
  • 62.63 (n)
  • 60.71 (a)
Str.11363 35
(Danio rerio)
Actinopterygii cep78 35
  • 56.77 (n)
  • 53.38 (a)
cep78 36
  • 44 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2778 35
fruit fly
(Drosophila melanogaster)
Insecta CG7886 36
  • 18 (a)
Species with no ortholog for CEP78:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CEP78 Gene

Gene Tree for CEP78 (if available)
Gene Tree for CEP78 (if available)

Paralogs for CEP78 Gene

No data available for Paralogs for CEP78 Gene

Variants for CEP78 Gene

Sequence variations from dbSNP and Humsavar for CEP78 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs928390 -- 78,239,363(+) ATGCC(C/T)ACGCA intron-variant
rs966592 -- 78,235,677(+) GCCTC(C/T)GCCTC upstream-variant-2KB
rs1057650 -- 78,264,233(-) TCCAG(A/G)ATCAT reference, synonymous-codon
rs1065334 -- 78,266,855(+) AAATA(C/T)GTTTC intron-variant, utr-variant-3-prime
rs1571776 -- 78,239,585(-) TTTTA(C/T)CTCAC intron-variant

Variation tolerance for CEP78 Gene

Residual Variation Intolerance Score: 67.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.65; 45.64% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CEP78 Gene

Disorders for CEP78 Gene

Relevant External Links for CEP78

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CEP78 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CEP78 Gene

Publications for CEP78 Gene

  1. Proteomic characterization of the human centrosome by protein correlation profiling. (PMID: 14654843) Andersen J.S. … Mann M. (Nature 2003) 2 3 4 67
  2. Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways. (PMID: 25192599) Wang T. … Xu J. (Neurobiol. Aging 2015) 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3

Products for CEP78 Gene

Sources for CEP78 Gene