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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CENPT Gene

protein-coding   GIFtS: 52
GCID: GC16M067862

Centromere Protein T

(Previous name: chromosome 16 open reading frame 56)
(Previous symbol: C16orf56)
  Search for CENPT
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Centromere Protein T1 2
C16orf561 2 3
Interphase Centromere Complex Protein 222 3
CENP-T2 3
Chromosome 16 Open Reading Frame 561
ICEN223

External Ids:    HGNC: 257871   Entrez Gene: 801522   Ensembl: ENSG000001029017   OMIM: 6115105   UniProtKB: Q96BT33   

Export aliases for CENPT gene to outside databases

Previous GC identifers: GC16M066421 GC16M053735


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CENPT Gene:
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on
which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized
by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128).
CENPT is an additional factor required for centromere assembly (Foltz et al., 2006 (PubMed 16622419)).(supplied
by OMIM, Mar 2008)

GeneCards Summary for CENPT Gene: 
CENPT (centromere protein T) is a protein-coding gene. Among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include DNA binding and protein heterodimerization activity.

UniProtKB/Swiss-Prot: CENPT_HUMAN, Q96BT3
Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in
assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits
the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into
centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes
at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X
complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a
fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most
further proteins binding downstream. Required for normal chromosome organization and normal progress through
mitosis

Gene Wiki entry for CENPT Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CENPT gene promoter:
         ATF-2   NF-kappaB   GATA-2   AREB6   CRE-BP1   CBF-A   CBF-B   CP1A   NF-kappaB1   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCENPT promoter sequence
   Search SABiosciences Chromatin IP Primers for CENPT

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CENPT


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q22.1   Ensembl cytogenetic band:  16q22.1   HGNC cytogenetic band: 16q22.1

CENPT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CENPT gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M067862:  view genomic region     (about GC identifiers)

Start:
67,862,060 bp from pter      End:
67,881,714 bp from pter
Size:
19,655 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CENPT_HUMAN, Q96BT3 (See protein sequence)
Recommended Name: Centromere protein T  
Size: 561 amino acids; 60423 Da
Subunit: Component of the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and
MLF1IP/CENPU. The CENPA-NAC complex interacts with the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO,
CENPP, CENPQ, CENPR and CENPS. Part of a centromere complex consisting of CENPA, CENPT and CENPW. Part of a
centromere complex consisting of histone H3, CENPT and CENPW. Interacts (via N-terminus) with the NDC80 complex
(Probable). Component of a heterotetrameric CENP-T-W-S-X complex composed of APITD1/CENPS, STRA13/CENPX, CENPT
and CENPW. Interacts directly with CENPW. Binds DNA
Subcellular location: Nucleus. Chromosome, centromere, kinetochore. Note=Constitutively localizes to centromeres
throughout the cell cycle, and to kinetochores during mitosis. Localizes to the inner kinetochore, and may
connect it to the outer kinetochore via its N-terminus
Secondary accessions: Q96I29 Q96IC6 Q96NK9 Q9H901
Alternative splicing: 3 isoforms:  Q96BT3-1   Q96BT3-2   Q96BT3-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CENPT: NX_Q96BT3

Explore proteomics data for CENPT at MOPED 

Post-translational modifications:

  • UniProtKB: Dynamically phosphorylated at Ser-47 and probably also other sites during the cell cycle. Phosphorylated at Ser-47
    during G2 phase, metaphase and anaphase, but not during telophase or G1 phase
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96BT3

  • CENPT Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CENPT Protein Expression
    REFSEQ proteins: NP_079358.3  
    ENSEMBL proteins: 
     ENSP00000457810   ENSP00000461212   ENSP00000457294   ENSP00000457832   ENSP00000455918  
     ENSP00000457304   ENSP00000456714   ENSP00000454627   ENSP00000455801   ENSP00000454481  
     ENSP00000455638   ENSP00000460542   ENSP00000400140   ENSP00000219172   ENSP00000411594  
    Reactome Protein details: Q96BT3
    Human Recombinant Protein Products for CENPT: 
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    Novus Biologicals CENPT Protein
    Novus Biologicals CENPT Lysates
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    Cloud-Clone Corp. Proteins for CENPT 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000775chromosome, centromeric region IDA--
    GO:0000776kinetochore IDA--
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0005634nucleus IEA--
    GO:0005829cytosol TAS--

    CENPT for ontologies           About GeneDecksing



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    LSBio Antibodies in human, mouse, rat for CENPT 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR009072 Histone-fold

