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carboxyl ester lipase pseudogene(Previous name: carboxyl ester lipase-like (bile salt-stimulated lipase-like)...)
(Previous symbol: CELL)
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Aliases
for CELP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Carboxyl Ester Lipase Pseudogene1 2 | | Cell21 | | CELL1 2 4 | | Cell31 | | Carboxyl Ester Lipase-Like (Bile Salt-Stimulated Lipase-Like)1 | | CEL4 | | Cell11 | | Carboxyl Ester Lipase-Like Protein4 |
| External Ids: | HGNC: 18491 | Entrez Gene: 10572 | Ensembl: ENSG000001708277 | UniProtKB: Q140184 | | ORGUL members: | |
|---|
| NONCODE:n405255 | |
Export aliases for CELP gene to outside databasesPrevious GC identifers: GC09P127514 GC09P129311 GC09P131233 GC09P132987 GC09P134947 GC09P105451
|---|
Summaries
for CELP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CELP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_035014.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CELP gene promoter:
AP-2alpha isoform 3 AP-1 AP-2alpha isoform 4 AP-2alpha isoform 2 AP-2alpha AP-2alphaA ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for CELP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CELP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q34.3 Ensembl cytogenetic band: 9q34.2 HGNC cytogenetic band: 9q34.3CELP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09P135958: view genomic region
(about GC identifiers)
Start:
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135,957,926 bp from pter |
End:
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135,962,742 bp from pter |
Size:
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4,817 bases |
Orientation:
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plus strand |
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Proteins
for CELP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/TrEMBL: Q14018 (See
protein sequence)Recommended Name: Carboxyl ester lipase (Bile salt-stimulated lipase), isoform CRA_a Size: 59 amino acids; 6208 Da |
Protein
Domains /
Families
for CELP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q14018 |
Function
for CELP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELP |
|
Pathways & Interactions
for CELP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CELP
|
Drugs & Compounds
for CELP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Compounds for CELP available from Tocris Bioscience About this table
| Compound | Action |
CAS
# |
|---|
| Orlistat | Pancreatic, gastric and carboxylester lipase inhibitor; antiobesity and antihypercholesterolemic activity | [96829-58-2] |
Search CenterWatch for drugs/clinical trials and news about CELP 
|
Transcripts
for CELP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for CELP: Carboxyl ester lipase pseudogene Hs.654361 [show with all ESTs]Unigene Representative Sequence: L148132 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000421286 ENST00000411440(uc011mcu.1)
Additional cDNA sequence: L14813.1 NR_001275.2 5 DOTS entries: DT.40119873 DT.75163462 DT.86840803 DT.121143229 DT.121143238 24/32 AceView cDNA sequences (see all 32): AK098728 BM055183 CD612866 CD612864 AF081673 CD612868 CD612870 L14813 CK904837 AW371544 CD612859 BM352607 BC042510 S70516 M85201 CD612861 BF883469 NM_001807 S79774 X54457 NR_001275 CD612857 S70517 C75365
GeneLoc Exon Structure
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Expression
for CELP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CELP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCCTCCACAG
About this image
Genevestigator expression for CELP
SOURCE GeneReport for Unigene cluster: Hs.654361
SABiosciences Custom PCR Arrays for CELP
Primer
Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CELP
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CELP | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CELP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CELP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELP |
Orthologs
for CELP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
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ENSEMBL Gene Tree for CELP (if available)
TreeFam Gene Tree for CELP (if available) |
Paralogs
for CELP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CELP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CELP (135957926 - 135962742 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CELP
3 CNVs: 36925 83208 96330 | SABiosciences Cancer Mutation PCR Assays |
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Disorders
/ Diseases
for CELP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CELP for disorders About GeneDecksing
2  diseases for CELP: About MalaCardscholesterol pancreatitis
Export disorders for CELP gene to outside databases
|
Publications
for CELP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CELP gene integrated from 9 sources:
(articles sorted by number of sources associating them with CELP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Genomic organization, sequence analysis, and chromosomal localization of the human carboxyl ester lipase (CEL) gene and a CEL-like (CELL) gene. (PubMed id 1639390)1, 3, 9 Lidberg U.... Bjursell G. (1992)
- The human carboxyl ester lipase-like (CELL) gene is ubiquitously expressed and contains a hypervariable region. (PubMed id 7691717)1, 9 Nilsson J.... Bjursell G. (1993)
- Structure of the human pancreatic cholesterol esterase gene. (PubMed id 1627550)1 Kumar B.V.... Lange L.G. (1992)
- Processed pseudogenes: characteristics and evolution. (PubMed id 3909943)1 Vanin E.F. (1985)
- Characterization of the gorilla carboxyl ester lipase locus, and the appearance of the carboxyl ester lipase pseudogene during primate evolution. (PubMed id 10548728)9 Madeyski K....Nilsson J. (1999)
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External Searches for CELP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CELP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CELP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CELP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CELP gene:
Search GeneIP for patents involving CELP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CELP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | | | |
 |
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CELP | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CELP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CELP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CELP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CELP | | | Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CELP |
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 |  |  |  | |
| | | | Tocris compounds for CELP |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELP |
|  |  |  | | | | Search ThermoFisher Antibodies for CELP |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CELP |
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Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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