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Aliases for CENPBD1 Gene

Aliases for CENPBD1 Gene

  • CENPB DNA-Binding Domain Containing 1 2 3 5
  • CENPB DNA-Binding Domains Containing 1 2

External Ids for CENPBD1 Gene

Previous GeneCards Identifiers for CENPBD1 Gene

  • GC16M088567
  • GC16M090036
  • GC16M075729

Summaries for CENPBD1 Gene

GeneCards Summary for CENPBD1 Gene

CENPBD1 (CENPB DNA-Binding Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CENPBD1 Gene

Genomics for CENPBD1 Gene

Regulatory Elements for CENPBD1 Gene

Enhancers for CENPBD1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G089971 1.1 ENCODE 12.1 -0.6 -632 4.8 HDGF HNRNPUL1 PKNOX1 CREB3L1 AGO1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 DEF8 ENSG00000198211 TUBB3 CENPBD1 ENSG00000259877 URAHP ZNF778 MC1R CDK10 DBNDD1
GH16G089993 1.6 Ensembl ENCODE dbSUPER 5.2 -22.4 -22416 3.5 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ZFP64 ARID4B SIN3A ZNF2 ZBTB7B ENSG00000259877 AFG3L1P MC1R LINC00304 SPG7 DBNDD1 LOC101927863 GAS8 SNORD68 URAHP
GH16G089931 0.6 dbSUPER 13.3 +40.5 40498 1.5 BCOR ZNF263 ESRRA POLR2A ZMYM3 EBF1 DEF8 CENPBD1 AFG3L1P CDK10 MC1R ENSG00000259006 GC16P089938
GH16G089956 1.6 FANTOM5 Ensembl ENCODE 4.8 +15.1 15061 2.7 ATF1 PKNOX1 ARID4B SIN3A DMAP1 ZNF48 YY1 SLC30A9 GATA2 ELK1 DEF8 DBNDD1 CDK10 CENPBD1 GAS8-AS1 ENSG00000261317
GH16G089947 1 ENCODE 5 +24.0 24015 2.4 HDGF PKNOX1 FOXA2 MLX CREB3L1 ARID4B SIN3A ZNF2 ZBTB7B ZNF207 CDK10 DEF8 MC1R CENPBD1 FANCA ENSG00000261317
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CENPBD1 on UCSC Golden Path with GeneCards custom track

Promoters for CENPBD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000089801 -68 1401 HDGF HNRNPUL1 MLX CREB3L1 AGO1 ZFP64 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for CENPBD1 Gene

Chromosome:
16
Start:
89,969,775 bp from pter
End:
89,972,832 bp from pter
Size:
3,058 bases
Orientation:
Minus strand

Genomic View for CENPBD1 Gene

Genes around CENPBD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CENPBD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CENPBD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CENPBD1 Gene

Proteins for CENPBD1 Gene

  • Protein details for CENPBD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B2RD01-CENP1_HUMAN
    Recommended name:
    CENPB DNA-binding domain-containing protein 1
    Protein Accession:
    B2RD01

    Protein attributes for CENPBD1 Gene

    Size:
    187 amino acids
    Molecular mass:
    21052 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CENPBD1 Gene

Post-translational modifications for CENPBD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CENPBD1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CENPBD1 Gene

Domains & Families for CENPBD1 Gene

Gene Families for CENPBD1 Gene

Protein Domains for CENPBD1 Gene

Suggested Antigen Peptide Sequences for CENPBD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CENPBD1: view

No data available for UniProtKB/Swiss-Prot for CENPBD1 Gene

Function for CENPBD1 Gene

Gene Ontology (GO) - Molecular Function for CENPBD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with CENPBD1: view
genes like me logo Genes that share phenotypes with CENPBD1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CENPBD1 Gene

Localization for CENPBD1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CENPBD1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CENPBD1 gene
Compartment Confidence
nucleus 4
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for CENPBD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with CENPBD1: view

Pathways & Interactions for CENPBD1 Gene

SuperPathways for CENPBD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CENPBD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CENPBD1 Gene

Drugs & Compounds for CENPBD1 Gene

No Compound Related Data Available

Transcripts for CENPBD1 Gene

mRNA/cDNA for CENPBD1 Gene

Unigene Clusters for CENPBD1 Gene

CENPB DNA-binding domains containing 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CENPBD1 Gene

No ASD Table

Relevant External Links for CENPBD1 Gene

GeneLoc Exon Structure for
CENPBD1
ECgene alternative splicing isoforms for
CENPBD1

Expression for CENPBD1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CENPBD1 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CENPBD1 Gene



NURSA nuclear receptor signaling pathways regulating expression of CENPBD1 Gene:

CENPBD1

SOURCE GeneReport for Unigene cluster for CENPBD1 Gene:

Hs.513832
genes like me logo Genes that share expression patterns with CENPBD1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CENPBD1 Gene

Orthologs for CENPBD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CENPBD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CENPBD1 34
  • 63.53 (n)
cow
(Bos Taurus)
Mammalia CENPBD1 35
  • 53 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CENPBD1 35
  • 46 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CENPBD1 35
  • 8 (a)
OneToOne
Species where no ortholog for CENPBD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CENPBD1 Gene

ENSEMBL:
Gene Tree for CENPBD1 (if available)
TreeFam:
Gene Tree for CENPBD1 (if available)

Paralogs for CENPBD1 Gene

(1) SIMAP similar genes for CENPBD1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for CENPBD1 Gene

genes like me logo Genes that share paralogs with CENPBD1: view

No data available for Paralogs for CENPBD1 Gene

Variants for CENPBD1 Gene

Sequence variations from dbSNP and Humsavar for CENPBD1 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000069914 -- 89,969,866(+) GGTTT(C/G)CAGGG utr-variant-3-prime
rs1000464059 -- 89,972,592(+) TTGCG(C/T)ATGCG nc-transcript-variant, utr-variant-5-prime
rs1000744164 -- 89,973,444(+) CATGG(A/G)CACAA intron-variant, upstream-variant-2KB
rs1000794050 -- 89,972,738(+) ACCAG(C/T)GCGAG nc-transcript-variant, utr-variant-5-prime
rs1001177971 -- 89,973,271(+) ACTGT(A/C)GTTAA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CENPBD1 Gene

Variant ID Type Subtype PubMed ID
esv2762221 CNV gain+loss 21179565
esv3639603 CNV gain 21293372
esv3892941 CNV gain 25118596
nsv1066499 CNV loss 25217958
nsv428331 CNV gain+loss 18775914
nsv457626 CNV loss 19166990
nsv471119 CNV loss 18288195
nsv482951 CNV loss 15286789
nsv509640 CNV insertion 20534489
nsv573799 CNV gain 21841781
nsv573810 CNV loss 21841781
nsv573841 CNV loss 21841781
nsv573842 CNV loss 21841781

Variation tolerance for CENPBD1 Gene

Gene Damage Index Score: 3.90; 59.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CENPBD1 Gene

Human Gene Mutation Database (HGMD)
CENPBD1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CENPBD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CENPBD1 Gene

Disorders for CENPBD1 Gene

Relevant External Links for CENPBD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CENPBD1

No disorders were found for CENPBD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CENPBD1 Gene

Publications for CENPBD1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. (PMID: 14667819) Lehner B. … Sanderson C.M. (Genomics 2004) 3 64
  3. A protein interaction framework for human mRNA degradation. (PMID: 15231747) Lehner B. … Sanderson C.M. (Genome Res. 2004) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4 64

Products for CENPBD1 Gene

Sources for CENPBD1 Gene

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