    Graphical View of Domain Structure for InterPro Entry Q96BT3

    ProtoNet protein and cluster: Q96BT3

    1 Blocks protein domain: IPB003958 Transcription factor CBF/NF-Y/archaeal histone

    UniProtKB/Swiss-Prot: CENPT_HUMAN, Q96BT3
    Domain: The largest part of the sequence forms an elongated and flexible stalk structure that is connected to a
    C-terminal globular domain with a histone-type fold (By similarity)
    Similarity: Belongs to the CENPT family


    CENPT for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CENPT_HUMAN, Q96BT3
    Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in
    assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits
    the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into
    centromeres. Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes
    at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X
    complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a
    fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most
    further proteins binding downstream. Required for normal chromosome organization and normal progress through
    mitosis

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0005515protein binding IPI19070575
    GO:0046982protein heterodimerization activity IEA--
         
    CENPT for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CENPT:
     Cell cycle / mitosis defect  Increased gamma-H2AX phosphory 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CENPT About                                                                                                See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    4DNA Damage
    Cell Cycle / Checkpoint Control0.32
    5Chromatin Regulation / Acetylation
    Chromatin Regulation / Acetylation

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Cell Signaling Technology (CST) Pathways for CENPT
        Chromatin Regulation / Acetylation
    Cell Cycle / Checkpoint Control

    5/9        Reactome Pathways for CENPT (see all 9)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Mitotic Anaphase
    Cell Cycle



    CENPT for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CENPT

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/77 Interacting proteins for CENPT (Q96BT32, 3 ENSP000002191724) via UniProtKB, MINT, STRING, and/or I2D (see all 77)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNCBQ161432, 3, ENSP000003080574MINT-64283 I2D: score=4 STRING: ENSP00000308057
    DHX29Q7Z4782, 3MINT-65178 I2D: score=5 
    PPCDCQ96CD22, 3, ENSP000003431904MINT-65179 I2D: score=4 STRING: ENSP00000343190
    TCEA2Q155603, ENSP000003435154I2D: score=4 STRING: ENSP00000343515
    CENPAP494503, ENSP000003368684I2D: score=1 STRING: ENSP00000336868
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0007059chromosome segregation IMP--
    GO:0007067mitosis IEA--
    GO:0051276chromosome organization IMP--
    GO:0051301cell division IEA--

    CENPT for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CENPT

    Search CenterWatch for drugs/clinical trials and news about CENPT

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CENPT gene: 
    NM_025082.3  

    Unigene Cluster for CENPT:

    Centromere protein T
    Hs.288382  [show with all ESTs]
    Unigene Representative Sequence: NM_025082
    18/36 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 36):
    ENST00000569862(uc010vkc.2 uc010vke.1) ENST00000562787(uc002eun.4)
    ENST00000562513 ENST00000436104 ENST00000565157 ENST00000568495 ENST00000574569
    ENST00000563885 ENST00000564817 ENST00000566758 ENST00000564128 ENST00000562947
    ENST00000562462 ENST00000565713 ENST00000568069 ENST00000564538 ENST00000566067
    ENST00000562338
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    Additional mRNA sequence: 

    AK056097.1 AK225399.1 AK291527.1 AK297570.1 AK300887.1 AK301621.1 BC007642.1 BC007864.2 
    BC015202.2 

    24/30 DOTS entries (see all 30):

    DT.456413  DT.95264015  DT.100828498  DT.120718391  DT.120718490  DT.120718357  DT.120718478  DT.91771873 
    DT.120718457  DT.91878330  DT.100828488  DT.91771871  DT.120718375  DT.120718440  DT.120718498  DT.95264032 
    DT.100828499  DT.102836977  DT.100828506  DT.120718359  DT.102836978  DT.120718345  DT.91964723  DT.100828500 

    24/333 AceView cDNA sequences (see all 333):

    AW007397 BP333862 F25139 AJ709255 T32225 CR613934 AW439290 BM922216 
    AW469249 CR594388 CR601879 AI186501 AA337412 CR594299 BM547429 CR619541 
    BU195633 BQ446572 BQ923780 AW958547 BU687818 BU944056 CR625684 BI833230 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for CENPT (see all 14)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10 ^ 11 ^ 12a · 12b ^
    SP1:                    -                                                           -     -           -                                                         
    SP2:                                                                                -     -           -                                                         
    SP3:                                                                                -     -     -     -                                                         
    SP4:                                                                                -                 -                                                         
    SP5:                                                                                -                 -                                                         

