Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CEACAM4 Gene

protein-coding   GIFtS: 49
GCID: GC19M042125

Carcinoembryonic Antigen-Related Cell Adhesion Molecule...


(Previous symbol: CGM7)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 41 2     NCA2
CGM71 2 3     Carcinoembryonic Antigen Gene Family Member 72
Carcinoembryonic Antigen CGM72 3     Nonspecific Cross-Reacting Antigen (NCA)2
Non-Specific Cross-Reacting Antigen W2362 3     Nonspecific Cross-Reacting Antigen W2362
CGM7_HUMAN2     

External Ids:    HGNC: 18161   Entrez Gene: 10892   Ensembl: ENSG000001053527   UniProtKB: O758713   

Export aliases for CEACAM4 gene to outside databases

Previous GC identifers: GC19M042764 GC19M042517 GC19M046801 GC19M046817 GC19M038557


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for CEACAM4 Gene:
CEACAM4 (carcinoembryonic antigen-related cell adhesion molecule 4) is a protein-coding gene. Diseases associated with CEACAM4 include vaginitis, and endometrial carcinoma. An important paralog of this gene is PSG9.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000019.10  NT_011109.17  NT_187620.1  NC_018930.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CEACAM4 gene promoter:
         NRSF form 1   HSF1 (long)   CUTL1   LCR-F1   NRSF form 2   POU2F1   POU2F1a   HSF1short   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCEACAM4 promoter sequence
   Search Chromatin IP Primers for CEACAM4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEACAM4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2   Ensembl cytogenetic band:  19q13.2   HGNC cytogenetic band: 19q13.2

CEACAM4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CEACAM4 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M042125:  view genomic region     (about GC identifiers)

Start:
42,125,344 bp from pter      End:
42,133,442 bp from pter
Size:
8,099 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CEAM4_HUMAN, O75871 (See protein sequence)
Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 4 precursor  
Size: 244 amino acids; 25909 Da
Secondary accessions: Q03715 Q7LDZ7

Explore the universe of human proteins at neXtProt for CEACAM4: NX_O75871

Post-translational modifications: 

  • N-glycosylated1
  • Glycosylation2 at Asn57, Asn104, Asn111, Asn126
  • REFSEQ proteins: NP_001808.2  
    ENSEMBL proteins: 
     ENSP00000221954   ENSP00000473018  

    CEACAM4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for CEACAM4
    OriGene Protein Over-expression Lysate for CEACAM4
    OriGene MassSpec for CEACAM4
    OriGene Custom Protein Services for CEACAM4
    GenScript Custom Purified and Recombinant Proteins Services for CEACAM4
    Novus Biologicals CEACAM4 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CEACAM4

    CEACAM4 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for CEACAM4 (CEACAM-4)
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CEACAM4
    Novus Biologicals CEACAM4 Antibody
    Abcam antibodies for CEACAM4 (P40199, O75871)
    Cloud-Clone Corp. Antibodies for CEACAM4
    ThermoFisher Antibodies for CEACAM4
    LSBio Antibodies in human, mouse, rat for CEACAM4

    CEACAM4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CEACAM4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CEACAM4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CEACAM4
    Cloud-Clone Corp. CLIAs for CEACAM4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    VSET: Immunoglobulin superfamily / V-set domain containing

    4 InterPro protein domains:
     IPR013783 Ig-like_fold
     IPR013106 Ig_V-set
     IPR007110 Ig-like_dom
     IPR003599 Ig_sub

    Graphical View of Domain Structure for InterPro Entry O75871

    ProtoNet protein and cluster: O75871

    1 Blocks protein domain: IPB013106 Immunoglobulin V-set

    UniProtKB/Swiss-Prot: CEAM4_HUMAN, O75871
    Similarity: Belongs to the immunoglobulin superfamily. CEA family
    Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain


    CEACAM4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:
         Genatlas biochemistry entry for CEACAM4:
    carcinoembryonic antigen-related cell adhesion molecule 4 (see CEA@)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    CEACAM4 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CEACAM4:
     Decreased Wnt reporter activit  Increased cell death HMECs cel 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CEACAM4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CEACAM4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CEACAM4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CEACAM4

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CEACAM4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CEACAM4
    SwitchGear 3'UTR luciferase reporter plasmidCEACAM4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CEACAM4
    Predesigned siRNA for gene silencing in human, mouse, rat CEACAM4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CEACAM4

    Clone
    Products:
         
    OriGene clones in human, mouse for CEACAM4 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CEACAM4 (NM_001817)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEACAM4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CEACAM4
    Browse ESI BIO Cell Lines and PureStem Progenitors for CEACAM4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    CEAM4_HUMAN, O75871: Membrane; Single-pass type I membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    mitochondrion2
    extracellular1
    nucleus1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral component of plasma membrane TAS2050678
    GO:0016020membrane TAS2050678

    CEACAM4 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CEACAM4
    Interactions:

        Search GeneGlobe Interaction Network for CEACAM4

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CEACAM4 (CEAM4)

