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CEP120 Gene

protein-coding   GIFtS: 50
GCID: GC05M122708

Centrosomal Protein 120kDa

(Previous name: coiled-coil domain containing 100)
(Previous symbol: CCDC100)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Centrosomal Protein 120kDa1 2
CCDC1001 2 3 5
Coiled-Coil Domain Containing 1001 2
Coiled-Coil Domain-Containing Protein 1002 3
Centrosomal Protein Of 120 KDa2
Cep1203

External Ids:    HGNC: 266901   Entrez Gene: 1532412   Ensembl: ENSG000001689447   OMIM: 6134465   UniProtKB: Q8N9603   

Export aliases for CEP120 gene to outside databases

Previous GC identifer: GC05M117868


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CEP120 Gene:
This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the
centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a
characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal.
Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple
transcript variants. (provided by RefSeq, Oct 2009)

GeneCards Summary for CEP120 Gene:
CEP120 (centrosomal protein 120kDa) is a protein-coding gene. Diseases associated with CEP120 include obesity, and cerebritis. GO annotations related to this gene include protein C-terminus binding.

UniProtKB/Swiss-Prot: CE120_HUMAN, Q8N960
Function: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the
processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for
proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of
neural progenitors. May play a role in centriole duplication during mitosis (By similarity)

Gene Wiki entry for CEP120 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000005.10  NT_034772.7  NC_018916.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CEP120 gene promoter:
         AML1a   FOXO3   Olf-1   CUTL1   Tal-1beta   E4BP4   AP-2gamma   FOXO3b   FOXO3a   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCEP120 promoter sequence
   Search Chromatin IP Primers for CEP120

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEP120


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q23.2   Ensembl cytogenetic band:  5q23.2   HGNC cytogenetic band: 5q23.2

CEP120 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEP120 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M122708:  view genomic region     (about GC identifiers)

Start:
122,680,579 bp from pter      End:
122,759,286 bp from pter
Size:
78,708 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CE120_HUMAN, Q8N960 (See protein sequence)
Recommended Name: Centrosomal protein of 120 kDa  
Size: 986 amino acids; 112640 Da
Subunit: Interacts with TACC2 and TACC3 (By similarity). Interacts with CCDC52 (By similarity)
Sequence caution: Sequence=BAC04155.1; Type=Erroneous initiation; Sequence=CAH10561.1; Type=Erroneous initiation;
Secondary accessions: Q6AI52 Q6AW89 Q8IWB5 Q8N9Y0 Q8NDE8
Alternative splicing: 3 isoforms:  Q8N960-1   Q8N960-2   Q8N960-3   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CEP120: NX_Q8N960

Explore proteomics data for CEP120 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys799
  • Modification sites at PhosphoSitePlus

  • See CEP120 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001159698.1  NP_694955.2  

    ENSEMBL proteins: 
     ENSP00000303058   ENSP00000422234   ENSP00000422089   ENSP00000421620   ENSP00000422382  
     ENSP00000428303   ENSP00000327504   ENSP00000307419   ENSP00000378819  

    CEP120 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for CEP120

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    Cloud-Clone Corp. CLIAs for CEP120


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR022136 DUF3668
     IPR000008 C2_dom

    Graphical View of Domain Structure for InterPro Entry Q8N960

    ProtoNet protein and cluster: Q8N960

    UniProtKB/Swiss-Prot: CE120_HUMAN, Q8N960
    Similarity: Belongs to the CEP120 family


    CEP120 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CE120_HUMAN, Q8N960
    Function: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the
    processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for
    proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of
    neural progenitors. May play a role in centriole duplication during mitosis (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008022protein C-terminus binding IEA--
         
    CEP120 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CEP120:
     Increased G1 DNA content  Increased cell size 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CEP120
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CEP120
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CEP120

    miRNA
    Products:
        
    miRTarBase miRNAs that target CEP120:
    hsa-mir-196a-5p (MIRT026036), hsa-let-7d-5p (MIRT032139), hsa-mir-20a-5p (MIRT050547)

    Block miRNA regulation of human, mouse, rat CEP120 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CEP120 (see all 41):
    hsa-miR-548j hsa-let-7d hsa-miR-106a hsa-miR-200a hsa-miR-301a hsa-miR-519a hsa-miR-141 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidCEP120 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CEP120

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CEP120

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP120


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CE120_HUMAN, Q8N960: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome (By similarity).
    Note=Regulates the localization of TACC3 to the centrosome in neural progenitors in vivo (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol2
    nucleus2
    endoplasmic reticulum1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005813centrosome IDA--

    CEP120 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CEP120
    Interactions:

        Search GeneGlobe Interaction Network for CEP120

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for CEP120 (Q8N9602 ENSP000003030584) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    STAT3ENSP000002646574STRING: ENSP00000264657
    --Q9WMX22MINT-7050039
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization ----
    GO:0008283cell proliferation ----
    GO:0021987cerebral cortex development IEA--
    GO:0022008neurogenesis IEA--
    GO:0022027interkinetic nuclear migration IEA--

    CEP120 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CEP120 (CE120)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CEP120 gene (2 alternative transcripts): 
    NM_001166226.1  NM_153223.3  

    Unigene Cluster for CEP120:

    Centrosomal protein 120kDa
    Hs.483209  [show with all ESTs]
    Unigene Representative Sequence: NM_153223
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000306467 ENST00000508138(uc011cwq.2) ENST00000513565 ENST00000508442
    ENST00000503049 ENST00000510582 ENST00000515110 ENST00000328236(uc003ktk.3)
    ENST00000306481(uc010jcz.2) ENST00000395431
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CEP120 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CEP120 (see all 41):
    hsa-miR-548j hsa-let-7d hsa-miR-106a hsa-miR-200a hsa-miR-301a hsa-miR-519a hsa-miR-141 hsa-let-7g
    SwitchGear 3'UTR luciferase reporter plasmidCEP120 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CEP120
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    OriGene ORF clones in mouse, rat for CEP120
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CEP120 (NM_153223)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEP120
    Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CEP120
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for CEP120
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CEP120
      QuantiTect SYBR Green Assays in human, mouse, rat CEP120
      QuantiFast Probe-based Assays in human, mouse, rat CEP120

