CDV3 Gene
protein-coding GIFtS: 45
GCID: GC03P133292
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|
CDV3 homolog (mouse)
| |
Aliases
for CDV3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CDV3 Homolog (Mouse)1 2 | | H411 2 3 | | Carnitine Deficiency-Associated Gene Expressed In Ventricle 32 | | Protein CDV3 Homolog2 |
Export aliases for CDV3 gene to outside databasesPrevious GC identifers: GC03P134776 GC03P130671 |
Summaries
for CDV3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CDV3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CDV3 gene promoter:
N-Myc GCNF POU3F1 GCNF-2 GATA-1 GATA-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDV3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDV3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q22.1 Ensembl cytogenetic band: 3q22.1 HGNC cytogenetic band: 3q22.1CDV3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P133292: view genomic region
(about GC identifiers)
Start:
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133,292,434 bp from pter |
End:
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133,309,118 bp from pter |
Size:
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16,685 bases |
Orientation:
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plus strand |
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Proteins
for CDV3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CDV3_HUMAN, Q9UKY7 (See
protein sequence)Recommended Name: Protein CDV3 homolog Size: 258 amino acids; 27335 Da
Subcellular location: Cytoplasm (By similarity)
Secondary accessions: B3KUC2 Q96IP9Alternative splicing: 3 isoforms: Q9UKY7-1 Q9UKY7-2 Q9UKY7-3 Explore the universe of human proteins at neXtProt for CDV3: NX_Q9UKY7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UKY7
CDV3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001127894.1 NP_001127895.1 NP_060018.1
ENSEMBL proteins: ENSP00000264993 ENSP00000391955 ENSP00000421340 ENSP00000422866 ENSP00000413272 ENSP00000423349 ENSP00000424742 ENSP00000425297 ENSP00000421495
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CDV3 for ontologies About GeneDecksing
CDV3 Antibody Products:
Assay Products for CDV3: |
Protein
Domains /
Families
for CDV3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDV3 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9UKY7ProtoNet protein and cluster: Q9UKY7 UniProtKB/Swiss-Prot: CDV3_HUMAN, Q9UKY7Similarity: Belongs to the CDV3 family |
Function
for CDV3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDV3 (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDV3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CDV3 (NM_017548) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDV3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDV3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDV3 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
CDV3 for ontologies About GeneDecksing
|
Pathways & Interactions
for CDV3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDV3
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
3 Interacting proteins for CDV3 (Q9UKY73 ENSP000002649934) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table
CDV3 for ontologies About GeneDecksing
|
Drugs & Compounds
for CDV3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CDV3
Search CenterWatch for drugs/clinical trials and news about CDV3
|
Transcripts
for CDV3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDV3 gene (3 alternative transcripts): NM_001134422.1 NM_001134423.1 NM_017548.4 Unigene Cluster for CDV3: CDV3 homolog (mouse) Hs.518265 [show with all ESTs]Unigene Representative Sequence: NM_0011344229 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000264993(uc003epq.3) ENST00000431519 ENST00000503932 ENST00000508481
ENST00000420115(uc003epp.4 uc003epr.3) ENST00000504867 ENST00000507408
ENST00000511392 ENST00000515421
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDV3 (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDV3 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): CDV3 (NM_017548) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDV3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDV3 |
Additional cDNA sequence: AF103803.1 AK025647.1 AK026272.1 AK096865.1 BC007338.2 BC034727.1 23 DOTS entries: DT.219619 DT.101986395 DT.100803619 DT.100885941 DT.95254752 DT.92035078 DT.120915143 DT.120915174 DT.100885934 DT.97865115 DT.100728254 DT.120915197 DT.91768457 DT.100885936 DT.101963296 DT.120668042 DT.100885933 DT.100885938 DT.120915151 DT.91768441 DT.91886643 DT.95338144 DT.75104934 24/459 AceView cDNA sequences (see all 459): CB135107 BC007338 CB135397 AI928407 AA865615 CD515674 R81810 AI480155 R98175 CF128116 CD628308 BF446653 AI253069 BE550139 BQ671008 BM783568 BI714812 AI540402 AI983660 BU175849 BU685720 CD365007 AA557238 AI399724
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for CDV3 About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 |
|---|
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| SP1: | | | - | | - | | - | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | - | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CDV3
|
Expression
for CDV3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CDV3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTTGGCAGT
About this image
See CDV3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDV3
SOURCE GeneReport for Unigene cluster: Hs.518265
UniProtKB/Swiss-Prot: CDV3_HUMAN, Q9UKY7Tissue specificity: Expression levels correlate with those of HER-2/neu in breast cancer cells
SABiosciences Custom PCR Arrays for CDV3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDV3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CDV3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDV3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDV3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDV3 |
Orthologs
for CDV3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CDV3 gene from 6/17 species (see all 17) About this table
ENSEMBL Gene Tree for CDV3 (if available)
TreeFam Gene Tree for CDV3 (if available) |
Paralogs
for CDV3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CDV3 gene
CDV3 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CDV3
PGOHUM00000238102
|
Genomic Variants
for CDV3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDV3 (133292434 - 133309118 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for CDV3
1 Indel: 68468 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDV3 |
|
Disorders
/ Diseases
for CDV3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CDV3 for disorders About GeneDecksing
3  diseases for CDV3: About MalaCardscarnitine deficiency female breast cancer breast cancer
Export disorders for CDV3 gene to outside databases
|
Publications
for CDV3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDV3 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with CDV3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of differentially expressed genes associated with HER- 2/neu overexpression in human breast cancer cells. (PubMed id 10497265)1, 2, 3 Oh J.J.... Slamon D.J. (1999)
- Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Novel mRNA molecules are induced in hypertrophied ventricles of carnitine-deficient mice and belong to a family of up-regulated gene in cells overexpressing c-erbB-2. (PubMed id 12359334)1, 9 Fukumaru S....Saheki T. (2002)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
|
External Searches for CDV3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CDV3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CDV3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CDV3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CDV3 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for CDV3 gene:
Search GeneIP for patents involving CDV3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CDV3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CDV3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDV3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDV3 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDV3 | | OriGene 3'-UTR Clone for CDV3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDV3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDV3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CDV3 | | OriGene Custom Protein Services for CDV3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDV3 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDV3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDV3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDV3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDV3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDV3 |
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 |  |  |  | |
| | | | Search Tocris compounds for CDV3 |
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 | | | CDV3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDV3 |
|  |  |  | | | | ThermoFisher Antibodies for CDV3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDV3 |
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