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CELF6 Gene

protein-coding   GIFtS: 49
GCID: GC15M072577

CUGBP, Elav-Like Family Member 6

(Previous names: Bruno (Drosophila) -like 6, RNA binding protein, bruno-like...)
(Previous symbol: BRUNOL6)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CUGBP, Elav-Like Family Member 61 2     Bruno (Drosophila) -Like 6, RNA Binding Protein1
BRUNOL61 2 3 5     Bruno-Like 6, RNA Binding Protein (Drosophila)1
Bruno-Like Protein 62 3     Bruno -Like 6, RNA Binding Protein2
CELF-62 3     Bruno-Like 6, RNA Binding Protein2
CUG-BP- And ETR-3-Like Factor 62 3     CUG-BP And ETR-3 Like Factor 62
RNA-Binding Protein BRUNOL-62 3     CUGBP Elav-Like Family Member 62

External Ids:    HGNC: 140591   Entrez Gene: 606772   Ensembl: ENSG000001404887   OMIM: 6126815   UniProtKB: Q96J873   

Export aliases for CELF6 gene to outside databases

Previous GC identifer: GC15M049407


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CELF6 Gene:
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one
C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of
this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and
translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified
in this gene. (provided by RefSeq, Feb 2010)

GeneCards Summary for CELF6 Gene:
CELF6 (CUGBP, Elav-like family member 6) is a protein-coding gene. Diseases associated with CELF6 include bovine spongiform encephalopathy, and choroiditis. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is CELF1.

UniProtKB/Swiss-Prot: CELF6_HUMAN, Q96J87
Function: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon
inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated
alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer
(MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000015.10  NC_018926.2  NT_010194.18  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CELF6
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCELF6 promoter sequence
   Search Chromatin IP Primers for CELF6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CELF6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q24   Ensembl cytogenetic band:  15q23   HGNC cytogenetic band: 15q24

CELF6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CELF6 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M072577:  view genomic region     (about GC identifiers)

Start:
72,577,068 bp from pter      End:
72,612,525 bp from pter
Size:
35,458 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CELF6_HUMAN, Q96J87 (See protein sequence)
Recommended Name: CUGBP Elav-like family member 6  
Size: 481 amino acids; 50477 Da
Sequence caution: Sequence=BAC85148.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for CELF6:
2DGQ (3D)    
Secondary accessions: B4DG28 B4DJB6 Q6PII4 Q6ZNJ7 Q8N607
Alternative splicing: 4 isoforms:  Q96J87-1   Q96J87-2   Q96J87-3   Q96J87-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CELF6: NX_Q96J87

Explore proteomics data for CELF6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CELF6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001166155.1  NP_001166156.1  NP_443072.3  

    ENSEMBL proteins: 
     ENSP00000287202   ENSP00000400439   ENSP00000439956   ENSP00000457863   ENSP00000378677  
     ENSP00000443162  

    CELF6 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q96J87

    ProtoNet protein and cluster: Q96J87

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: CELF6_HUMAN, Q96J87
    Similarity: Belongs to the CELF/BRUNOL family
    Similarity: Contains 3 RRM (RNA recognition motif) domains


    CELF6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CELF6_HUMAN, Q96J87
    Function: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon
    inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated
    alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer
    (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding NAS14761971
         
    CELF6 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Celf6):
     behavior/neurological  growth/size/body  homeostasis/metabolism  nervous system 

    CELF6 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Celf6tm1.2Jdd for CELF6

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CELF6
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CELF6

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CELF6 (see all 54):
    hsa-miR-3194-5p hsa-miR-29a hsa-miR-200a hsa-miR-488 hsa-miR-342-3p hsa-miR-449a hsa-miR-218 hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidCELF6 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CELF6

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 3): CELF6 (NM_052840)
    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELF6


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CELF6_HUMAN, Q96J87: Nucleus (By similarity). Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    mitochondrion2
    endoplasmic reticulum1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus NAS14761971
    GO:0005737cytoplasm NAS14761971

    CELF6 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CELF6
    Interactions:

        Search GeneGlobe Interaction Network for CELF6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CELF6 (ENSP000002872024) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BECN1ENSP000003552314STRING: ENSP00000355231
    RAD54L2ENSP000003865204STRING: ENSP00000386520
    USO1ENSP000004116984STRING: ENSP00000411698
    RBFOX2ENSP000004130354STRING: ENSP00000413035
    RBPMS2ENSP000003000694STRING: ENSP00000300069
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000381regulation of alternative mRNA splicing, via spliceosome IDA14761971
    GO:0006397mRNA processing IEA--

    CELF6 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CELF6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CELF6 gene (3 alternative transcripts): 
    NM_001172684.1  NM_001172685.1  NM_052840.4  

    Unigene Cluster for CELF6:

    CUGBP, Elav-like family member 6
    Hs.348342  [show with all ESTs]
    Unigene Representative Sequence: NM_052840
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000287202(uc010ukl.1) ENST00000437872 ENST00000543764 ENST00000567083
    ENST00000569311 ENST00000395258(uc010biw.2) ENST00000539635
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CELF6 (see all 54):
    hsa-miR-3194-5p hsa-miR-29a hsa-miR-200a hsa-miR-488 hsa-miR-342-3p hsa-miR-449a hsa-miR-218 hsa-miR-141
    SwitchGear 3'UTR luciferase reporter plasmidCELF6 3' UTR sequence
    Inhib. RNA
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CELF6
    Primer
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    OriGene qPCR primer pairs and template standards for CELF6
    OriGene qSTAR qPCR primer pairs in human, mouse for CELF6
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CELF6
      QuantiTect SYBR Green Assays in human, mouse, rat CELF6
      QuantiFast Probe-based Assays in human, mouse, rat CELF6

