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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CEBPZ Gene

protein-coding GIFtS: 54
GCID: GC02M037428

CCAAT/enhancer binding protein (C/EBP), zeta

Explore 17 diseases affiliated with
CEBPZ via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
CCAAT/Enhancer Binding Protein (C/EBP), Zeta¹ ²		NOC1² ⁵
CBF2¹ ² ³		CTF2¹
CBF² ³ ⁵		HSP-CBF²
CCAAT-Binding Factor² ³		CCAAT/Enhancer Binding Protein Zeta²
CCAAT-Box-Binding Transcription Factor² ³		CCAAT/Enhancer-Binding Protein Zeta²

External Ids:	HGNC: 24218¹	Entrez Gene: 10153²	Ensembl: ENSG00000115816⁷	OMIM: 612828⁵	UniProtKB: Q03701³

Export aliases for CEBPZ gene to outside databases

Previous GC identifers: GC02M037403 GC02M037340 GC02M037168

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CEBPZ_HUMAN, Q03701

Function: Stimulates transcription from the HSP70 promoter

Gene Wiki entry for CEBPZ (CCAAT/enhancer binding protein zeta)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000002.11 NC_018913.1 NT_022184.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CEBPZ gene promoter:
Oct-B1 p53 CUTL1 FOXO3b HNF-1A Evi-1 AREB6 POU2F1 HNF-1 POU2F1a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CEBPZ promoter sequence

Search SABiosciences Chromatin IP Primers for CEBPZ

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEBPZ

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p22.2 Ensembl cytogenetic band: 2p22.2 HGNC cytogenetic band: 2p22.3

CEBPZ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEBPZ gene location

GeneLoc information about chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M037428: view genomic region (about GC identifiers)

Start:	37,428,755 bp from pter	End:	37,458,856 bp from pter
Size:	30,102 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CEBPZ_HUMAN, Q03701 (See protein sequence)

Recommended Name: CCAAT/enhancer-binding protein zeta

Size: 1054 amino acids; 120974 Da

Subcellular location: Nucleus

Sequence caution: Sequence=AAA51924.1; Type=Frameshift; Positions=998;

Secondary accessions: Q8NE75

Explore the universe of human proteins at neXtProt for CEBPZ: NX_Q03701

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q03701

CEBPZ Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_005751.2

ENSEMBL proteins:

ENSP00000234170 ENSP00000391881

Human Recombinant Protein Products for CEBPZ:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Novus Biologicals CEBPZ Lysate
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	Browse Proteins at Uscn

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

CEBPZ for ontologies About GeneDecksing

CEBPZ Antibody Products:

	EMD Millipore Mono- and Polyclonal Antibodies for the study of CEBPZ
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Assay Products for CEBPZ:

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	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CEBPZ for domains About GeneDecksing

2 InterPro domains/families:

IPR005612 CCAAT-binding_factor

IPR016024 ARM-type_fold

Graphical View of Domain Structure for InterPro Entry Q03701

ProtoNet protein and cluster: Q03701

1 Blocks protein family: IPB005612 CBF/Mak21 family

UniProtKB/Swiss-Prot: CEBPZ_HUMAN, Q03701

Similarity: Belongs to the CBF/MAK21 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: CEBPZ_HUMAN, Q03701

Function: Stimulates transcription from the HSP70 promoter

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	TAS	2247079

CEBPZ for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for CEBPZ:

Synthetic lethal with Ras

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CEBPZ

miRNA Products:		OriGene 3'-UTR Clone: CEBPZ Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CEBPZ
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate CEBPZ:
		hsa-miR-206 hsa-miR-613 hsa-miR-1
		SwitchGear 3'UTR luciferase reporter plasmid: CEBPZ 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CEBPZ (see all 7) OriGene shRNA RFP: CEBPZ OriGene siRNA: CEBPZ
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		Sirion Biotech Custom design and validation of potent shRNA sequences against CEBPZ

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for CEBPZ
			Sirion Biotech Customized adenovirus for overexpression of CEBPZ Sirion Biotech Customized adenovirus for potent knockdown of CEBPZ

