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Aliases for CEP128 Gene

Aliases for CEP128 Gene

  • Centrosomal Protein 128 2 3
  • Centrosomal Protein 128kDa 2 3 5
  • C14orf145 3 4
  • C14orf61 3 4
  • Chromosome 14 Open Reading Frame 145 2
  • Chromosome 14 Open Reading Frame 61 2
  • Lens Epithelium-Derived Protein 3
  • LEDP/132 3
  • Cep128 4

External Ids for CEP128 Gene

Previous HGNC Symbols for CEP128 Gene

  • C14orf61
  • C14orf145

Previous GeneCards Identifiers for CEP128 Gene

  • GC14M080963

Summaries for CEP128 Gene

GeneCards Summary for CEP128 Gene

CEP128 (Centrosomal Protein 128) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEP128 Gene

Genomics for CEP128 Gene

Regulatory Elements for CEP128 Gene

Enhancers for CEP128 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CEP128 on UCSC Golden Path with GeneCards custom track

Genomic Location for CEP128 Gene

80,476,983 bp from pter
80,959,517 bp from pter
482,535 bases
Minus strand

Genomic View for CEP128 Gene

Genes around CEP128 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CEP128 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CEP128 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEP128 Gene

Proteins for CEP128 Gene

  • Protein details for CEP128 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Centrosomal protein of 128 kDa
    Protein Accession:
    Secondary Accessions:
    • B9EK52
    • Q86X97
    • Q96ML4

    Protein attributes for CEP128 Gene

    1094 amino acids
    Molecular mass:
    128015 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB71273.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for CEP128 Gene


neXtProt entry for CEP128 Gene

Proteomics data for CEP128 Gene at MOPED

Post-translational modifications for CEP128 Gene

  • Ubiquitination at Lys 814 and Lys 1064
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CEP128 Gene

Domains & Families for CEP128 Gene

Protein Domains for CEP128 Gene


Suggested Antigen Peptide Sequences for CEP128 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CEP128: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CEP128 Gene

Function for CEP128 Gene

genes like me logo Genes that share phenotypes with CEP128: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CEP128 Gene

Localization for CEP128 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEP128 Gene

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Note=Associates with the mother centriole.

Subcellular locations from

Jensen Localization Image for CEP128 Gene COMPARTMENTS Subcellular localization image for CEP128 gene
Compartment Confidence
cytoskeleton 5
cytosol 3
nucleus 3
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for CEP128 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IDA 21399614
GO:0005737 cytoplasm IDA --
GO:0005814 centriole IDA 21399614
genes like me logo Genes that share ontologies with CEP128: view

Pathways & Interactions for CEP128 Gene

SuperPathways for CEP128 Gene

No Data Available

Interacting Proteins for CEP128 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000281129 for CEP128 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for CEP128 Gene


No data available for Pathways by source and SIGNOR curated interactions for CEP128 Gene

Drugs & Compounds for CEP128 Gene

No Compound Related Data Available

Transcripts for CEP128 Gene

mRNA/cDNA for CEP128 Gene

(9) REFSEQ mRNAs :
(9) Additional mRNA sequences :
(16) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CEP128 Gene

Centrosomal protein 128kDa:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CEP128 Gene

No ASD Table

Relevant External Links for CEP128 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CEP128 Gene

mRNA expression in normal human tissues for CEP128 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CEP128 Gene

This gene is overexpressed in Plasma (58.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CEP128 Gene

SOURCE GeneReport for Unigene cluster for CEP128 Gene Hs.162889

genes like me logo Genes that share expression patterns with CEP128: view

Protein tissue co-expression partners for CEP128 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CEP128 Gene

Orthologs for CEP128 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CEP128 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CEP128 35
  • 87.21 (n)
  • 85.74 (a)
-- 36
  • 66 (a)
-- 36
  • 85 (a)
(Canis familiaris)
Mammalia CEP128 35
  • 88.32 (n)
  • 85.78 (a)
CEP128 36
  • 80 (a)
(Mus musculus)
Mammalia Cep128 35
  • 81.24 (n)
  • 78.83 (a)
Cep128 16
Cep128 36
  • 78 (a)
(Pan troglodytes)
Mammalia CEP128 35
  • 99.27 (n)
  • 98.54 (a)
CEP128 36
  • 99 (a)
(Monodelphis domestica)
Mammalia CEP128 36
  • 55 (a)
(Ornithorhynchus anatinus)
Mammalia CEP128 36
  • 57 (a)
(Gallus gallus)
Aves CEP128 35
  • 65.77 (n)
  • 56.9 (a)
CEP128 36
  • 58 (a)
(Anolis carolinensis)
Reptilia CEP128 36
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cep128 35
  • 57.39 (n)
  • 48.38 (a)
(Danio rerio)
Actinopterygii cep128 35
  • 52.59 (n)
  • 40.88 (a)
cep128 36
  • 39 (a)
Species with no ortholog for CEP128:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CEP128 Gene

Gene Tree for CEP128 (if available)
Gene Tree for CEP128 (if available)

Paralogs for CEP128 Gene

genes like me logo Genes that share paralogs with CEP128: view

No data available for Paralogs for CEP128 Gene

Variants for CEP128 Gene

Sequence variations from dbSNP and Humsavar for CEP128 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs7160694 - 80,916,501(+) TCAAT(A/C/T)GGTCA reference, missense
rs327463 - 80,784,911(+) TGATA(C/G/T)GATTC intron-variant, reference, missense
rs17519 -- 80,621,550(+) AAAAC(A/G)TCATA intron-variant
rs149626 -- 80,801,459(-) taaaa(A/T)tcagc intron-variant
rs150997 -- 80,801,789(-) ctggg(A/G/T)ctaca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CEP128 Gene

Variant ID Type Subtype PubMed ID
nsv902116 CNV Loss 21882294
esv1363737 CNV Insertion 17803354
esv2433413 CNV Deletion 19546169
esv2515564 CNV Deletion 19546169
nsv832840 CNV Gain 17160897
esv2748924 CNV Deletion 23290073
esv2657436 CNV Deletion 23128226
nsv456346 CNV Loss 19166990

Variation tolerance for CEP128 Gene

Residual Variation Intolerance Score: 29% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.65; 91.39% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CEP128 Gene

Disorders for CEP128 Gene

Relevant External Links for CEP128

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CEP128 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CEP128 Gene

Publications for CEP128 Gene

  1. Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods. (PMID: 21399614) Jakobsen L. … Andersen J.S. (EMBO J. 2011) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  4. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3
  5. Proximity Interactions among Centrosome Components Identify Regulators of Centriole Duplication. (PMID: 24613305) Firat-Karalar E.N. … Stearns T. (Curr. Biol. 2014) 3

Products for CEP128 Gene

Sources for CEP128 Gene