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Aliases for CDRT15L2 Gene

Aliases for CDRT15L2 Gene

  • CMT1A Duplicated Region Transcript 15-Like 2 2 3 5

External Ids for CDRT15L2 Gene

Previous GeneCards Identifiers for CDRT15L2 Gene

  • GC17P020424
  • GC17P020481
  • GC17P019685
  • GC17P020485
  • GC17P020726
  • GC17P021208
  • GC17P021467
  • GC17P021896
  • GC17P020944
  • GC17P021682

Summaries for CDRT15L2 Gene

GeneCards Summary for CDRT15L2 Gene

CDRT15L2 (CMT1A Duplicated Region Transcript 15-Like 2) is a Protein Coding gene. An important paralog of this gene is CDRT15.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDRT15L2 Gene

Genomics for CDRT15L2 Gene

Regulatory Elements for CDRT15L2 Gene


Genomic Location for CDRT15L2 Gene

Chromosome:
17
Start:
20,579,724 bp from pter
End:
20,580,911 bp from pter
Size:
1,188 bases
Orientation:
Plus strand

Genomic View for CDRT15L2 Gene

Genes around CDRT15L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CDRT15L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CDRT15L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDRT15L2 Gene

Proteins for CDRT15L2 Gene

  • Protein details for CDRT15L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MXV6-CD15L_HUMAN
    Recommended name:
    CMT1A duplicated region transcript 15 protein-like protein
    Protein Accession:
    A8MXV6

    Protein attributes for CDRT15L2 Gene

    Size:
    281 amino acids
    Molecular mass:
    30100 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CDRT15L2 Gene

Proteomics data for CDRT15L2 Gene at MOPED

Post-translational modifications for CDRT15L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CDRT15L2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CDRT15L2 Gene

Domains & Families for CDRT15L2 Gene

Protein Domains for CDRT15L2 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CDRT15L2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CDRT15L2: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CDRT15L2 Gene

Function for CDRT15L2 Gene

Phenotypes for CDRT15L2 Gene

GenomeRNAi human phenotypes for CDRT15L2:
genes like me logo Genes that share phenotypes with CDRT15L2: view

Animal Model Products

CRISPR Products

miRNA for CDRT15L2 Gene

miRTarBase miRNAs that target CDRT15L2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDRT15L2 Gene

Localization for CDRT15L2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CDRT15L2 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CDRT15L2 Gene COMPARTMENTS Subcellular localization image for CDRT15L2 gene
Compartment Confidence
mitochondrion 2
cytosol 1
endoplasmic reticulum 1
nucleus 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for CDRT15L2 Gene

Pathways & Interactions for CDRT15L2 Gene

SuperPathways for CDRT15L2 Gene

No Data Available

Interacting Proteins for CDRT15L2 Gene

Gene Ontology (GO) - Biological Process for CDRT15L2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CDRT15L2 Gene

Drugs & Compounds for CDRT15L2 Gene

No Compound Related Data Available

Transcripts for CDRT15L2 Gene

mRNA/cDNA for CDRT15L2 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CDRT15L2 Gene

CMT1A duplicated region transcript 15-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CDRT15L2 Gene

No ASD Table

Relevant External Links for CDRT15L2 Gene

GeneLoc Exon Structure for
CDRT15L2
ECgene alternative splicing isoforms for
CDRT15L2

Expression for CDRT15L2 Gene

mRNA expression in normal human tissues for CDRT15L2 Gene

mRNA differential expression in normal tissues according to GTEx for CDRT15L2 Gene

This gene is overexpressed in Testis (x43.7) and Brain - Hippocampus (x7.5).

Protein differential expression in normal tissues from HIPED for CDRT15L2 Gene

This gene is overexpressed in Islet of Langerhans (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CDRT15L2 Gene



SOURCE GeneReport for Unigene cluster for CDRT15L2 Gene Hs.131916

genes like me logo Genes that share expression patterns with CDRT15L2: view

Protein tissue co-expression partners for CDRT15L2 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CDRT15L2 Gene

Orthologs for CDRT15L2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CDRT15L2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC455056 35
  • 97.51 (n)
  • 95.02 (a)
-- 36
  • 94 (a)
OneToMany
-- 36
  • 94 (a)
OneToMany
Species with no ortholog for CDRT15L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CDRT15L2 Gene

ENSEMBL:
Gene Tree for CDRT15L2 (if available)
TreeFam:
Gene Tree for CDRT15L2 (if available)

Paralogs for CDRT15L2 Gene

Paralogs for CDRT15L2 Gene

genes like me logo Genes that share paralogs with CDRT15L2: view

Variants for CDRT15L2 Gene

Structural Variations from Database of Genomic Variants (DGV) for CDRT15L2 Gene

Variant ID Type Subtype PubMed ID
nsv520772 CNV Loss 19592680
nsv521025 CNV Gain 19592680
dgv936e1 CNV Complex 17122850
nsv833399 CNV Loss 17160897
esv23447 CNV Gain+Loss 19812545
dgv3102n71 CNV Loss 21882294
nsv907875 CNV Gain 21882294
esv2715742 CNV Deletion 23290073
dgv3103n71 CNV Gain+Loss 21882294
dgv3104n71 CNV Loss 21882294
dgv3105n71 CNV Gain 21882294
essv13903 CNV CNV 17122850
nsv510703 CNV Loss 20534489
esv2751619 CNV Gain 17911159
nsv457705 CNV Loss 19166990

Variation tolerance for CDRT15L2 Gene

Gene Damage Index Score: 1.21; 24.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CDRT15L2 Gene

HapMap Linkage Disequilibrium report
CDRT15L2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for CDRT15L2 Gene

Disorders for CDRT15L2 Gene

Relevant External Links for CDRT15L2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CDRT15L2

No disorders were found for CDRT15L2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDRT15L2 Gene

Publications for CDRT15L2 Gene

  1. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3

Products for CDRT15L2 Gene

Sources for CDRT15L2 Gene

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