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CENPP Gene

protein-coding   GIFtS: 47
GCID: GC09P095087

Centromere Protein P

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Centromere Protein P1 2
CENP-P2 3

External Ids:    HGNC: 329331   Entrez Gene: 4015412   Ensembl: ENSG000001883127   OMIM: 6115055   UniProtKB: Q6IPU03   

Export aliases for CENPP gene to outside databases

Previous GC identifers: GC09P094127 GC09P064765


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CENPP Gene:
CENPP is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA
(MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et
al., 2006 (PubMed 16622420)).(supplied by OMIM, Mar 2008)

GeneCards Summary for CENPP Gene:
CENPP (centromere protein P) is a protein-coding gene.

UniProtKB/Swiss-Prot: CENPP_HUMAN, Q6IPU0
Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is
involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in
incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the CENPP gene promoter:
         Nkx3-1   Nkx3-1 v4   GATA-3   Nkx3-1 v1   GATA-1   GATA-2   AREB6   Nkx3-1 v2   Nkx3-1 v3   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCENPP promoter sequence
   Search Chromatin IP Primers for CENPP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CENPP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.31   Ensembl cytogenetic band:  9q22.31   HGNC cytogenetic band: 9q22.31

CENPP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CENPP gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P095087:  view genomic region     (about GC identifiers)

Start:
95,087,741 bp from pter      End:
95,382,815 bp from pter
Size:
295,075 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CENPP_HUMAN, Q6IPU0 (See protein sequence)
Recommended Name: Centromere protein P  
Size: 288 amino acids; 33165 Da
Subunit: Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and
CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH,
CENPM, CENPN, CENPT and CENPU
Sequence caution: Sequence=CAI12591.1; Type=Erroneous gene model prediction; Sequence=CAI12592.1; Type=Erroneous
gene model prediction;
Secondary accessions: B3KS17 Q5T9F8 Q5T9F9

Explore the universe of human proteins at neXtProt for CENPP: NX_Q6IPU0

Explore proteomics data for CENPP at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys37
  • Modification sites at PhosphoSitePlus

  • See CENPP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001012267.1  NP_001273898.1  NP_001273900.1  

    ENSEMBL proteins: 
     ENSP00000364737   ENSP00000364729   ENSP00000364726  
    Reactome Protein details: Q6IPU0

    CENPP Human Recombinant Protein Products:

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    Novus Biologicals CENPP Proteins
    Novus Biologicals CENPP Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CENPP

     
    Search eBioscience for Proteins for CENPP 

     
    antibodies-online proteins for CENPP (4 products) 

     
    antibodies-online peptides for CENPP

    CENPP Antibody Products:

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    Cloud-Clone Corp. Antibodies for CENPP
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    antibodies-online antibodies for CENPP (23 products) 

    CENPP Assay Products:

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    Cloud-Clone Corp. ELISAs for CENPP
    Cloud-Clone Corp. CLIAs for CENPP
    Search eBioscience for ELISAs for CENPP 
    antibodies-online kits for CENPP (18 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR027801 CENP-P

    Graphical View of Domain Structure for InterPro Entry Q6IPU0

    ProtoNet protein and cluster: Q6IPU0


    Find genes that share domains with CENPP           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CENPP_HUMAN, Q6IPU0
    Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is
    involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in
    incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex

    Animal Models:

       genOway: Develop your customized and physiologically relevant rodent model for CENPP

    miRNA
    Products:
        
    miRTarBase miRNAs that target CENPP:
    hsa-let-7e-5p (MIRT051416)

    Block miRNA regulation of human, mouse, rat CENPP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CENPP (see all 43):
    hsa-miR-4328 hsa-miR-1260b hsa-let-7a-2* hsa-miR-3074-3p hsa-miR-219-5p hsa-miR-508-3p hsa-miR-1304 hsa-miR-3170
    SwitchGear 3'UTR luciferase reporter plasmidCENPP 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CENPP
    Predesigned siRNA for gene silencing in human, mouse, rat CENPP

