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CDYL2 Gene

protein-coding   GIFtS: 44
GCID: GC16M080637

Chromodomain Protein, Y-Like 2

(Previous name: chromodomain Y-like protein 2)
  See CDYL2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Chromodomain Protein, Y-Like 21 2
Chromodomain Y-Like Protein 21 2
CDY-Like 22 3
PCCP12
Prostate Cancer Candidate Protein 1, PCCP12

External Ids:    HGNC: 230301   Entrez Gene: 1243592   Ensembl: ENSG000001664467   UniProtKB: Q8N8U23   

Export aliases for CDYL2 gene to outside databases

Previous GC identifers: GC16M080376 GC16M080417 GC16M079195 GC16M066394


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CDYL2 Gene:
CDYL2 (chromodomain protein, Y-like 2) is a protein-coding gene. Diseases associated with CDYL2 include prostate cancer. GO annotations related to this gene include methylated histone residue binding. An important paralog of this gene is CDY2A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000016.10  NC_018927.2  NT_010498.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the CDYL2 gene promoter:
         Oct-B1   oct-B3   oct-B2   Lmo2   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   POU2F1   POU2F1a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDYL2 promoter sequence
   Search Chromatin IP Primers for CDYL2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CDYL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.2   Ensembl cytogenetic band:  16q23.2   HGNC cytogenetic band: 16q23.2

CDYL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDYL2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M080637:  view genomic region     (about GC identifiers)

Start:
80,631,803 bp from pter      End:
80,838,226 bp from pter
Size:
206,424 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CDYL2_HUMAN, Q8N8U2 (See protein sequence)
Recommended Name: Chromodomain Y-like protein 2  
Size: 506 amino acids; 56500 Da
Subunit: Interacts (via chromo domain) with histone H3K9me3 (By similarity)
1 PDB 3D structure from and Proteopedia for CDYL2:
4HAE (3D)    
Secondary accessions: Q7Z5I8

Explore the universe of human proteins at neXtProt for CDYL2: NX_Q8N8U2

Explore proteomics data for CDYL2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CDYL2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689555.2  
    ENSEMBL proteins: 
     ENSP00000476295   ENSP00000454546   ENSP00000455111   ENSP00000456934   ENSP00000456498  

    CDYL2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for CDYL2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for CDYL2
    GenScript Custom Purified and Recombinant Proteins Services for CDYL2
    Novus Biologicals CDYL2 Protein
    Novus Biologicals CDYL2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CDYL2

     
    Search eBioscience for Proteins for CDYL2 

    CDYL2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals CDYL2 Antibodies
    Abcam antibodies for CDYL2
    Cloud-Clone Corp. Antibodies for CDYL2
    Search ThermoFisher Antibodies for CDYL2
    LSBio Antibodies in human, mouse, rat for CDYL2

    CDYL2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CDYL2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CDYL2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CDYL2
    Cloud-Clone Corp. CLIAs for CDYL2
    Search eBioscience for ELISAs for CDYL2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR000953 Chromo_domain/shadow
     IPR023780 Chromo_domain
     IPR016197 Chromodomain-like
     IPR023779 Chromodomain_CS
     IPR001753 Crotonase_core_superfam

    Graphical View of Domain Structure for InterPro Entry Q8N8U2

    ProtoNet protein and cluster: Q8N8U2

    1 Blocks protein domain: IPB000953 Chromo domain

    UniProtKB/Swiss-Prot: CDYL2_HUMAN, Q8N8U2
    Similarity: Contains 1 chromo domain


    Find genes that share domains with CDYL2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity IEA--
    GO:0005515protein binding IPI17577209
    GO:0035064methylated histone residue binding IEA--
         
    Find genes that share ontologies with CDYL2           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for CDYL2:
     Increased G2M DNA content, inc  Increased number of mitotic ce 

         1 MGI phenotypic allele for Cdyl2 (no phenotypes)

    Find genes that share phenotypes with CDYL2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CDYL2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CDYL2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDYL2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CDYL2

