CEACAM20 Gene
protein-coding GIFtS: 37
GCID: GC19M045005
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Carcinoembryonic Antigen-Related Cell Adhesion Molecule...
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Aliases
for CEACAM20 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb,
12H-InvDB,
13NCBI,
14NONCODE,
and/or 15RNAdb)
About This Section
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| Aliases |
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| Carcinoembryonic Antigen-Related Cell Adhesion Molecule 201 2 | | GPAD93662 | | UNQ93662 |
Export aliases for CEACAM20 gene to outside databasesPrevious GC identifers: GC19M049698 GC19M041442 |
Summaries
for CEACAM20 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
GeneCards Summary for CEACAM20 Gene: 
CEACAM20 (carcinoembryonic antigen-related cell adhesion molecule 20) is a protein-coding gene.
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Genomic Views
for CEACAM20 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 73),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.2 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CEACAM20 gene promoter:
Bach1 COUP-TF1 ER-alpha COUP Pax-2 HNF-4alpha2 Pax-2a Nkx5-1 HNF-4alpha1 COUP-TF
Other transcription factors
Search SABiosciences Chromatin IP Primers for CEACAM20
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEACAM20 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.31 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.31CEACAM20 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M045005: view genomic region
(about GC identifiers)
Start:
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45,005,729 bp from pter |
End:
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45,033,811 bp from pter |
Size:
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28,083 bases |
Orientation:
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minus strand |
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Proteins
for CEACAM20 gene
(According to
UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE 1MOPED,
2PaxDb, and 3MAXQB
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Cloud-Clone Corp.,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Cloud-Clone Corp.,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
LSBio,
Abcam, and/or
Cloud-Clone Corp.)
About This Section
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UniProtKB/Swiss-Prot: CEA20_HUMAN, Q6UY09 (See
protein sequence)Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 20 precursor Size: 585 amino acids; 64502 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)Explore the universe of human proteins at neXtProt for CEACAM20: NX_Q6UY09
Post-translational modifications:
View modification sites using PhosphoSitePlusView neXtProt modification sites for NX_Q6UY09
CEACAM20 Protein expression data from MOPED1, PaxDb2 and
MAXQB3 : --
REFSEQ proteins (4 alternative transcripts):
NP_001096067.1 NP_001096068.1 NP_001096069.1 NP_001096070.1
Human Recombinant Protein Products for CEACAM20:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0016021 | integral to membrane |
IEA | -- |
CEACAM20 for ontologies About GeneDecksing
CEACAM20 Antibody Products:
Assay Products for CEACAM20: |
Protein
Domains /
Families
for CEACAM20 gene(According to HGNC, IUPHAR, InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| HGNC Gene Families:
ISET: Immunoglobulin superfamily / I-set domain containingIGD: Immunoglobulin superfamily / Immunoglobulin-like domain containing
5 InterPro protein domains:Graphical View of Domain Structure for InterPro Entry Q6UY09ProtoNet protein and cluster: Q6UY09 UniProtKB/Swiss-Prot: CEA20_HUMAN, Q6UY09Similarity: Belongs to the immunoglobulin superfamily. CEA familySimilarity: Contains 4 Ig-like C2-type (immunoglobulin-like) domains
CEACAM20 for domains About GeneDecksing
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Function
for CEACAM20 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
genOway,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
Vector BioLabs,
and Sirion Biotech,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene.)
About This Section
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Phenotypes:
1 GenomeRNAi human phenotype for CEACAM20:
Animal Models:
Cell Line
Products: |  | GenScript Custom overexpressing Cell Line Services for CEACAM20 | |  | Search LifeMap BioReagents cell lines for CEACAM20 | In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM20 |
Pathways & Interactions
for CEACAM20 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Sino Biological,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene).
About This Section
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Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CEACAM20
|
Drugs & Compounds
for CEACAM20 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek,
Ligands according to IUPHAR,
and Drugs according to DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
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 Browse Tocris compounds for CEACAM20 (CEA20)
Search CenterWatch for drugs/clinical trials and news about CEACAM20 / CEA20
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Transcripts
for CEACAM20 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
Conferences by KenesGroup,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Sirion Biotech,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
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REFSEQ mRNAs for CEACAM20 gene (5 alternative transcripts): NM_001102597.1 NM_198444.1 NM_001102598.1 NM_001102599.1 NM_001102600.1 Unigene Cluster for CEACAM20: Carcinoembryonic antigen-related cell adhesion molecule 20 Hs.689632 Unigene Representative Sequence: AY3581299 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000454753 ENST00000421432(uc010ejq.1) ENST00000448350 ENST00000431738
ENST00000414638 ENST00000445209(uc010ejn.1) ENST00000412211(uc010ejo.1)
ENST00000424903(uc010ejp.1) ENST00000316962
Primer
Products: |  | OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM20
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CEACAM20 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM20 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM20 |
Additional mRNA sequence: AY358129.1 EU008600.1 EU008601.1 EU008602.1 EU008603.1 2 AceView cDNA sequences: AY358129 NM_198444
GeneLoc Exon Structure
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Expression
for CEACAM20 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CEACAM20 expression in normal human tissues
(normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
About this image
SOURCE GeneReport for Unigene cluster: Hs.689632
SABiosciences Custom PCR Arrays for CEACAM20
Primer
Products: | | OriGene qSTAR qPCR primer pairs in human, mouse for CEACAM20
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CEACAM20 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM20 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM20 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM20 |
Orthologs
for CEACAM20 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of human and mouse.
Orthologs for CEACAM20 gene from 1/3 species (see all 3) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ceacam201 , 5 |
carcinoembryonic antigen-related cell adhesion molecule more1, 5 |
69.6(n)1
58.35(a)1 |
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7 (9.96 cM)5
716011 NM_027839.21 NP_082115.21
199654125 |
ENSEMBL Gene Tree for CEACAM20 (if available)
TreeFam Gene Tree for CEACAM20 (if available) |
Paralogs
for CEACAM20 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CEACAM20 gene
3 SIMAP similar genes for CEACAM20 using alignment to 5 protein entries: CEA20_HUMAN (see all proteins):CEACAM1 PSGII PSG1
CEACAM20 for paralogs About GeneDecksing
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Genomic Variants
for CEACAM20 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
4UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
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| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CEACAM20 (45005729 - 45033811 bp)
Structural Variations
Database of Genomic Variants (DGV) 1 variation for CEACAM20: About this table 
| | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CEACAM20 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Conferences by KenesGroup,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 CEACAM20 for disorders About MalaCards
CEACAM20 for disorders About GeneDecksing
Genetic Association Database (GAD): CEACAM20
Human Genome Epidemiology (HuGE) Navigator: CEACAM20 (1 document)
Export disorders for CEACAM20 gene to outside databases
|
Publications
for CEACAM20 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CEACAM20 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CEACAM20) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
- Role of CEACAM1 and CEACAM20 in an in vitro model of p rostate morphogenesis. (PubMed id 23358633)1 Zhang H....Shively J.E. (2013)
- Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. (PubMed id 16139472)1 Zebhauser R....Zimmermann W. (2005)
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External Searches for CEACAM20 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing CEACAM20 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing CEACAM20 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CEACAM20 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CEACAM20 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for CEACAM20 gene:
Search GeneIP for patents involving CEACAM20
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CEACAM20 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory,
genOway)
About This Section
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|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CEACAM20 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CEACAM20 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEACAM20 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEACAM20 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM20 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM20 |
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 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM20 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for CEACAM20 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CEACAM20 |
| |  |  |  | | | | LSBio Antibodies in human, mouse, rat for CEACAM20 |
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