    Gene Editing
    Products:
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    Clone
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    OriGene ORF clones in mouse, rat for CENPP
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    GenScript: all cDNA clones in your preferred vector: CENPP (NM_001012267)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CENPP

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CENPP 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CENPP


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CENPP_HUMAN, Q6IPU0: Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The
    CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    cytoskeleton1
    extracellular1
    lysosome1
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000775chromosome, centromeric region IEA--
    GO:0005654nucleoplasm TAS--
    GO:0005829cytosol TAS--

    Find genes that share ontologies with CENPP           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CENPP About    
    See pathways by source

    SuperPathContained pathways About
    1Mitotic Metaphase and Anaphase
    Mitotic Anaphase0.94
    Mitotic Metaphase and Anaphase0.93
    Separation of Sister Chromatids0.94
    2Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90
    3Packaging Of Telomere Ends
    Chromosome Maintenance0.62
    Deposition of New CENPA-containing Nucleosomes at the Centromere0.59
    Nucleosome assembly0.59
    4Mitotic Prometaphase
    Mitotic Prometaphase0.92
    Resolution of Sister Chromatid Cohesion0.92


    Find genes that share SuperPaths with CENPP           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4 Reactome Pathways for CENPP
        Resolution of Sister Chromatid Cohesion
    Mitotic Prometaphase
    Separation of Sister Chromatids
    Deposition of new CENPA-containing nucleosomes at the centromere


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CENPP
    Interactions:

        Search GeneGlobe Interaction Network for CENPP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CENPP (ENSP000003647374) via UniProtKB, MINT, STRING, and/or I2D (see all 80)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AURKBENSP000003139504STRING: ENSP00000313950
    BIRC5ENSP000003016334STRING: ENSP00000301633
    BUB1ENSP000003025304STRING: ENSP00000302530
    BUB1BENSP000002875984STRING: ENSP00000287598
    BUB3ENSP000003578584STRING: ENSP00000357858
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0006334nucleosome assembly TAS--
    GO:0034080CENP-A containing nucleosome assembly at centromere TAS--

    Find genes that share ontologies with CENPP           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CENPP



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CENPP gene (3 alternative transcripts): 
    NM_001012267.2  NM_001286969.1  NM_001286971.1  

    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000375587(uc004arz.3 uc010mqx.3) ENST00000375579(uc004asj.3)
    ENST00000375576
    miRNA
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    Block miRNA regulation of human, mouse, rat CENPP using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CENPP (see all 43):
    hsa-miR-4328 hsa-miR-1260b hsa-let-7a-2* hsa-miR-3074-3p hsa-miR-219-5p hsa-miR-508-3p hsa-miR-1304 hsa-miR-3170
    SwitchGear 3'UTR luciferase reporter plasmidCENPP 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for CENPP
    Predesigned siRNA for gene silencing in human, mouse, rat CENPP
    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CENPP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CENPP
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for CENPP
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CENPP
      QuantiTect SYBR Green Assays in human, mouse, rat CENPP
      QuantiFast Probe-based Assays in human, mouse, rat CENPP

    Selected AceView cDNA sequences (see all 50):

    AX747625 BM463624 AW117454 BX280699 AK091247 BM742274 AW503058 BM742743 
    AK092603 AX746874 BC071726 AL833701 CR592049 BU170470 CR597952 AW296701 
    AA748633 AA219624 BM709732 AL520331 BX537851 AA808317 AL520330 CF144300 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CENPP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CENPP Expression
    About this image


    CENPP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Ovary (Reproductive System)
             Primary Oocyte Primary Follicle
     