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CDYL2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CDYL2 (see all 18):
    hsa-miR-495 hsa-miR-875-3p hsa-miR-515-5p hsa-miR-629 hsa-miR-7-1* hsa-miR-34b hsa-miR-18b* hsa-miR-4293
    SwitchGear 3'UTR luciferase reporter plasmidCDYL2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CDYL2
    Predesigned siRNA for gene silencing in human, mouse, rat CDYL2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CDYL2

    Clone
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    OriGene clones in human, mouse for CDYL2 (see all 6)
    OriGene ORF clones in mouse, rat for CDYL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CDYL2 (NM_152342)
    Sino Biological Human cDNA Clone for CDYL2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CDYL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDYL2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CDYL2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDYL2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CDYL2_HUMAN, Q8N8U2: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with CDYL2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including CDYL2: 
              Epigenetic Chromatin Remodeling Factors in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for CDYL2

    1 Interacting protein for CDYL2 (Q8N8U21) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRMT5O147441EBI-8467076,EBI-351098
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----

    Find genes that share ontologies with CDYL2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CDYL2



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CDYL2 gene: 
    NM_152342.2  

    Unigene Cluster for CDYL2:

    Chromodomain protein, Y-like 2
    Hs.373908  [show with all ESTs]
    Unigene Representative Sequence: NM_152342
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000570137 ENST00000562812 ENST00000563890 ENST00000566173 ENST00000561616
    ENST00000567924 ENST00000562753
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CDYL2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate CDYL2 (see all 18):
    hsa-miR-495 hsa-miR-875-3p hsa-miR-515-5p hsa-miR-629 hsa-miR-7-1* hsa-miR-34b hsa-miR-18b* hsa-miR-4293
    SwitchGear 3'UTR luciferase reporter plasmidCDYL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CDYL2
    Predesigned siRNA for gene silencing in human, mouse, rat CDYL2
    Clone
    Products:
         
    OriGene clones in human, mouse for CDYL2 (see all 6)
    OriGene ORF clones in mouse, rat for CDYL2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CDYL2 (NM_152342)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CDYL2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDYL2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for CDYL2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CDYL2
      QuantiTect SYBR Green Assays in human, mouse, rat CDYL2
      QuantiFast Probe-based Assays in human, mouse, rat CDYL2

    Additional mRNA sequence: 

    AK096185.1 AY273798.1 BC069440.1 BC100803.1 BC100804.1 BC100805.1 BC100806.1 

    3 DOTS entries:

    DT.91706200  DT.120684277  DT.91707287 

    19 AceView cDNA sequences:

    CR616267 AK096185 BC069440 BX951358 NM_152342 AX781671 BX108447 AI024821 
    BX390259 BX335007 BF896769 AX781675 AY273798 AI801860 AX781670 BX335006 
    AW897682 R70879 BG010766 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CDYL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CDYL2 Expression
    About this image

    CDYL2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CDYL2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.373908

    UniProtKB/Swiss-Prot: CDYL2_HUMAN, Q8N8U2
    Tissue specificity: Ubiquitously expressed

        Pathway & Disease-focused RT2 Profiler PCR Array including CDYL2: 
              Epigenetic Chromatin Remodeling Factors in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for CDYL2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CDYL2
    QuantiTect SYBR Green Assays in human, mouse, rat CDYL2
    QuantiFast Probe-based Assays in human, mouse, rat CDYL2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDYL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CDYL2 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdyl21 , 5 chromodomain protein, Y chromosome-like 21, 5 85.75(n)1
    92.05(a)1
      8 (63.15 cM)5
    757961  NM_029441.31  NP_083717.11 
     1165687245 
    chicken
    (Gallus gallus)
    Aves CDYL21 chromodomain protein, Y-like 2 74.22(n)
    85.77(a)
      425886  XM_423582.4  XP_423582.3 
    lizard
    (Anolis carolinensis)
    Reptilia CDYL26
    chromodomain protein, Y-like 2
    86(a)
    1 ↔ 1
    LGc(5594613-5645096)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cdyl21 chromodomain protein, Y-like 2 71.49(n)
    81.93(a)
      100486281  XM_002938138.2  XP_002938184.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG36806
    --
    11(a)
    1 → many
    3L(20802769-20806432)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DCI16
    ECI16
    Peroxisomal protein; identification as a delta(3,5...
    Peroxisomal delta3,delta2-enoyl-CoA isomerase, hex...
    24(a)
    21(a)
    many ↔ many
    many ↔ many
    XV(674352-675167) YOR180C
    XII(706198-707040) YLR284C


