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Aliases for CDV3 Gene

Aliases for CDV3 Gene

  • CDV3 Homolog 2 3
  • CDV3 Homolog (Mouse) 2 5
  • H41 3 4
  • Carnitine Deficiency-Associated Gene Expressed In Ventricle 3 (Mouse) 2
  • Carnitine Deficiency-Associated Gene Expressed In Ventricle 3 3

External Ids for CDV3 Gene

Previous GeneCards Identifiers for CDV3 Gene

  • GC03P134776
  • GC03P133292
  • GC03P130671

Summaries for CDV3 Gene

GeneCards Summary for CDV3 Gene

CDV3 (CDV3 Homolog) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDV3 Gene

Genomics for CDV3 Gene

Regulatory Elements for CDV3 Gene

Enhancers for CDV3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CDV3 on UCSC Golden Path with GeneCards custom track

Promoters for CDV3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CDV3 on UCSC Golden Path with GeneCards custom track

Genomic Location for CDV3 Gene

Chromosome:
3
Start:
133,573,590 bp from pter
End:
133,590,274 bp from pter
Size:
16,685 bases
Orientation:
Plus strand

Genomic View for CDV3 Gene

Genes around CDV3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CDV3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CDV3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDV3 Gene

Proteins for CDV3 Gene

  • Protein details for CDV3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UKY7-CDV3_HUMAN
    Recommended name:
    Protein CDV3 homolog
    Protein Accession:
    Q9UKY7
    Secondary Accessions:
    • B3KUC2
    • Q96IP9

    Protein attributes for CDV3 Gene

    Size:
    258 amino acids
    Molecular mass:
    27335 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CDV3 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CDV3 Gene

Proteomics data for CDV3 Gene at MOPED

Post-translational modifications for CDV3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CDV3 Gene

Domains & Families for CDV3 Gene

Protein Domains for CDV3 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CDV3 Gene

Graphical View of Domain Structure for InterPro Entry

Q9UKY7

UniProtKB/Swiss-Prot:

CDV3_HUMAN :
  • Belongs to the CDV3 family.
Family:
  • Belongs to the CDV3 family.
genes like me logo Genes that share domains with CDV3: view

No data available for Gene Families for CDV3 Gene

Function for CDV3 Gene

Phenotypes for CDV3 Gene

genes like me logo Genes that share phenotypes with CDV3: view

Animal Model Products

miRNA for CDV3 Gene

miRTarBase miRNAs that target CDV3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDV3 Gene

Localization for CDV3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CDV3 Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CDV3 Gene COMPARTMENTS Subcellular localization image for CDV3 gene
Compartment Confidence
nucleus 5
plasma membrane 5
cytosol 4

Gene Ontology (GO) - Cellular Components for CDV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with CDV3: view

Pathways & Interactions for CDV3 Gene

SuperPathways for CDV3 Gene

No Data Available

Interacting Proteins for CDV3 Gene

Gene Ontology (GO) - Biological Process for CDV3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CDV3 Gene

Drugs & Compounds for CDV3 Gene

No Compound Related Data Available

Transcripts for CDV3 Gene

Unigene Clusters for CDV3 Gene

CDV3 homolog (mouse):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CDV3 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8
SP1: - - - -
SP2: - -
SP3:
SP4: - - -
SP5:

Relevant External Links for CDV3 Gene

GeneLoc Exon Structure for
CDV3
ECgene alternative splicing isoforms for
CDV3

Expression for CDV3 Gene

mRNA expression in normal human tissues for CDV3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CDV3 Gene

This gene is overexpressed in Muscle - Skeletal (x4.2).

