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CEP350 Gene

protein-coding   GIFtS: 54
GCID: GC01P179923

Centrosomal Protein 350kDa

  Search for CEP350
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Centrosomal Protein 350kDa1 2     Centrosome-Associated Protein 3502
CAP3502 3     Cep3503
Centrosome Associated Protein 3501     KIAA04803
GM1332     Centrosome-Associated Protein Of 350 KDa3

External Ids:    HGNC: 242381   Entrez Gene: 98572   Ensembl: ENSG000001358377   UniProtKB: Q5VT063   

Export aliases for CEP350 gene to outside databases

Previous GC identifers: GC01P178190 GC01P151155


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CEP350 Gene:
The product of this gene is a large protein with a CAP-Gly domain typically found in cytoskeleton-associated
proteins. The encoded protein primarily localizes to the centrosome, a non-membraneous organelle that functions
as the major microtubule-organizing center in animal cells. The encoded protein directly interacts with another
large centrosomal protein and is required to anchor microtubules at the centrosome. It is also implicated in the
regulation of a class of nuclear hormone receptors in the nucleus. Several alternatively spliced transcript
variants have been found, but their full-length nature has not been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for CEP350 Gene:
CEP350 (centrosomal protein 350kDa) is a protein-coding gene. An important paralog of this gene is CLIP2.

UniProtKB/Swiss-Prot: CE350_HUMAN, Q5VT06
Function: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least,
SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule
network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity

Gene Wiki entry for CEP350 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CEP350 gene promoter:
         STAT1   POU3F1   STAT1beta   Roaz   STAT1alpha   SRY   POU2F1   POU2F1a   TGIF   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCEP350 promoter sequence
   Search Chromatin IP Primers for CEP350

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEP350


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25.2   Ensembl cytogenetic band:  1q25.2   HGNC cytogenetic band: 1q25.2

CEP350 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEP350 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P179923:  view genomic region     (about GC identifiers)

Start:
179,923,873 bp from pter      End:
180,084,015 bp from pter
Size:
160,143 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CE350_HUMAN, Q5VT06 (See protein sequence)
Recommended Name: Centrosome-associated protein 350  
Size: 3117 amino acids; 350930 Da
Subunit: Part of a ternary complex composed of SASS6, CENPJ and CEP350. Part of a ternary complex that contains
CEP350, FGFR1OP and MAPRE1. Interacts directly with FGFR1OP via its C-terminus. Interacts with NR1H3, PPARA,
PPARD and PPARG. Interacts directly with microtubules. Interacts with the fusion protein FGFR1OP-FGFR1, and by
doing so recruits and activates PI3K and PLC-gamma
1 PDB 3D structure from and Proteopedia for CEP350:
2COZ (3D)    
Secondary accessions: O75068 Q8TDK3 Q8WY20

Explore the universe of human proteins at neXtProt for CEP350: NX_Q5VT06

Explore proteomics data for CEP350 at MOPED

Post-translational modifications: 

  • Phosphorylated during mitosis1
  • Ubiquitination2 at Lys250, Lys663, Lys686, Lys829, Lys1318
  • Modification sites at PhosphoSitePlus

  • See CEP350 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055625.4  
    ENSEMBL proteins: 
     ENSP00000356579   ENSP00000435808   ENSP00000350016   ENSP00000407044   ENSP00000432910  
     ENSP00000412460   ENSP00000409395   ENSP00000401608  

    CEP350 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CEP350

     
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    CEP350 Antibody Products:

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    Abcam antibodies for CEP350
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    LSBio Antibodies in human, mouse, rat for CEP350

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    Cloud-Clone Corp. CLIAs for CEP350
    Search eBioscience for ELISAs for CEP350 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR000938 CAP-Gly_domain
     IPR028750 CEP350

    Graphical View of Domain Structure for InterPro Entry Q5VT06

    ProtoNet protein and cluster: Q5VT06

    1 Blocks protein domain: IPB000938 CAP-Gly domain

    UniProtKB/Swiss-Prot: CE350_HUMAN, Q5VT06
    Similarity: Contains 1 CAP-Gly domain


    Find genes that share domains with CEP350           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CE350_HUMAN, Q5VT06
    Function: Plays an essential role in centriole growth by stabilizing a procentriolar seed composed of at least,
    SASS6 and CENPJ. Required for anchoring microtubules to the centrosomes and for the integrity of the microtubule
    network. Recruits PPARA to discrete subcellular compartments and thereby modulates PPARA activity

    Animal Models:

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CEP350
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CEP350

    miRNA
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    miRTarBase miRNAs that target CEP350:
    hsa-mir-1229-3p (MIRT036285), hsa-mir-19b-3p (MIRT031197)

