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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CEND1 Gene

protein-coding   GIFtS: 47
GCID: GC11M000786

Cell Cycle Exit And Neuronal Differentiation 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cell Cycle Exit And Neuronal Differentiation 11 2
BM882 3 5
BM88 Antigen2 3
Cell Cycle Exit And Neuronal Differentiation Protein 12

External Ids:    HGNC: 241531   Entrez Gene: 512862   Ensembl: ENSG000001845247   OMIM: 6082135   UniProtKB: Q8N1113   

Export aliases for CEND1 gene to outside databases

Previous GC identifer: GC11M000603


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CEND1 Gene:
The protein encoded by this gene is a neuron-specific protein. The similar protein in pig enhances neuroblastoma
cell differentiation in vitro and may be involved in neuronal differentiation in vivo. Multiple pseudogenes have
been reported for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for CEND1 Gene: 
CEND1 (cell cycle exit and neuronal differentiation 1) is a protein-coding gene. Diseases associated with CEND1 include neuroblastoma, and beckwith-wiedemann syndrome, and among its related super-pathways are DNA Damage.

UniProtKB/Swiss-Prot: CEND_HUMAN, Q8N111
Function: Involved in neuroblastoma cell differentiation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.2  NT_009237.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CEND1 gene promoter:
         Oct-B1   oct-B2   oct-B3   Pax-5   p53   p300   YY1   POU2F1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCEND1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CEND1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEND1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.5   Ensembl cytogenetic band:  11p15.5   HGNC cytogenetic band: 11p15.5

CEND1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEND1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M000786:  view genomic region     (about GC identifiers)

Start:
787,104 bp from pter      End:
790,126 bp from pter
Size:
3,023 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CEND_HUMAN, Q8N111 (See protein sequence)
Recommended Name: Cell cycle exit and neuronal differentiation protein 1  
Size: 149 amino acids; 14954 Da
Subunit: Homodimer (By similarity)
Subcellular location: Membrane; Single-pass type IV membrane protein (Potential)
Secondary accessions: Q9NYM6

Explore the universe of human proteins at neXtProt for CEND1: NX_Q8N111

Explore proteomics data for CEND1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8N111

  • CEND1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CEND1 Protein Expression
    REFSEQ proteins: NP_057648.2  
    ENSEMBL proteins: 
     ENSP00000328336  

    Human Recombinant Protein Products for CEND1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CEND1
    OriGene Protein Over-expression Lysate for CEND1
    OriGene MassSpec for CEND1 
    OriGene Custom Protein Services for CEND1
    GenScript Custom Purified and Recombinant Proteins Services for CEND1
    Novus Biologicals CEND1 Protein
    Novus Biologicals CEND1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CEND1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    CEND1 for ontologies           About GeneDecksing



    CEND1 Antibody Products: 
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    Abcam antibodies for CEND1
    Cloud-Clone Corp. Antibodies for CEND1 
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    LSBio Antibodies in human, mouse, rat for CEND1 

    Assay Products for CEND1: 
    Browse Kits and Assays available from EMD Millipore
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    GenScript Custom Assay Services for CEND1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CEND1 
    Cloud-Clone Corp. CLIAs for CEND1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR020162 Cend1

    Graphical View of Domain Structure for InterPro Entry Q8N111

    ProtoNet protein and cluster: Q8N111

    UniProtKB/Swiss-Prot: CEND_HUMAN, Q8N111
    Similarity: Belongs to the CEND1 family


    CEND1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CEND_HUMAN, Q8N111
    Function: Involved in neuroblastoma cell differentiation (By similarity)

    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cend1):

     behavior/neurological  cellular  nervous system 

    CEND1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CEND1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CEND1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CEND1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CEND1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CEND1
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate CEND1 (see all 15):
    hsa-miR-137 hsa-miR-92a hsa-miR-25 hsa-miR-367 hsa-let-7a-2* hsa-miR-32 hsa-miR-33a hsa-let-7e*
    SwitchGear 3'UTR luciferase reporter plasmidCEND1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CEND1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEND1

