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Aliases for CEP128 Gene

Aliases for CEP128 Gene

  • Centrosomal Protein 128kDa 2 3
  • C14orf145 3 4
  • C14orf61 3 4
  • Chromosome 14 Open Reading Frame 145 2
  • Chromosome 14 Open Reading Frame 61 2
  • Lens Epithelium-Derived Protein 3
  • Centrosomal Protein Of 128 KDa 3
  • LEDP/132 3
  • Cep128 4

External Ids for CEP128 Gene

Previous Symbols for CEP128 Gene

  • C14orf61
  • C14orf145

Summaries for CEP128 Gene

GeneCards Summary for CEP128 Gene

CEP128 (Centrosomal Protein 128kDa) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEP128 Gene

Genomics for CEP128 Gene

Genomic Location for CEP128 Gene

Start:
80,476,983 bp from pter
End:
80,959,517 bp from pter
Size:
482,535 bases
Orientation:
Minus strand

Genomic View for CEP128 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CEP128 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEP128 Gene

No data available for Regulatory Elements for CEP128 Gene

Proteins for CEP128 Gene

  • Protein details for CEP128 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZU80-CE128_HUMAN
    Recommended name:
    Centrosomal protein of 128 kDa
    Protein Accession:
    Q6ZU80
    Secondary Accessions:
    • B9EK52
    • Q86X97
    • Q96ML4

    Protein attributes for CEP128 Gene

    Size:
    1094 amino acids
    Molecular mass:
    128015 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB71273.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CEP128 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CEP128 Gene

Proteomics data for CEP128 Gene at MOPED

Post-translational modifications for CEP128 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys814 and Lys1064

No data available for DME Specific Peptides for CEP128 Gene

Domains for CEP128 Gene

Protein Domains for CEP128 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with CEP128: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CEP128 Gene

Function for CEP128 Gene

miRNA for CEP128 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for CEP128 Gene

Localization for CEP128 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEP128 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Note=Associates with the mother centriole.

Gene Ontology (GO) - Cellular Components for CEP128 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IDA 21399614
GO:0005737 cytoplasm IDA --
GO:0005814 centriole IDA 21399614
GO:0005815 microtubule organizing center IDA --
genes like me logo Genes that share ontologies with CEP128: view

Pathways for CEP128 Gene

SuperPathways for CEP128 Gene

No Data Available

Interacting Proteins for CEP128 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000281129%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000281129 for CEP128 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for CEP128 Gene

None

No data available for Pathways by source for CEP128 Gene

Transcripts for CEP128 Gene

mRNA/cDNA for CEP128 Gene

(9) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(16) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CEP128 Gene

Centrosomal protein 128kDa:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CEP128 Gene

No ASD Table

Relevant External Links for CEP128 Gene

GeneLoc Exon Structure for
CEP128
ECgene alternative splicing isoforms for
CEP128

Expression for CEP128 Gene

mRNA expression in normal human tissues for CEP128 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for CEP128 Gene

SOURCE GeneReport for Unigene cluster for CEP128 Gene Hs.162889

genes like me logo Genes that share expressions with CEP128: view

Orthologs for CEP128 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CEP128 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CEP128 36
  • 99.27 (n)
  • 98.54 (a)
CEP128 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 66 (a)
OneToMany
-- 37
  • 85 (a)
OneToMany
CEP128 36
  • 87.21 (n)
  • 85.74 (a)
dog
(Canis familiaris)
Mammalia CEP128 36
  • 88.32 (n)
  • 85.78 (a)
CEP128 37
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cep128 36
  • 81.24 (n)
  • 78.83 (a)
Cep128 16
Cep128 37
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CEP128 37
  • 55 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CEP128 37
  • 57 (a)
OneToOne
chicken
(Gallus gallus)
Aves CEP128 36
  • 65.77 (n)
  • 56.9 (a)
CEP128 37
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CEP128 37
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cep128 36
  • 57.39 (n)
  • 48.38 (a)
zebrafish
(Danio rerio)
Actinopterygii cep128 36
  • 52.59 (n)
  • 40.88 (a)
cep128 37
  • 39 (a)
OneToOne
Species with no ortholog for CEP128:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CEP128 Gene

ENSEMBL:
Gene Tree for CEP128 (if available)
TreeFam:
Gene Tree for CEP128 (if available)

Paralogs for CEP128 Gene

genes like me logo Genes that share paralogs with CEP128: view

No data available for Paralogs for CEP128 Gene

Variants for CEP128 Gene

Sequence variations from dbSNP and Humsavar for CEP128 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs17519 -- 80,621,550(+) AAAAC(A/G)TCATA intron-variant
rs149626 -- 80,801,459(-) taaaa(A/T)tcagc intron-variant
rs150997 -- 80,801,789(-) ctggg(A/G)ctaca intron-variant
rs162104 -- 80,796,473(-) aggaa(A/T)ttttt intron-variant
rs162171 -- 80,794,033(-) GAGGG(G/T)CAGCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CEP128 Gene

Variant ID Type Subtype PubMed ID
nsv902116 CNV Loss 21882294
esv1363737 CNV Insertion 17803354
esv2433413 CNV Deletion 19546169
esv2515564 CNV Deletion 19546169
nsv832840 CNV Gain 17160897
esv2748924 CNV Deletion 23290073
esv2657436 CNV Deletion 23128226
nsv456346 CNV Loss 19166990

Relevant External Links for CEP128 Gene

HapMap Linkage Disequilibrium report
CEP128

Disorders for CEP128 Gene

No disorders were found for CEP128 Gene.

No data available for UniProtKB/Swiss-Prot for CEP128 Gene

Publications for CEP128 Gene

  1. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. (PMID: 21399614) Jakobsen L. … Andersen J.S. (EMBO J. 2011) 2 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for CEP128 Gene

  • antibodies-online peptides for CEP128
  • antibodies-online antibodies for CEP128
  • antibodies-online kits for CEP128

Sources for CEP128 Gene

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