Aliases for CDRT1 Gene
External Ids for CDRT1 Gene
Previous HGNC Symbols for CDRT1 Gene
Previous GeneCards Identifiers for CDRT1 Gene
Members of the F-box protein family, such as FBXW10, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
GeneCards Summary for CDRT1 Gene
CDRT1 (CMT1A Duplicated Region Transcript 1) is a Protein Coding gene. Diseases associated with CDRT1 include Hereditary Neuropathies and Charcot-Marie-Tooth Disease. An important paralog of this gene is FBXW10.