CEACAM20 Gene
protein-coding GIFtS: 36
GCID: GC19M045005
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Carcinoembryonic Antigen-Related Cell Adhesion Molecule...
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Aliases
for CEACAM20 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
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| Aliases |
|---|
| Carcinoembryonic Antigen-Related Cell Adhesion Molecule 201 2 | | GPAD93662 | | UNQ93662 |
Export aliases for CEACAM20 gene to outside databasesPrevious GC identifers: GC19M049698 GC19M041442 |
Summaries
for CEACAM20 gene(According to Entrez Gene,
GeneCards,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
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GeneCards Summary for CEACAM20 Gene:
CEACAM20 (carcinoembryonic antigen-related cell adhesion molecule 20) is a protein-coding gene. Diseases associated with CEACAM20 include prostatitis.
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Genomic Views
for CEACAM20 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 75),
Regulatory elements and Epigenetics data according to
QIAGEN, and/or
SwitchGear Genomics)
About This Section
TryGeneCards Plus | Regulatory elements:
 Regulatory transcription factor binding sites in the CEACAM20 gene promoter:
Bach1 COUP-TF1 ER-alpha COUP Pax-2 HNF-4alpha2 Pax-2a Nkx5-1 HNF-4alpha1 COUP-TF
Other transcription factors
Search Chromatin IP Primers for CEACAM20
Epigenetics:
| | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEACAM20 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.31 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.31CEACAM20 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M045005: view genomic region
(about GC identifiers)
Start:
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45,005,729 bp from pter |
End:
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45,033,811 bp from pter |
Size:
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28,083 bases |
Orientation:
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minus strand |
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Proteins
for CEACAM20 gene
(According to
1UniProtKB,
HORDE,
2neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Antibodies by
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CEA20_HUMAN, Q6UY09 (See
protein sequence)Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 20 precursor Size: 585 amino acids; 64502 DaExplore the universe of human proteins at neXtProt for CEACAM20: NX_Q6UY09
Explore proteomics data for CEACAM20 at MOPED
Post-translational modifications:  Glycosylation2 at Asn96, Asn105, Asn280, Asn306, Asn317, Asn368, Asn415
See CEACAM20 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB
REFSEQ proteins (4 alternative transcripts):
NP_001096067.2 NP_001096068.2 NP_001096069.2 NP_001096070.2
CEACAM20 Human Recombinant
Protein Products:CEACAM20 Antibody
Products:CEACAM20 Assay Products: |
Domains /
Families
for CEACAM20 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
TryGeneCards Plus | HGNC Gene Families:
ISET: Immunoglobulin superfamily / I-set domain containingIGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing
5 InterPro protein domains:Graphical View of Domain Structure for InterPro Entry Q6UY09ProtoNet protein and cluster: Q6UY09 UniProtKB/Swiss-Prot: CEA20_HUMAN, Q6UY09Similarity: Belongs to the immunoglobulin superfamily. CEA familySimilarity: Contains 4 Ig-like C2-type (immunoglobulin-like) domains
CEACAM20 for domains About GeneDecksing
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Function
for CEACAM20 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
transcription factor targeting from QIAGEN
and/or HOMER,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
SwitchGear Genomics,
Gene Editing from DNA2.0,
Clones from OriGene,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
ESI BIO,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Phenotypes:
1 GenomeRNAi human phenotype for CEACAM20:
Animal Models:
Inhib. RNA
Products: |  | OriGene RNAi products in human, mouse, rat for CEACAM20
| | | Predesigned siRNA for gene silencing in human, mouse, rat CEACAM20 |
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for CEACAM20 | |  | Browse ESI BIO Cell Lines and PureStem Progenitors for CEACAM20  | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM20 |
Localization
for CEACAM20 gene
(According to UniProtKB, COMPARTMENTS Subcellular localization database,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot CEA20_HUMAN, Q6UY09: Membrane; Single-pass type I membrane protein (Potential)Subcellular locations from COMPARTMENTS:
| Compartment | Confidence |
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| plasma membrane | 2 | | cytosol | 1 | | endoplasmic reticulum | 1 | | extracellular | 1 | | golgi apparatus | 1 | | lysosome | 1 | | mitochondrion | 1 | | nucleus | 1 |
Gene Ontology (GO): 1 cellular component term: About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral component of membrane |
IEA | -- |
CEACAM20 for ontologies About GeneDecksing
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Pathways & Interactions
for CEACAM20 gene
(SuperPaths according to PathCards,
Pathways according to
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
QIAGEN,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene).
