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Aliases for CEACAM20 Gene

Aliases for CEACAM20 Gene

  • Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 2 3
  • GPAD9366 3
  • UNQ9366 3

External Ids for CEACAM20 Gene

Previous GeneCards Identifiers for CEACAM20 Gene

  • GC19M049698
  • GC19M045005
  • GC19M041442

Summaries for CEACAM20 Gene

GeneCards Summary for CEACAM20 Gene

CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEACAM20 Gene

Genomics for CEACAM20 Gene

Regulatory Elements for CEACAM20 Gene

Genomic Location for CEACAM20 Gene

Start:
44,501,677 bp from pter
End:
44,529,788 bp from pter
Size:
28,112 bases
Orientation:
Minus strand

Genomic View for CEACAM20 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CEACAM20 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEACAM20 Gene

Proteins for CEACAM20 Gene

  • Protein details for CEACAM20 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UY09-CEA20_HUMAN
    Recommended name:
    Carcinoembryonic antigen-related cell adhesion molecule 20
    Protein Accession:
    Q6UY09
    Secondary Accessions:

    Protein attributes for CEACAM20 Gene

    Size:
    585 amino acids
    Molecular mass:
    64502 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CEACAM20 Gene

Proteomics data for CEACAM20 Gene at MOPED

Post-translational modifications for CEACAM20 Gene

  • Glycosylation at Asn96, Asn105, Asn280, Asn306, Asn317, Asn368, and Asn415
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CEACAM20 Gene

Domains for CEACAM20 Gene

Gene Families for CEACAM20 Gene

HGNC:
  • IGD :Immunoglobulin superfamily / Immunoglobulin-like domain containing
  • ISET :Immunoglobulin superfamily / I-set domain containing

Protein Domains for CEACAM20 Gene

Graphical View of Domain Structure for InterPro Entry

Q6UY09

UniProtKB/Swiss-Prot:

CEA20_HUMAN :
  • Q6UY09
Domain:
  • Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
Family:
  • Belongs to the immunoglobulin superfamily. CEA family.
genes like me logo Genes that share domains with CEACAM20: view

Function for CEACAM20 Gene

Gene Ontology (GO) - Molecular Function for CEACAM20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with CEACAM20: view

Phenotypes for CEACAM20 Gene

GenomeRNAi human phenotypes for CEACAM20:
genes like me logo Genes that share phenotypes with CEACAM20: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CEACAM20

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CEACAM20 Gene

Localization for CEACAM20 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CEACAM20 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CEACAM20 Gene COMPARTMENTS Subcellular localization image for CEACAM20 gene
Compartment Confidence
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
extracellular 1
golgi apparatus 1
lysosome 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for CEACAM20 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CEACAM20: view

Pathways for CEACAM20 Gene

SuperPathways for CEACAM20 Gene

No Data Available

Interacting Proteins for CEACAM20 Gene

Gene Ontology (GO) - Biological Process for CEACAM20 Gene

None

No data available for Pathways by source for CEACAM20 Gene

Transcripts for CEACAM20 Gene

mRNA/cDNA for CEACAM20 Gene

(9) REFSEQ mRNAs :
(2) Selected AceView cDNA sequences:
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CEACAM20

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for CEACAM20
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CEACAM20 Gene

No ASD Table

Relevant External Links for CEACAM20 Gene

GeneLoc Exon Structure for
CEACAM20
ECgene alternative splicing isoforms for
CEACAM20

Expression for CEACAM20 Gene

mRNA expression in normal human tissues for CEACAM20 Gene

mRNA differential expression in normal tissues according to GTEx for CEACAM20 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (44.7) and Prostate (4.4).

SOURCE GeneReport for Unigene cluster for CEACAM20 Gene Hs.689632

genes like me logo Genes that share expressions with CEACAM20: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for CEACAM20 Gene

Orthologs for CEACAM20 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CEACAM20 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CEACAM20 35
  • 70.94 (n)
  • 54.9 (a)
dog
(Canis familiaris)
Mammalia CEACAM20 35
  • 75.03 (n)
  • 61.64 (a)
mouse
(Mus musculus)
Mammalia Ceacam20 35
  • 68.81 (n)
  • 57.32 (a)
Ceacam20 16
rat
(Rattus norvegicus)
Mammalia Ceacam20 35
  • 68.9 (n)
  • 57.5 (a)
zebrafish
(Danio rerio)
Actinopterygii zgc:198329 35
  • 43.37 (n)
  • 35.44 (a)
Species with no ortholog for CEACAM20:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CEACAM20 Gene

ENSEMBL:
Gene Tree for CEACAM20 (if available)
TreeFam:
Gene Tree for CEACAM20 (if available)

Paralogs for CEACAM20 Gene

Selected SIMAP similar genes for CEACAM20 Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with CEACAM20: view

No data available for Paralogs for CEACAM20 Gene

Variants for CEACAM20 Gene

Sequence variations from dbSNP and Humsavar for CEACAM20 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs687646 -- 44,510,555(+) AGGAA(A/G)GAAAG intron-variant
rs872327 -- 44,526,630(-) caaag(A/T)gctgg intron-variant
rs939902 -- 44,519,805(+) TTGCT(A/G)TGCCC intron-variant
rs1004605 -- 44,511,538(+) TGAAA(G/T)GTTTA intron-variant
rs1235376 -- 44,513,436(+) Ttttt(G/T)gtttt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CEACAM20 Gene

Variant ID Type Subtype PubMed ID
dgv3944n71 CNV Loss 21882294

Relevant External Links for CEACAM20 Gene

HapMap Linkage Disequilibrium report
CEACAM20

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CEACAM20 Gene

Disorders for CEACAM20 Gene

Relevant External Links for CEACAM20

Genetic Association Database (GAD)
CEACAM20
Human Genome Epidemiology (HuGE) Navigator
CEACAM20
genes like me logo Genes that share disorders with CEACAM20: view

No data available for UniProtKB/Swiss-Prot for CEACAM20 Gene

Publications for CEACAM20 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. Role of CEACAM1 and CEACAM20 in an in vitro model of prostate morphogenesis. (PMID: 23358633) Zhang H. … Shively J.E. (PLoS ONE 2013) 3
  4. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. (PMID: 16139472) Zebhauser R. … Zimmermann W. (Genomics 2005) 3

Products for CEACAM20 Gene

Sources for CEACAM20 Gene

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