    Additional mRNA sequence: 

    AF401233.1 AF425606.1 AK294382.1 AK296004.1 BC030835.1 

    5 DOTS entries:

    DT.121081454  DT.121081411  DT.447310  DT.97807621  DT.100743084 

    Selected AceView cDNA sequences (see all 605):

    BE514981 CA393931 BM564499 CD367656 CD519276 AF425606 BU501603 AK124858 
    BE903851 BM744612 CK819750 CR616988 AF401233 BX332153 AI468821 BG032364 
    CR603314 CR616042 CN482016 BM757770 BQ420423 CR600893 BM673135 BI831224 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CELF6    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16
    SP1:                          -                                                                           
    SP2:                                                                                                      
    SP3:                    -     -           -                                                               
    SP4:                    -     -     -     -                                                               


    ECgene alternative splicing isoforms for CELF6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CELF6 expression in normal human tissues (normalized intensities)      CELF6 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCAGATAGTA
    CELF6 Expression
    About this image


    CELF6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)    fully expand to see all 19 entries
             Thalamus
             Septum   
    CELF6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CELF6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.348342

    UniProtKB/Swiss-Prot: CELF6_HUMAN, Q96J87
    Tissue specificity: Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower
    levels. Also expressed in fetal kidney

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CELF6 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Celf65 CUGBP, Elav-like family member 6   --   9 (32.02 cM) 59577917 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    74(a)
    1 → many
    10(1107487-1118370)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    77(a)
    1 → many
    GL343490.1(1292-14755)
    zebrafish
    (Danio rerio)
    Actinopterygii CELF66
    CUGBP, Elav-like family member 6
    69(a)
    1 → many
    18(625735-628511) ENSDARG00000096261
    fruit fly
    (Drosophila melanogaster)
    Insecta bru-36
    bruno-3
    55(a)
    1 → many
    3L(13515293-13796500)
    worm
    (Caenorhabditis elegans)
    Secernentea unc-756
    Protein UNC-75 (unc-75) mRNA, complete cds
    47(a)
    1 → many
    I(11592302-11601605) WBGene00006807
    soybean
    (Glycine max)
    eudicotyledons 467550672   -- 72.01(n)  


    ENSEMBL Gene Tree for CELF6 (if available)
    TreeFam Gene Tree for CELF6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CELF6 gene
    CELF12  CELF42  CELF22  CELF32  CELF52  ENSG000002730252  
    8 SIMAP similar genes for CELF6 using alignment to 3 protein entries:     CELF6_HUMAN (see all proteins):
    TNRC4    CELF3    BRUNOL4    CELF4    CELF5    CELF1
    CELF2    ELAVL2

    CELF6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CELF6 (see all 637)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1809306501,2
    --72576697(+) AGGTAC/GTCTCA 3 -- ds50010--------
    rs71798881,2
    C,A--72576721(+) AGACCC/TTCTAT 3 -- ds50010--------
    rs1862240711,2
    --72576806(+) GACACA/GTAGCA 3 -- ds50010--------
    rs1906962651,2
    --72576875(+) GGTGCA/GGGTAC 3 -- ds50010--------
    rs756449601,2
    F--72576953(+) CTCTGG/CTTCTT 3 -- ds50011Minor allele frequency- C:0.01NA 120
    rs287335461,2
    C--72577125(+) CCCCCA/CCCCCC 3 -- ut311Minor allele frequency- C:0.00NA 2
    rs1816015691,2
    --72577278(+) AAATAC/TGTGCA 3 -- ut310--------
    rs29122101,2
    --72577325(+) GGTGAC/GTCATG 3 -- ut31 ese30--------
    rs1905440521,2
    --72577503(+) TTAAGC/TACATG 3 -- ut310--------
    rs756577601,2
    C,F--72577554(+) ATGAAG/TAAGTA 3 -- ut311Minor allele frequency- T:0.07EA 120

    HapMap Linkage Disequilibrium report for CELF6 (72577068 - 72612525 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for CELF6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1601CNV Loss18451855

    Human Gene Mutation Database (HGMD): CELF6
    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612681    OMIM disorders: --

    4 diseases for CELF6:    About MalaCards
    bovine spongiform encephalopathy    choroiditis    cerebritis    neuronitis

    1 disease from the University of Copenhagen DISEASES database for CELF6:
    Bovine spongiform encephalopathy

    CELF6 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CELF6

    Export disorders for CELF6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CELF6 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with CELF6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. (PubMed id 10893231)1, 2, 3 Good P.J.... Herring D.C. (J. Biol. Chem. 2000)
    2. CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing. (PubMed id 14761971)1, 2, 9 Ladd A.N.... Cooper T.A. (J. Biol. Chem. 2004)
    3. The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. (PubMed id 23407934)1 Dougherty J.D....Heintz N. (J. Neurosci. 2013)
    4. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    5. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (BMC Med. Genet. 2007)
    6. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)2 Zody M.C....Nusbaum C. (Nature 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Expressed sequence tag analysis of human RPE/choroid for the NEIBank project: over 6000 non-redundant transcripts, novel genes and splice variants. (PubMed id 12107410)1 Wistow G.... Peterson K. (Mol. Vis. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
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      Query String
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    OMIM
    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 60677 HGNC: 14059 AceView: HEXAandBRUNOL6 Ensembl:ENSG00000140488 euGenes: HUgn60677
    ECgene: CELF6 H-InvDB: CELF6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CELF6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CELF6 gene:
    Search GeneIP for patents involving CELF6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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