External Ids for CECR2 Gene
Previous GeneCards Identifiers for CECR2 Gene
This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
GeneCards Summary for CECR2 Gene
CECR2 (Cat Eye Syndrome Chromosome Region, Candidate 2) is a Protein Coding gene. Diseases associated with CECR2 include Cat Eye Syndrome and Chromosome 22Q11.2 Microduplication Syndrome. An important paralog of this gene is KAT2A.
UniProtKB/Swiss-Prot for CECR2 Gene
Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis.