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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CENPI Gene

protein-coding   GIFtS: 53
GCID: GC0XP100353

Centromere Protein I

(Previous names: FSH primary response (LRPR1, rat) homolog 1, FSH primary...)
(Previous symbol: FSHPRH1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Centromere Protein I1 2     FSH Primary Response Protein 12 3
FSHPRH11 2 3 5     FSH Primary Response (LRPR1 Homolog, Rat) 11
LRPR12 3 5     FSH Primary Response (LRPR1, Rat) Homolog 11
Follicle-Stimulating Hormone Primary Response Protein2 3     Mis62
Interphase Centromere Complex Protein 192 3     FSH Primary Response 12
Leucine-Rich Primary Response Protein 12 3     ICEN193
CENP-I2 3     

External Ids:    HGNC: 39681   Entrez Gene: 24912   Ensembl: ENSG000001023847   OMIM: 3000655   UniProtKB: Q926743   

Export aliases for CENPI gene to outside databases

Previous GC identifers: GC0XP100241 GC0XP090157


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CENPI Gene:
The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene
is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis. (provided by
RefSeq, Jul 2008)

GeneCards Summary for CENPI Gene: 
CENPI (centromere protein I) is a protein-coding gene. Diseases associated with CENPI include scleroderma, and liver disease, and among its related super-pathways are Mitotic Anaphase and Mitotic Prometaphase. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: CENPI_HUMAN, Q92674
Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is
involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in
incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the
response of gonadal tissues to follicle-stimulating hormone

Gene Wiki entry for CENPI Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NT_011651.17  NC_018934.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CENPI gene promoter:
         Max1   NF-1/L   NF-1   POU6F1 (c2)   NF-AT   NF-AT4   NF-AT2   NF-AT3   NF-AT1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCENPI promoter sequence
   Search SABiosciences Chromatin IP Primers for CENPI

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CENPI


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.1   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22.1

CENPI Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CENPI gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP100353:  view genomic region     (about GC identifiers)

Start:
100,353,178 bp from pter      End:
100,418,670 bp from pter
Size:
65,493 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CENPI_HUMAN, Q92674 (See protein sequence)
Recommended Name: Centromere protein I  
Size: 756 amino acids; 86720 Da
Subunit: Component of the CENPA-CAD complex, composed of CENPI, CENPK, CENPL, CENPO, CENPP, CENPQ, CENPR and
CENPS. The CENPA-CAD complex interacts with the CENPA-NAC complex, at least composed of CENPA, CENPC, CENPH,
CENPM, CENPN, CENPT and MLF1IP/CENPU. Interacts with SENP6
Subcellular location: Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The
CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex
Secondary accessions: Q5JWZ9 Q96ED0
Alternative splicing: 2 isoforms:  Q92674-1   Q92674-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CENPI: NX_Q92674

Explore proteomics data for CENPI at MOPED 

Post-translational modifications:

  • UniProtKB: Sumoylated. Sumoylated form can be polyubiquitinated by RNF4, leading to its degradation. Desumoylation by SENP6
    prevents its degradation
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q92674

  • CENPI Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CENPI Protein Expression
    REFSEQ proteins: NP_006724.2  
    ENSEMBL proteins: 
     ENSP00000384546   ENSP00000409173   ENSP00000362017   ENSP00000362018   ENSP00000399274  
     ENSP00000218507  
    Reactome Protein details: Q92674
    Human Recombinant Protein Products for CENPI: 
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    Novus Biologicals CENPI Lysate
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CENPI 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000776kinetochore IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005829cytosol TAS--

    CENPI for ontologies           About GeneDecksing



    CENPI Antibody Products: 
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    Cloud-Clone Corp. ELISAs for CENPI 
    Cloud-Clone Corp. CLIAs for CENPI


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR012485 Centromere_CenpI

    Graphical View of Domain Structure for InterPro Entry Q92674

    ProtoNet protein and cluster: Q92674

    1 Blocks protein domain: IPB012485 Mis6

    UniProtKB/Swiss-Prot: CENPI_HUMAN, Q92674
    Similarity: Belongs to the mis6 family


