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Aliases for CEACAM18 Gene

Aliases for CEACAM18 Gene

  • Carcinoembryonic Antigen Related Cell Adhesion Molecule 18 2 3
  • Carcinoembryonic Antigen-Related Cell Adhesion Molecule 18 2 5

External Ids for CEACAM18 Gene

Previous GeneCards Identifiers for CEACAM18 Gene

  • GC19U900557
  • GC19P056674
  • GC19P051979
  • GC19P048311

Summaries for CEACAM18 Gene

GeneCards Summary for CEACAM18 Gene

CEACAM18 (Carcinoembryonic Antigen Related Cell Adhesion Molecule 18) is a Protein Coding gene. An important paralog of this gene is CEACAM8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CEACAM18 Gene

Genomics for CEACAM18 Gene

Regulatory Elements for CEACAM18 Gene

Enhancers for CEACAM18 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CEACAM18 on UCSC Golden Path with GeneCards custom track

Genomic Location for CEACAM18 Gene

Chromosome:
19
Start:
51,478,547 bp from pter
End:
51,491,261 bp from pter
Size:
12,715 bases
Orientation:
Plus strand

Genomic View for CEACAM18 Gene

Genes around CEACAM18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CEACAM18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CEACAM18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CEACAM18 Gene

Proteins for CEACAM18 Gene

  • Protein details for CEACAM18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MTB9-CEA18_HUMAN
    Recommended name:
    Carcinoembryonic antigen-related cell adhesion molecule 18
    Protein Accession:
    A8MTB9
    Secondary Accessions:
    • C9JN24

    Protein attributes for CEACAM18 Gene

    Size:
    384 amino acids
    Molecular mass:
    43320 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CEACAM18 Gene

Proteomics data for CEACAM18 Gene at MOPED

Post-translational modifications for CEACAM18 Gene

  • Glycosylation at Asn 108, Asn 112, Asn 121, Asn 162, and Asn 270

Other Protein References for CEACAM18 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CEACAM18 Gene

Domains & Families for CEACAM18 Gene

Protein Domains for CEACAM18 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CEACAM18 Gene

Graphical View of Domain Structure for InterPro Entry

A8MTB9

UniProtKB/Swiss-Prot:

CEA18_HUMAN :
  • Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
  • Belongs to the immunoglobulin superfamily. CEA family.
Domain:
  • Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Family:
  • Belongs to the immunoglobulin superfamily. CEA family.
genes like me logo Genes that share domains with CEACAM18: view

Function for CEACAM18 Gene

Phenotypes for CEACAM18 Gene

GenomeRNAi human phenotypes for CEACAM18:
genes like me logo Genes that share phenotypes with CEACAM18: view

Animal Model Products

  • Taconic Biosciences Mouse Models for CEACAM18

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CEACAM18 Gene

Localization for CEACAM18 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CEACAM18 Gene COMPARTMENTS Subcellular localization image for CEACAM18 gene
Compartment Confidence
cytosol 2
nucleus 2
plasma membrane 2
endoplasmic reticulum 1
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CEACAM18 Gene

Pathways & Interactions for CEACAM18 Gene

SuperPathways for CEACAM18 Gene

No Data Available

Interacting Proteins for CEACAM18 Gene

Gene Ontology (GO) - Biological Process for CEACAM18 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CEACAM18 Gene

Drugs & Compounds for CEACAM18 Gene

No Compound Related Data Available

Transcripts for CEACAM18 Gene

mRNA/cDNA for CEACAM18 Gene

(3) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CEACAM18 Gene

No ASD Table

Relevant External Links for CEACAM18 Gene

GeneLoc Exon Structure for
CEACAM18
ECgene alternative splicing isoforms for
CEACAM18

Expression for CEACAM18 Gene

mRNA expression in normal human tissues for CEACAM18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CEACAM18 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (x50.6).

SOURCE GeneReport for Unigene cluster for CEACAM18 Gene Hs.653111

genes like me logo Genes that share expression patterns with CEACAM18: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CEACAM18 Gene

Orthologs for CEACAM18 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CEACAM18 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC615876 35
  • 73.28 (n)
  • 57.85 (a)
CEACAM18 36
  • 55 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC484346 35
  • 73.28 (n)
  • 58.97 (a)
CEACAM18 36
  • 52 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ceacam18 35
  • 71.19 (n)
  • 61.22 (a)
Ceacam18 16
Ceacam18 36
  • 55 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CEACAM18 35
  • 98.27 (n)
  • 96.54 (a)
CEACAM18 36
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Ceacam18 35
  • 69.95 (n)
  • 59.56 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 24 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 29 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 9 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ceacam1 36
  • 5 (a)
ManyToMany
cxcr3.1 36
  • 15 (a)
ManyToMany
si:ch211-264f5.6 36
  • 12 (a)
ManyToMany
si:dkey-11o1.2 36
  • 19 (a)
ManyToMany
si:dkey-11o1.3 36
  • 14 (a)
ManyToMany
si:dkey-250k15.10 36
  • 16 (a)
ManyToMany
si:dkey-250k15.7 36
  • 13 (a)
ManyToMany
si:dkey-250k15.9 36
  • 18 (a)
ManyToMany
Species with no ortholog for CEACAM18:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CEACAM18 Gene

ENSEMBL:
Gene Tree for CEACAM18 (if available)
TreeFam:
Gene Tree for CEACAM18 (if available)

Paralogs for CEACAM18 Gene

(4) SIMAP similar genes for CEACAM18 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for CEACAM18 Gene

genes like me logo Genes that share paralogs with CEACAM18: view

Variants for CEACAM18 Gene

Sequence variations from dbSNP and Humsavar for CEACAM18 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs8106673 - 51,481,471(+) CTGCC(A/T)CACAA reference, missense
rs12610545 - 51,481,473(+) GCCTC(A/G)CAAAT reference, missense
rs8100294 -- 51,483,335(+) ACATC(C/T)CCCTG intron-variant
rs8100959 -- 51,479,907(+) TGTGC(A/T)CCACA intron-variant
rs8101768 -- 51,479,780(+) GAAGG(C/T)GTGGT intron-variant

Variation tolerance for CEACAM18 Gene

Gene Damage Index Score: 6.84; 79.29% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CEACAM18 Gene

Disorders for CEACAM18 Gene

Relevant External Links for CEACAM18

Genetic Association Database (GAD)
CEACAM18
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CEACAM18

No disorders were found for CEACAM18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CEACAM18 Gene

Publications for CEACAM18 Gene

  1. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. (PMID: 16139472) Zebhauser R. … Zimmermann W. (Genomics 2005) 3 67

Products for CEACAM18 Gene

Sources for CEACAM18 Gene

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