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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CECR2 Gene

protein-coding   GIFtS: 49
GCID: GC22P017840

Cat Eye Syndrome Chromosome Region, Candidate 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cat Eye Syndrome Chromosome Region, Candidate 21 2
KIAA17403 5
Cat Eye Syndrome Critical Region Protein 22

External Ids:    HGNC: 18401   Entrez Gene: 274432   Ensembl: ENSG000000999547   OMIM: 6075765   UniProtKB: Q9BXF33   

Export aliases for CECR2 gene to outside databases

Previous GC identifers: GC22P014900 GC22P016331 GC22P016328 GC22U900292 GC22P001668


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CECR2 Gene: 
CECR2 (cat eye syndrome chromosome region, candidate 2) is a protein-coding gene. Diseases associated with CECR2 include 22q11.2 duplication, and coloboma of iris. GO annotations related to this gene include protein binding and nucleosome-dependent ATPase activity. An important paralog of this gene is BAZ1A.

UniProtKB/Swiss-Prot: CECR2_HUMAN, Q9BXF3
Function: Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of
chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the
integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription,
chromosome remodeling and cytokinesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000022.10  NC_018933.2  NT_011519.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CECR2 gene promoter:
         p300   ATF-2   HNF-1A   Meis-1b   PPAR-alpha   PPAR-gamma1   HNF-1   Meis-1a   PPAR-gamma2   Meis-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for CECR2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CECR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q11.2   Ensembl cytogenetic band:  22q11.1   HGNC cytogenetic band: 22q11.2

CECR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CECR2 gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P017840:  view genomic region     (about GC identifiers)

Start:
17,840,837 bp from pter      End:
18,033,845 bp from pter
Size:
193,009 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CECR2_HUMAN, Q9BXF3 (See protein sequence)
Recommended Name: Cat eye syndrome critical region protein 2  
Size: 1484 amino acids; 164213 Da
Subunit: Part of the CECR2-containing remodeling factor (CERF) complex which contains CECR2 and SMARCA1. Interacts
with acetylated lysine residues on histone H2A and H3 (in vitro). Interacts with LRPPRC
Miscellaneous: Candidate gene for the Cat Eye Syndrome (CES), a developmental disorder associated with the
duplication of a 2 Mb region of 22q11.2. Duplication usually takes in the form of a surpernumerary bisatellited
isodicentric chromosome, resulting in four copies of the region (represents an inv dup(22)(q11)). CES is
characterized clinically by the combination of coloboma of the iris and anal atresia with fistula, downslanting
palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and
normal or near-normal mental development
Sequence caution: Sequence=CAH56122.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=CAH56212.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=EAW57756.1;
Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for CECR2:
3NXB (3D)    
Secondary accessions: A8MS90 A8MX16 Q658Z4 Q96P58 Q9C0C3
Alternative splicing: 3 isoforms:  Q9BXF3-1   Q9BXF3-2   Q9BXF3-3   

Explore the universe of human proteins at neXtProt for CECR2: NX_Q9BXF3

Explore proteomics data for CECR2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BXF3

  • CECR2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CECR2 Protein Expression
    REFSEQ proteins: NP_113601.2  
    ENSEMBL proteins: 
     ENSP00000383428   ENSP00000383417   ENSP00000347357   ENSP00000262608   ENSP00000341219  

    Human Recombinant Protein Products for CECR2: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for CECR2 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA12762840
    GO:0005719nuclear euchromatin IEA--
    GO:0090537CERF complex IDA15640247

    CECR2 for ontologies           About GeneDecksing



    CECR2 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for CECR2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR018359 Bromodomain_CS
     IPR001487 Bromodomain

    Graphical View of Domain Structure for InterPro Entry Q9BXF3

    ProtoNet protein and cluster: Q9BXF3

    1 Blocks protein domain: IPB001487 Bromodomain signature

    UniProtKB/Swiss-Prot: CECR2_HUMAN, Q9BXF3
    Similarity: Contains 1 bromo domain


    CECR2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CECR2_HUMAN, Q9BXF3
    Function: Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of
    chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the
    integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription,
    chromosome remodeling and cytokinesis

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12762840
         
    CECR2 for ontologies           About GeneDecksing


    Phenotypes:
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Cecr2):
     craniofacial  embryogenesis  hearing/vestibular/ear  mortality/aging  nervous system 
     vision/eye 