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEBPZ (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEBPZ OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CEBPZ (NM_005760)
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CEBPZ
		Search LifeMap BioReagents cell lines for CEBPZ
		Sirion Biotech Customized stable knockdown cell line services for CEBPZ Sirion Biotech Customized inducible knockdown cell line services for CEBPZ Sirion Biotech Customized stable overexpressing cell line services for CEBPZ Sirion Biotech Customized inducible overexpressing cell line services for CEBPZ

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEBPZ

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Direct p53 effectors

Direct p53 effectors

1.00

1 BioSystems Pathway for CEBPZ

Direct p53 effectors

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for CEBPZ

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/150 Interacting proteins for CEBPZ (Q03701^{2, 3} ENSP00000234170⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 150)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TP53	P04637²^,³, ENSP00000269305⁴	MINT-45889 MINT-45888 I2D: score=5 STRING: ENSP00000269305
TP73	O15350²^,³, ENSP00000367545⁴	MINT-45891 MINT-45887 I2D: score=4 STRING: ENSP00000367545
PRKRA	O75569²^,³, ENSP00000318176⁴	MINT-8267369 I2D: score=2 STRING: ENSP00000318176
UBE3A	Q05086²^,³, ENSP00000381045⁴	MINT-8276380 I2D: score=2 STRING: ENSP00000381045
GSK3B	P49841²^,³	MINT-8256998 I2D: score=2

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0006366	transcription from RNA polymerase II promoter	TAS	2247079

CEBPZ for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CEBPZ for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CEBPZ
4 Novoseek chemical compound relationships for CEBPZ gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
abscisic acid	60.5	19	15247382 (5), 20037472 (3), 9952441 (1), 10792824 (1)
sterol	18.6	2	9430668 (1), 10671504 (1)
cycloheximide	10.1	1	14500791 (1)
tyrosine	0	1	10545030 (1)

Search CenterWatch for drugs/clinical trials and news about CEBPZ

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CEBPZ gene:

NM_005760.2

Unigene Cluster for CEBPZ:

CCAAT/enhancer binding protein (C/EBP), zeta

Hs.135406 [show with all ESTs]

Unigene Representative Sequence: AK125997

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000234170(uc002rpz.3) ENST00000489306 ENST00000446769

miRNA Products:		OriGene 3'-UTR Clone: CEBPZ Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CEBPZ
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate CEBPZ:
		hsa-miR-206 hsa-miR-613 hsa-miR-1
		SwitchGear 3'UTR luciferase reporter plasmid: CEBPZ 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CEBPZ (see all 7) OriGene shRNA RFP: CEBPZ OriGene siRNA: CEBPZ
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		Sirion Biotech Custom design and validation of potent shRNA sequences against CEBPZ

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEBPZ (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEBPZ OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CEBPZ (NM_005760)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEBPZ
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEBPZ

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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEBPZ
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEBPZ

Additional cDNA sequence:

AK125997.1 AK312322.1 BC034475.2 M37197.1

21 DOTS entries:

DT.100659718 DT.454714 DT.121001602 DT.121001617 DT.101963050 DT.95154390 DT.100753970 DT.121001639

DT.305076 DT.91707089 DT.92033793 DT.95351154 DT.100640447 DT.100750952 DT.100852433 DT.100862091

DT.121088715 DT.424337 DT.92033435 DT.95298431 DT.99974102

24/170 AceView cDNA sequences (see all 170):

AI277976 NM_005760 BG112903 BM451841 CB149339 BG251050 BM972414 BM674912

AW043757 CD677164 BU184301 BC034475 BM982595 AV713322 BI087674 AA927754

T27947 BU507120 BF222686 BG719333 AU129715 AA704979 BV207495 BG941330

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CEBPZ expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTTTTGATC

About this image

CEBPZ expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

6 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Bone

Autopod Long Bone

Bone

Endochondral Facial Bones

Bone

Bone

Bone

Bone

Cartilage

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CEBPZ Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CEBPZ

SOURCE GeneReport for Unigene cluster: Hs.135406

SABiosciences Custom PCR Arrays for CEBPZ

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CEBPZ Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEBPZ

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEBPZ

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for CEBPZ gene from 10/34 species (see all 34) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Cebpz^{1 , 5}	CCAAT/enhancer binding protein zeta^{1, 5}	83.48(n)¹ 82.78(a)¹		17 (49.65 cM)⁵ 12607¹ NM_001024806.2¹ NP_001019977.1¹ 78919006⁵
chicken (Gallus gallus)	Aves	CEBPZ¹	CCAAT/enhancer binding protein (C/EBP), zeta	68.48(n) 66.18(a)		421474 NM_001031060.1 NP_001026231.1
lizard (Anolis carolinensis)	Reptilia	CEBPZ⁶	--	63(a)	1 ↔ 1	1(235240775-235262990)
African clawed frog (Xenopus laevis)	Amphibia	Xl.10705²	Xenopus laevis transcribed sequence with weak similarity more	74.12(n)		CA791549.1
zebrafish (Danio rerio)	Actinopterygii	wufi26d06²	wufi26d06	74.2(n)		334005 AW154321.1
fruit fly (Drosophila melanogaster)	Insecta	CG7839¹	CG7839	44.3(n) 32.9(a)		39240 NM_140174.4 NP_648431.3
worm (Caenorhabditis elegans)	Secernentea	CELE_F23B12.7¹	Protein F23B12.7	46.73(n) 34.46(a)		179947 NM_074180.4 NP_506581.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	MAK21(YDR060W)⁴ MAK21¹	Constituent of 66S pre-ribosomal particles, required more⁴ Mak21p¹	48.34(n)¹ 35.67(a)¹		4(570649-573726)⁴ 851632^{1, 4} NP_010345.3¹ NP_010345.1⁴
thale cress (Arabidopsis thaliana)	eudicotyledons	EDA25¹	protein embryo sac development arrest 25	49.65(n) 38.03(a)		843576 NM_105903.3 NP_177388.2
rice (Oryza sativa)	Liliopsida	Os09g0116400¹	hypothetical protein	50.23(n) 39.47(a)		4346414 NM_001069123.1 NP_001062588.1

ENSEMBL Gene Tree for CEBPZ (if available)
TreeFam Gene Tree for CEBPZ (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 2 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs182222217^1,2		--	37428374(+)	`CTCATC/GTATTC`	3	--	int¹		0	--	--	--	--
rs185567209^1,2		--	37428392(+)	`AGGAGA/GATTAG`	3	--	int¹		0	--	--	--	--
rs79475241^1,2	F	--	37428420(+)	`GAATTC/TTTCTA`	3	--	int¹		1		NA	120
rs190057968^1,2		--	37428602(+)	`TAGACA/GAAATA`	3	--	int¹		0	--	--	--	--
rs181478766^1,2		--	37428613(+)	`GTGCTC/TATTAC`	3	--	int¹		0	--	--	--	--
rs2540973^1,2	C,F,A,H	--	37428743(-)	`TGGAAA/GCATTG`	3	--	int¹		23		NS EA NA WA CSA	2182
rs75997595^1,2	C	--	37428823(+)	`ATGGAA/CTCAGA`	3	--	nc-transcript-variantut3¹		0	--	--	--	--
rs76377091^1,2	C	--	37428824(+)	`TGGAAA/TCAGAG`	3	--	ut3¹ nc-transcript-variant		0	--	--	--	--
rs113248228^1,2	C	--	37428920(+)	`TTTGTG/TTTTTA`	4	K T	mis¹ int¹		1		CSA	2
rs16353^1,2	F	--	37428927(+)	`TTTAGTTT/-TTTGA`	5	/L /T /KL	fra¹ int¹		4		EU NA EA	342

HapMap Linkage Disequilibrium report for CEBPZ (37428755 - 37458856 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CEBPZ: --

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CEBPZ

DNA2.0 Custom Variant and Variant Library Synthesis for CEBPZ

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CEBPZ for disorders           About GeneDecksing

OMIM gene information: 612828    OMIM disorders: --

17 diseases for CEBPZ:    About MalaCards

normal pressure hydrocephalus myxoid liposarcoma myeloid leukemia chronic myeloid leukemia

acute myeloid leukemia burkitt's lymphoma cystic fibrosis hydrocephalus

liposarcoma hepatitis b scleroderma fibrosis

leukemia twinning hepatitis neuroblastoma

retinitis

1 disease from the University of Copenhagen DISEASES database for CEBPZ:

