CELSR2 Gene
protein-coding GIFtS: 59
GCID: GC01P109792
|
|
cadherin, EGF LAG seven-pass G-type receptor 2(Previous names: cadherin, EGF LAG seven-pass G-type receptor 2, flamingo...)
(Previous symbol: EGFL2)
| |
Aliases
for CELSR2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cadherin, EGF LAG Seven-Pass G-Type Receptor 21 2 | | Multiple EGF-Like Domains Protein 32 3 | | EGFL21 2 3 5 | | Multiple Epidermal Growth Factor-Like Domains Protein 32 3 | | MEGF31 2 3 5 | | EGF-Like Protein 22 3 | | CDHF101 2 3 | | Cadherin, EGF LAG Seven-Pass G-Type Receptor 2, Flamingo (Drosophila) Homolog1 | | Flamingo11 2 | | Cadherin EGF LAG Seven-Pass G-Type Receptor 22 | | KIAA02791 3 | | Cadherin, EGF LAG Seven-Pass G-Type Receptor 2 (Flamingo Homolog, Drosophila)2 | | Cadherin Family Member 102 3 | | EGF-Like-Domain, Multiple 22 | | Epidermal Growth Factor-Like Protein 22 3 | | Epidermal Growth Factor-Like 22 | | Flamingo Homolog 32 3 | | Multiple Epidermal Growth Factor-Like Domains 32 |
Export aliases for CELSR2 gene to outside databasesPrevious GC identifers: GC01P110271 GC01P108722 GC01P108894 GC01P109092 GC01P109093 GC01P109504 GC01P109594 GC01P107685 |
Summaries
for CELSR2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CELSR2:
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingosubfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingocadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-likerepeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, acharacteristic unique to this subfamily. It is postulated that these proteins are receptors involved incontact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domainsinvolved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has notbeen determined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CELR2_HUMAN, Q9HCU4Function: Receptor that may have an important role in cell/cell signaling during nervous system formation
Gene Wiki entry for CELSR2
|
Genomic Views
for CELSR2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CELSR2 gene promoter:
C/EBPbeta Pax-2 Olf-1 Pax-2a YY1 Roaz CREB HEN1 USF-1 SEF-1 (1)
Other transcription factors
Search SABiosciences Chromatin IP Primers for CELSR2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CELSR2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p21 Ensembl cytogenetic band: 1p13.3 HGNC cytogenetic band: 1p13.3CELSR2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P109792: view genomic region
(about GC identifiers)
Start:
|
109,792,641 bp from pter |
End:
|
109,818,378 bp from pter |
Size:
|
25,738 bases |
Orientation:
|
plus strand |
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Proteins
for CELSR2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CELR2_HUMAN, Q9HCU4 (See
protein sequence)Recommended Name: Cadherin EGF LAG seven-pass G-type receptor 2 precursor Size: 2923 amino acids; 317453 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Secondary accessions: Q5T2Y7 Q92566Explore the universe of human proteins at neXtProt for CELSR2: NX_Q9HCU4
Post-translational modifications:
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGFdomains (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9HCU4
CELSR2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001399.1
ENSEMBL proteins: ENSP00000271332
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CELSR2 for ontologies About GeneDecksing
CELSR2 Antibody Products:
Assay Products for CELSR2: |
Protein
Domains /
Families
for CELSR2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CELSR2 for domains About GeneDecksing
5/17 InterPro domains/families (see all 17):Graphical View of Domain Structure for InterPro Entry Q9HCU4ProtoNet protein and cluster: Q9HCU4 5/7 Blocks protein families (see all 7): IPB000152 Aspartic acid and asparagine hydroxylation site IPB000203 GPS domain IPB000832 G-protein coupled receptors family 2 (secretin-like) IPB001791 Laminin G IPB001881 EGF-like calcium-binding
UniProtKB/Swiss-Prot: CELR2_HUMAN, Q9HCU4Similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamilySimilarity: Contains 9 cadherin domainsSimilarity: Contains 7 EGF-like domainsSimilarity: Contains 1 GPS domainSimilarity: Contains 1 laminin EGF-like domainSimilarity: Contains 2 laminin G-like domains |
Function
for CELSR2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CELR2_HUMAN, Q9HCU4Function: Receptor that may have an important role in cell/cell signaling during nervous system formation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CELSR2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CELSR2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CELSR2 (NM_001408) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CELSR2 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CELSR2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELSR2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CELSR2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CELSR2:
