Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CEACAM4 Gene

protein-coding   GIFtS: 49
GCID: GC19M042125

Carcinoembryonic Antigen-Related Cell Adhesion Molecule...


(Previous symbol: CGM7)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 41 2     NCA2
CGM71 2 3     Carcinoembryonic Antigen Gene Family Member 72
Carcinoembryonic Antigen CGM72 3     Nonspecific Cross-Reacting Antigen (NCA)2
Non-Specific Cross-Reacting Antigen W2362 3     Nonspecific Cross-Reacting Antigen W2362
CGM7_HUMAN2     

External Ids:    HGNC: 18161   Entrez Gene: 10892   Ensembl: ENSG000001053527   UniProtKB: O758713   
ORGUL members:         
NONCODE14:n342385      

Export aliases for CEACAM4 gene to outside databases

Previous GC identifers: GC19M042764 GC19M042517 GC19M046801 GC19M046817 GC19M038557


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CEACAM4 Gene: 
CEACAM4 (carcinoembryonic antigen-related cell adhesion molecule 4) is a protein-coding gene, and is affiliated with the lncRNA class. Diseases associated with CEACAM4 include vaginitis, and endometrial carcinoma. An important paralog of this gene is PSG9.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011109.16  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CEACAM4 gene promoter:
         NRSF form 1   HSF1 (long)   CUTL1   LCR-F1   NRSF form 2   POU2F1   POU2F1a   HSF1short   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCEACAM4 promoter sequence
   Search SABiosciences Chromatin IP Primers for CEACAM4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEACAM4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.2

CEACAM4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEACAM4 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M042125:  view genomic region     (about GC identifiers)

Start:
42,125,344 bp from pter      End:
42,133,442 bp from pter
Size:
8,099 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CEAM4_HUMAN, O75871 (See protein sequence)
Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 4 precursor  
Size: 244 amino acids; 25909 Da
Subcellular location: Membrane; Single-pass type I membrane protein
Secondary accessions: Q03715 Q7LDZ7

Explore the universe of human proteins at neXtProt for CEACAM4: NX_O75871

Explore proteomics data for CEACAM4 at MOPED 

Post-translational modifications:

  • UniProtKB: N-glycosylated
  • View neXtProt modification sites for NX_O75871

  • CEACAM4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CEACAM4 Protein Expression
    REFSEQ proteins: NP_001808.2  
    ENSEMBL proteins: 
     ENSP00000221954   ENSP00000473018  

    Human Recombinant Protein Products for CEACAM4: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CEACAM4
    OriGene Protein Over-expression Lysate for CEACAM4
    OriGene MassSpec for CEACAM4 
    OriGene Custom Protein Services for CEACAM4
    GenScript Custom Purified and Recombinant Proteins Services for CEACAM4
    Novus Biologicals CEACAM4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CEACAM4 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane TAS2050678
    GO:0016020membrane TAS2050678

    CEACAM4 for ontologies           About GeneDecksing



    CEACAM4 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for CEACAM4 (CEACAM-4)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CEACAM4
    GenScript Custom Superior Antibodies Services for CEACAM4
    Novus Biologicals CEACAM4 Antibody
    Abcam antibodies for CEACAM4
    Cloud-Clone Corp. Antibodies for CEACAM4 
    ThermoFisher Antibodies for CEACAM4
    LSBio Antibodies in human, mouse, rat for CEACAM4 

    Assay Products for CEACAM4: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CEACAM4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CEACAM4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CEACAM4 
    Cloud-Clone Corp. CLIAs for CEACAM4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    VSET: Immunoglobulin superfamily / V-set domain containing

    4 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry O75871

    ProtoNet protein and cluster: O75871

    1 Blocks protein domain: IPB013106 Immunoglobulin V-set

    UniProtKB/Swiss-Prot: CEAM4_HUMAN, O75871
    Similarity: Belongs to the immunoglobulin superfamily. CEA family
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    CEACAM4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:
         Genatlas biochemistry entry for CEACAM4:
    carcinoembryonic antigen-related cell adhesion molecule 4 (see CEA@)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    CEACAM4 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CEACAM4:
     Decreased Wnt reporter activit  Increased cell death HMECs cel 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CEACAM4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CEACAM4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CEACAM4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CEACAM4 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CEACAM4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CEACAM4
    SwitchGear 3'UTR luciferase reporter plasmidCEACAM4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CEACAM4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEACAM4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CEACAM4
    Sirion Biotech Customized adenovirus for overexpression of CEACAM4

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for CEACAM4 (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CEACAM4 (NM_001817)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEACAM4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM4
    Sirion Biotech Customized lentivirus for stable overexpression of CEACAM4 
                         Customized lentivirus expression plasmids for stable overexpression of CEACAM4 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CEACAM4
    Search LifeMap BioReagents cell lines for CEACAM4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CEACAM4

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CEACAM4 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CEACAM4 (CEAM4)

    2 Novoseek inferred chemical compound relationships for CEACAM4 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    perchloric acid 41.1 1 8395690 (1)
    formaldehyde 9.46 1 2371832 (1)