    CENPI for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CENPI_HUMAN, Q92674
    Function: Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is
    involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in
    incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
    Required for the localization of CENPF, MAD1L1 and MAD2 (MAD2L1 or MAD2L2) to kinetochores. Involved in the
    response of gonadal tissues to follicle-stimulating hormone
    Induction: By follicle-stimulating hormone (FSH)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    CENPI for ontologies           About GeneDecksing


    Phenotypes:
         5 GenomeRNAi human phenotypes for CENPI:
     Abundance of large cells with   Cell cycle / mitosis defect  Decreased cell number, increas  Increased gamma-H2AX phosphory 
     Increased number of mitotic ce 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CENPI 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CENPI 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CENPI 

    miRNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CENPI About                                                                                                See pathways by source

    SuperPathContained pathways About
    1M Phase
    Mitotic Anaphase0.94
    M Phase0.88
    Separation of Sister Chromatids0.94
    Mitotic M-M/G1 phases0.88
    Mitotic Metaphase and Anaphase0.94
    2Resolution of Sister Chromatid Cohesion
    Resolution of Sister Chromatid Cohesion0.93
    Mitotic Prometaphase0.93
    3Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    4Packaging Of Telomere Ends
    Nucleosome assembly0.46
    Deposition of New CENPA-containing Nucleosomes at the Centromere0.46
    5Meiotic Synapsis
    Chromosome Maintenance0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/12        Reactome Pathways for CENPI (see all 12)
        Mitotic Metaphase and Anaphase
    Mitotic Prometaphase
    Resolution of Sister Chromatid Cohesion
    Nucleosome assembly
    Mitotic Anaphase



    CENPI for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CENPI

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/81 Interacting proteins for CENPI (Q926743 ENSP000002185074) via UniProtKB, MINT, STRING, and/or I2D (see all 81)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CENPAP494503, ENSP000003368684I2D: score=1 STRING: ENSP00000336868
    AURKBENSP000003139504STRING: ENSP00000313950
    BIRC5ENSP000003016334STRING: ENSP00000301633
    BUB1ENSP000003025304STRING: ENSP00000302530
    BUB1BENSP000002875984STRING: ENSP00000287598
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000278mitotic cell cycle TAS--
    GO:0006334nucleosome assembly TAS--
    GO:0007548sex differentiation TAS8921378
    GO:0034080CENP-A containing nucleosome assembly at centromere TAS--
    GO:0034508centromere complex assembly ----

    CENPI for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CENPI

    Search CenterWatch for drugs/clinical trials and news about CENPI

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CENPI gene: 
    NM_006733.2  

    Unigene Clusters for CENPI:

    Centromere protein I
    Hs.348920  [show with all ESTs], Hs.737663
    Unigene Representative Sequences: AK302986, BC005967
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000403304 ENST00000435570 ENST00000372926(uc004egy.3) ENST00000372927
    ENST00000423383(uc004egx.3) ENST00000218507(uc011mrg.2)
    miRNA
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    Sirion Biotech Customized lentivirus for stable overexpression of CENPI 
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CENPI

    Additional mRNA sequence: BC005967.1 

    8 DOTS entries:

    DT.454076  DT.95117641  DT.91756782  DT.95240051  DT.91710750  DT.95240050  DT.121288043  DT.121288039 

    2 AceView cDNA sequences:

    BC005967 BF213649 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CENPI    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21
    SP1:                                                                                                                                                      
    SP2:                          -                                                                                                                           
    SP3:                          -                                                                                                                           
    SP4:                                                                                                                                                      
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for CENPI

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CENPI expression in normal human tissues (normalized intensities)      CENPI embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CENPI Expression
    About this image


    CENPI expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Lung (Respiratory System)
             Human Pulmonary Fibroblasts (HPF)   
     
     Blood (Hematopoietic System)
             Proerythroblasts Hematopoietic Bone Marrow
     
     Fibroblast (Respiratory System)
             Human Pulmonary Fibroblasts (HPF)   

    See CENPI Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CENPI

    SOURCE GeneReport for Unigene clusters: Hs.348920 Hs.737663
        SABiosciences Custom PCR Arrays for CENPI
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CENPI
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CENPI