Animal Models:
Mouse knock-out Celsr2tm1Lex for CELSR2
4 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Celsr2):
CELSR2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CELSR2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | GPCRs, Other | | | 2 | Selected targets of ESR1 | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 EMD Millipore Pathway for CELSR2
1  BioSystems Pathway for CELSR2
CELSR2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CELSR2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/11 Interacting proteins for CELSR2 (Q9HCU42, 3 ENSP000002713324) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table
CELSR2 for ontologies About GeneDecksing
|
Drugs & Compounds
for CELSR2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CELSR2
Search CenterWatch for drugs/clinical trials and news about CELSR2 / CELR2
|
Transcripts
for CELSR2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CELSR2 gene: NM_001408.2 Unigene Cluster for CELSR2: Cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) Hs.57652 [show with all ESTs]Unigene Representative Sequence: NM_0014085 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000271332(uc001dxa.4) ENST00000491918 ENST00000459940 ENST00000489018
ENST00000498157
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CELSR2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CELSR2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CELSR2 (NM_001408) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CELSR2 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CELSR2 |
Additional cDNA sequence: AF234887.1 AK124727.1 AK309093.1 D87469.2 11 DOTS entries: DT.113261 DT.99953237 DT.100024122 DT.40113927 DT.121402526 DT.91744340 DT.101971422 DT.40131212 DT.100754730 DT.75102404 DT.86854745 24/165 AceView cDNA sequences (see all 165): BX409742 BM718885 AA349458 AL120631 BU173510 AL704729 CB122348 BU857213 BI488557 AU116945 BU849091 BM695426 AL135351 AF234887 BP352704 BQ679970 BX460356 BQ676596 BM690359 BM480097 BM930834 BI914159 CD611589 AK127086
GeneLoc Exon Structure
5/23 Alternative Splicing Database (ASD) splice patterns (SP) for CELSR2 (see all 23) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12a | · | 12b | · | 12c | ^ | 13 | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | |
| ExUns: | 18 | ^ | 19a | · | 19b | ^ | 20a | · | 20b | ^ | 21a | · | 21b | ^ | 22a | · | 22b | ^ | 23a | · | 23b | ^ | 24 | ^ | 25a | · | 25b | ^ | 26 | ^ | 27a | · | 27b | ^ | 28 | ^ | 29a | · | 29b | · | 29c | ^ | 30a | · | 30b | ^ | 31a | · | 31b | ^ | 32a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | |
| ExUns: | 32b | · | 32c | ^ | 33a | · | 33b | ^ | 34 | ^ | 35a | · | 35b | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41a | · | 41b | · | 41c |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CELSR2
|
Expression
for CELSR2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CELSR2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCCATACTA
About this image
See CELSR2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CELSR2
SOURCE GeneReport for Unigene cluster: Hs.57652
UniProtKB/Swiss-Prot: CELR2_HUMAN, Q9HCU4Tissue specificity: Highest expression in brain and testis
SABiosciences Expression via Pathway-Focused PCR Array including CELSR2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CELSR2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CELSR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CELSR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CELSR2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELSR2 |
Orthologs
for CELSR2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CELSR2 gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
CELSR26 |
-- |
76(a) |
1 ↔ 1 |
4(124951903-125077089) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.139982 |
Xenopus laevis transcribed sequence with weak similarity more |
72.68(n) |
|
BU912872.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
celsr21 |
cadherin, EGF LAG seven-pass G-type receptor 2 |
66.56(n)
67.23(a) |
|
560426 NM_001080577.1 NP_001074046.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
stan3 |
dendrite morphogenesis transmembrane
receptor |
40(a)
(best of 4) |
|
-- |
worm
(Caenorhabditis elegans) |
Secernentea |
fmi-16 |
CaDHerin family member (cdh-6) |
10(a) |
1 → many |
V(13019053-13033384) |
