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Aliases for CEP78 Gene

Aliases for CEP78 Gene

  • Centrosomal Protein 78kDa 2 3
  • C9orf81 3 4
  • Chromosome 9 Open Reading Frame 81 2
  • Centrosomal Protein Of 78 KDa 3
  • Cep78 4
  • IP63 3

External Ids for CEP78 Gene

Previous HGNC Symbols for CEP78 Gene

  • C9orf81

Previous GeneCards Identifiers for CEP78 Gene

  • GC09P078081
  • GC09P080040
  • GC09P080850
  • GC09P050682

Summaries for CEP78 Gene

GeneCards Summary for CEP78 Gene

CEP78 (Centrosomal Protein 78kDa) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Cell Cycle, Mitotic.

Gene Wiki entry for CEP78 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEP78 Gene

Genomics for CEP78 Gene

Regulatory Elements for CEP78 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CEP78 Gene

78,236,062 bp from pter
78,279,690 bp from pter
43,629 bases
Plus strand

Genomic View for CEP78 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CEP78 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEP78 Gene

Proteins for CEP78 Gene

  • Protein details for CEP78 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Centrosomal protein of 78 kDa
    Protein Accession:
    Secondary Accessions:
    • A1A4S8
    • E9PHX5
    • Q5BJE3
    • Q5JTW0
    • Q5JTW1
    • Q9H9N3

    Protein attributes for CEP78 Gene

    689 amino acids
    Molecular mass:
    76396 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH91515.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH91515.1; Type=Miscellaneous discrepancy; Note=Probable intron retention.; Evidence={ECO:0000305};

    Alternative splice isoforms for CEP78 Gene


neXtProt entry for CEP78 Gene

Proteomics data for CEP78 Gene at MOPED

Post-translational modifications for CEP78 Gene

  • Ubiquitination at Lys90, Lys317, and Lys374
  • Modification sites at PhosphoSitePlus

Other Protein References for CEP78 Gene

No data available for DME Specific Peptides for CEP78 Gene

Domains for CEP78 Gene

Protein Domains for CEP78 Gene


Suggested Antigen Peptide Sequences for CEP78 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CEP78 family.
  • Belongs to the CEP78 family.
genes like me logo Genes that share domains with CEP78: view

No data available for Gene Families for CEP78 Gene

Function for CEP78 Gene

Animal Model Products

miRNA for CEP78 Gene

miRTarBase miRNAs that target CEP78

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CEP78

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for CEP78 Gene

Localization for CEP78 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEP78 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.

Subcellular locations from

Jensen Localization Image for CEP78 Gene COMPARTMENTS Subcellular localization image for CEP78 gene
Compartment Confidence
cytoskeleton 5
cytosol 4
nucleus 2

Gene Ontology (GO) - Cellular Components for CEP78 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005813 centrosome IDA 21399614
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with CEP78: view

Pathways for CEP78 Gene

genes like me logo Genes that share pathways with CEP78: view

Gene Ontology (GO) - Biological Process for CEP78 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000086 G2/M transition of mitotic cell cycle TAS --
GO:0000278 mitotic cell cycle TAS --
GO:0006996 organelle organization TAS --
genes like me logo Genes that share ontologies with CEP78: view

Transcripts for CEP78 Gene

Unigene Clusters for CEP78 Gene

Centrosomal protein 78kDa:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CEP78

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CEP78 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b · 13c · 13d ^ 14a · 14b ^ 15 ^ 16a · 16b · 16c ·
SP1: - - - -
SP2: - - -
SP4: -
SP5: -
SP7: - - - - - - - - - - - - - - - - - - - - -

ExUns: 16d

Relevant External Links for CEP78 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CEP78 Gene

mRNA expression in normal human tissues for CEP78 Gene

Protein differential expression in normal tissues for CEP78 Gene

This gene is overexpressed in Testis (28.4), Peripheral blood mononuclear cells (23.5), and CD8 Tcells (11.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CEP78 Gene

SOURCE GeneReport for Unigene cluster for CEP78 Gene Hs.374421

genes like me logo Genes that share expressions with CEP78: view

Expression partners for CEP78 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CEP78 Gene

Orthologs for CEP78 Gene

This gene was present in the common ancestor of animals.

Orthologs for CEP78 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CEP78 35
  • 88.73 (n)
  • 85.73 (a)
CEP78 36
  • 75 (a)
(Canis familiaris)
Mammalia CEP78 35
  • 89.1 (n)
  • 87.4 (a)
CEP78 36
  • 77 (a)
(Mus musculus)
Mammalia Cep78 35
  • 81.53 (n)
  • 79.69 (a)
Cep78 16
Cep78 36
  • 71 (a)
(Pan troglodytes)
Mammalia CEP78 35
  • 99.35 (n)
  • 99.19 (a)
CEP78 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Cep78 35
  • 82.17 (n)
  • 79.23 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 56 (a)
-- 36
  • 64 (a)
-- 36
  • 49 (a)
-- 36
  • 56 (a)
(Ornithorhynchus anatinus)
Mammalia CEP78 36
  • 53 (a)
(Gallus gallus)
Aves CEP78 35
  • 66.16 (n)
  • 63.04 (a)
CEP78 36
  • 50 (a)
(Anolis carolinensis)
Reptilia CEP78 36
  • 48 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cep78 35
  • 62.63 (n)
  • 60.71 (a)
Str.11363 35
(Danio rerio)
Actinopterygii cep78 35
  • 56.77 (n)
  • 53.38 (a)
cep78 36
  • 44 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.2778 35
fruit fly
(Drosophila melanogaster)
Insecta CG7886 36
  • 18 (a)
Species with no ortholog for CEP78:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CEP78 Gene

Gene Tree for CEP78 (if available)
Gene Tree for CEP78 (if available)

Paralogs for CEP78 Gene

No data available for Paralogs for CEP78 Gene

Variants for CEP78 Gene

Sequence variations from dbSNP and Humsavar for CEP78 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs928390 -- 78,239,363(+) ATGCC(C/T)ACGCA intron-variant
rs966592 -- 78,235,677(+) GCCTC(C/T)GCCTC upstream-variant-2KB
rs1057650 -- 78,264,233(-) TCCAG(A/G)ATCAT reference, synonymous-codon
rs1065334 -- 78,266,855(+) AAATA(C/T)GTTTC utr-variant-3-prime, intron-variant
rs1571776 -- 78,239,585(-) TTTTA(C/T)CTCAC intron-variant

Relevant External Links for CEP78 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CEP78 Gene

Disorders for CEP78 Gene

No disorders were found for CEP78 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CEP78 Gene

Publications for CEP78 Gene

  1. Proteomic characterization of the human centrosome by protein correlation profiling. (PMID: 14654843) Andersen J.S. … Mann M. (Nature 2003) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. (PMID: 16462731) Petretti C. … Giet R. (EMBO Rep. 2006) 3
  5. Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach. (PMID: 18654987) Thalappilly S. … Dusetti N.J. (Proteomics 2008) 3

Products for CEP78 Gene

Sources for CEP78 Gene

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