    Additional mRNA sequence: 

    AK093409.1 AK095646.1 AK296999.1 AL833929.1 BC144558.1 BX648687.1 CR627324.1 

    5 DOTS entries:

    DT.442659  DT.91846411  DT.91650668  DT.87015883  DT.95134807 

    Selected AceView cDNA sequences (see all 83):

    BU623019 AI369071 BX280587 AA608634 AX748108 BX648687 BM803745 AA490782 
    AW188053 N62363 NM_153223 AA283676 AK093409 AA290905 AA810982 AI684272 
    AA731085 AW237459 AA861051 AK095646 AA364850 CR627324 H99380 AI377653 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CEP120    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b
    SP1:                                                                                                                                                
    SP2:                                                              -                                                           -                     


    ECgene alternative splicing isoforms for CEP120

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CEP120 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAACAGACA
    CEP120 Expression
    About this image


    CEP120 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Eye (Sensory Organs)
             Retina
    CEP120 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CEP120 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.483209
        Custom PCR Arrays for CEP120
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEP120

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CEP120 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cep1201 , 5 centrosomal protein 1201, 5 84.87(n)1
    89.85(a)1
      18 (29.07 cM)5
    2255231  NM_178686.31  NP_848801.21 
     536817245 
    chicken
    (Gallus gallus)
    Aves CEP1201 centrosomal protein 120kDa 73.42(n)
    73.9(a)
      426802  XM_424414.4  XP_424414.4 
    lizard
    (Anolis carolinensis)
    Reptilia CEP1206
    centrosomal protein 120kDa
    72(a)
    1 ↔ 1
    GL343193.1(12540469-12572985)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.55542 Xenopus laevis transcribed sequences 76.94(n)    BX853747.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cep1201 centrosomal protein 120kDa 60.2(n)
    61.64(a)
      100334628  XM_002663045.3  XP_002663091.2 


    ENSEMBL Gene Tree for CEP120 (if available)
    TreeFam Gene Tree for CEP120 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CEP120 (see all 1706)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1881827441,2
    --122680138(+) ACATGG/TTATTA 2 -- ds50010--------
    rs1809053491,2
    --122680180(+) TGCAGG/TACATG 2 -- ds50010--------
    rs174728321,2
    C,F,H--122680189(+) TGCCCG/ACATTA 2 -- ds500128Minor allele frequency- A:0.27NA EA NS CSA WA 2982
    rs1443383151,2
    --122680266(+) TAAAAC/TATTTG 2 -- ds50010--------
    rs746580371,2
    C,F--122680370(+) CAAAAT/CCAGTG 2 -- ds50011Minor allele frequency- C:0.10WA 118
    rs68903761,2
    C,F,A,H--122680442(+) GTTAAG/TATTTC 2 -- ds500115Minor allele frequency- T:0.32NS EA NA WA CSA 790
    rs114361601,2
    C--122680580(+) AACTCA/-AGAGA 2 -- ut312Minor allele frequency- -:0.25NA CSA 4
    rs10474841,2
    C,F,H--122680667(-) TTCTAA/CAATGG 2 -- ut3117Minor allele frequency- C:0.14MN NS EA NA WA 2282
    rs746679441,2
    C,F--122680672(+) TTAGAA/GAAGTC 2 -- ut311Minor allele frequency- G:0.07EA 120
    rs1856603491,2
    --122680678(+) AAGTCA/CTTTTT 2 -- ut310--------

    HapMap Linkage Disequilibrium report for CEP120 (122680579 - 122759286 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for CEP120:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2730714CNV Deletion23290073
    esv2730716CNV Deletion23290073
    esv2183522CNV Deletion18987734
    esv2730715CNV Deletion23290073
    nsv4980CNV Insertion18451855
    nsv327517CNV Loss16902084
    nsv830472CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CEP120
    DNA2.0 Custom Variant and Variant Library Synthesis for CEP120

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613446    OMIM disorders: --

    3 diseases for CEP120:    
    About MalaCards
    obesity    cerebritis    neuronitis


    CEP120 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CEP120
    Human Genome Epidemiology (HuGE) Navigator: CEP120 (1 document)

    Export disorders for CEP120 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CEP120 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with CEP120)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. (PubMed id 19584346)1, 4 Vasan R.S....Blankenberg S. (JAMA 2009)
    2. Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. (PubMed id 19079260)1, 4 Thorleifsson G....Stefansson K. (Nat. Genet. 2009)
    3. Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. (PubMed id 17920017)1, 3 Xie Z....Tsai L.H. (Neuron 2007)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. CEP120 and SPICE1 cooperate with CPAP in centriole elongation. (PubMed id 23810536)1 Comartin D....Pelletier L. (Curr. Biol. 2013)
    6. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    7. CEP120 interacts with CPAP and positively regulates centriole elongation. (PubMed id 23857771)1 Lin Y.N....Tang T.K. (J. Cell Biol. 2013)
    8. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PubMed id 22589738)1 Fox C.S....Borecki I.B. (PLoS Genet. 2012)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 153241 HGNC: 26690 AceView: FLJ36090 Ensembl:ENSG00000168944 euGenes: HUgn153241
    ECgene: CEP120 H-InvDB: CEP120

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CEP120 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CEP120 gene:
    Search GeneIP for patents involving CEP120

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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