    CECR2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cecr2tm1.1Hemc for CECR2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CECR2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CECR2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CECR2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CECR2 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CECR2
    8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate CECR2 (see all 67):
    hsa-miR-548j hsa-miR-3607-3p hsa-miR-4272 hsa-miR-219-5p hsa-miR-30d hsa-miR-4267 hsa-miR-30a hsa-miR-508-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of CECR2

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CECR2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CECR2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for CECR2 (Q9BXF33 ENSP000002626084) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LRPPRCP427043, ENSP000002606654I2D: score=2 STRING: ENSP00000260665
    UXTQ9UBK93, ENSP000003373934I2D: score=1 STRING: ENSP00000337393
    SMARCA5ENSP000002831314STRING: ENSP00000283131
    MYCENSP000003672074STRING: ENSP00000367207
    About this table

    Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000910cytokinesis NAS11827465
    GO:0001842neural fold formation IEA--
    GO:0001843neural tube closure IEA--
    GO:0006309apoptotic DNA fragmentation TAS12762840
    GO:0007010cytoskeleton organization NAS11827465

    CECR2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CECR2

    Search CenterWatch for drugs/clinical trials and news about CECR2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CECR2 gene: 
    NM_031413.3  

    Unigene Cluster for CECR2:

    Cat eye syndrome chromosome region, candidate 2
    Hs.658723  [show with all ESTs]
    Unigene Representative Sequence: NM_031413
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000400585 ENST00000497534 ENST00000400573 ENST00000355219 ENST00000262608(uc010gqv.1 uc010gqw.1 uc002zml.2 uc002zmo.2)
    ENST00000342247(uc002zmm.1 uc002zmn.3)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CECR2
    8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate CECR2 (see all 67):
    hsa-miR-548j hsa-miR-3607-3p hsa-miR-4272 hsa-miR-219-5p hsa-miR-30d hsa-miR-4267 hsa-miR-30a hsa-miR-508-5p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CECR2
    Clone
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    OriGene clones in human, mouse for CECR2 (see all 7)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CECR2
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                         Customized lentivirus expression plasmids for stable overexpression of CECR2 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for CECR2
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CECR2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CECR2

    Additional mRNA sequence: 

    AB051527.1 AF411609.1 AK091754.1 AK308330.1 AL832377.1 BX647449.1 

    6 DOTS entries:

    DT.99950613  DT.102667  DT.97762450  DT.100018803  DT.95323559  DT.102827713 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CECR2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^ 19a · 19b
    SP1:                                                                          -                                   -                     
    SP2:                                      -                                                                                             
    SP3:                                                                                                                                    


    ECgene alternative splicing isoforms for CECR2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CECR2 expression in normal human tissues (normalized intensities)      CECR2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CECR2 Expression
    About this image


    CECR2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/31 selected tissues (see all 31) fully expand
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Uterus
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 5 entries
             XY Germ Cells Testis Cord
             seminal vesicle ; glandular cells   
     
     Colon (Gastrointestinal Tract)    fully expand to see all 4 entries
             colon ; peripheral nerve/ganglion   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex

    See CECR2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CECR2

    SOURCE GeneReport for Unigene cluster: Hs.658723

    UniProtKB/Swiss-Prot: CECR2_HUMAN, Q9BXF3
    Tissue specificity: Highly expressed in skeletal muscle, thymus, placenta and lung. Expressed at lower level in
    brain, heart, colon, spleen, kidney

        SABiosciences Custom PCR Arrays for CECR2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CECR2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CECR2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cecr21 , 5 cat eye syndrome chromosome region, candidate 2 homolog more5
    cat eye syndrome chromosome region, candidate 21
    83.39(n)1
    82.43(a)1
      6 (56.97 cM)5
    3304091  NM_001128151.11  NP_001121623.11 
     1206663695 
    chicken
    (Gallus gallus)
    Aves CECR21 cat eye syndrome chromosome region, candidate 2 73.04(n)
    72.91(a)
      418161  NM_001130739.1  NP_001124211.1 
    lizard
    (Anolis carolinensis)
    Reptilia CECR26
    cat eye syndrome chromosome region, candidate 2
    62(a)
    1 ↔ 1
    5(13878172-13984624)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7999181 uncharacterized LOC799918 52.85(n)
    47.61(a)
      799918  XM_002666820.2  XP_002666866.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta dikar6
    dikar
    11(a)
    1 ↔ 1
    3L(6721900-6736264)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SPT7(YBR081C)4 Subunit of the SAGA transcriptional regulatory complex, more   --   2(405251-401253) 852373  NP_009637.1 