Normal pressure hydrocephalus

4 Novoseek disease relationships for CEBPZ gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
sclerosis systemic	18.6	1	12881530 (1)
shock	0	2	14500791 (1)
colorectal cancer	0	1	11888892 (1)
tumors	0	1	8874213 (1)

Export disorders for CEBPZ gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CEBPZ gene, integrated from 9 sources (see all 104):
(articles sorted by number of sources associating them with CEBPZ)

Utopia: connect your pdf to the dynamic
world of online information

A cloned human CCAAT-box-binding factor stimulates transcription from the human hsp70 promoter. (PubMed id 2247079)^{1, 2, 3, 9} Lum L.... Wu B. (1990)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{1, 2} Olsen J.V....Mann M. (2006)
Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)^{1, 2} Hillier L.W....Wilson R.K. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Physical interaction of tumour suppressor p53/p73 wit h CCAAT-binding transcription factor 2 (CTF2) and differential regulation of hu man high-mobility group 1 (HMG1) gene expression. (PubMed id 12534345)^{1, 3} Uramoto H....Kohno K. (2003)
Cloning and characterization of mouse CCAAT binding factor. (PubMed id 8604343)^{1, 9} Hoeppner M.A....Wu B. (1996)
The p65 subunit of NF-I_B inhibits COL1A1 gene transcr iption in human dermal and scleroderma fibroblasts through its recruitment on p romoter by protein interaction with transcriptional activators (c-Krox, Sp1, an d Sp3). (PubMed id 22139845)¹ Beauchef G....Galera P. (2012)
Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)¹ Tsai Y.C....Cristea I.M. (2012)
Aberrant methylation of CCAAT/enhancer binding protei n zeta promoter in acute myeloid leukemia. (PubMed id 21106240)¹ Yao D.M....Yang J. (2011)
A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)

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		AND	OR
Aliases
Disorders
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 10153	HGNC: 24218	AceView: CEBPZ	Ensembl:ENSG00000115816	euGenes: HUgn10153
ECgene: CEBPZ	H-InvDB: CEBPZ

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CEBPZ	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CEBPZ gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for CEBPZ gene:
Search GeneIP for patents involving CEBPZ

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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CEBPZ Gene

CCAAT/enhancer binding protein (C/EBP), zeta

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CEBPZ Gene

CCAAT/enhancer binding protein (C/EBP), zeta

Aliasesfor CEBPZ gene

Summariesfor CEBPZ gene

Genomic Viewsfor CEBPZ gene

Proteinsfor CEBPZ gene

Protein Domains /Familiesfor CEBPZ gene

Functionfor CEBPZ gene

Pathways & Interactionsfor CEBPZ gene

Drugs & Compoundsfor CEBPZ gene

Transcriptsfor CEBPZ gene

Expression for CEBPZ gene

Orthologsfor CEBPZ gene

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Genomic Variantsfor CEBPZ gene

Disorders / Diseasesfor CEBPZ gene

Publicationsfor CEBPZ gene

External Searches for CEBPZ gene

Genome Databases showing CEBPZ gene

Other Databases showing CEBPZ gene

Specialized Databases showing CEBPZ gene

Intellectual Propertyfor CEBPZ gene

Productsfor CEBPZ gene

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Aliases
for CEBPZ gene

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for CEBPZ gene

Genomic Views
for CEBPZ gene

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for CEBPZ gene

Protein Domains /
Families
for CEBPZ gene

Function
for CEBPZ gene

Pathways & Interactions
for CEBPZ gene

Drugs & Compounds
for CEBPZ gene

Transcripts
for CEBPZ gene

Expression
for CEBPZ gene

Orthologs
for CEBPZ gene

Paralogs
for CEBPZ gene

Genomic Variants
for CEBPZ gene

Disorders / Diseases
for CEBPZ gene

Publications
for CEBPZ gene

Intellectual Property
for CEBPZ gene

Products
for CEBPZ gene