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CENPM Gene

protein-coding   GIFtS: 55
GCID: GC22M042334

Centromere Protein M

(Previous name: chromosome 22 open reading frame 18)
(Previous symbol: C22orf18)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Centromere Protein M1 2     CENP-M2 3
C22orf181 2 3 5     Chromosome 22 Open Reading Frame 181
PANE12 3 5     bK250D10.22
Interphase Centromere Complex Protein 392 3     Proliferation Associated Nuclear Element 12
Proliferation-Associated Nuclear Element Protein 12 3     ICEN393

External Ids:    HGNC: 183521   Entrez Gene: 790192   Ensembl: ENSG000001001627   OMIM: 6101525   UniProtKB: Q9NSP43   

Export aliases for CENPM gene to outside databases

Previous GC identifers: GC22M040664 GC22M025300


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CENPM Gene:
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on
which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized
by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128).
CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 (PubMed 16622419)).(supplied
by OMIM, Mar 2008)

GeneCards Summary for CENPM Gene:
CENPM (centromere protein M) is a protein-coding gene.

UniProtKB/Swiss-Prot: CENPM_HUMAN, Q9NSP4
Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in
assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits
the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into
centromeres

Gene Wiki entry for CENPM Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000022.10  NT_011520.13  NC_018933.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CENPM gene promoter:
         AP-1   ATF-2   HSF1 (long)   HSF1short   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCENPM promoter sequence
   Search Chromatin IP Primers for CENPM

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CENPM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

CENPM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CENPM gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22M042334:  view genomic region     (about GC identifiers)

Start:
42,334,725 bp from pter      End:
42,343,168 bp from pter
Size:
8,444 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: CENPM_HUMAN, Q9NSP4 (See protein sequence)
Recommended Name: Centromere protein M  
Size: 180 amino acids; 19737 Da
Subunit: Component of the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH, CENPM, CENPN, CENPT and
CENPU. The CENPA-NAC complex interacts with the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP,
CENPQ, CENPR and CENPS
Secondary accessions: A7LM22 B1AHQ9 Q6I9W3
Alternative splicing: 4 isoforms:  Q9NSP4-1   Q9NSP4-2   Q9NSP4-3   Q9NSP4-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CENPM: NX_Q9NSP4

Explore proteomics data for CENPM at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CENPM Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001002876.1  NP_001103685.1  NP_076958.1  

    ENSEMBL proteins: 
     ENSP00000215980   ENSP00000430624   ENSP00000384814   ENSP00000384731   ENSP00000384743  
     ENSP00000384132  
    Reactome Protein details: Q9NSP4

    CENPM Human Recombinant Protein Products:

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    antibodies-online peptides for CENPM

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR020987 Centromere_Cenp-M

    Graphical View of Domain Structure for InterPro Entry Q9NSP4

    ProtoNet protein and cluster: Q9NSP4


    Find genes that share domains with CENPM           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CENPM_HUMAN, Q9NSP4
    Function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in
    assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits
    the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into
    centromeres

    Phenotypes:
         1 GenomeRNAi human phenotype for CENPM:

     Decreased circadian period len 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for CENPM

    miRNA
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    miRTarBase miRNAs that target CENPM:
    hsa-mir-106b-5p (MIRT044255)

    Block miRNA regulation of human, mouse, rat CENPM using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CENPM_HUMAN, Q9NSP4: Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Nuclear in non-confluent cells
    and cytoplasmic in confluent or dividing cells (By similarity). Localizes in the kinetochore domain of
    centromeres
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol4
    extracellular2
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000777condensed chromosome kinetochore IEA--
    GO:0005634nucleus IEA--
    GO:0005829cytosol TAS--

    Find genes that share ontologies with CENPM           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CENPM About    
    See pathways by source

