CEP44 Gene
protein-coding GIFtS: 39
GCID: GC04P175205
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centrosomal protein 44kDa(Previous name: KIAA1712 )
(Previous symbol: KIAA1712)
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Aliases
for CEP44 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Centrosomal Protein 44kDa1 2 | | KIAA17121 2 3 | | PS1TP32 3 | | HBV PreS1-Transactivated Protein 32 3 | | Centrosomal Protein Of 44 KDa2 |
Export aliases for CEP44 gene to outside databases |
Summaries
for CEP44 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CEP44 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for CEP44
Other transcription factors
Search SABiosciences Chromatin IP Primers for CEP44
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEP44 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q34 Ensembl cytogenetic band: 4q34.1 HGNC cytogenetic band: 4q34CEP44 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P175205: view genomic region
(about GC identifiers)
Start:
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175,204,828 bp from pter |
End:
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175,254,531 bp from pter |
Size:
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49,704 bases |
Orientation:
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plus strand |
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Proteins
for CEP44 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CEP44_HUMAN, Q9C0F1 (See
protein sequence)Recommended Name: Centrosomal protein of 44 kDa Size: 390 amino acids; 44140 Da
Subcellular location: Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Midbody.Note=Localizes to centrosomes, spindle poles, and weakly in midbody
Sequence caution: Sequence=BAB21803.1; Type=Erroneous initiation;
Secondary accessions: A8K8W9 A8MW11 B3KT53 D3DP42 Q8IXZ4Alternative splicing: 2 isoforms: Q9C0F1-1 Q9C0F1-2 Explore the universe of human proteins at neXtProt for CEP44: NX_Q9C0F1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9C0F1
CEP44 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001035247.1 NP_001138786.1
ENSEMBL proteins: ENSP00000423153 ENSP00000427337 ENSP00000389427 ENSP00000380009 ENSP00000423949 ENSP00000421128 ENSP00000423922 ENSP00000408221 ENSP00000296519
Human Recombinant Protein Products for CEP44:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CEP44 for ontologies About GeneDecksing
CEP44 Antibody Products:
Assay Products for CEP44: |
Protein
Domains /
Families
for CEP44 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9C0F1 |
Function
for CEP44 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEP44 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEP44 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for CEP44 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CEP44 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEP44 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP44 |
|
Pathways & Interactions
for CEP44 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CEP44
STRING Interaction
Network Preview (showing 5 interactants - click image to see 9)
5/13 Interacting proteins for CEP44 (Q9C0F12, 3 ENSP000003894274) via UniProtKB, MINT, STRING, and/or I2D (see all 13)About this table
|
Drugs & Compounds
for CEP44 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CEP44
Search CenterWatch for drugs/clinical trials and news about CEP44
|
Transcripts
for CEP44 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CEP44 gene (3 alternative transcripts): NM_030633.1 NM_001040157.2 NM_001145314.1 Unigene Cluster for CEP44: Centrosomal protein 44kDa Hs.555989 [show with all ESTs]Unigene Representative Sequence: NM_00104015710 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000503780(uc003itr.3) ENST00000505124 ENST00000457424(uc010iro.2)
ENST00000396791(uc003its.2) ENST00000514712 ENST00000515299 ENST00000503053
ENST00000508483 ENST00000426172 ENST00000296519
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEP44 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEP44 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for CEP44 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CEP44 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEP44 |
Additional cDNA sequence: AB051499.1 AK094961.1 AK292484.1 AY426674.1 BC045590.1 8 DOTS entries: DT.100766227 DT.203688 DT.95168039 DT.100776394 DT.95156583 DT.121271509 DT.121271473 DT.121271508 24/113 AceView cDNA sequences (see all 113): CD251823 CB215492 BX486511 AK094961 AI149345 BC038667 H54701 BQ574424 AY426674 AA256025 BX471733 BI551792 W92618 NM_030633 AA255930 AI093478 AI628371 BU753459 AA783020 AW952351 AI633734 BQ438261 CB857864 BX409693
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for CEP44 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b |
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| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CEP44
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Expression
for CEP44 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CEP44 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGCTTGTT
About this image
See CEP44 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CEP44
SOURCE GeneReport for Unigene cluster: Hs.555989
SABiosciences Custom PCR Arrays for CEP44
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CEP44
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CEP44 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEP44 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEP44 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP44 |
Orthologs
for CEP44 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CEP44 gene from 5/18 species (see all 18) About this table
ENSEMBL Gene Tree for CEP44 (if available)
TreeFam Gene Tree for CEP44 (if available) |
Paralogs
for CEP44 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CEP44 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CEP44 (175204828 - 175254531 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CEP44: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CEP44 |
|
Disorders
/ Diseases
for CEP44 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CEP44 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CEP44 gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with CEP44) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. (PubMed id 21399614)1, 2, 3 Jakobsen L.... Andersen J.S. (2011)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
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External Searches for CEP44 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing CEP44 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CEP44 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing CEP44 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CEP44 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for CEP44 gene:
Search GeneIP for patents involving CEP44
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CEP44 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CEP44 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CEP44 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CEP44 | | | OriGene Protein Over-expression Lysate for CEP44 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CEP44 | | OriGene 3'-UTR Clone for CEP44 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEP44 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEP44 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CEP44 | | OriGene Custom Protein Services for CEP44 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CEP44 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CEP44 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEP44 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEP44 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEP44 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEP44 |
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 |  |  |  | |
| | | | Search Tocris compounds for CEP44 |
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 | | | CEP44 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP44 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for CEP44 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEP44 |
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