    2 Novoseek inferred chemical compound relationships for CEACAM4 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    perchloric acid 41.1 1 8395690 (1)
    formaldehyde 9.46 1 2371832 (1)



    CEACAM4 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CEACAM4 gene: 
    NM_001817.3  

    Unigene Cluster for CEACAM4:

    Carcinoembryonic antigen-related cell adhesion molecule 4
    Hs.12  [show with all ESTs]
    Unigene Representative Sequence: NM_001817
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000221954(uc002orh.1 uc010xwd.1) ENST00000600925 ENST00000472081

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CEACAM4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CEACAM4
    SwitchGear 3'UTR luciferase reporter plasmidCEACAM4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CEACAM4
    Predesigned siRNA for gene silencing in human, mouse, rat CEACAM4
    Clone
    Products:
         
    OriGene clones in human, mouse for CEACAM4 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CEACAM4 (NM_001817)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CEACAM4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CEACAM4
    OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM4
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CEACAM4
      QuantiTect SYBR Green Assays in human, mouse, rat CEACAM4
      QuantiFast Probe-based Assays in human, mouse, rat CEACAM4

    Additional mRNA sequence: 

    AK298701.1 D90276.1 

    1 DOTS entry:

    DT.75161402 

    10 AceView cDNA sequences:

    BM727358 AI721225 BM681735 BX644579 BV202329 BX644557 D90276 NM_001817 
    AI242105 BF819374 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for CEACAM4    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:        -                                 
    SP2:                                          


    ECgene alternative splicing isoforms for CEACAM4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CEACAM4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CEACAM4 Expression
    About this image

    CEACAM4 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.12

    UniProtKB/Swiss-Prot: CEAM4_HUMAN, O75871
    Tissue specificity: Granulocytes

        Custom PCR Arrays for CEACAM4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CEACAM4
    OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM4
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CEACAM4
    QuantiTect SYBR Green Assays in human, mouse, rat CEACAM4
    QuantiFast Probe-based Assays in human, mouse, rat CEACAM4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus
      --

    ENSEMBL Gene Tree for CEACAM4 (if available)
    TreeFam Gene Tree for CEACAM4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CEACAM4 gene
    PSG92  PSG82  CEACAM52  PSG112  PSG32  CEACAM72  CEACAM212  PSG12  
    PSG52  PSG62  ENSG000002678812  CEACAM82  CEACAM12  CEACAM62  CEACAM182  PSG22  
    CEACAM162  PSG42  PSG72  CEACAM32  
    Selected SIMAP similar genes for CEACAM4 using alignment to 2 protein entries:     CEAM4_HUMAN (see all proteins) (see all similar genes):
    CEACAM3    CEACAM8    CEA    CEACAM6    CEACAM7    DHFRP2
    SP1    CEACAM1    DKFZp781M2392    PSG    PSG5    PSG9
    CEACAM5    PSG1    PSG3    PSG7    PSG8    PSG4

    CEACAM4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CEACAM4 (see all 320)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1473535321,2
    --42124867(+) GAACCC/TAGTGG 1 -- ds50010--------
    rs1834583641,2
    --42124906(+) TTGGGA/GACAGG 1 -- ds50010--------
    rs1484148381,2
    C--42124917(+) TAAGTG/TCATTT 1 -- ds50010--------
    rs1425054621,2
    --42124998(+) GCTGCA/GTAGGG 1 -- ds50010--------
    rs1513349771,2
    --42125062(+) GTGGAC/TATCAG 1 -- ds50010--------
    rs1393977351,2
    C--42125128(+) GCTGGA/GGCTGT 1 -- ds50010--------
    rs1444224811,2
    C--42125164(+) GTGAGG/TACAGC 1 -- ds50010--------
    rs1861688041,2
    --42125175(+) TGAGCA/GCTCGG 1 -- ds50010--------
    rs780745071,2
    C,F--42125250(+) CCAACC/TCCTAT 1 -- ds50011Minor allele frequency- T:0.02NA 120
    rs1897525571,2
    C--42125270(+) CCAGGA/GAAGAG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for CEACAM4 (42125344 - 42133442 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CEACAM4:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2260460CNV Deletion18987734
    esv2718577CNV Deletion23290073
    esv2718578CNV Deletion23290073
    nsv2494CNV Insertion18451855
    nsv519408CNV Gain19592680
    nsv522854CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CEACAM4
    DNA2.0 Custom Variant and Variant Library Synthesis for CEACAM4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    18 diseases for CEACAM4:    
    About MalaCards
    vaginitis    endometrial carcinoma    papillary thyroid carcinoma    chronic myeloid leukemia
    papillary carcinoma    myeloid leukemia    colorectal cancer    psoriasis
    lymphoblastic leukemia    adenoma    thyroiditis    leukemia
    cervicitis    endotheliitis    melanoma    adenocarcinoma
    hepatitis    breast cancer