    Search CenterWatch for drugs/clinical trials and news about CEACAM4 / CEAM4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CEACAM4 gene: 
    NM_001817.2  

    Unigene Cluster for CEACAM4:

    Carcinoembryonic antigen-related cell adhesion molecule 4
    Hs.12  [show with all ESTs]
    Unigene Representative Sequence: NM_001817
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000221954(uc002orh.1 uc010xwd.1) ENST00000600925 ENST00000472081

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CEACAM4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CEACAM4
    SwitchGear 3'UTR luciferase reporter plasmidCEACAM4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CEACAM4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEACAM4
    Clone
    Products:
         
    OriGene clones in human, mouse for CEACAM4 (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CEACAM4 (NM_001817)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEACAM4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM4
    Sirion Biotech Customized lentivirus for stable overexpression of CEACAM4 
                         Customized lentivirus expression plasmids for stable overexpression of CEACAM4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CEACAM4
    OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM4
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CEACAM4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM4

    Additional mRNA sequence: 

    AK298701.1 D90276.1 

    1 DOTS entry:

    DT.75161402 

    10 AceView cDNA sequences:

    BM727358 BX644557 AI721225 BM681735 BX644579 BV202329 AI242105 NM_001817 
    D90276 BF819374 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CEACAM4    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:        -                                 
    SP2:                                          


    ECgene alternative splicing isoforms for CEACAM4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CEACAM4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CEACAM4 Expression
    About this image


    See CEACAM4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CEACAM4

    SOURCE GeneReport for Unigene cluster: Hs.12

    UniProtKB/Swiss-Prot: CEAM4_HUMAN, O75871
    Tissue specificity: Granulocytes

        SABiosciences Custom PCR Arrays for CEACAM4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CEACAM4
    OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM4
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CEACAM4
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM4
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for CEACAM4 gene from 1/4 species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    rat
    (Rattus norvegicus)
    Mammalia Ceacam101 carcinoembryonic antigen-related cell adhesion molecule more 63.87(n)
    48.09(a)
      287009  NM_173339.1  NP_775461.1 


    ENSEMBL Gene Tree for CEACAM4 (if available)
    TreeFam Gene Tree for CEACAM4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CEACAM4 gene
    PSG92  PSG82  CEACAM52  PSG112  PSG32  CEACAM72  CEACAM212  PSG12  
    PSG52  PSG62  ENSG000002678812  CEACAM82  CEACAM12  CEACAM62  CEACAM182  PSG22  
    CEACAM162  PSG42  PSG72  CEACAM32  
    18/21 SIMAP similar genes for CEACAM4 using alignment to 2 protein entries:     CEAM4_HUMAN (see all proteins) (see all similar genes):
    CEACAM3    CEACAM8    CEA    CEACAM6    CEACAM7    DHFRP2
    SP1    CEACAM1    DKFZp781M2392    PSG    PSG5    PSG1
    PSG3    PSG7    PSG9    PSG4    PSG8    CEACAM5

    CEACAM4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/320 SNPs in CEACAM4 are shown (see all 320)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1473535321,2
    --42124867(+) GAACCC/TAGTGG 1 -- ds50010--------
    rs1834583641,2
    --42124906(+) TTGGGA/GACAGG 1 -- ds50010--------
    rs1484148381,2
    C--42124917(+) TAAGTG/TCATTT 1 -- ds50010--------
    rs1425054621,2
    --42124998(+) GCTGCA/GTAGGG 1 -- ds50010--------
    rs1513349771,2
    --42125062(+) GTGGAC/TATCAG 1 -- ds50010--------
    rs1393977351,2
    C--42125128(+) GCTGGA/GGCTGT 1 -- ds50010--------
    rs1444224811,2
    C--42125164(+) GTGAGG/TACAGC 1 -- ds50010--------
    rs1861688041,2
    --42125175(+) TGAGCA/GCTCGG 1 -- ds50010--------
    rs780745071,2
    C,F--42125250(+) CCAACC/TCCTAT 1 -- ds50011Minor allele frequency- T:0.02NA 120
    rs1897525571,2
    C--42125270(+) CCAGGA/GAAGAG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for CEACAM4 (42125344 - 42133442 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CEACAM4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2260460CNV Deletion18987734
    esv2718577CNV Deletion23290073
    esv2718578CNV Deletion23290073
    nsv2494CNV Insertion18451855
    nsv519408CNV Gain19592680
    nsv522854CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CEACAM4
    DNA2.0 Custom Variant and Variant Library Synthesis for CEACAM4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    19 diseases for CEACAM4:    About MalaCards
    vaginitis    endometrial carcinoma    papillary thyroid carcinoma    papillary carcinoma
    chronic myeloid leukemia    colon cancer    acute lymphoblastic leukemia    myeloid leukemia
    colorectal cancer    adenoma    lymphoblastic leukemia    psoriasis
    thyroiditis    leukemia    cervicitis    melanoma
    endotheliitis    breast cancer    hepatitis


