CELF2 Gene
protein-coding GIFtS : 57 GCID: GC10 P011049
CUGBP, Elav-like family member 2 CUG triplet repeat, RNA-binding protein 2, CUG triplet... CUGBP2 )
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Aliasesfor CELF2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases CUGBP, Elav-Like Family Member 2 1 2 NAPOR2 3 BRUNOL31 2 3 5 CUG Triplet Repeat RNA-Binding Protein 22 3 CUGBP21 2 3 5 CUG-BP- And ETR-3-Like Factor 22 3 ETR32 3 5 ELAV-Type RNA-Binding Protein 32 3 CUG Triplet Repeat, RNA Binding Protein 21 2 HNAPOR1 Bruno-Like Protein 32 3 RNA-Binding Protein BRUNOL-32 3 Neuroblastoma Apoptosis-Related RNA-Binding Protein2 3 Etr-31 CELF-22 3 NAPOR-21 CUG-BP22 3 CUG Triplet Repeat, RNA-Binding Protein 21 ETR-32 3 CUGBP Elav-Like Family Member 22
Export aliases for CELF2 gene to outside databases Previous GC identifers: GC10P011048 GC10P010966
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Summariesfor CELF2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for CELF2 : Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. (provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: CELF2_HUMAN, O95319 Function : RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNAalternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Promotes inclusion of exonS 21 and exclusion of exon 5 of the NMDA receptor R1 pre-mRNA. Involved in the apoB RNA editing activity. Increases COX2 mRNA stability and inhibits COX2 mRNA translation in epithelial cells after radiation injury (By similarity). Modulates the cellular apoptosis program by regulating COX2-mediated prostaglandin E2 (PGE2) expression (By similarity). Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK. Binds to the muscle-specific splicing enhancer (MSE) intronic sites flanking the TNNT2 alternative exon 5. Binds preferentially to UG-rich sequences, in particular UG repeat and UGUU motifs. Binds to apoB mRNA, specifically to AU-rich sequences located immediatly upstream of the edited cytidine. Binds AU-rich sequences in the 3'-UTR of COX2 mRNA (By similarity). Binds to an intronic RNA element responsible for the silencing of exon 21 splicing (By similarity). Binds to (CUG)n repeats (By similarity) Gene Wiki entry for CELF2 (CUGBP2)
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Genomic Viewsfor CELF2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000010.10 NC_018921.1 NT_008705.16 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for CELF2 Other transcription factors Search SABiosciences Chromatin IP Primers for CELF2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10p13 Ensembl cytogenetic band: 10p14 HGNC cytogenetic band: 10p13 CELF2 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10P011049: view genomic region
(about GC identifiers )
Start: 11,047,259 bp from pter End:
11,378,674 bp from pter
Size: 331,416 bases Orientation:
plus strand
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Proteinsfor CELF2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: CELF2_HUMAN, O95319 See
protein sequence )Recommended Name: Size : 508 amino acids; 54285 DaSubunit : Interacts with A1CF (By similarity)Subcellular location : Nucleus. Cytoplasm. Note=Accumulates in the cytoplasm after ionizing radiation (By similarity).Colocalizes with APOBEC1 and A1CF. RNA-binding activity is detected in both nuclear and cytoplasmic compartments
Developmental stage : Isoform 1 is expressed in fetal brain. Isoform 2 is expressed in fetal heart, brain, thymus, lung,liver, skeletal muscle, kidney and spleen. Isoform 4 is expressed in fetal heart, brain, thymus, lung and skeletal muscle
Secondary accessions : B7ZAN9 Q7KYU4 Q8N499 Q92950 Q96NW9 Q96RQ5 Q96RQ6 Q9UL67Alternative splicing : 5 isoforms : O95319-1 O95319-2 O95319-3 O95319-4 O95319-5 Explore the universe of human proteins at neXtProt for CELF2: NX_O95319 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_O95319 CELF2 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (4 alternative transcripts): NP_001020247.1 NP_001020248.1 NP_001077060.1 NP_006552.3 ENSEMBL proteins: ENSP00000315328 ENSP00000346426 ENSP00000346971 ENSP00000368563 ENSP00000406451 ENSP00000389951 ENSP00000443926 ENSP00000382743 ENSP00000404834 ENSP00000388530 ENSP00000438884 Human Recombinant Protein Products: Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing CELF2 Antibody Products: Assay Products for CELF2:
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Protein
Domains /for CELF2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry O95319 ProtoNet protein and cluster: O95319
1 Blocks protein family : IPB000504 UniProtKB/Swiss-Prot: CELF2_HUMAN, O95319 Similarity : Belongs to the CELF/BRUNOL familySimilarity : Contains 3 RRM (RNA recognition motif) domains