    ENSEMBL Gene Tree for CECR2 (if available)
    TreeFam Gene Tree for CECR2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CECR2 gene
    BAZ1A2  BPTF2  BAZ2B2  BAZ2A2  BAZ1B2  KAT2A2  KAT2B2  
    3 SIMAP similar genes for CECR2 using alignment to 6 protein entries:     CECR2_HUMAN (see all proteins):
    AURA2    BRD4    BRDT

    CECR2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4729 SNPs in CECR2 are shown (see all 4729)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1821999951,2
    --1666624(+) TCGGCC/TTCCCA 1 -- us2k10--------
    rs2001418831,2
    C--1666651(+) GGCGT-/AAGCCA 1 -- us2k10--------
    rs733917511,2
    C--1666748(+) ACCTCG/CTTCAG 1 -- us2k14Minor allele frequency- C:0.09WA NA EA 360
    rs1117428371,2
    C,F--1666759(+) GTTACG/ATGACA 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs1868066521,2
    --1666767(+) ACAATG/TCCGGG 1 -- us2k10--------
    rs1506466791,2
    --1666772(+) TCCGGG/TGTGGC 1 -- us2k10--------
    rs1396672591,2
    C--1666945(+) TAAATC/TATCAA 1 -- us2k10--------
    rs1419647441,2
    --1666966(+) GGAATC/GAAAGA 1 -- us2k10--------
    rs1463905271,2
    --1667020(+) GGGGCA/GGAGGA 1 -- us2k10--------
    rs1173999341,2
    C,F--1667024(+) CGGAGG/AAGACC 1 -- us2k11Minor allele frequency- A:0.02NA 120

    HapMap Linkage Disequilibrium report for CECR2 (17840837 - 18033845 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/14 variations for CECR2 (see all 14):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2663280CNV Deletion23128226
    esv2667610CNV Deletion23128226
    nsv820372CNV Deletion20802225
    nsv9871CNV Loss18304495
    nsv438324CNV Loss16468122
    nsv3553CNV Loss18451855
    nsv914150CNV Loss21882294
    nsv512644CNV Loss21212237
    nsv834118CNV Loss17160897
    nsv510802CNV Loss20534489

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607576    OMIM disorders: --

    6 diseases for CECR2:    About MalaCards
    22q11.2 duplication    coloboma of iris    coloboma    velocardiofacial syndrome
    digeorge syndrome    spina bifida

    2 diseases from the University of Copenhagen DISEASES database for CECR2:
    Coloboma     Velocardiofacial syndrome

    CECR2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CECR2
    Human Genome Epidemiology (HuGE) Navigator: CECR2 (1 document)

    Export disorders for CECR2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CECR2 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with CECR2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Analysis of the cat eye syndrome critical region in humans and the region of conserved synteny in mice: a search for candidate genes at or near the human chromosome 22 pericentromere. (PubMed id 11381032)1, 2, 3 Footz T.K....McDermid H.E. (2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L. (PubMed id 15640247)1, 2 Banting G.S.... Shiekhattar R. (2005)
    4. Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity. (PubMed id 11827465)1, 2 Liu L. and McKeehan W.L. (2002)
    5. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970)1, 2 Nagase T.... Ohara O. (2000)
    6. Functional genomics identifies therapeutic targets for MYC-driven cancer. (PubMed id 22623531)1 Toyoshima M....Grandori C. (2012)
    7. A 600 kb triplication in the cat eye syndrome critical region causes anorectal, renal and preauricular anomalies in a three-generation family. (PubMed id 22395867)1 Knijnenburg J....van Zutven L.J. (2012)
    8. Genome-wide screen of human bromodomain-containing pro teins identifies Cecr2 as a novel DNA damage response protein. (PubMed id 22699752)1 Lee S.K....Kwon J. (2012)
    9. CECR2 is involved in spermatogenesis and forms a compl ex with SNF2H in the testis. (PubMed id 22154806)1 Thompson P.J....McDermid H.E. (2012)
    10. Histone recognition and large-scale structural analysis of the human bromodomain family. (PubMed id 22464331)2 Filippakopoulos P.... Knapp S. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27443 HGNC: 1840 Ensembl:ENSG00000099954 euGenes: HUgn27443 ECgene: CECR2
    H-InvDB: CECR2

    (According to HUGE)
    About This Section
    HUGE: KIAA1740

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CECR2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CECR2 gene:
    Search GeneIP for patents involving CECR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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