ENSEMBL Gene Tree for CELSR2 (if available)
TreeFam Gene Tree for CELSR2 (if available) |
Paralogs
for CELSR2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CELSR2 gene
- CDH232 DCHS12 CDHR22 DCHS22 CELSR32 FAT22 CELSR12 CDHR12
- PCDH152 FAT42 FAT32 FAT12
4 SIMAP similar genes for CELSR2 using alignment to 1 protein entry: CELR2_HUMAN:CELSR1 CELSR3 RESDA1 CDH23
CELSR2 for paralogs About GeneDecksing
|
Genomic Variants
for CELSR2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CELSR2 (109792641 - 109818378 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CELSR2
2 CNVs: 48081 48080 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CELSR2 |
|
Disorders
/ Diseases
for CELSR2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CELSR2 for disorders About GeneDecksing
OMIM gene information: 604265
OMIM disorders: --
9  diseases for CELSR2: About MalaCardsdeep vein thrombosis pulmonary embolism coronary heart disease strabismus
myocardial infarction thrombosis protein s deficiency dementia
cholesterol
Human Genome Epidemiology (HuGE) Navigator: CELSR2 (24 documents)
Export disorders for CELSR2 gene to outside databases
|
Publications
for CELSR2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CELSR2 gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with CELSR2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human homologue of flamingo, EGFL2, encodes a brain-expressed large cadherin-like protein with epidermal growth factor-like domains, and maps to chromosome 1p13.3-p21.1. (PubMed id 10907856)1, 2, 3 Vincent J.B.... Scherer S.W. (2000)
- Identification of high-molecular-weight proteins with multiple EGF- like motifs by motif-trap screening. (PubMed id 9693030)1, 3 Nakayama M.... Ohara O. (1998)
- Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PubMed id 9039502)1, 2 Nagase T....Nomura N. (1996)
- Eight genetic loci associated with variation in lipopr otein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studi es. (PubMed id 22003152)1 Grallert H....Ballantyne C.M. (2012)
- Large-scale genome-wide association studies in East As ians identify new genetic loci influencing metabolic traits. (PubMed id 21909109)1 Kim Y.J....Cho Y.S. (2011)
- Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C 4 genes are associated with multiple cardiovascular-related traits. (PubMed id 21943158)1 Middelberg R.P....Whitfield J.B. (2011)
- A genome-wide association study in Europeans and Sout h Asians identifies five new loci for coronary artery disease. (PubMed id 21378988)1 (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Genome-wide association study of coronary heart disea se and its risk factors in 8,090 African Americans: the NHLBI CARe Project. (PubMed id 21347282)1 Lettre G....Boerwinkle E. (2011)
- Mindbomb 1, an E3 ubiquitin ligase, forms a complex w ith RYK to activate Wnt/I^-catenin signaling. (PubMed id 21875946)1 Berndt J.D....Moon R.T. (2011)
|
External Searches for CELSR2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CELSR2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing CELSR2 gene
(According to HUGE)
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Specialized Databases showing CELSR2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for CELSR2 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for CELSR2 gene:
Search GeneIP for patents involving CELSR2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CELSR2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CELSR2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CELSR2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CELSR2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CELSR2 | | OriGene 3'-UTR Clone for CELSR2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CELSR2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CELSR2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CELSR2 | | OriGene Custom Protein Services for CELSR2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CELSR2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CELSR2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CELSR2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CELSR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CELSR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CELSR2 |
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| | | | Search Tocris compounds for CELSR2 |
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 | | | CELSR2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELSR2 |
|  |  |  | | | | ThermoFisher Antibodies for CELSR2 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CELSR2 |
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