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Functionfor CELF2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: CELF2_HUMAN, O95319 Function : RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNAalternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in embryonic, but not adult, skeletal muscle. Activates TNNT2 exon 5 inclusion by antagonizing the repressive effect of PTB. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Promotes inclusion of exonS 21 and exclusion of exon 5 of the NMDA receptor R1 pre-mRNA. Involved in the apoB RNA editing activity. Increases COX2 mRNA stability and inhibits COX2 mRNA translation in epithelial cells after radiation injury (By similarity). Modulates the cellular apoptosis program by regulating COX2-mediated prostaglandin E2 (PGE2) expression (By similarity). Binds to (CUG)n triplet repeats in the 3'-UTR of transcripts such as DMPK. Binds to the muscle-specific splicing enhancer (MSE) intronic sites flanking the TNNT2 alternative exon 5. Binds preferentially to UG-rich sequences, in particular UG repeat and UGUU motifs. Binds to apoB mRNA, specifically to AU-rich sequences located immediatly upstream of the edited cytidine. Binds AU-rich sequences in the 3'-UTR of COX2 mRNA (By similarity). Binds to an intronic RNA element responsible for the silencing of exon 21 splicing (By similarity). Binds to (CUG)n repeats (By similarity)
Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 14 )human mouse rat see all 4 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 4 ): CELF2 (NM_001025077 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CELF2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CELF2
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELF2
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0000166 nucleotide binding
IEA -- GO:0003723 RNA binding
IEA --
About GeneDecksing 1 GenomeRNAi human phenotype for CELF2 :
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Pathways & Interactionsfor CELF2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways About this table See pathways by source Super-pathway contained gene-specific pathways 1 mRNA Splicing - Major Pathway
1 Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CELF2 STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)5 Interacting proteins for CELF2 (O95319 2 , 3 ENSP00000389951 4 via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 4 biological process terms (GO ID links to tree view) : About this table
About GeneDecksing
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Drugs & Compoundsfor CELF2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Browse Tocris compounds for CELF2 2 HMDB Compounds for CELF2 About this table 1 Novoseek chemical compound relationship for CELF2 gene About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
iron
6.11
1
7585245 (1)
CELF2
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Transcriptsfor CELF2 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for CELF2 gene (4 alternative transcripts): NM_001025076.2 NM_001025077.2 NM_001083591.1 NM_006561.3 Unigene Cluster for CELF2:
CUGBP, Elav-like family member 2 Hs.309288 [show with all ESTs ] Unigene Representative Sequence: NM_001025077 11 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000315874 (uc010qbk.1 uc010qbm.1 ) ENST00000354440 (uc001ikk.2 uc010qbl.1 uc010qbp.1 )ENST00000354897 ENST00000379261 (uc010qbi.2 uc010qbj.1 uc001iki.4 )ENST00000416382 ENST00000450189 (uc001ikl.4 ) ENST00000542579 ENST00000399850 (uc010qbo.1 )ENST00000417956 (uc009xiw.1 ) ENST00000427450 (uc001iko.4 uc001ikp.4 )ENST00000537122 Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 14 )human mouse rat see all 4 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 4 ): CELF2 (NM_001025077 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CELF2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CELF2
Additional cDNA sequence: AF036956.1 AF086447.1 AF090693.1 AF090694.1 AF432906.1 AK293164.1 AK295511.1 AK297313.1 AK297380.1 AK299548.1 AK299983.1 AK299992.1 AK302681.1 AK304216.1 AK310038.1 AK314087.1 AK316354.1 BC036391.1 BC050635.1 BX647703.1 CR936676.1 U69546.1
24/33 DOTS entries (see all 33 ): DT.444499 DT.101960230
DT.95074009 DT.97819078 DT.95255913 DT.100030160 DT.91750926 DT.101969833 DT.121262991 DT.91653315 DT.100823247 DT.121263174 DT.216871 DT.97855182 DT.121263144 DT.216872 DT.91750927 DT.121262966 DT.121263151 DT.121263069 DT.40117190 DT.91833505 DT.92058076 DT.100823254 24/451 AceView cDNA sequences (see all 451 ):
BU736216 BM473904 AI783598 BX643214 BX483433 BM699598 BF510414 AI064950 W70053 BM671832 AL133765 AA670420 BE894472 AI707797 BQ718002 AA744702 AA403114 BM719338 BM667569 BM680801 AA450229 AA213736 AI655910 AW070500 GeneLoc Exon Structure 5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CELF2 (see all 8 ) About this scheme ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b · 18c ^ 19 SP1 : - - - - - - - - - SP2 : - - - - - - - SP3 : - - - - - - - - - - SP4 : - - - - - - - SP5 : - - - -
ECgene alternative splicing isoforms for CELF2
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Expression for CELF2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section CELF2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAACGTTTCT
About this image CELF2 expression in embryonic tissues and stem cells About this table See CELF2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CELF2 SOURCE GeneReport for Unigene cluster: Hs.309288 UniProtKB/Swiss-Prot: CELF2_HUMAN, O95319 Tissue specificity : Expressed in frontal cortex. Isoform 1 is expressed in brain and lung. Isoform 2 is expressed inheart, brain, placenta, lung, liver, kidney, skeletal muscle and pancreas. Isoform 4 is expressed in heart, lung, skeletal muscle, kidney and pancreas SABiosciences Custom PCR Arrays for CELF2 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CELF2