     Gonad
             Primary Oocyte Primary Follicle
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
    CENPP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CENPP Protein Expression
        Custom PCR Arrays for CENPP
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CENPP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CENPP gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cenpp1 , 5 centromere protein P1, 5 78.32(n)1
    67.83(a)1
      13 (25.27 cM)5
    663361  NM_025495.31  NP_079771.11 
     494640595 
    chicken
    (Gallus gallus)
    Aves CENPP1 centromere protein P 63.45(n)
    51.75(a)
      415952  NM_001044635.1  NP_001038100.1 
    lizard
    (Anolis carolinensis)
    Reptilia CENPP6
    centromere protein P
    41(a)
    1 ↔ 1
    2(156062409-156286636)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cenpp1 centromere protein P 55.31(n)
    44.07(a)
      101734622  XM_004913897.1  XP_004913954.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cenpp1 centromere protein P 54.5(n)
    46.56(a)
      445161  NM_001003555.2  NP_001003555.1 


    ENSEMBL Gene Tree for CENPP (if available)
    TreeFam Gene Tree for CENPP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CENPP gene
    1 SIMAP similar gene for CENPP using alignment to 2 protein entries:     CENPP_HUMAN (see all proteins):
    DKFZp779J2459

    Find genes that share paralogs with CENPP           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for CENPP
    PGOHUM00000263111 PGOHUM00000263242


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CENPP (see all 3126)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1382930651,2
    --95089879(+) AAAAGC/TTGAAG 1 -- int10--------
    rs1496165961,2
    C--95089914(+) CACAGA/GCCTTG 1 -- int10--------
    rs1443644301,2
    C--95090014(+) AGGGGA/GATCAG 1 -- int10--------
    rs753116091,2
    F--95090044(+) GAACTG/ACAATT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs1488020491,2
    C--95090162(+) CTGGCA/GTGGCC 1 -- int10--------
    rs1435726711,2
    --95090210(+) GAGTCC/TGTTCT 1 -- int10--------
    rs765894311,2
    C--95090226(+) TCTTAA/C/GGATCT 1 -- int10--------
    rs101168131,2
    C,F,A,H--95090360(+) GGTCCC/TCTTGA 1 -- int113Minor allele frequency- T:0.38NS EA NA WA CSA 788
    rs1928891811,2
    --95090369(+) GACCAA/GGAGGG 1 -- int10--------
    rs762471851,2
    C--95090373(+) AAGAGA/GGAGTC 1 -- int11Minor allele frequency- G:0.00CSA 1

    HapMap Linkage Disequilibrium report for CENPP (95087741 - 95337741 bp, first 250kb of CENPP)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CENPP:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2738772CNV Deletion23290073
    esv2658382CNV Deletion23128226
    esv1019101CNV Insertion17803354
    nsv527206CNV Loss19592680
    nsv893573CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CENPP
    DNA2.0 Custom Variant and Variant Library Synthesis for CENPP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 611505    OMIM disorders: --


    Find genes that share disorders with CENPP           About GenesLikeMe

    Genetic Association Database (GAD): CENPP
    Human Genome Epidemiology (HuGE) Navigator: CENPP (4 documents)

    Export disorders for CENPP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CENPP gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with CENPP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. (PubMed id 16622420)1, 2, 3 Okada M.... Fukagawa T. (Nat. Cell Biol. 2006)
    2. The human CENP-A centromeric nucleosome-associated complex. (PubMed id 16622419)1, 2, 3 Foltz D.R....Cleveland D.W. (Nat. Cell Biol. 2006)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex. (PubMed id 23028590)1 Eskat A....Diekmann S. (PLoS ONE 2012)
    9. Mammalian polo-like kinase 1-dependent regulation of the PBIP1-CENP-Q complex at kinetochores. (PubMed id 21454580)1 Kang Y.H....Lee K.S. (J. Biol. Chem. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 401541 HGNC: 32933 AceView: LOC401541 Ensembl:ENSG00000188312 euGenes: HUgn401541
    ECgene: CENPP H-InvDB: CENPP

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CENPP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CENPP gene:
    Search GeneIP for patents involving CENPP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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