CEACAM18 Gene
protein-coding GIFtS: 29
GCID: GC19P051979
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carcinoembryonic antigen-related cell adhesion molecule...
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Aliases
for CEACAM18 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Carcinoembryonic Antigen-Related Cell Adhesion Molecule 181 2 |
Export aliases for CEACAM18 gene to outside databasesPrevious GC identifers: GC19U900557 GC19P056674 GC19P048311 |
Summaries
for CEACAM18 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CEACAM18 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CEACAM18 gene promoter:
HOXA9B RelA NF-kappaB Tal-1beta E47 RORalpha1 ARP-1 c-Myb NF-kappaB1 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CEACAM18
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEACAM18 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.41 Ensembl cytogenetic band: 19q13.41 HGNC cytogenetic band: 19q13.41CEACAM18 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P051979: view genomic region
(about GC identifiers)
Start:
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51,979,838 bp from pter |
End:
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51,986,611 bp from pter |
Size:
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6,774 bases |
Orientation:
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plus strand |
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Proteins
for CEACAM18 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CEA18_HUMAN, A8MTB9 (See
protein sequence)Recommended Name: Carcinoembryonic antigen-related cell adhesion molecule 18 Size: 398 amino acids; 44060 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: C9JN24Explore the universe of human proteins at neXtProt for CEACAM18: NX_A8MTB9
CEACAM18 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001073874.1
ENSEMBL proteins: ENSP00000379738 ENSP00000402203
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
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| GO:0016021 | integral to membrane |
IEA | -- |
CEACAM18 for ontologies About GeneDecksing
CEACAM18 Antibody Products:
Assay Products for CEACAM18: |
Protein
Domains /
Families
for CEACAM18 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CEACAM18 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A8MTB9ProtoNet protein and cluster: A8MTB9 UniProtKB/Swiss-Prot: CEA18_HUMAN, A8MTB9Similarity: Belongs to the immunoglobulin superfamily. CEA familySimilarity: Contains 1 Ig-like C2-type (immunoglobulin-like) domain |
Function
for CEACAM18 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM18 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CEACAM18 (NM_001080405) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CEACAM18 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CEACAM18 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM18 |
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Pathways & Interactions
for CEACAM18 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CEACAM18
|
Drugs & Compounds
for CEACAM18 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CEACAM18
Search CenterWatch for drugs/clinical trials and news about CEACAM18 / CEA18
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Transcripts
for CEACAM18 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CEACAM18 gene: NM_001080405.1 Unigene Cluster for CEACAM18: Carcinoembryonic antigen-related cell adhesion molecule 18 Hs.653111 Unigene Representative Sequence: NM_0010804052 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000396477 ENST00000451626(uc002pwv.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM18 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM18
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CEACAM18 (NM_001080405) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CEACAM18 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CEACAM18 |
GeneLoc Exon Structure
|
Expression
for CEACAM18 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CEACAM18 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTGCACAT
About this image
See CEACAM18 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.653111
SABiosciences Custom PCR Arrays for CEACAM18
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CEACAM18
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CEACAM18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM18 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM18 |
Orthologs
for CEACAM18 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CEACAM18 gene from 3/7 species (see all 7) About this table
ENSEMBL Gene Tree for CEACAM18 (if available)
TreeFam Gene Tree for CEACAM18 (if available) |
Paralogs
for CEACAM18 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CEACAM18 gene
- PSG92 PSG82 CEACAM42 CEACAM52 PSG112 CEACAM72 PSG32 CEACAM212
- PSG12 PSG52 PSG62 CEACAM12 CEACAM82 PSG22 CEACAM62 CEACAM162
- PSG42 CEACAM32
1 SIMAP similar gene for CEACAM18 using alignment to 2 protein entries: CEA18_HUMAN (see all proteins):CEA
CEACAM18 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CEACAM18
PGOHUM00000234374
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Genomic Variants
for CEACAM18 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for CEACAM18 (51979838 - 51986611 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CEACAM18: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CEACAM18 |
|
Disorders
/ Diseases
for CEACAM18 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CEACAM18 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CEACAM18 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CEACAM18) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. (PubMed id 16139472)1 Zebhauser R....Zimmermann W. (2005)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
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External Searches for CEACAM18 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing CEACAM18 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CEACAM18 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CEACAM18 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CEACAM18 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for CEACAM18 gene:
Search GeneIP for patents involving CEACAM18
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CEACAM18 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CEACAM18 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CEACAM18 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CEACAM18 | | | OriGene Protein Over-expression Lysate for CEACAM18 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CEACAM18 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM18 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CEACAM18 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CEACAM18 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CEACAM18 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CEACAM18 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CEACAM18 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CEACAM18 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CEACAM18 |
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 | | | CEACAM18 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CEACAM18 |
|  |  |  | | | | Search ThermoFisher Antibodies for CEACAM18 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat CEACAM18 |
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