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CELF5 Gene

protein-coding   GIFtS: 50
GCID: GC19P003224

CUGBP, Elav-Like Family Member 5

(Previous names: Bruno (Drosophila) -like 5, RNA binding protein, bruno-like...)
(Previous symbol: BRUNOL5)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CUGBP, Elav-Like Family Member 51 2     BRUNOL-52
BRUNOL51 2 3 5     Bruno-Like 5 RNA Binding Protein2
CELF-52 3     CUG-BP And ETR-3 Like Factor 52
RNA-Binding Protein BRUNOL-52 3     CUGBP Elav-Like Family Member 52
Bruno (Drosophila) -Like 5, RNA Binding Protein1     Bruno-Like Protein 53
Bruno-Like 5, RNA Binding Protein (Drosophila)1     CUG-BP- And ETR-3-Like Factor 53

External Ids:    HGNC: 140581   Entrez Gene: 606802   Ensembl: ENSG000001610827   OMIM: 6126805   UniProtKB: Q8N6W03   

Export aliases for CELF5 gene to outside databases

Previous GC identifer: GC19P002992


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CELF5 Gene:
This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition
motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and
third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved
in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene.
(provided by RefSeq, Jan 2012)

GeneCards Summary for CELF5 Gene:
CELF5 (CUGBP, Elav-like family member 5) is a protein-coding gene. GO annotations related to this gene include RNA binding and nucleotide binding. An important paralog of this gene is CELF1.

UniProtKB/Swiss-Prot: CELF5_HUMAN, Q8N6W0
Function: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon
inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated
alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart
remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites
flanking the alternative exon 5 of TNNT2 pre-mRNA




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NT_011295.12  NC_018930.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CELF5
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCELF5 promoter sequence
   Search Chromatin IP Primers for CELF5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CELF5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13

CELF5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CELF5 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P003224:  view genomic region     (about GC identifiers)

Start:
3,224,701 bp from pter      End:
3,297,074 bp from pter
Size:
72,374 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for CELF5

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CELF5_HUMAN, Q8N6W0 (See protein sequence)
Recommended Name: CUGBP Elav-like family member 5  
Size: 485 amino acids; 52355 Da
Sequence caution: Sequence=AAC27666.1; Type=Erroneous initiation; Sequence=AAK07476.1; Type=Erroneous termination;
Positions=482; Note=Translated as Gly; Sequence=BAD92304.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for CELF5:
2DNH (3D)    
Secondary accessions: D6W614 O75253 Q59GP2 Q86VW6 Q9BZC0 Q9NR86
Alternative splicing: 2 isoforms:  Q8N6W0-1   Q8N6W0-2   

Explore the universe of human proteins at neXtProt for CELF5: NX_Q8N6W0

Explore proteomics data for CELF5 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CELF5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001166144.1  NP_068757.2  

    ENSEMBL proteins: 
     ENSP00000292672   ENSP00000443498   ENSP00000335182   ENSP00000468503  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    2 InterPro protein domains:
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q8N6W0

    ProtoNet protein and cluster: Q8N6W0

    1 Blocks protein domain: IPB000504 RNA-binding region RNP-1 (RNA recognition motif)

    UniProtKB/Swiss-Prot: CELF5_HUMAN, Q8N6W0
    Similarity: Belongs to the CELF/BRUNOL family
    Similarity: Contains 3 RRM (RNA recognition motif) domains


    Find genes that share domains with CELF5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CELF5_HUMAN, Q8N6W0
    Function: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon
    inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated
    alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart
    remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites
    flanking the alternative exon 5 of TNNT2 pre-mRNA

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
         
    Find genes that share ontologies with CELF5           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CELF5:
     Synthetic lethal with Ras 

    Animal Models:
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    hsa-miR-142-5p hsa-miR-548j hsa-miR-548k hsa-miR-30d hsa-miR-218 hsa-miR-548l hsa-miR-30a hsa-miR-3622b-3p
    SwitchGear 3'UTR luciferase reporter plasmidCELF5 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CELF5_HUMAN, Q8N6W0: Nucleus (By similarity). Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus2
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with CELF5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CELF5
    Interactions:

        Search GeneGlobe Interaction Network for CELF5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for CELF5 (ENSP000002926724) via UniProtKB, MINT, STRING, and/or I2D (see all 35)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BECN1ENSP000003552314STRING: ENSP00000355231
    RAD54L2ENSP000003865204STRING: ENSP00000386520
    USO1ENSP000004116984STRING: ENSP00000411698
    RBFOX2ENSP000004130354STRING: ENSP00000413035
    RBPMS2ENSP000003000694STRING: ENSP00000300069
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006397mRNA processing IEA--

    Find genes that share ontologies with CELF5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CELF5



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CELF5 gene (2 alternative transcripts): 
    NM_001172673.1  NM_021938.3  

    Unigene Cluster for CELF5:

    CUGBP, Elav-like family member 5
    Hs.655747  [show with all ESTs]
    Unigene Representative Sequence: NM_001172673
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000292672(uc002lxm.3) ENST00000541430(uc010dtj.2 uc002lxl.2 uc002lxn.3)
    ENST00000334293(uc010xhg.2) ENST00000586050 ENST00000589370 ENST00000588350
    ENST00000588101 ENST00000591483
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate CELF5 (see all 35):
    hsa-miR-142-5p hsa-miR-548j hsa-miR-548k hsa-miR-30d hsa-miR-218 hsa-miR-548l hsa-miR-30a hsa-miR-3622b-3p
    SwitchGear 3'UTR luciferase reporter plasmidCELF5 3' UTR sequence
    Inhib. RNA
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CELF5
      QuantiTect SYBR Green Assays in human, mouse, rat CELF5
      QuantiFast Probe-based Assays in human, mouse, rat CELF5

    Additional mRNA sequence: 

    AB209067.1 AF248649.1 AF329266.1 AK294109.1 AL390161.1 AL832550.1 BC028101.1 BC047522.1 
    NR_033342.1 

    8 DOTS entries:

    DT.75101329  DT.410468  DT.100741331  DT.95351578  DT.40120248  DT.121420919  DT.100707212  DT.92070661 

    Selected AceView cDNA sequences (see all 66):

    AI696124 AW206025 AF248649 BE503640 AI474551 BI917050 AW770693 BQ186845 
    BU727417 AW149626 BX952381 BE327151 BI914168 AL832550 BC047522 BE258336 
    AA339334 AI671207 BE504949 BM683384 AW593725 AF329266 AL138002 NM_021938 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CELF5 (see all 7)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13a · 13b · 13c · 13d ^ 14 ^ 15
    SP1:                                                        -                 -     -                                   -     -         
    SP2:                                                        -                 -     -     -                                             
    SP3:                                            -           -                 -     -     -                                             
    SP4:                                                        -                 -     -     -                             -               
    SP5:                                                        -                                                                           


    ECgene alternative splicing isoforms for CELF5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CELF5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGTTTCAAC
    CELF5 Expression
    About this image


    CELF5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
    CELF5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CELF5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655747

    UniProtKB/Swiss-Prot: CELF5_HUMAN, Q8N6W0
    Tissue specificity: Expressed in brain

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for CELF5 gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Celf51 , 5 CUGBP, Elav-like family member 51, 5 88.95(n)1
    96.22(a)1
      10 (39.72 cM)5
    3195861  NM_176954.31  NP_795928.21 
     814592275 
    chicken
    (Gallus gallus)
    Aves BRUNOL51 bruno-like 5, RNA binding protein (Drosophila) 81.22(n)
    92.45(a)
      425867  XM_004948729.1  XP_004948786.1 
    lizard
    (Anolis carolinensis)
    Reptilia CELF56
    CUGBP, Elav-like family member 5
    81(a)
    1 ↔ 1
    AAWZ02038250(3966-12383)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia celf51 CUGBP, Elav-like family member 5 75.38(n)
    84.44(a)
      100036604  NM_001097170.1  NP_001090639.1 
    zebrafish
    (Danio rerio)
    Actinopterygii celf5a1 cugbp, Elav-like family member 5a 73.47(n)
    77.13(a)
      568052  NM_001130788.1  NP_001124260.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta bru-31 bruno-3 63.54(n)
    62.46(a)
      39527  NM_168557.3  NP_729923.1 
    worm
    (Caenorhabditis elegans)
    Secernentea unc-751 unc-75 57.85(n)
    58.16(a)
      182722  NM_060557.4  NP_492958.3 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G034571 AT1G03457 52.72(n)
    49.32(a)
      839497  NM_202023.6  NP_973752.1 
    rice
    (Oryza sativa)
    Liliopsida Os05g03734001 Os05g0373400 48.12(n)
    41.67(a)
      4338600  NM_001061902.1  NP_001055367.2 


