Aliases for CELA1 Gene
External Ids for CELA1 Gene
Previous Symbols for CELA1 Gene
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, pancreatic elastase 1 is not expressed in the pancreas. To date, elastase 1 expression has only been detected in skin keratinocytes. Clinical literature that describes human elastase 1 activity in the pancreas or fecal material is actually referring to chymotrypsin-like elastase family, member 3B. [provided by RefSeq, May 2009]
GeneCards Summary for CELA1 Gene
CELA1 (Chymotrypsin-Like Elastase Family, Member 1) is a Protein Coding gene. Diseases associated with CELA1 include pancreatic steatorrhea and steatorrhea. GO annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is CELA2B.
UniProtKB/Swiss-Prot for CELA1 Gene
Acts upon elastin