    ExUns: 13a · 13b · 13c ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17
    SP1:  -                                   -               
    SP2:                                      -               
    SP3:                                                      
    SP4:                                                      
    SP5:                                                      


    ECgene alternative splicing isoforms for CENPT

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CENPT expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGCCGCAA
    CENPT Expression
    About this image


    See CENPT Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CENPT

    SOURCE GeneReport for Unigene cluster: Hs.288382
        SABiosciences Custom PCR Arrays for CENPT
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CENPT gene from 4/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cenpt1 , 5 centromere protein T1, 5 72.38(n)1
    63.67(a)1
      8 (53.05 cM)5
    3203941  NM_177150.21  NP_796124.11 
     1058446785 
    chicken
    (Gallus gallus)
    Aves CENPT1 centromere protein T 48.02(n)
    36.86(a)
      415654  XM_414020.3  XP_414020.2 
    lizard
    (Anolis carolinensis)
    Reptilia CENPT6
    Uncharacterized protein
    64(a)
    1 ↔ 1
    GL343295.1(682555-683450)
    zebrafish
    (Danio rerio)
    Actinopterygii CENPT6
    centromere protein T
    15(a)
    1 ↔ 1
    21(6351085-6374255)


    ENSEMBL Gene Tree for CENPT (if available)
    TreeFam Gene Tree for CENPT (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/289 SNPs in CENPT are shown (see all 289)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2021532401,2
    --67862590(+) TCAAGA/CGCCTT 2 A syn10--------
    rs1881591381,2
    C--67862706(+) AGGGGC/GATGCC 2 P A mis10--------
    rs2022320951,2
    C--67862715(+) CCTGAA/CCAACA 2 V F mis10--------
    rs735938041,2
    C,F--67863064(+) TTCCCG/AATTCT 1 -- int13Minor allele frequency- A:0.04WA 122
    rs1929185851,2
    --67863239(+) TACCCA/GTAGGA 1 -- int10--------
    rs2014345511,2
    C--67863341(+) CAGGCA/GCTGGG 2 A V mis10--------
    rs118621351,2
    H--67863436(+) AAGGGG/TGGGGT 1 -- int10--------
    rs37437331,2
    C,F,A,H--67863451(+) GGGATT/CCCAGG 1 -- int130Minor allele frequency- C:0.41EA NS NA WA CSA 4253
    rs1852377111,2
    --67863513(+) TGGTGG/TGCCCC 1 -- int10--------
    rs1482235491,2
    --67863521(+) CCCACC/GTAGCT 1 -- int10--------

    HapMap Linkage Disequilibrium report for CENPT (67862060 - 67881714 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for CENPT:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv906813CNV Loss21882294
    nsv524363CNV Loss19592680
    nsv522852CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CENPT for disorders           About MalaCards
    OMIM gene information: 611510    OMIM disorders: --


    CENPT for disorders           About GeneDecksing


    Export disorders for CENPT gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CENPT gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with CENPT)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human CENP-A centromeric nucleosome-associated complex. (PubMed id 16622419)1, 2, 3 Foltz D.R....Cleveland D.W. (2006)
    2. Premitotic assembly of human CENPs -T and -W switches centromeric chromatin to a mitotic state. (PubMed id 21695110)1, 2 Prendergast L....Sullivan K.F. (2011)
    3. Cancer-upregulated gene 2 (CUG2), a new component of centromere complex, is required for kinetochore function. (PubMed id 19533040)1, 2 Kim H....Lee S. (2009)
    4. CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochore. (PubMed id 19070575)1, 2 Hori T....Fukagawa T. (2008)
    5. Live-cell imaging reveals sustained centromere binding of CENP-T via CENP-A and CENP-B. (PubMed id 19412974)1, 2 Hellwig D....Diekmann S. (2008)
    6. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. (PubMed id 16622420)1, 3 Okada M....Fukagawa T. (2006)
    7. Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. (PubMed id 16716197)1, 2 Izuta H.... Yoda K. (2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    10. CENP-T provides a structural platform for outer kineto chore assembly. (PubMed id 23334297)1 Nishino T....Fukagawa T. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80152 HGNC: 25787 AceView: FLJ13111 Ensembl:ENSG00000102901 euGenes: HUgn80152
    ECgene: CENPT H-InvDB: CENPT

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CENPT Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CENPT gene:
    Search GeneIP for patents involving CENPT

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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