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CEACAM6 Gene

protein-coding   GIFtS: 61
GCID: GC19P042260

Carcinoembryonic Antigen-Related Cell Adhesion Molecule...


(Previous symbol: NCA)
  See CEACAM6-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 6 (Non-Specific
Cross Reacting Antigen)1 2
     CD66c2
NCA1 2 3 5     CEAL2
Non-Specific Crossreacting Antigen2 3     Carcinoembryonic Antigen-Related Cell Adhesion Molecule 62
Normal Cross-Reacting Antigen2 3     CD66c Antigen3

External Ids:    HGNC: 18181   Entrez Gene: 46802   Ensembl: ENSG000000865487   OMIM: 1639805   UniProtKB: P401993   

Export aliases for CEACAM6 gene to outside databases

Previous GC identifers: GC19P042899 GC19P042652 GC19P046935 GC19P046952 GC19P046953 GC19P046954 GC19P038692


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CEACAM6 Gene:
Carcinoembryonic antigen (CEA; MIM 114890) is one of the most widely used tumor markers in serum immunoassay
determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part
from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD
form of CEA (Barnett et al., 1988 (PubMed 3220478)). For background information on the CEA family of genes, see
CEACAM1 (MIM 109770).(supplied by OMIM, Mar 2008)

GeneCards Summary for CEACAM6 Gene:
CEACAM6 (carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)) is a protein-coding gene. Diseases associated with CEACAM6 include cholangiocarcinoma. An important paralog of this gene is PSG9.

Gene Wiki entry for CEACAM6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011109.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the CEACAM6 gene promoter:
         PPAR-gamma1   p53   AML1a   deltaCREB   STAT3   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCEACAM6 promoter sequence
   Search Chromatin IP Primers for CEACAM6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEACAM6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.1-q13.2

CEACAM6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEACAM6 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P042260:  view genomic region     (about GC identifiers)

Start:
42,254,885 bp from pter      End:
42,276,113 bp from pter
Size:
21,229 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CEAM6_HUMAN, P40199 (See protein sequence)
Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 6 precursor  
Size: 344 amino acids; 37195 Da
Secondary accessions: Q13774 Q14920 Q53XP7

Explore the universe of human proteins at neXtProt for CEACAM6: NX_P40199

Explore proteomics data for CEACAM6 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn104, Asn111, Asn115, Asn152, Asn173, Asn197, Asn224, Asn256, Asn274, Asn288,
                                 Asn292, Asn309
  • Modification sites at PhosphoSitePlus

  • See CEACAM6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002474.3  
    ENSEMBL proteins: 
     ENSP00000469752   ENSP00000199764  

    CEACAM6 Human Recombinant Protein Products:

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    Sino Biological Recombinant Protein for CEACAM6
    Sino Biological Cell Lysate for CEACAM6
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CEACAM6

     
    Search eBioscience for Proteins for CEACAM6 

    CEACAM6 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    IGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing
    VSET: Immunoglobulin superfamily / V-set domain containing

    5 InterPro protein domains:
     IPR003598 Ig_sub2
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry P40199

    ProtoNet protein and cluster: P40199

    2 Blocks protein domains:
    IPB003598 Immunoglobulin C-2 type
    IPB013106 Immunoglobulin V-set


    UniProtKB/Swiss-Prot: CEAM6_HUMAN, P40199
    Similarity: Belongs to the immunoglobulin superfamily. CEA family
    Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    Find genes that share domains with CEACAM6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:
         Genatlas biochemistry entry for CEACAM6:
    carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) see CEA@

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with CEACAM6           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CEACAM6:
     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CEACAM6
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CEACAM6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CEACAM6
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CEACAM6

    miRNA
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    miRTarBase miRNAs that target CEACAM6:
    hsa-mir-423-5p (MIRT038060)

    Block miRNA regulation of human, mouse, rat CEACAM6 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CEACAM6
    SwitchGear 3'UTR luciferase reporter plasmidCEACAM6 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CEACAM6

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    Sino Biological Human cDNA Clone for CEACAM6
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM6

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    eBioscience FlowRNA Probe Sets ( VA1-12608) for CEACAM6 


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CEAM6_HUMAN, P40199: Cell membrane; Lipid-anchor, GPI-anchor
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytoskeleton1
    cytosol1
    extracellular1
    mitochondrion1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral component of plasma membrane TAS3220478
    GO:0031225anchored component of membrane IEA--

    Find genes that share ontologies with CEACAM6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including CEACAM6: 
              Lung Cancer in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for CEACAM6

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5 Interacting proteins for CEACAM6 (P401991, 3 ENSP000001997644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CEACAM1P136881, 3, ENSP000001615594EBI-4314501,EBI-4314481 I2D: score=1 STRING: ENSP00000161559
    CEACAM8P319973, ENSP000002443364I2D: score=1 STRING: ENSP00000244336
    CARTPTQ165681, ENSP000002967774EBI-4314501,EBI-4314526 STRING: ENSP00000296777
    CEACAM5ENSP000002219924STRING: ENSP00000221992
    CEACAM7ENSP000000067244STRING: ENSP00000006724
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS3220478
    GO:0007267cell-cell signaling TAS3220478

    Find genes that share ontologies with CEACAM6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CEACAM6 (CEAM6)

    4 Novoseek inferred chemical compound relationships for CEACAM6 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gemcitabine 11.2 8 15173012 (3), 16868542 (2)
    phosphatidylinositol 7.82 5 1913687 (1), 1962149 (1)
    calcium 0 1 8890209 (1)
    paraffin 0 3 2187320 (3)



    Find genes that share compounds with CEACAM6           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CEACAM6 gene: 
    NM_002483.5  

    Unigene Cluster for CEACAM6:

    Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
    Hs.466814  [show with all ESTs]
    Unigene Representative Sequence: NM_002483
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000595740 ENST00000199764(uc002orm.2)
    miRNA
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    Inhib. RNA
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    Flow Cytometry
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    Additional mRNA sequence: 

    AK312542.1 BC005008.1 BT009774.1 M18216.1 M18728.1 M29541.1 

    13 DOTS entries:

    DT.75132501  DT.95283649  DT.97775351  DT.121426879  DT.100817400  DT.92439255  DT.100035515  DT.92439263 
    DT.95091257  DT.95093356  DT.91781710  DT.91785493  DT.95286776 

    Selected AceView cDNA sequences (see all 382):

    AW198029 BM023300 BE696290 AW849400 AW849662 AI696946 CK904504 AW338946 
    AI473526 BE563373 BF197922 AA040122 BU684189 BE049599 AI677998 AI913862 
    AW849353 AW440967 AW075785 AW592911 AW338519 AA366104 BM836489 AI587485 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CEACAM6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGATAAAA
    CEACAM6 Expression
    About this image


    CEACAM6 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Lung (Respiratory System)
             Alveolar type II cells
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Colon (Gastrointestinal Tract)
     
     Esophagus (Gastrointestinal Tract)
    CEACAM6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CEACAM6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.466814
        Pathway & Disease-focused RT2 Profiler PCR Array including CEACAM6: 
              Lung Cancer in human mouse rat

    Primer
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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      --

    ENSEMBL Gene Tree for CEACAM6 (if available)
    TreeFam Gene Tree for CEACAM6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CEACAM6 gene
    PSG92  PSG82  CEACAM42  CEACAM52  PSG112  PSG32  CEACAM72  CEACAM212  
    PSG12  PSG52  PSG62  ENSG000002678812  CEACAM82  CEACAM12  CEACAM182  PSG22  
    CEACAM162  PSG42  CEACAM32  PSG72  
    Selected SIMAP similar genes for CEACAM6 using alignment to 2 protein entries:     CEAM6_HUMAN (see all proteins) (see all similar genes):
    CEA    CEACAM3    CEACAM1    CEACAM5    CEACAM8    CEACAM7
    CEACAM4    PSG2    CEACAM21    PSG    PSG11    PSG1
    PSGII    PSG8    PSG5    SP1    PSG4    PSG9

    Find genes that share paralogs with CEACAM6           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for CEACAM6
    PGOHUM00000234354


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CEACAM6 (see all 447)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1116702791,2
    F--42257403(+) TAATAA/GCCCCT 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1136260471,2
    C,F--42257452(+) ATTTTA/CTATCC 1 -- us2k13Minor allele frequency- C:0.10WA CSA 122
    rs114040761,2
    C--42257458(+) TTTTTT/-GAGAT 1 -- us2k11Minor allele frequency- -:0.50NA 2
    rs1908649111,2
    --42257477(+) TTGAGA/GTGGAG 1 -- us2k10--------
    rs48021301,2
    C,F,H--42257587(+) AGTAGA/CTGGAA 1 -- us2k111Minor allele frequency- C:0.42NA WA CSA EA 373
    rs1829584821,2
    --42257655(+) TTTGCC/TGTGTT 1 -- us2k10--------
    rs97490101,2
    C,F--42257683(+) actccG/Cgacct 1 -- us2k1 tfbs31Minor allele frequency- C:0.50WA 2
    rs1434926261,2
    --42257728(+) CAAAGC/TGTAAA 1 -- us2k10--------
    rs1479902461,2
    C--42258063(+) GGGAAA/CTAACA 1 -- us2k10--------
    rs2004034171,2
    --42258124(+) GCACA-/GAAAAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CEACAM6 (42254885 - 42276113 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CEACAM6:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718580CNV Deletion23290073
    nsv2495CNV Insertion18451855
    nsv911774CNV Loss21882294
    nsv522854CNV Gain19592680
    nsv911775CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    1 Copy Number PCR Panel containing CEACAM6:
    Gastric Cancer
    SeqTarget long-range PCR primers for resequencing CEACAM6
    DNA2.0 Custom Variant and Variant Library Synthesis for CEACAM6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 163980    OMIM disorders: --

    1 disease for CEACAM6:    
    About MalaCards
    cholangiocarcinoma

    2 diseases from the University of Copenhagen DISEASES database for CEACAM6:
    Carcinoma     Colorectal cancer

    Find genes that share disorders with CEACAM6           About GenesLikeMe

    Selected Novoseek inferred disease relationships for CEACAM6 gene (see all 28)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colon carcinoma 65.2 9 2067130 (2), 1815506 (1), 9028835 (1), 11896570 (1) (see all 7)
    gastrointestinal carcinoma 60.2 1 8188529 (1)
    colorectal carcinoma 54.6 6 9041239 (1), 9654079 (1), 9250164 (1), 18159236 (1) (see all 5)
    adenocarcinoma 48.5 24 15729073 (5), 15208677 (4), 14724575 (3), 15316565 (3) (see all 9)
    carcinoma 39.4 16 2125040 (4), 9533775 (3), 2067130 (2), 9250164 (1) (see all 6)
    colon cancer 38 5 9085168 (2), 9028835 (1), 16204051 (1)
    colorectal tumors 37.5 2 10666389 (1), 14512395 (1)
    pancreatic cancer 37.4 5 19055478 (1), 15208677 (1), 19411761 (1), 15729073 (1)
    cholangiocarcinoma 36.3 8 16868542 (5), 19055478 (1), 2187320 (1)
    gastric carcinoma 36 1 8504201 (1)

    Genetic Association Database (GAD): CEACAM6
    Human Genome Epidemiology (HuGE) Navigator: CEACAM6 (3 documents)

    Export disorders for CEACAM6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CEACAM6 gene, integrated from 10 sources (see all 169):
    (articles sorted by number of sources associating them with CEACAM6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Haplotypic diversity in human CEACAM genes: effects on susceptibility to meningococcal disease. (PubMed id 17960155)1, 4 Callaghan M.J....Pollard A.J. (Genes Immun. 2008)
    2. Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)1, 2 Ramachandran P....Loo J.A. (J. Proteome Res. 2006)
    3. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)1, 2 Zhang Z. and Henzel W.J. (Protein Sci. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains. (PubMed id 3220478)1, 2 Barnett T.... Elting J.J. (Genomics 1988)
    6. Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen. (PubMed id 2830274)1, 2 Neumaier M....Shively J.E. (J. Biol. Chem. 1988)
    7. Primary structure of nonspecific crossreacting antigen (NCA), a member of carcinoembryonic antigen (CEA) gene family, deduced from cDNA sequence. (PubMed id 3337731)1, 2 Tawaragi Y.... Nakazato H. (Biochem. Biophys. Res. Commun. 1988)
    8. Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers. (PubMed id 17201906)1, 9 Blumenthal R.D....Goldenberg D.M. (BMC Cancer 2007)
    9. CEACAM6 is a determinant of pancreatic adenocarcinoma cellular invasiveness. (PubMed id 15316565)1, 9 Duxbury M.S....Whang E.E. (Br. J. Cancer 2004)
    10. Carcinoembryonic cell adhesion molecule 6 in human lung: regulated expression of a multifunctional type II cell protein. (PubMed id 19329538)1, 9 Kolla V....Ballard P.L. (Am. J. Physiol. Lung Cell Mol. Physiol. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Disorders
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4680 HGNC: 1818 AceView: CEACAM6 Ensembl:ENSG00000086548 euGenes: HUgn4680
    ECgene: CEACAM6 H-InvDB: CEACAM6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CEACAM6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CEACAM6 gene:
    Search GeneIP for patents involving CEACAM6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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