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Orthologsfor CELF2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for CELF2 gene from 8/27 species (see all 27 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves CELF21
CUGBP, Elav-like family member 2
90.15(n) 98.97(a)
374111 NM_204260.1 NP_989591.1
lizard Reptilia CELF26
--
98(a)
1 ↔ 1
5(5673301-5753670)
African clawed frog Amphibia U69547.12
--
86.85(n)
U69547.1
zebrafish Actinopterygii AB050496.12
--
79.96(n)
373117 AB050496.1
fruit fly Insecta aret1
arrest
55.76(n) 56.82(a)
34648 NM_165003.2 NP_723738.1
worm Secernentea etr-16
ELAV-Type RNA binding protein family member (etr-1... 34(a)
1 → many
II(162374-170628)
thale cress eudicotyledons AT1G034571
RNA recognition motif-containing protein
42.95(n) 33.07(a)
839497 NM_100228.8 NP_171845.2
rice Liliopsida Os05g03734001
hypothetical protein
47.73(n) 42.27(a)
4338600 NM_001061902.1 NP_001055367.2
ENSEMBL Gene Tree for CELF2 (if available)TreeFam Gene Tree for CELF2 (if available)
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Paralogsfor CELF2 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for CELF2 gene CELF1 2 CELF4 2 CELF3 2 CELF6 2 CELF5 2 10 SIMAP similar genes for CELF2 using alignment to 4 protein entries: CELF2_HUMAN (see all proteins ):CELF1 TNRC4 CELF3 CELF6 CELF4 RBMS2 BRUNOL6 CELF5 HNRNPA1 RBM4B About GeneDecksing
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Genomic Variantsfor CELF2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 10 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for CELF2 (11047259 - 11297259 bp, first 250kb of CELF2)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 12 variations for CELF2 9 CNVs 75099 85103 70921 1217 85104 75097 85102 1872 75098 3 Indels 24326 100865 75100
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor CELF2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 602538
OMIM disorders : --18 : About MalaCards arrhythmogenic right ventricular dysplasia childhood absence epilepsy absence epilepsy neuroblastoma myotonic dystrophy oral leukoplakia leukoplakia differentiating neuroblastoma conduct disorder squamous cell carcinoma adhd alzheimer's disease colon cancer breast cancer ataxia schizophrenia carcinoma malaria 2 Novoseek disease relationships for CELF2 gene About this table
Disease
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
myotonic dystrophy
52.1
1
9887331 (1)
tumors
0
1
15489060 (1)
Human Genome Epidemiology (HuGE) Navigator: CELF2 (0 documents) Export disorders for CELF2 gene to outside databases
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Publicationsfor CELF2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for CELF2 gene, integrated from 9 sources (see all 62 ):(articles sorted by number of sources associating them with CELF2) Utopia : connect your pdf to the dynamic
Genomic organization and isoform-specific tissue expression of human NAPOR (CUGBP2) as a candidate gene for familial arrhythmogenic right ventricular dysplasia. (PubMed id 11414768) 1 , 2 , 9(2001) Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy. (PubMed id 9887331) 1 , 3, 9(1999) Identification of CELF splicing activation and repression domains in vivo. (PubMed id 15894795) 1 , 2 , 9(2005) Developmentally-regulated expression of mNapor encoding an apoptosis- induced ELAV-type RNA binding protein. (PubMed id 10524244) 1 , 2 , 9(1999) A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator. (PubMed id 10893231) 1 , 2 , 9(2000) ETR-3 and CELF4 protein domains required for RNA binding and splicing activity in vivo. (PubMed id 14973222) 1 , 2 (2004) The CELF family of RNA binding proteins is implicated in cell- specific and developmentally regulated alternative splicing. (PubMed id 11158314) 1 , 2 (2001) Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor. (PubMed id 11577082) 1 , 2 (2001) Single pass sequencing of a unidirectional human fetal heart cDNA library to discover novel genes of the cardiovascular system. (PubMed id 7869393) 1 , 3(1994) Fluorescent differential display analysis of gene expression in apoptotic neuroblastoma cells. (PubMed id 9858671) 2 , 9(1998)
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External Searches for CELF2 gene
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miRBase ,
ECgene ,
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and/or
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Specialized Databases showing CELF2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for CELF2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for CELF2 gene: CELF2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor CELF2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for CELF2 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for CELF2 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for CELF2 OriGene 3'-UTR Clone for CELF2 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for CELF2 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CELF2 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CELF2
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Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
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