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of CEND1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CEND1 (see all 6)
    OriGene ORF clones in mouse, rat for CEND1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CEND1 (NM_016564)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEND1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEND1
    Sirion Biotech Customized lentivirus for stable overexpression of CEND1 
                         Customized lentivirus expression plasmids for stable overexpression of CEND1 

    Cell Line
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    Search LifeMap BioReagents cell lines for CEND1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEND1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CEND1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1DNA Damage
    Cell Cycle / Checkpoint Control0.32
    2Neuroscience
    Neuroscience

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Cell Signaling Technology (CST) Pathways for CEND1
        Cell Cycle / Checkpoint Control
    Neuroscience



    CEND1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CEND1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CEND1 (Q8N1112, 3 ENSP000003283364) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBQLN4Q9NRR52, 3, ENSP000003572924MINT-2873110 I2D: score=3 STRING: ENSP00000357292
    EGFRP005333, ENSP000002754934I2D: score=2 STRING: ENSP00000275493
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007628adult walking behavior IEA--
    GO:0021686cerebellar granular layer maturation IEA--
    GO:0021702cerebellar Purkinje cell differentiation IEA--
    GO:0021933radial glia guided migration of cerebellar granule cell IEA--
    GO:0021941negative regulation of cerebellar granule cell precursor proliferation IEA--

    CEND1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CEND1 (CEND)

    Search CenterWatch for drugs/clinical trials and news about CEND1 / CEND

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CEND1 gene: 
    NM_016564.3  

    Unigene Cluster for CEND1:

    Cell cycle exit and neuronal differentiation 1
    Hs.22140  [show with all ESTs]
    Unigene Representative Sequence: BC034732
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000330106(uc001lrh.1) ENST00000524587
    miRNA
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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate CEND1 (see all 15):
    hsa-miR-137 hsa-miR-92a hsa-miR-25 hsa-miR-367 hsa-let-7a-2* hsa-miR-32 hsa-miR-33a hsa-let-7e*
    SwitchGear 3'UTR luciferase reporter plasmidCEND1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CEND1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEND1
    Clone
    Products:
         
    OriGene clones in human, mouse for CEND1 (see all 6)
    OriGene ORF clones in mouse, rat for CEND1
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    GenScript: all cDNA clones in your preferred vector: CEND1 (NM_016564)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEND1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEND1
    Sirion Biotech Customized lentivirus for stable overexpression of CEND1 
                         Customized lentivirus expression plasmids for stable overexpression of CEND1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CEND1
    OriGene qSTAR qPCR primer pairs in human, mouse for CEND1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CEND1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEND1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEND1

    Additional mRNA sequence: 

    AF235030.1 AK074547.1 AK312993.1 BC034732.1 

    5 DOTS entries:

    DT.310371  DT.120720817  DT.120720857  DT.120720819  DT.40109665 

    24/101 AceView cDNA sequences (see all 101):

    BQ070321 BM932330 BM920640 CB156402 AI278196 AW452289 BM661609 BQ067047 
    BQ897822 BQ717439 BM662871 BM700533 BQ722366 AL525429 BI917194 CD628015 
    BM920641 BX460412 AI568561 BQ882441 BM686147 BI752376 BQ068994 CD628027 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CEND1 expression in normal human tissues (normalized intensities)      CEND1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAGTTCAC
    CEND1 Expression
    About this image


    CEND1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Adult Dopaminergic Neurons Substantia Nigra pars Compacta
             ganglion/cranial/facial VII   
     
     Heart (Cardiovascular System)
             Outflow Tract
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Lower Urinary Tract (Urinary System)
             visceral organ/urethra of male   

    See CEND1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CEND1

    SOURCE GeneReport for Unigene cluster: Hs.22140

    UniProtKB/Swiss-Prot: CEND_HUMAN, Q8N111
    Tissue specificity: Neuron specific

        SABiosciences Custom PCR Arrays for CEND1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEND1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CEND1 gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cend11 , 5 cell cycle exit and neuronal differentiation 11, 5 81.96(n)1
    82.19(a)1
      7 (86.77 cM)5
    577541  NM_021316.41  NP_067291.11 
     1414264465 
    chicken
    (Gallus gallus)
    Aves CEND11 cell cycle exit and neuronal differentiation 1 58.53(n)
    50.39(a)
      770044  NM_001193263.1  NP_001180192.1 
    lizard
    (Anolis carolinensis)
    Reptilia CEND16
    Uncharacterized protein
    38(a)
    1 ↔ 1
    1(73931126-73931545)