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Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CEACAM20
Interactions:
Search GeneGlobe Interaction Network for CEACAM20
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Drugs & Compounds
for CEACAM20 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience,
ApexBio,
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB)
About This Section
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 Browse compounds at ApexBio
 Browse Tocris compounds for CEACAM20 (CEA20)
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Transcripts
for CEACAM20 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
SwitchGear Genomics,
Tagged/untagged cDNA clones from
OriGene,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene, and/or
QIAGEN
)
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REFSEQ mRNAs for CEACAM20 gene (5 alternative transcripts): NM_198444.1 NM_001102597.2 NM_001102598.2 NM_001102599.2 NM_001102600.2 9 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000454753(processed_transcript) ENST00000421432(processed_transcript) ENST00000448350(processed_transcript) ENST00000431738(processed_transcript) ENST00000414638(processed_transcript)
ENST00000445209(processed_transcript) ENST00000412211(processed_transcript) ENST00000424903(processed_transcript) ENST00000316962(processed_transcript)
Inhib. RNA
Products: | | OriGene RNAi products in human, mouse, rat for CEACAM20
| |
| | Predesigned siRNA for gene silencing in human, mouse, rat CEACAM20 |
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM20
| | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CEACAM20 | | | QuantiTect SYBR Green Assays in human, mouse, rat CEACAM20 | | | QuantiFast Probe-based Assays in human, mouse, rat CEACAM20 |
2 AceView cDNA sequences: AY358129 NM_198444
GeneLoc Exon Structure
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Expression
for CEACAM20 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MaxQB,
plus additional links to
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
QIAGEN,
Primers from
OriGene, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CEACAM20 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image CEACAM20 Protein expression data from MOPED1, PaxDb2 and
MaxQB3: About this image
Custom PCR Arrays for CEACAM20
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM20
| | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CEACAM20 | | | QuantiTect SYBR Green Assays in human, mouse, rat CEACAM20 | | | QuantiFast Probe-based Assays in human, mouse, rat CEACAM20 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM20 |
Orthologs
for CEACAM20 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
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This gene was present in the common ancestor of chordates.
Orthologs for CEACAM20 gene from Selected species (see all 5) About this table
ENSEMBL Gene Tree for CEACAM20 (if available)
TreeFam Gene Tree for CEACAM20 (if available) |
Paralogs
for CEACAM20 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
TryGeneCards Plus | Paralogs for CEACAM20 gene
3 SIMAP similar genes for CEACAM20 using alignment to 5 protein entries: CEA20_HUMAN (see all proteins):CEACAM1 PSGII PSG1
CEACAM20 for paralogs About GeneDecksing
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Genomic Variants
for CEACAM20 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD), the Human Cytochrome P450 Allele
Nomenclature Database, and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for CEACAM20 (45005729 - 45033811 bp)
Structural Variations
Database of Genomic Variants (DGV) 1 variation for CEACAM20: About this table
| | Site Specific Mutation Identification with PCR Assays |
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Disorders
/ Diseases
for CEACAM20 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
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1  disease for CEACAM20:
About MalaCardsprostatitis
CEACAM20 for disorders About GeneDecksing
Genetic Association Database (GAD): CEACAM20
Human Genome Epidemiology (HuGE) Navigator: CEACAM20 (1 document)
Export disorders for CEACAM20 gene to outside databases
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Publications
for CEACAM20 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
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PubMed articles for CEACAM20 gene integrated from 10 sources:
(articles sorted by number of sources associating them with CEACAM20) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (Genome Res. 2003)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
- Role of CEACAM1 and CEACAM20 in an in vitro model of prostate morphogenesis. (PubMed id 23358633)1 Zhang H....Shively J.E. (PLoS ONE 2013)
- Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. (PubMed id 16139472)1 Zebhauser R....Zimmermann W. (Genomics 2005)
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External Searches for CEACAM20 gene (in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing CEACAM20 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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|
Other Databases showing CEACAM20 gene
(According to HUGE)
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Specialized Databases showing CEACAM20 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for CEACAM20 | Pharmacogenomics, SNPs, Pathways |
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TryGeneCards Plus | Patent Information for CEACAM20 gene:
Search GeneIP for patents involving CEACAM20
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for CEACAM20 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or
ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
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|  | Block miRNA regulation of human, mouse, rat CEACAM20 using miScript Target Protectors | | SeqTarget long-range PCR primers for resequencing CEACAM20 | | | DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CEACAM20 | | Predesigned siRNA for gene silencing in human, mouse, rat CEACAM20 | | | QuantiFast Probe-based Assays in human, mouse, rat CEACAM20 | | QuantiTect SYBR Green Assays in human, mouse, rat CEACAM20 | | | Custom PCR Arrays for CEACAM20 | | Search Chromatin IP Primers for CEACAM20 | | | Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CEACAM20 | | Search GeneGlobe Interaction Network for CEACAM20 | | | Regulatory tfbs in CEACAM20 promoter |
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 |  | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM20 |
| |  |  |  |  | | | Search ThermoFisher Antibodies for CEACAM20 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM20 |
| | | | LSBio Antibodies in human, mouse, rat for CEACAM20 |
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