Protein differential expression in normal tissues from HIPED for CDV3 Gene

This gene is overexpressed in Urine (11.6) and Bone marrow stromal cell (11.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for CDV3 Gene



SOURCE GeneReport for Unigene cluster for CDV3 Gene Hs.518265

mRNA Expression by UniProt/SwissProt for CDV3 Gene

Q9UKY7-CDV3_HUMAN
Tissue specificity: Expression levels correlate with those of HER-2/neu in breast cancer cells.
genes like me logo Genes that share expression patterns with CDV3: view

Protein tissue co-expression partners for CDV3 Gene

- Elite partner

Primer Products

In Situ Assay Products

Orthologs for CDV3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CDV3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CDV3 35
  • 90.83 (n)
  • 91.47 (a)
-- 36
  • 91 (a)
OneToMany
-- 36
  • 74 (a)
OneToMany
dog
(Canis familiaris)
Mammalia CDV3 35
  • 95.1 (n)
  • 96.61 (a)
CDV3 36
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia LOC102639170 35
  • 88.95 (n)
  • 90.06 (a)
Gm7236 16
Cdv3 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CDV3 35
  • 99.87 (n)
  • 99.61 (a)
CDV3 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cdv3 35
  • 81.88 (n)
  • 80.1 (a)
oppossum
(Monodelphis domestica)
Mammalia CDV3 36
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia CDV3 36
  • 85 (a)
OneToOne
chicken
(Gallus gallus)
Aves CDV3 35
  • 69.65 (n)
  • 63.68 (a)
CDV3 36
  • 74 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CDV3 36
  • 58 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cdv3 35
  • 62.57 (n)
  • 56.15 (a)
African clawed frog
(Xenopus laevis)
Amphibia cdv3-prov 35
zebrafish
(Danio rerio)
Actinopterygii cdv3 35
  • 60 (n)
  • 56.36 (a)
wufa12e09 35
cdv3 36
  • 50 (a)
OneToOne
Species with no ortholog for CDV3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CDV3 Gene

ENSEMBL:
Gene Tree for CDV3 (if available)
TreeFam:
Gene Tree for CDV3 (if available)

Paralogs for CDV3 Gene

Pseudogenes.org Pseudogenes for CDV3 Gene

genes like me logo Genes that share paralogs with CDV3: view

No data available for Paralogs for CDV3 Gene

Variants for CDV3 Gene

Sequence variations from dbSNP and Humsavar for CDV3 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1073196 -- 133,578,962(-) AAATA(C/T)TCTCT intron-variant
rs1992634 -- 133,576,979(-) tccca(A/G)ctact intron-variant
rs1992637 -- 133,576,917(-) tgagc(C/T)gagat intron-variant
rs7433905 -- 133,582,925(+) CAAAA(A/G)ATAAA intron-variant
rs9820344 -- 133,584,828(+) agact(A/G)gaatg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CDV3 Gene

Variant ID Type Subtype PubMed ID
esv27719 CNV Loss 19812545
esv2674678 CNV Deletion 23128226

Variation tolerance for CDV3 Gene

Residual Variation Intolerance Score: 66.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.46; 43.20% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CDV3 Gene

HapMap Linkage Disequilibrium report
CDV3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDV3 Gene

Disorders for CDV3 Gene

Relevant External Links for CDV3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CDV3

No disorders were found for CDV3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDV3 Gene

Publications for CDV3 Gene

  1. Identification of differentially expressed genes associated with HER- 2/neu overexpression in human breast cancer cells. (PMID: 10497265) Oh J.J. … Slamon D.J. (Nucleic Acids Res. 1999) 2 3 4 67
  2. Novel mRNA molecules are induced in hypertrophied ventricles of carnitine-deficient mice and belong to a family of up-regulated gene in cells overexpressing c-erbB-2. (PMID: 12359334) Fukumaru S. … Saheki T. (Biochim. Biophys. Acta 2002) 3 23
  3. Analysis of HIV-1 Gag protein interactions via biotin ligase tagging. (PMID: 25631074) Ritchie C. … Barklis E. (J. Virol. 2015) 3
  4. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  5. Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. (PMID: 24999758) Elzi D.J. … Shiio Y. (J. Proteome Res. 2014) 3

Products for CDV3 Gene

Sources for CDV3 Gene

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