    ENSEMBL Gene Tree for CDYL2 (if available)
    TreeFam Gene Tree for CDYL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CDYL2 gene
    CDY2A2  ECI22  CDY2B2  AUH2  ECHDC32  ECHS12  CDY1B2  ECHDC22  
    CDYL2  ECH12  CDY12  
    8 SIMAP similar genes for CDYL2 using alignment to 2 protein entries:     CDYL2_HUMAN (see all proteins):
    CDYL    CDY2B    CBX5    CDY1    CDY1B    CDY2A
    ECI2    CBX1

    Find genes that share paralogs with CDYL2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CDYL2 (see all 6077)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs773294151,2
    C,F--80637311(+) CCCAAG/TATGTC 1 -- ds50011Minor allele frequency- T:0.17WA 118
    rs1404113261,2
    --80637326(+) AAGGAA/CAAACC 1 -- ds50010--------
    rs1838727431,2
    C--80637365(+) TGAGAA/CCCGTT 1 -- ds50010--------
    rs800416531,2
    F--80637368(+) GAACCG/ATTTTA 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs1884727391,2
    --80637455(+) GTTCAC/TTGCTA 1 -- ds50010--------
    rs1455109371,2
    C--80637537(+) CAACAG/TACATC 1 -- ds50010--------
    rs1378947541,2
    --80637569(+) ATAAAC/TAAAAC 1 -- ds50010--------
    rs728241171,2
    C,F--80637571(+) AAATAA/GAACAA 1 -- ds50011Minor allele frequency- G:0.03NA 120
    rs1407636161,2
    --80637644(+) ATACAC/TATAAA 1 -- ds50010--------
    rs1920303951,2
    --80637739(+) ACTCAA/GTTGGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for CDYL2 (80631803 - 80838226 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CDYL2 (see all 15):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2673789CNV Deletion23128226
    esv2675473CNV Deletion23128226
    esv2618788CNV Insertion19546169
    esv268803CNV Insertion20981092
    esv273920CNV Insertion20981092
    esv26401CNV Loss19812545
    nsv457560CNV Loss19166990
    esv33408CNV Loss17666407
    nsv525885CNV Loss19592680
    nsv521339CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CDYL2
    DNA2.0 Custom Variant and Variant Library Synthesis for CDYL2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for CDYL2:    
    About MalaCards
    prostate cancer


    Find genes that share disorders with CDYL2           About GenesLikeMe

    Genetic Association Database (GAD): CDYL2
    Human Genome Epidemiology (HuGE) Navigator: CDYL2 (5 documents)

    Export disorders for CDYL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CDYL2 gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with CDYL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The CDY-related gene family: coordinated evolution in copy number, expression profile and protein sequence. (PubMed id 12837688)1, 2, 3 Dorus S.... Lahn B.T. (Hum. Mol. Genet. 2003)
    2. Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (Am. J. Hypertens. 2010)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. (PubMed id 19844255)1, 4 Dastani Z....Genest J. (Eur. J. Hum. Genet. 2010)
    5. Association of genetic variants with hemorrhagic stroke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2010)
    6. Association of gene polymorphisms with chronic kidney disease in Japanese individuals. (PubMed id 19724895)1, 4 Yoshida T....Yamada Y. (Int. J. Mol. Med. 2009)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Large-scale genotyping identifies 41 new loci associated with breast cancer risk. (PubMed id 23535729)1 Michailidou K....Easton D.F. (Nat. Genet. 2013)
    9. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    10. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
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      Query String
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 124359 HGNC: 23030 AceView: CDYL2 Ensembl:ENSG00000166446 euGenes: HUgn124359
    ECgene: CDYL2 H-InvDB: CDYL2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CDYL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CDYL2 gene:
    Search GeneIP for patents involving CDYL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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