Aliases for CELA2B Gene
External Ids for CELA2B Gene
Previous GeneCards Identifiers for CELA2B Gene
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2B is secreted from the pancreas as a zymogen. In other species, elastase 2B has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, Jul 2008]
GeneCards Summary for CELA2B Gene
CELA2B (Chymotrypsin Like Elastase Family Member 2B) is a Protein Coding gene. Among its related pathways are Pancreatic secretion and Protein digestion and absorption. GO annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is CELA3A.
UniProtKB/Swiss-Prot for CELA2B Gene
Acts upon elastin.