    SuperPathContained pathways About
    1Mitotic Metaphase and Anaphase
    Mitotic Anaphase0.94
    Mitotic Metaphase and Anaphase0.93
    Separation of Sister Chromatids0.94
    2Cell Cycle, Mitotic
    Cell Cycle, Mitotic0.90
    M Phase0.62
    Cell Cycle0.90
    3Mitotic Prometaphase
    Mitotic Prometaphase0.92
    Resolution of Sister Chromatid Cohesion0.92


    Find genes that share SuperPaths with CENPM           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    3 Reactome Pathways for CENPM
        Resolution of Sister Chromatid Cohesion
    Mitotic Prometaphase
    Separation of Sister Chromatids


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CENPM
    Interactions:

        Search GeneGlobe Interaction Network for CENPM

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CENPM (Q9NSP43 ENSP000002159804) via UniProtKB, MINT, STRING, and/or I2D (see all 68)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CENPAP494503, ENSP000003368684I2D: score=1 STRING: ENSP00000336868
    AHCTF1ENSP000003757054STRING: ENSP00000375705
    AURKBENSP000003139504STRING: ENSP00000313950
    BIRC5ENSP000003016334STRING: ENSP00000301633
    BUB1ENSP000003025304STRING: ENSP00000302530
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--

    Find genes that share ontologies with CENPM           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CENPM



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CENPM gene (3 alternative transcripts): 
    NM_001002876.1  NM_001110215.1  NM_024053.3  

    Unigene Cluster for CENPM:

    Centromere protein M
    Hs.208912  [show with all ESTs]
    Unigene Representative Sequence: AK123479
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000215980(uc003bbn.3 uc003bbo.3) ENST00000472374(uc010gyq.3)
    ENST00000404067 ENST00000402338 ENST00000407253 ENST00000402420 ENST00000396437(uc003bbp.1)
    ENST00000460824
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat CENPM
      QuantiFast Probe-based Assays in human, mouse, rat CENPM

    Additional mRNA sequence: 

    AK123479.1 AL160131.1 BC000705.2 BC007495.2 CR456399.1 CR457392.1 EU035297.1 

    9 DOTS entries:

    DT.210590  DT.100782520  DT.100782522  DT.95290054  DT.100782524  DT.101979497  DT.100782526  DT.100782525 
    DT.100681270 

    Selected AceView cDNA sequences (see all 181):

    BE893317 BM550851 CR456399 CA414668 BC007495 BM468525 AA721489 BE793850 
    BM451099 BQ056829 BQ880613 CR620369 BM461714 NM_001002876 BC000705 BE797487 
    AI652656 AW328206 CR613838 BI861387 AL160131 BF000589 BI858246 AI609359 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CENPM (see all 7)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b · 7c
    SP1:              -     -                 -           -           -                     
    SP2:              -     -                 -           -     -     -                     
    SP3:                                      -           -           -                     
    SP4:              -     -                 -                                             
    SP5:                                                  -                                 


    ECgene alternative splicing isoforms for CENPM

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CENPM expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTTCGTGCT
    CENPM Expression
    About this image

    CENPM Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CENPM Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.208912

    UniProtKB/Swiss-Prot: CENPM_HUMAN, Q9NSP4
    Tissue specificity: Isoform 3 is highly expressed in spleen, and intermediately in heart, prostate and ovary.
    Isoform 3 is highly expressed in resting CD19 B-cells and B-lineage chronic lymphocytic leukemia (B-CLL) cells
    and weakly expressed in activated B-cells. Isoform 1 is selectively expressed in activated CD19 cells and weakly
    in resting CD19 B-cells

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CENPM gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cenpm1 , 5 centromere protein M1, 5 82.41(n)1
    79.44(a)1
      15 (38.56 cM)5
    665701  NM_025639.41  NP_079915.11 
     822337795 
    chicken
    (Gallus gallus)
    Aves CENPM1 centromere protein M 65.62(n)
    59.37(a)
      417982  NM_001044638.1  NP_001038103.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    53(a)
    53(a)
    many → 1
    many → 1
    5(26969088-26980107)
    GL343327.1(1140561-1140809)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cenpm1 centromere protein M 58.54(n)
    51.25(a)
      549929  NM_001017175.2  NP_001017175.1 
    zebrafish
    (Danio rerio)
    Actinopterygii pane11 proliferation associated nuclear element 53.8(n)
    43.67(a)
      402852  NM_205590.2  NP_991153.2 