    Block miRNA regulation of human, mouse, rat CEP350 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CEP350 (see all 148):
    hsa-miR-26a-2* hsa-miR-520f hsa-miR-3916 hsa-miR-298 hsa-miR-1243 hsa-miR-3116 hsa-miR-3170 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidCEP350 3' UTR sequence
    Inhib. RNA
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    Addgene plasmids for CEP350 

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CE350_HUMAN, Q5VT06: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton,
    spindle. Nucleus. Note=Associated with mitotic spindles. Nuclear, in discrete foci. Associated with intermediate
    filaments. Also present in the pericentrosomal area
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    nucleus5
    cytosol3

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005813centrosome IDA--
    GO:0005819spindle IEA--

    Find genes that share ontologies with CEP350           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CEP350
    Interactions:

        Search GeneGlobe Interaction Network for CEP350

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CEP350 (Q5VT062, 3 ENSP000003565794) via UniProtKB, MINT, STRING, and/or I2D (see all 76)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APTXQ7Z2E32, 3, ENSP000004008064MINT-2867693 I2D: score=3 STRING: ENSP00000400806
    PLEKHA5Q9HAU03, ENSP000002992754I2D: score=3 STRING: ENSP00000299275
    FGFR1OPO956843, ENSP000003558124I2D: score=1 STRING: ENSP00000355812
    PPP2R1AP301533, ENSP000003248044I2D: score=1 STRING: ENSP00000324804
    PPP2CAP677753, ENSP000004184474I2D: score=1 STRING: ENSP00000418447
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CEP350 (CE350)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CEP350 gene: 
    NM_014810.4  

    Unigene Cluster for CEP350:

    Centrosomal protein 350kDa
    Hs.413045  [show with all ESTs]
    Unigene Representative Sequence: NM_014810
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367607(uc001gnr.1 uc001gnu.3 uc009wxl.2 uc001gnt.3 uc001gnv.3)
    ENST00000491495 ENST00000357434 ENST00000418229 ENST00000490047 ENST00000429851(uc001gnx.1)
    ENST00000437245 ENST00000484356 ENST00000490141(uc001gnw.1) ENST00000417046
    ENST00000496440
    miRNA
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    Block miRNA regulation of human, mouse, rat CEP350 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CEP350 (see all 148):
    hsa-miR-26a-2* hsa-miR-520f hsa-miR-3916 hsa-miR-298 hsa-miR-1243 hsa-miR-3116 hsa-miR-3170 hsa-miR-200b
    SwitchGear 3'UTR luciferase reporter plasmidCEP350 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CEP350
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CEP350 (NM_014810)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEP350
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEP350
    Addgene plasmids for CEP350 
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CEP350
      QuantiTect SYBR Green Assays in human, mouse, rat CEP350
      QuantiFast Probe-based Assays in human, mouse, rat CEP350

    Additional mRNA sequence: 

    AF287356.1 AF387614.1 AK000704.1 AK022813.1 AK026986.1 AK095601.1 AK126046.1 AY007149.1 
    BC017847.1 BC033619.1 BC048310.1 

    16 DOTS entries:

    DT.97800064  DT.95272385  DT.86851491  DT.100785420  DT.97846592  DT.97763283  DT.101970237  DT.121417667 
    DT.95086619  DT.100785417  DT.114455  DT.86859778  DT.91641603  DT.97846595  DT.121417692  DT.95272384 

    Selected AceView cDNA sequences (see all 291):

    BI492583 AI685358 BX479502 AA778059 BQ574614 AI827427 BU171333 BQ788065 
    BC017847 AA664373 BM693887 BP369261 BM984904 BU740024 BU192534 AI656399 
    AI123066 BQ772066 NM_014810 BE856706 AF387614 AA731014 AW614160 AW504850 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CEP350 (see all 11)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^
    SP1:                                                                                                                                                            
    SP2:                                                              -     -     -     -     -     -     -     -     -                                             
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:              -                 -     -                                                                                                                     

    ExUns: 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33a · 33b ^ 34a · 34b · 34c · 34d ^ 35 ^ 36 ^ 37 ^ 38 ^ 39 ^ 40 ^
    SP1:                                                              -                                   -     -     -     -     -                             -   
    SP2:                                                              -                                                                                             
    SP3:                                                                                                  -     -     -     -     -                             -   
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 41 ^ 42 ^ 43 ^ 44 ^ 45
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for CEP350

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CEP350 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATACCTGTG
    CEP350 Expression
    About this image


    CEP350 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    CEP350 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CEP350 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.413045

    UniProtKB/Swiss-Prot: CE350_HUMAN, Q5VT06
    Tissue specificity: Detected in heart, brain, skeletal muscle, testis, placenta, lung, liver, kidney and pancreas