    ENSEMBL Gene Tree for CEND1 (if available)
    TreeFam Gene Tree for CEND1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CEND1 gene

    CEND1 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for CEND1
    PGOHUM00000248532 PGOHUM00000248280


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/92 SNPs in CEND1 are shown (see all 92)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1160277261,2
    C,F--786617(+) GGCACC/TGCAGG 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1838631721,2
    --786641(+) TGGCCC/TGCATG 1 -- ds50010--------
    rs1494866891,2
    --786660(+) CCACCC/TGTGGC 1 -- ds50010--------
    rs71113061,2
    C,F--786684(-) CCGGCG/CGGCCT 1 -- ds50012Minor allele frequency- C:0.08NA 122
    rs1886399401,2
    --786789(+) GGCTGC/TGGAAG 1 -- ds50010--------
    rs99436781,2
    C--786953(+) GGTGGG/CGATCC 1 -- ds500114Minor allele frequency- C:0.28NA WA CSA EA 379
    rs1157243171,2
    F--786958(+) CGATCC/TGGGCC 1 -- ds50011Minor allele frequency- T:0.01WA 118
    rs118223611,2
    C,F,A,H--786975(+) CCTGGA/GATAAG 1 -- ds50012Minor allele frequency- G:0.05NA WA 120
    rs1928158471,2
    --787004(+) GGTCCC/TGTCAG 1 -- ds50010--------
    rs118223651,2
    C,F,H--787041(+) TGGAAA/GGCCTG 1 -- ds50013Minor allele frequency- G:0.03NA WA 210

    HapMap Linkage Disequilibrium report for CEND1 (787104 - 790126 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/15 variations for CEND1 (see all 15):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv182e199CNV Deletion23128226
    dgv946n71CNV Loss21882294
    dgv944n71CNV Loss21882294
    nsv469923CNV Loss18288195
    dgv921n71CNV Loss21882294
    dgv936n71CNV Loss21882294
    dgv945n71CNV Loss21882294
    dgv948n71CNV Loss21882294
    nsv896587CNV Loss21882294
    nsv896599CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CEND1
    DNA2.0 Custom Variant and Variant Library Synthesis for CEND1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 608213    OMIM disorders: --

    3 diseases for CEND1:    About MalaCards
    neuroblastoma    beckwith-wiedemann syndrome    neuronitis


    CEND1 for disorders           About GeneDecksing


    Export disorders for CEND1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CEND1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with CEND1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, expression and localization of human BM88 shows that it maps to chromosome 11p15.5, a region implicated in Beckwith-Wiedemann syndrome and tumorigenesis. (PubMed id 11311134)1, 2, 3 Gaitanou M.... Matsas R. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The Identification of Novel Proteins That Interact Wit h the GLP-1 Receptor and Restrain its Activity. (PubMed id 23864651)1 Huang X....Wheeler M.B. (2013)
    5. Regulation of epidermal growth factor receptor traffi cking by lysine deacetylase HDAC6. (PubMed id 20029029)1 Deribe Y.L....Dikic I. (2009)
    6. BM88/Cend1 expression levels are critical for proliferation and differentiation of subventricular zone-derived neural precursor cells. (PubMed id 18499894)1 Katsimpardi L....Thomaidou D. (2008)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
    9. Characterization of the BM88 promoter and identification of an 88 bp fragment sufficient to drive neurone-specific expression. (PubMed id 16181419)1 Papadodima O....Matsas R. (2005)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51286 HGNC: 24153 AceView: BM88 Ensembl:ENSG00000184524 euGenes: HUgn51286
    ECgene: CEND1 H-InvDB: CEND1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CEND1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CEND1 gene:
    Search GeneIP for patents involving CEND1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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