    CEACAM4 for disorders           About GeneDecksing

    10/12 Novoseek inferred disease relationships for CEACAM4 gene (see all 12)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colon carcinoma 62.1 1 9196893 (1)
    colorectal carcinoma 50 5 9041239 (2), 9250164 (1), 1962152 (1), 2125040 (1)
    tumors 32.4 6 10910050 (1), 9196893 (1), 9756415 (1), 19531051 (1) (see all 6)
    adenocarcinoma 30.1 1 7690349 (1)
    adenoma 29 2 2125040 (2)
    myeloid leukemia chronic 24.5 3 2332039 (1), 2011210 (1)
    carcinoma 23.6 2 2341397 (1), 2125040 (1)
    colon cancer 21.8 1 9085168 (1)
    endometrial carcinoma 21 1 7690349 (1)
    colorectal cancer 2.42 1 9085168 (1)


    Export disorders for CEACAM4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CEACAM4 gene, integrated from 9 sources (see all 76):
    (articles sorted by number of sources associating them with CEACAM4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of nonspecific cross-reacting antigens in human granulocytes. (PubMed id 2050678)1, 2, 3, 9 Kuroki M....Matsuoka Y. (1991)
    2. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
    3. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (2000)
    4. Sequence and glycosylation site identity of two distinct glycoforms of nonspecific cross-reacting antigen as demonstrated by sequence analysis and fast atom bombardment mass spectrometry. (PubMed id 2341397)9 Hefta S.A....Shively J.E. (1990)
    5. Nonspecific cross-reacting antigen (NCA) expressed by human granulocytes: six species with different peptide sizes and membrane anchoring forms. (PubMed id 2154215)9 Kuroki M....Matsuoka Y. (1990)
    6. Prognostic significance of secondary cytogenetic changes and nonspecific cross-reacting antigen (NCA) in patients with Ph-positive chronic myeloid leukemia. (PubMed id 2332039)9 Haus O....Kotlarek-Haus S. (1990)
    7. [Nonspecific cross-reacting antigen (NCA)] (PubMed id 16149618)9 Hayashi T. and Imai K. (2005)
    8. A polymerase-chain-reaction assay for the specific identification of transcripts encoded by individual carcinoembryonic antigen (CEA)-gene-family members. (PubMed id 7690349)9 Thompson J....Zimmermann W. (1993)
    9. Identification of three new genes and estimation of the size of the carcinoembryonic antigen family. (PubMed id 1427854)9 Khan W.N....Hammarstroem S. (1992)
    10. Behavior in immunoblotting of dimeric and monomeric f orms of nonspecific cross-reacting antigen (NCA-50) from normal lung. (PubMed id 1919023)9 Krop-Watorek A....Lisowska E. (1991)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1089 HGNC: 1816 AceView: CEACAM4 Ensembl:ENSG00000105352 euGenes: HUgn1089
    ECgene: CEACAM4 H-InvDB: CEACAM4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CEACAM4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CEACAM4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CEACAM4 gene:
    Search GeneIP for patents involving CEACAM4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for CEACAM4 (CEACAM-4)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CEACAM4  
     OriGene qPCR primer pairs and template standards for CEACAM4   OriGene Protein Over-expression Lysate for CEACAM4  
     OriGene MassSpec something-or-other for CEACAM4   OriGene clones in human, mouse for CEACAM4  
     OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM4   OriGene Purified Protein for CEACAM4  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CEACAM4   OriGene Custom Protein Services for CEACAM4  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CEACAM4
     QIAGEN SeqTarget long-range PCR primers for resequencing CEACAM4
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEACAM4
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEACAM4
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM4
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM4
     GenScript Custom Purified and Recombinant Proteins Services for CEACAM4 GenScript cDNA clones with any tag delivered in your preferred vector for CEACAM4
     GenScript Custom Assay Services for CEACAM4 GenScript Custom Superior Antibodies Services for CEACAM4
     GenScript Custom overexpressing Cell Line Services for CEACAM4 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CEACAM4 promoter
     Search Chromatin IP Primers for CEACAM4
     RT2 qPCR Primer Assay in human, mouse / rat CEACAM4
     Search GNC Networks for CEACAM4
     SABiosciences Custom PCR Arrays for CEACAM4
     Search Tocris compounds for CEACAM4 (CEAM4)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CEACAM4 antibodies
     CEACAM4 lysates
     Antibodies for CEACAM4
     See all of Abcam's Antibodies, Kits and Proteins for CEACAM4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for CEACAM4
     Antibodies for CEACAM4
     ELISAs for CEACAM4
     CLIAs for CEACAM4
     Search LifeMap BioReagents cell lines for CEACAM4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM4
     SwitchGear 3'UTR luciferase reporter plasmids for CEACAM4
     SwitchGear Promoter luciferase reporter plasmids for CEACAM4
     ThermoFisher Antibodies for CEACAM4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM4
     inGenious Targeting Laboratory - Custom generated mouse model solutions for CEACAM4
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CEACAM4
    Customized:
     lentivirus for stable overexpression of CEACAM4
     lentivirus expression plasmids for stable overexpression of CEACAM4
     adenovirus for overexpression of CEACAM4
     LSBio Antibodies in human, mouse, rat for CEACAM4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CEACAM4 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4