    CEACAM4 for disorders           About GeneDecksing

    Selected Novoseek inferred disease relationships for CEACAM4 gene (see all 12)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    colon carcinoma 62.1 1 9196893 (1)
    colorectal carcinoma 50 5 9041239 (2), 9250164 (1), 1962152 (1), 2125040 (1)
    tumors 32.4 6 10910050 (1), 9196893 (1), 9756415 (1), 19531051 (1) (see all 6)
    adenocarcinoma 30.1 1 7690349 (1)
    adenoma 29 2 2125040 (2)
    myeloid leukemia chronic 24.5 3 2332039 (1), 2011210 (1)
    carcinoma 23.6 2 2341397 (1), 2125040 (1)
    colon cancer 21.8 1 9085168 (1)
    endometrial carcinoma 21 1 7690349 (1)
    colorectal cancer 2.42 1 9085168 (1)


    Export disorders for CEACAM4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CEACAM4 gene, integrated from 10 sources (see all 77):
    (articles sorted by number of sources associating them with CEACAM4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of nonspecific cross-reacting antigens in human granulocytes. (PubMed id 2050678)1, 2, 3, 9 Kuroki M....Matsuoka Y. (J. Biol. Chem. 1991)
    2. A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication. (PubMed id 19460752)1 Yeung M.L....Jeang K.T. (J. Biol. Chem. 2009)
    3. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (Nature 2004)
    4. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800)1 Dias Neto E....Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    5. Sequence and glycosylation site identity of two distinct glycoforms of nonspecific cross-reacting antigen as demonstrated by sequence analysis and fast atom bombardment mass spectrometry. (PubMed id 2341397)9 Hefta S.A....Shively J.E. (J. Biol. Chem. 1990)
    6. Nonspecific cross-reacting antigen (NCA) expressed by human granulocytes: six species with different peptide sizes and membrane anchoring forms. (PubMed id 2154215)9 Kuroki M....Matsuoka Y. (Biochem. Biophys. Res. Commun. 1990)
    7. Prognostic significance of secondary cytogenetic changes and nonspecific cross-reacting antigen (NCA) in patients with Ph-positive chronic myeloid leukemia. (PubMed id 2332039)9 Haus O....Kotlarek-Haus S. (Exp. Mol. Pathol. 1990)
    8. [Nonspecific cross-reacting antigen (NCA)]. (PubMed id 16149618)9 Hayashi T. and Imai K. (Nippon Rinsho 2005)
    9. A polymerase-chain-reaction assay for the specific identification of transcripts encoded by individual carcinoembryonic antigen (CEA)-gene-family members. (PubMed id 7690349)9 Thompson J....Zimmermann W. (Int. J. Cancer 1993)
    10. Identification of three new genes and estimation of the size of the carcinoembryonic antigen family. (PubMed id 1427854)9 Khan W.N....Hammarstroem S. (Genomics 1992)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 1089 HGNC: 1816 AceView: CEACAM4 Ensembl:ENSG00000105352 euGenes: HUgn1089
    ECgene: CEACAM4 H-InvDB: CEACAM4

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CEACAM4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CEACAM4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CEACAM4 gene:
    Search GeneIP for patents involving CEACAM4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Antibodies for CEACAM4 (CEACAM-4)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     cDNA Clones for CEACAM4 (CEACAM-4)   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CEACAM4  
     OriGene qPCR primer pairs and template standards for CEACAM4   OriGene Protein Over-expression Lysate for CEACAM4  
     OriGene MassSpec something-or-other for CEACAM4   OriGene clones in human, mouse for CEACAM4  
     OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM4   OriGene Purified Protein for CEACAM4  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CEACAM4   OriGene Custom Protein Services for CEACAM4  

     
     
     Block miRNA regulation of human, mouse, rat CEACAM4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CEACAM4
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEACAM4 Predesigned siRNA for gene silencing in human, mouse, rat CEACAM4
     QuantiFast Probe-based Assays in human, mouse, rat CEACAM4 QuantiTect SYBR Green Assays in human, mouse, rat CEACAM4
     Custom PCR Arrays for CEACAM4 Search Chromatin IP Primers for CEACAM4
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CEACAM4  Search GeneGlobe Interaction Network for CEACAM4
     Regulatory tfbs in CEACAM4 promoter
     GenScript Custom Purified and Recombinant Proteins Services for CEACAM4 GenScript cDNA clones with any tag delivered in your preferred vector for CEACAM4
     GenScript Custom Assay Services for CEACAM4 GenScript Custom overexpressing Cell Line Services for CEACAM4
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CEACAM4 (CEAM4)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CEACAM4 antibodies
     CEACAM4 lysates
     Antibodies for CEACAM4
     See all of Abcam's Antibodies, Kits and Proteins for CEACAM4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CEACAM4
     Antibodies for CEACAM4
     ELISAs for CEACAM4
     CLIAs for CEACAM4



     Browse ESI BIO Cell Lines and PureStem Progenitors for CEACAM4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM4
     SwitchGear 3'UTR luciferase reporter plasmids for CEACAM4
     SwitchGear Promoter luciferase reporter plasmids for CEACAM4
     ThermoFisher Antibodies for CEACAM4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM4
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CEACAM4
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CEACAM4
     LSBio Antibodies in human, mouse, rat for CEACAM4
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CEACAM4 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4