    ENSEMBL Gene Tree for CELF5 (if available)
    TreeFam Gene Tree for CELF5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CELF5 gene
    CELF12  CELF42  CELF22  CELF32  CELF62  ENSG000002730252  
    8 SIMAP similar genes for CELF5 using alignment to 3 protein entries:     CELF5_HUMAN (see all proteins):
    TNRC4    CELF4    BRUNOL4    CELF3    CELF6    ELAVL2
    CELF1    CELF2

    Find genes that share paralogs with CELF5           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CELF5 (see all 1741)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1910916891,2
    C--2990264(+) TCTGTC/TGCCTA 1 -- us2k10--------
    rs1826084771,2
    --2990341(+) CCACCA/GCAGCC 1 -- us2k10--------
    rs1400199561,2
    C--2990355(+) GAGTAA/GCTGGG 1 -- us2k10--------
    rs1132027601,2
    C--3063349(+) AGAGA-/T/TT  
            
    TTTTT
    1 -- int11CSA 2
    rs16377981,2
    C--3147554(+) gcacaA/Gccatg 1 -- us2k12Minor allele frequency- G:0.00NA 4
    rs1865448461,2
    C--3147561(+) CATGCC/TTGGCT 1 -- us2k10--------
    rs40619301,2
    C--3220192(-) CTTGG-/T/TT  
            
    TTTTT
    1 -- int1 trp31NA 2
    rs1871095291,2
    --3222724(+) TTTTAA/CATGGG 2 -- us2k10--------
    rs1442469791,2
    --3222785(+) TGAGCA/GGTTTT 2 -- us2k10--------
    rs4266331,2
    C,F,A,H--3222856(-) ggatgC/Tgctct 2 -- us2k128Minor allele frequency- T:0.35NS EA NA WA CSA 2770

    HapMap Linkage Disequilibrium report for CELF5 (3224701 - 3297074 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for CELF5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509716CNV Insertion20534489
    esv2494686CNV Insertion19546169
    esv1699504CNV Insertion17803354
    esv1459053CNV Insertion17803354
    nsv509717CNV Insertion20534489
    dgv3648n71CNV Loss21882294
    nsv833712CNV Loss17160897
    dgv3649n71CNV Loss21882294
    nsv910722CNV Loss21882294
    nsv910723CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CELF5
    DNA2.0 Custom Variant and Variant Library Synthesis for CELF5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

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    OMIM gene information: 612680    OMIM disorders: --


    Find genes that share disorders with CELF5           About GenesLikeMe

    Genetic Association Database (GAD): CELF5

    Export disorders for CELF5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CELF5 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with CELF5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. (PubMed id 10893231)1, 2, 3 Good P.J.... Herring D.C. (J. Biol. Chem. 2000)
    2. The CELF family of RNA binding proteins is implicated in cell- specific and developmentally regulated alternative splicing. (PubMed id 11158314)1, 2 Ladd A.N.... Cooper T.A. (Mol. Cell. Biol. 2001)
    3. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    4. A genome-wide meta-analysis identifies novel loci associated with schizophrenia and bipolar disorder. (PubMed id 20889312)1 Wang K.S....Aragam N. (Schizophr. Res. 2010)
    5. Differential expression of the Brunol/CELF family genes during Xenopus laevis early development. (PubMed id 19757395)1 Wu J....Mao B. (Int. J. Dev. Biol. 2010)
    6. Genome-wide association study identifies variants associated with histologic features of nonalcoholic Fatty liver disease. (PubMed id 20708005)4 Chalasani N....Rotter J.I. (Gastroenterology 2010)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 60680 HGNC: 14058 AceView: BRUNOL5 Ensembl:ENSG00000161082 euGenes: HUgn60680
    ECgene: CELF5 H-InvDB: CELF5

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CELF5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for CELF5 gene:
    Search GeneIP for patents involving CELF5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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