    ENSEMBL Gene Tree for CENPM (if available)
    TreeFam Gene Tree for CENPM (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CENPM (see all 263)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs110900641,2
    A--42334392(+) tgaggG/Tggagt 3 -- ds5001 int10--------
    rs1825947991,2
    C--42334458(+) TCCGCA/CTCCCG 3 -- ds5001 int10--------
    rs1179625601,2
    C,F--42334588(+) GGTCTC/TGAATT 3 -- ds5001 int11Minor allele frequency- T:0.13NA 120
    rs1876439831,2
    --42334612(+) GATCCA/GCCCAC 3 -- ds5001 int10--------
    rs81358041,2
    C,F,H--42334660(+) ctctgC/Tacctg 3 -- ds5001 int115Minor allele frequency- T:0.15NS EA NA WA CSA 1978
    rs1469552541,2
    C--42334660(+) CTCTG-/CACCTG 3 -- ds5001 int10--------
    rs60025471,2
    C,F--42334748(+) ATTTTT/AAAACT 3 -- ut311Minor allele frequency- A:0.38WA 118
    rs10479971,2
    C,F,A--42334953(-) AGCCCG/CCCGTG 3 -- ut318Minor allele frequency- C:0.29MN NA WA CSA EA 551
    rs1380556021,2
    C,F--42335147(+) GCACAG/AATCTG 5 /I syn1 ut311Minor allele frequency- A:0.00NA 4386
    rs1842533201,2
    --42335201(+) TCCACC/TTGCGG 3 -- spa10--------

    HapMap Linkage Disequilibrium report for CENPM (42334725 - 42343168 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CENPM:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1711771CNV Insertion17803354
    esv2543828CNV Insertion19546169
    nsv508736CNV Insertion20534489
    dgv4979n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CENPM
    DNA2.0 Custom Variant and Variant Library Synthesis for CENPM

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610152    OMIM disorders: --


    Find genes that share disorders with CENPM           About GenesLikeMe

    Genetic Association Database (GAD): CENPM
    Human Genome Epidemiology (HuGE) Navigator: CENPM (1 document)

    Export disorders for CENPM gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CENPM gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with CENPM)
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    world of online information

    1. The human CENP-A centromeric nucleosome-associated complex. (PubMed id 16622419)1, 2, 3 Foltz D.R....Cleveland D.W. (Nat. Cell Biol. 2006)
    2. The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL. (PubMed id 16391015)1, 2, 9 Brickner A.G.... Warren E.H. (Blood 2006)
    3. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (Occup Environ Med 2009)
    4. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. (PubMed id 16622420)1, 3 Okada M.... Fukagawa T. (Nat. Cell Biol. 2006)
    5. Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. (PubMed id 16716197)1, 2 Izuta H.... Yoda K. (Genes Cells 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    9. The proliferation associated nuclear element (PANE1) is conserved between mammals and fish and preferentially expressed in activated lymphoid cells. (PubMed id 15183305)1, 2 Bierie B.... Hennighausen L. (Gene Expr. Patterns 2004)
    10. Reevaluating human gene annotation: a second-generation analysis of chromosome 22. (PubMed id 12529303)1, 2 Collins J.E.... Dunham I. (Genome Res. 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79019 HGNC: 18352 AceView: C22orf18 Ensembl:ENSG00000100162 euGenes: HUgn79019
    ECgene: CENPM H-InvDB: CENPM

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CENPM Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CENPM gene:
    Search GeneIP for patents involving CENPM

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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