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CENPI gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cenpi1 , 5 centromere protein I1, 5 80.91(n)1
    73.72(a)1
      X (56.08 cM)5
    1029201  NM_145924.21  NP_666036.11 
     1343080845 
    chicken
    (Gallus gallus)
    Aves CENPI1 centromere protein I 64.8(n)
    57.24(a)
      395207  NM_204532.1  NP_989863.1 
    lizard
    (Anolis carolinensis)
    Reptilia CENPI6
    centromere protein I
    52(a)
    1 ↔ 1
    GL343451.1(88113-105148)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.38592 Transcribed sequence with weak similarity to protein more 73.25(n)    142020952 
    zebrafish
    (Danio rerio)
    Actinopterygii cenpi1 centromere protein I 53.71(n)
    43.65(a)
      558570  XM_001920770.3  XP_001920805.1 


    ENSEMBL Gene Tree for CENPI (if available)
    TreeFam Gene Tree for CENPI (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CENPI gene

    CENPI for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for CENPI
    PGOHUM00000248507


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1158 SNPs in CENPI are shown (see all 1158)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1434716311,2
    --100319623(+) TCTGGG/TGTCAG 1 -- us2k10--------
    rs78869701,2
    C,F--100319684(+) ACACGA/TATTGT 1 -- us2k14Minor allele frequency- T:0.29NA WA 7
    rs1811964071,2
    --100319778(+) GCAACG/TGCCCA 1 -- us2k10--------
    rs1858943661,2
    --100319855(+) GCGTCG/TTCGCG 1 -- us2k10--------
    rs413002651,2
    C,F--100319924(+) GTGCGT/CTGCTC 1 -- us2k12Minor allele frequency- C:0.00NA 4
    rs1506615981,2
    --100320042(+) GGTAGA/GGTGTC 1 -- us2k10--------
    rs1409433031,2
    --100320356(+) CATTCC/TGACTA 1 -- us2k10--------
    rs1902680781,2
    --100320438(+) ATCCAA/GTTCTT 1 -- us2k10--------
    rs37614971,2
    C,F,H--100320531(-) TTGACC/TGTAGC 1 -- us2k120Minor allele frequency- N:0.00NA EA NS WA 2195
    rs566755161,2
    C,F--100320543(+) CCTCTC/TCTGGA 1 -- us2k11Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for CENPI (100353178 - 100418670 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CENPI: --

    Locus Specific Mutation Databases (LSDB): CENPI
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300065    OMIM disorders: --

    2 diseases for CENPI:    About MalaCards
    scleroderma    liver disease


    CENPI for disorders           About GeneDecksing

    Genetic Association Database (GAD): CENPI

    Export disorders for CENPI gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CENPI gene, integrated from 9 sources (see all 22):
    (articles sorted by number of sources associating them with CENPI)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The CENP-H-I complex is required for the efficient incorporation of newly synthesized CENP-A into centromeres. (PubMed id 16622420)1, 2, 3 Okada M....Fukagawa T. (2006)
    2. Sequence and chromosomal location of a human homologue of LRPR1, an FSH primary response gene. (PubMed id 8921378)1, 2, 9 Roberts R.G.... Bobrow M. (1996)
    3. The human CENP-A centromeric nucleosome-associated complex. (PubMed id 16622419)1, 2 Foltz D.R....Cleveland D.W. (2006)
    4. Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells. (PubMed id 16716197)1, 2 Izuta H.... Yoda K. (2006)
    5. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Human CENP-I specifies localization of CENP-F, MAD1 and MAD2 to kinetochores and is essential for mitosis. (PubMed id 12640463)1, 2 Liu S.-T....Yen T.J. (2003)
    8. Regulation of gene expression in Sertoli cells by follicle-stimulating hormone (FSH): cloning and characterization of LRPR1, a primary response gene encoding a leucine-rich protein. (PubMed id 7758824)1, 9 Slegtenhorst-Eegdeman K.E....Grootegoed J.A. (1995)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Anti-CENPI autoantibodies in scleroderma patients wit h features of autoimmune liver diseases. (PubMed id 21888900)1 Hamdouch K....Valdivia M.M. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2491 HGNC: 3968 AceView: FSHPRH1.1 Ensembl:ENSG00000102384 euGenes: HUgn2491
    ECgene: CENPI H-InvDB: CENPI

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CENPI Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CENPI gene:
    Search GeneIP for patents involving CENPI

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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