CDYL2 Gene
protein-coding GIFtS : 45 GCID: GC16 M080637
chromodomain protein, Y-like 2 chromodomain Y-like protein 2 )
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Aliasesfor CDYL2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Chromodomain Protein, Y-Like 2 1 2 Chromodomain Y-Like Protein 21 2 CDY-Like 22 3 FLJ388661 PCCP12 Prostate Cancer Candidate Protein 1, PCCP12
Export aliases for CDYL2 gene to outside databases Previous GC identifers: GC16M080376 GC16M080417 GC16M079195 GC16M066394
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Summariesfor CDYL2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
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Genomic Viewsfor CDYL2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000016.9 NC_018927.1 NT_010498.15 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CDYL2 gene promoter:Oct-B1 oct-B3 oct-B2 Lmo2 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 POU2F1 POU2F1a Pax-4a Other transcription factors Search SABiosciences Chromatin IP Primers for CDYL2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 16q23.2 Ensembl cytogenetic band: 16q23.2 HGNC cytogenetic band: 16q23.2 CDYL2 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 16 GeneLoc Exon Structure
GeneLoc location for GC16M080637: view genomic region
(about GC identifiers )
Start: 80,637,609 bp from pter End:
80,838,226 bp from pter
Size: 200,618 bases Orientation:
minus strand
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Proteinsfor CDYL2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: CDYL2_HUMAN, Q8N8U2 See
protein sequence )Recommended Name: Size : 506 amino acids; 56500 DaSubcellular location : Nucleus (By similarity)1 PDB 3D structure from :4HAE (3D) Secondary accessions : Q7Z5I8Explore the universe of human proteins at neXtProt for CDYL2: NX_Q8N8U2 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8N8U2 CDYL2 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_689555.2 ENSEMBL proteins: ENSP00000299564 ENSP00000454546 ENSP00000455111 ENSP00000456934 ENSP00000456498 Human Recombinant Protein Products: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005634 nucleus
IEA --
About GeneDecksing CDYL2 Antibody Products: Assay Products for CDYL2:
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Protein
Domains /for CDYL2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 5 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8N8U2 ProtoNet protein and cluster: Q8N8U2
1 Blocks protein family : IPB000953 UniProtKB/Swiss-Prot: CDYL2_HUMAN, Q8N8U2 Similarity : Contains 1 chromo domain
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Functionfor CDYL2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: CDYL2 (NM_152342 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDYL2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CDYL2
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDYL2
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view) : About this table
About GeneDecksing 2 GenomeRNAi human phenotypes for CDYL2 :Animal Models: 1 MGI phenotypic allele Cdyl2 (no phenotypes)About GeneDecksing
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Pathways & Interactionsfor CDYL2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDYL2
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Drugs & Compoundsfor CDYL2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for CDYL2 CDYL2
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Transcriptsfor CDYL2 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
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QIAGEN
)About This Section REFSEQ mRNAs for CDYL2 gene: NM_152342.2 Unigene Cluster for CDYL2:
Chromodomain protein, Y-like 2 Hs.373908 [show with all ESTs ] Unigene Representative Sequence: NM_152342 7 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000299564 (uc002ffs.3 ) ENST00000562812 ENST00000563890 ENST00000566173 ENST00000561616 ENST00000567924 ENST00000562753 Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: CDYL2 (NM_152342 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDYL2 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CDYL2
Additional cDNA sequence: AK096185.1 AY273798.1 BC069440.1 BC100803.1 BC100804.1 BC100805.1 BC100806.1
3 DOTS entries : DT.91706200 DT.120684277
DT.91707287 19 AceView cDNA sequences :
CR616267 AK096185 NM_152342 AX781671 BC069440 BX951358 AI024821 BX335007 AX781675 BX390259 AY273798 BX108447 AX781670 BF896769 AI801860 BX335006 R70879 AW897682 BG010766 GeneLoc Exon Structure
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Expression for CDYL2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section CDYL2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image CDYL2 expression in embryonic tissues and stem cells About this table 1 LifeMap In Vivo Development Anatomical Compartment/CellTissue Category (developmental path) Heart Endocardium Endocardial Tube Cells Endocardium Expression: Experimental details:
In-situ hybridization
See CDYL2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CDYL2 SOURCE GeneReport for Unigene cluster: Hs.373908 UniProtKB/Swiss-Prot: CDYL2_HUMAN, Q8N8U2 Tissue specificity : Ubiquitously expressedSABiosciences Expression via Pathway-Focused PCR Array including CDYL2 : Epigenetic Chromatin Remodeling Factors in human mouse rat
Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDYL2
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Orthologsfor CDYL2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for CDYL2 gene from 8/25 species (see all 25 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves CDYL21
chromodomain protein, Y-like 2
74.22(n) 85.77(a)
425886 XM_423582.3 XP_423582.3
lizard Reptilia CDYL26 6
--
75(a) 16(a)
1 ↔ 1possible ortholog
LGc(5620828-5645096) GL343681.1(204801-230877)
zebrafish Actinopterygii echdc16
enoyl Coenzyme A hydratase domain containing 1
18(a)
possible ortholog
16(6495161-6506141)
fruit fly Insecta CG138906
--
24(a)
possible ortholog
3L(851346-852673)
worm Secernentea B0272.46 6
Protein C32E8.9
27(a) 14(a)
1 ↔ manypossible ortholog
X(9428372-9430264) I(3794556-3798056)
thale cress eudicotyledons ECHIA6
enoyl-CoA hydratase
19(a)
possible ortholog
4(9176673-9178048)
rice Liliopsida --
enoyl-CoA hydratase/isomerase family protein, puta... 17(a)
possible ortholog
3(11067660-11070152)
E. coli Gamma proteobacteria paaG6
1,2-epoxyphenylacetyl-CoA isomerase, oxepin-CoA-fo... 19(a)
possible ortholog
Chromosome(1456288-1457076)
ENSEMBL Gene Tree for CDYL2 (if available)TreeFam Gene Tree for CDYL2 (if available)
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Paralogsfor CDYL2 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for CDYL2 gene CDY2A 2 ECI2 2 CDY2B 2 CDYL 2 CDY1 2 CDY1B 2 8 SIMAP similar genes for CDYL2 using alignment to 2 protein entries: CDYL2_HUMAN (see all proteins ):CDYL CDY2B CBX5 CDY1 CDY1B CDY2A ECI2 CBX1 About GeneDecksing
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Genomic Variantsfor CDYL2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 16 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for CDYL2 (80637609 - 80838226 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 5 variations for CDYL2 3 CNVs 102342 7133 72628 1 Indel 72630 1 Inversion 103339
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor CDYL2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing 8 : About MalaCards prostate cancer prostatitis hepatitis b kidney disease hepatocellular carcinoma hepatitis cholesterol carcinoma Human Genome Epidemiology (HuGE) Navigator: CDYL2 (5 documents) Export disorders for CDYL2 gene to outside databases
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Publicationsfor CDYL2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for CDYL2 gene, integrated from 9 sources (see all 14 ):(articles sorted by number of sources associating them with CDYL2) Utopia : connect your pdf to the dynamic
The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence. (PubMed id 12837688) 1 , 2 , 3(2003) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296) 1 (2010) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 (2010) Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315) 1 (2010) Fine mapping and association studies of a high-densit y lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian su bjects. (PubMed id 19844255) 1 (2010) Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895) 1 (2009) The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing. (PubMed id 17577209) 1 (2007) hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965) 1 (2007) The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553) 2 (2004)
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External Searches for CDYL2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing CDYL2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing CDYL2 gene
(According to HUGE )
About This Section --
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Specialized Databases showing CDYL2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for CDYL2 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for CDYL2 gene: CDYL2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor CDYL2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for CDYL2 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat OriGene Protein Over-expression Lysate for CDYL2 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for CDYL2 OriGene 3'-UTR Clone for CDYL2 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for CDYL2 OriGene Custom Protein Services for CDYL2 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDYL2 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Search Tocris compounds for CDYL2
CDYL2 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDYL2
Search ThermoFisher Antibodies for CDYL2
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat CDYL2
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Aliases for CDYL2
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Disorders / Diseases for CDYL2
Domains / Families for CDYL2
Drugs / Compounds for CDYL2
Expression for CDYL2
Function for CDYL2
Genomic Views for CDYL2
Intellectual Property for CDYL2
Orthologs for CDYL2
Paralogs for CDYL2
Pathways / Interactions for CDYL2
Products for CDYL2
Proteins for CDYL2
Publications for CDYL2
Search Box for CDYL2
Summaries for CDYL2
Transcripts for CDYL2
Variants for CDYL2
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BOTTOM
and Proteopedia 
for CDYL2:
Browse Tocris compounds for 
Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
In-situ hybridization