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP350

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CEP350 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cep3501 , 5 centrosomal protein 3501, 5 83.4(n)1
    80.73(a)1
      1 (67.64 cM)5
    740811  NM_001039184.11  NP_001034273.11 
     1558449665 
    chicken
    (Gallus gallus)
    Aves CEP3501 centrosomal protein 350kDa 68.9(n)
    65.25(a)
      424417  XM_422260.4  XP_422260.4 
    lizard
    (Anolis carolinensis)
    Reptilia CEP3506
    centrosomal protein 350kDa
    59(a)
    1 ↔ 1
    4(70532201-70622857)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cep3501 centrosomal protein 350kDa 56.88(n)
    51.3(a)
      100497540  XM_002936964.2  XP_002937010.2 
    zebrafish
    (Danio rerio)
    Actinopterygii BM860114.12   -- 74.32(n)   335035  BM860114.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes NIP1006
    Large subunit of the dynactin complex, which is in...
    22(a)
    1 → many
    XVI(220167-222773) YPL174C


    ENSEMBL Gene Tree for CEP350 (if available)
    TreeFam Gene Tree for CEP350 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CEP350 gene
    CLIP22  CLIP32  TBCB2  CLIP42  CLIP12  DCTN12  ENSG000002643242  
    3 SIMAP similar genes for CEP350 using alignment to 10 protein entries:     CE350_HUMAN (see all proteins):
    KIAA0480    FAM138C    DCTN1

    Find genes that share paralogs with CEP350           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CEP350 (see all 3140)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs718358031,2
    C--151205806(+) TTCTT-/TCTTTCT 1 -- int10--------
    rs558655341,2
    C--151231125(+) TATAT-/ATTTTAA 1 -- int11Minor allele frequency- AT:0.00NA 2
    rs1897307831,2
    --179922051(+) CTAGTA/TCAAAA 1 -- us2k10--------
    rs1831638421,2
    --179922375(+) TAGCTG/TTTTCA 1 -- us2k10--------
    rs2007727401,2
    C--179922409(+) CTTTC-/TTTTTT 1 -- us2k10--------
    rs1880450311,2
    --179922472(+) GGTGCA/GATCCC 1 -- us2k10--------
    rs1401866051,2
    --179922495(+) CCTCCA/GCCTCG 1 -- us2k10--------
    rs1917767891,2
    --179922534(+) CTCCCG/TAGTAG 1 -- us2k10--------
    rs1835651871,2
    C--179922589(+) TTTTTA/GGTAGA 1 -- us2k10--------
    rs1116338791,2
    C,F--179922641(+) TGACCC/TCGTGA 1 -- us2k12Minor allele frequency- T:0.50CSA 4

    HapMap Linkage Disequilibrium report for CEP350 (179923873 - 180084015 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CEP350:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv520322CNV Loss19592680
    nsv466228CNV Loss19166990
    nsv872573CNV Loss21882294
    nsv3755CNV Loss18451855
    nsv520278CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CEP350
    DNA2.0 Custom Variant and Variant Library Synthesis for CEP350

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with CEP350           About GenesLikeMe

    Genetic Association Database (GAD): CEP350
    Human Genome Epidemiology (HuGE) Navigator: CEP350 (1 document)

    Export disorders for CEP350 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CEP350 gene, integrated from 10 sources (see all 40):
    (articles sorted by number of sources associating them with CEP350)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A complex of two centrosomal proteins, CAP350 and FOP, cooperates with EB1 in microtubule anchoring. (PubMed id 16314388)1, 2, 3, 9 Yan X.... Nigg E.A. (Mol. Biol. Cell 2006)
    2. Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor alpha are altered by the centrosome- associated protein CAP350. (PubMed id 15615782)1, 2, 3 Patel H.... Capone J.P. (J. Cell Sci. 2005)
    3. Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex. (PubMed id 17878239)1, 2, 9 Hoppeler-Lebel A.... Tassin A.-M. (J. Cell Sci. 2007)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    7. Proteomic characterization of the human centrosome by protein correlation profiling. (PubMed id 14654843)1, 2 Andersen J.S....Mann M. (Nature 2003)
    8. Identification of six novel genes by experimental validation of GeneMachine predicted genes. (PubMed id 11891061)1, 2 Makalowska I.... Carpten J.D. (Gene 2002)
    9. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    10. Genetic variants associated with disordered eating. (PubMed id 23568457)1 Wade T.D....Martin N.G. (Int J Eat Disord 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9857 HGNC: 24238 AceView: CAP350 Ensembl:ENSG00000135837 euGenes: HUgn9857
    ECgene: CEP350 H-InvDB: CEP350

    (According to HUGE)
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    HUGE: KIAA0480

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CEP350 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CEP350 gene:
    Search GeneIP for patents involving CEP350

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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