Aliases for CEBPD Gene
External Ids for CEBPD Gene
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11. [provided by RefSeq, Sep 2010]
GeneCards Summary for CEBPD Gene
CEBPD (CCAAT/Enhancer Binding Protein (C/EBP), Delta) is a Protein Coding gene. Diseases associated with CEBPD include prostate cancer. Among its related pathways are L1CAM interactions and IL6-mediated signaling events. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is CEBPE.
UniProtKB/Swiss-Prot for CEBPD Gene
C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages