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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CEACAM5 Gene

protein-coding GIFtS: 62
GCID: GC19P042212

carcinoembryonic antigen-related cell adhesion molecule...

(Previous symbol: CEA)

Explore 111 diseases affiliated with
CEACAM5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5¹ ²
CEA¹ ² ³ ⁵
CD66e¹ ²
Meconium Antigen 100² ³
Carcinoembryonic Antigen³
CD66e Antigen³

External Ids:	HGNC: 1817¹	Entrez Gene: 1048²	Ensembl: ENSG00000105388⁷	OMIM: 114890⁵	UniProtKB: P06731³

Export aliases for CEACAM5 gene to outside databases

Previous GC identifers: GC19P042852 GC19P042604 GC19P046888 GC19P046904 GC19P038644

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CEACAM5:

Members of the CEACAM subfamily, including CEACAM5, belong to the CEA gene family. For general information on the CEA

gene family, see CEACAM1 (MIM 109770).(supplied by OMIM, Oct 2009)

UniProtKB/Swiss-Prot: CEAM5_HUMAN, P06731

Function: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for

E.coli Dr adhesins

Gene Wiki entry for CEACAM5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CEACAM5 gene promoter:
c-Fos AP-1 NRSF form 1 NF-kappaB1 NF-kappaB NRSF form 2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CEACAM5 promoter sequence

Search SABiosciences Chromatin IP Primers for CEACAM5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEACAM5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.1-q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.1-q13.2

CEACAM5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEACAM5 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P042212: view genomic region (about GC identifiers)

Start:	42,212,504 bp from pter	End:	42,234,437 bp from pter
Size:	21,934 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CEAM5_HUMAN, P06731 (See protein sequence)

Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 5 precursor

Size: 702 amino acids; 76795 Da

Subunit: Homodimer. Binding of E.coli Dr adhesins leads to dissociation of the homodimer

Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor

Sequence caution: Sequence=AAA62835.1; Type=Frameshift; Positions=359, 361;

4 PDB 3D structures from and Proteopedia for CEACAM5:

1E07 (3D)

2QSQ (3D)

2QST (3D)

2VER (3D)

Explore the universe of human proteins at neXtProt for CEACAM5: NX_P06731

Post-translational modifications:

Complex immunoreactive glycoprotein with a MW of 180 kDa comprising 60% carbohydrate¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P06731

CEACAM5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_004354.2

ENSEMBL proteins:

ENSP00000221992 ENSP00000385072 ENSP00000381600

Human Recombinant Protein Products for CEACAM5:

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	Novus Biologicals CEACAM5 Protein Novus Biologicals CEACAM5 Lysate
	Sino Biological Recombinant Protein for CEACAM5
	ProSpec Recombinant Protein for CEACAM5
	Uscn Proteins for CEACAM5

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	TAS	3814146
GO:0016323	basolateral plasma membrane	IDA	15052268
GO:0031225	anchored to membrane	IEA	--

CEACAM5 for ontologies About GeneDecksing

CEACAM5 Antibody Products:

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CEACAM5 for domains About GeneDecksing

5/6 InterPro domains/families (see all 6):

IPR003598 Ig_sub2

IPR013098 Ig_I-set

IPR013783 Ig-like_fold

IPR013106 Ig_V-set

IPR007110 Ig-like_dom

Graphical View of Domain Structure for InterPro Entry P06731

ProtoNet protein and cluster: P06731

2 Blocks protein families:

IPB003598 Immunoglobulin C-2 type

IPB013106 Immunoglobulin V-set

UniProtKB/Swiss-Prot: CEAM5_HUMAN, P06731

Similarity: Belongs to the immunoglobulin superfamily. CEA family

Similarity: Contains 7 Ig-like (immunoglobulin-like) domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: CEAM5_HUMAN, P06731

Function: Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for

E.coli Dr adhesins

Genatlas biochemistry entry for CEACAM5:

carcinoembryonic antigen-related cell adhesion molecule 5

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0042802	identical protein binding	IPI	18086185

CEACAM5 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CEACAM5

miRNA Products:		OriGene 3'-UTR Clone: CEACAM5 Browse MicroRNA Expression Plasmids
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CEACAM5 OriGene shRNA RFP: CEACAM5 OriGene siRNA: CEACAM5
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		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM5 OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM5 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CEACAM5 (NM_004363)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM5

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Cell adhesion_Cell-matrix glycoconjugates

Cell adhesion_Cell-matrix glycoconjugates

1.00

Cell adhesion Cell-matrix glycoconjugates

0.97

Adhesion

Adhesion

1.00

Lymphocyte Signaling

Lymphocyte Signaling

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for CEACAM5

Cell adhesion Cell-matrix glycoconjugates

2 Cell Signaling Technology (CST) Pathways for CEACAM5

	Lymphocyte Signaling
	Adhesion

1 GeneGo (Thomson Reuters) Pathway for CEACAM5

Cell adhesion Cell-matrix glycoconjugates

CEACAM5 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for CEACAM5

STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

5/11 Interacting proteins for CEACAM5 (P06731^{1, 2, 3} ENSP00000221992⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 11)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PTCHD2	Q9P2K9³, ENSP00000294484⁴	I2D: score=1 STRING: ENSP00000294484
HNRNPM	P52272³, ENSP00000325376⁴	I2D: score=1 STRING: ENSP00000325376
EWSR1	Q01844³, ENSP00000381031⁴	I2D: score=2 STRING: ENSP00000381031
CEACAM5	P06731¹	EBI-3914938,EBI-3914938
SELE	ENSP00000331736⁴	STRING: ENSP00000331736

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CEACAM5 for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CEACAM5

1 DrugBank Compound for CEACAM5 About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
2,2,5,5-TETRAMETHYL-3-(SULFANYLMETHYL)-2,5-DIHYDRO-1H-PYRROL-1-OL	--	--	target	--	10592235

10/58 Novoseek chemical compound relationships for CEACAM5 gene (see all 58) About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
labetuzumab	79.2	3	15592930 (2), 15809485 (1)
b 723	65.2	21	8941003 (4), 10431845 (4), 7868083 (3), 1689123 (2) (see all 9)
slex	49.3	19	17697728 (4), 11125284 (2), 11291879 (2), 12017332 (2) (see all 6)
mucicarmine	47.9	1	10199475 (1)
5fluorouracil	47.3	10	11943891 (1), 9538153 (1), 2314825 (1), 11448920 (1) (see all 7)
leucovorin	44.2	3	18577244 (1), 15360055 (1), 12420861 (1)
polynucleotide	39.5	9	7712333 (4), 9053029 (1), 7621253 (1), 8118800 (1)
crcs	35.3	3	1962152 (2), 15221959 (1)
irinotecan	33.2	4	20121626 (2), 16601395 (1)
paraffin	29.3	11	12763211 (2), 2187320 (2), 1965432 (1), 11894632 (1) (see all 7)

Search CenterWatch for drugs/clinical trials and news about CEACAM5 / CEAM5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CEACAM5 gene:

NM_004363.2

Unigene Cluster for CEACAM5:

Carcinoembryonic antigen-related cell adhesion molecule 5

Hs.709196 [show with all ESTs]

Unigene Representative Sequence: NM_004363

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000221992(uc010ehz.1 uc002orj.1 uc002orl.3) ENST00000460121

ENST00000405816 ENST00000398599

miRNA Products:		OriGene 3'-UTR Clone: CEACAM5 Browse OriGene MicroRNA Expression Plasmids
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: CEACAM5 (NM_004363)
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Additional cDNA sequence:

AK223101.1 AK310844.1 BC034671.1 CR749337.1 M15042.1 M16234.1 M17191.1 M29540.1

X16455.1

24/27 DOTS entries (see all 27):

DT.100822611 DT.420280 DT.121426886 DT.95290266 DT.92439265 DT.86845447 DT.95214825 DT.95301065

DT.121426861 DT.95289952 DT.121426853 DT.95311400 DT.121426870 DT.121426903 DT.91682705 DT.95286776

DT.98131717 DT.98131718 DT.100035515 DT.40117512 DT.87017412 DT.87017415 DT.120658830 DT.121426872

24/574 AceView cDNA sequences (see all 574):

BG983297 BM836657 BM770005 AA132368 BM836430 AL702861 AL602851 AW008952

AI634287 AI940526 M16234 BF760001 AW819835 BM839383 AW375981 BM836866

BI012906 BM836104 BQ319765 AW071196 BM751729 AW936877 AI582940 X16455

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CEACAM5 (see all 9) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7a	·	7b	·	7c	^	8	^	9a	·	9b	^	10a	·	10b	^	11a	·	11b	^	12a	·	12b	·	12c	·	12d
SP1:
SP2:							-		-		-		-		-		-		-		-		-		-		-		-		-		-		-
SP3:
SP4:
SP5:																																							-

ECgene alternative splicing isoforms for CEACAM5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CEACAM5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image
See CEACAM5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CEACAM5

SOURCE GeneReport for Unigene cluster: Hs.709196

UniProtKB/Swiss-Prot: CEAM5_HUMAN, P06731

Tissue specificity: Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon

SABiosciences Expression via Pathway-Focused PCR Array including CEACAM5:

Lung Cancer in human mouse rat

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CEACAM5 gene from 2/6 species (see all 6) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
lizard (Anolis carolinensis)	Reptilia	--	--	24(a)	possible ortholog	GL344292.1(1263-21096)
zebrafish (Danio rerio)	Actinopterygii	ceacam1¹	carcinoembryonic antigen-related cell adhesion molecule more	42.78(n) 30.17(a)		114465 NM_001113794.1 NP_001107266.1

ENSEMBL Gene Tree for CEACAM5 (if available)
TreeFam Gene Tree for CEACAM5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CEACAM5 gene

PSG9² PSG8² CEACAM4² PSG11² CEACAM7² PSG3² CEACAM21² PSG1²

PSG5² PSG6² CEACAM1² CEACAM8² PSG2² CEACAM6² CEACAM18² CEACAM16²

PSG4² CEACAM3²

18/24 SIMAP similar genes for CEACAM5 using alignment to 5 protein entries: CEAM5_HUMAN (see all proteins) (see all similar genes):

CEA CEACAM6 CEACAM3 CEACAM8 CEACAM1 CEACAM7

PSGII DHFRP2 PSG2 PSG11 PSG5 CEACAM4

PSG PSG1 CEACAM21 PSG8 PSG6 PSG9

CEACAM5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs113834680^1,2		--	42210621(+)	`GGGCTC/TACCGA`	1	--	us2k¹		1		CSA	2
rs10419607^1,2	C,F,H	--	42210659(+)	`ACATGT/GGCATG`	1	--	us2k¹		5		NS EA WA	536
rs74516452^1,2	F	--	42210733(+)	`CCCCAC/TTTCCC`	1	--	us2k¹		1		WA	118
rs111502163^1,2		--	42210785(+)	`GCCTCC/TCCAGG`	1	--	us2k¹		2		CSA WA	120
rs188665034^1,2		--	42210802(+)	`TGACCA/TCCCTC`	1	--	us2k¹		0	--	--	--	--
rs3810152^1,2	C,F,H	--	42210812(+)	`CAGCCG/AGGCCC`	1	--	us2k¹		5		NS EA	532
rs7258524^1,2	C,F,H	--	42210824(+)	`CAGCCC/TAGCAG`	1	--	us2k¹		10		NS EA NA WA	538
rs882152^1,2	F,H	--	42210852(-)	`GCCGAG/AGTGAC`	1	--	us2k¹		5		NS EA WA	534
rs149356638^1,2		--	42211045(+)	`GGGCAA/GCTCCC`	1	--	us2k¹		0	--	--	--	--
rs73932028^1,2	C,F	--	42211068(+)	`GACAGC/TTCAGT`	1	--	us2k¹		5		WA CSA	124

HapMap Linkage Disequilibrium report for CEACAM5 (42212504 - 42234437 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CEACAM5: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CEACAM5

DNA2.0 Custom Variant and Variant Library Synthesis for CEACAM5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CEACAM5 for disorders           About GeneDecksing

OMIM gene information: 114890    OMIM disorders: --

20/111 diseases for CEACAM5 (see all 111):    About MalaCards

linitis plastica pseudomyxoma peritonei extragonadal germ cell tumor fibrous histiocytoma

non-small cell lung carcinoma urethral diverticulum malignant fibrous histiocytoma malignant mesothelioma

serous cystadenoma carcinoma malignant pleural mesothelioma cervical squamous cell carcinoma

actinic keratosis squamous cell carcinoma urachal adenocarcinoma germ cell tumor

secretory meningioma arc syndrome otitis media cystadenoma

1 disease from the University of Copenhagen DISEASES database for CEACAM5:

Colorectal cancer

10/96 Novoseek disease relationships for CEACAM5 gene (see all 96) About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
colorectal cancer	83.2	287	1293545 (7), 11898807 (5), 11289125 (5), 20216474 (4) (see all 99)
colorectal carcinoma	80.9	105	8439497 (4), 12854170 (4), 11948229 (4), 10211983 (3) (see all 56)
metastasis	80.3	433	11948229 (5), 14592671 (5), 10770562 (4), 16719189 (4) (see all 99)
adenocarcinoma	77.3	152	15082298 (5), 2328062 (4), 15337038 (4), 12521132 (3) (see all 93)
tumors	75.8	729	14981971 (6), 1290028 (6), 7914825 (5), 10858386 (5) (see all 99)
gastric cancer	72.2	138	19688060 (5), 8908563 (5), 8908719 (4), 9660027 (4) (see all 68)
nsclc	70.8	138	10808698 (5), 15363304 (5), 16809939 (4), 18646695 (4) (see all 59)
colon carcinoma	67.8	33	1477074 (2), 7688074 (2), 18375392 (2), 15510175 (2) (see all 21)
colon cancer	65.8	58	11964079 (4), 8141873 (3), 2314825 (3), 12636102 (3) (see all 30)
cancer	65.6	216	15017899 (9), 10601548 (4), 16223370 (3), 9704713 (3) (see all 99)

Export disorders for CEACAM5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CEACAM5 gene, integrated from 9 sources (see all 1035):
(articles sorted by number of sources associating them with CEACAM5)

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Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation. (PubMed id 18086185)^{1, 2} Korotkova N.... Matthews S. (2008)
Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)^{1, 2} Ramachandran P....Loo J.A. (2006)
Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23. (PubMed id 10854848)^{1, 2} Boehm M.K. and Perkins S.J. (2000)
Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression. (PubMed id 2342461)^{1, 2} Schrewe H.... Zimmermann W. (1990)
Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains. (PubMed id 3220478)^{1, 2} Barnett T.... Elting J.J. (1988)
Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen. (PubMed id 3670312)^{1, 2} Beauchemin N.... Stanners C.P. (1987)
Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence. (PubMed id 3814146)^{1, 2} Oikawa S.... Kosaki G. (1987)
Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure. (PubMed id 3033671)^{1, 2} Zimmermann W.... von Kleist S. (1987)
Lead time of carcinoembryonic antigen elevation in th e postoperative follow-up of colorectal cancer did not affect the survival rate after recurrence. (PubMed id 20162425)^{1, 9} Chen C.H....Wang J.Y. (2010)
Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth. (PubMed id 11964079)^{1, 9} Wirth T....Juhl H. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 1048	HGNC: 1817	AceView: CEACAM5	Ensembl:ENSG00000105388	euGenes: HUgn1048
ECgene: CEACAM5	H-InvDB: CEACAM5

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for CEACAM5	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CEACAM5	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for CEACAM5 gene
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Patent Information for CEACAM5 gene:
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carcinoembryonic antigen-related cell adhesion molecule...

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CEACAM5 Gene

carcinoembryonic antigen-related cell adhesion molecule...

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