CDPF1 Gene
protein-coding GIFtS: 33
GCID: GC22M046641
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cysteine-rich, DPF motif domain containing 1(Previous name: chromosome 22 open reading frame 40 )
(Previous symbol: C22orf40)
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Aliases
for CDPF1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cysteine-Rich, DPF Motif Domain Containing 11 2 | | C22orf401 2 3 | | LOC1503831 | | Chromosome 22 Open Reading Frame 401 | | Cysteine-Rich DPF Motif Domain-Containing Protein 12 | | UPF0595 Protein C22orf402 |
Export aliases for CDPF1 gene to outside databases |
Summaries
for CDPF1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CDPF1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for CDPF1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDPF1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDPF1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q13.31 Ensembl cytogenetic band: 22q13.31 HGNC cytogenetic band: 22q13.31CDPF1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M046641: view genomic region
(about GC identifiers)
Start:
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46,639,908 bp from pter |
End:
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46,646,576 bp from pter |
Size:
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6,669 bases |
Orientation:
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minus strand |
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Proteins
for CDPF1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CDPF1_HUMAN, Q6NVV7 (See
protein sequence)Recommended Name: Cysteine-rich DPF motif domain-containing protein 1 Size: 123 amino acids; 13877 Da
Secondary accessions: A6NCA1 A9IU12 A9IU16 Q3ZCR8Explore the universe of human proteins at neXtProt for CDPF1: NX_Q6NVV7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6NVV7
CDPF1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_997210.3
ENSEMBL proteins: ENSP00000384451 ENSP00000325301 ENSP00000370425 ENSP00000385460
Human Recombinant Protein Products for CDPF1:
CDPF1 Antibody Products:
Assay Products for CDPF1: |
Protein
Domains /
Families
for CDPF1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDPF1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q6NVV7ProtoNet protein and cluster: Q6NVV7 UniProtKB/Swiss-Prot: CDPF1_HUMAN, Q6NVV7Similarity: Belongs to the CDPF1 family |
Function
for CDPF1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDPF1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDPF1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for CDPF1 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDPF1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDPF1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDPF1 |
|
Pathways & Interactions
for CDPF1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDPF1
|
Drugs & Compounds
for CDPF1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CDPF1
Search CenterWatch for drugs/clinical trials and news about CDPF1
|
Transcripts
for CDPF1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDPF1 gene (2 alternative transcripts): NM_001008917.1 NM_207327.4 Unigene Cluster for CDPF1: Cysteine-rich, DPF motif domain containing 1 Hs.592209 [show with all ESTs]Unigene Representative Sequence: BC0364626 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000404583 ENST00000314567(uc003bhe.3) ENST00000381037(uc003bhf.3)
ENST00000404744 ENST00000475605 ENST00000474256
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDPF1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDPF1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for CDPF1 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDPF1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDPF1 |
Additional cDNA sequence: BC036462.1 BC045796.2 BC067871.1 BX648331.1 CR456415.1 10 DOTS entries: DT.95174986 DT.407609 DT.101983439 DT.95266789 DT.95266790 DT.100779758 DT.100777940 DT.441884 DT.86855091 DT.95223788 24/131 AceView cDNA sequences (see all 131): BU554090 CR617183 BX340707 BU553442 NM_207327 BC067871 BU552823 H55183 CR456415 BU848762 BX394144 BU845440 BU849557 BM709351 AI141192 CR600118 AV645614 N66686 BE501980 CR621136 CR617709 CR598840 CR613320 BE550218
GeneLoc Exon Structure
|
Expression
for CDPF1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
See CDPF1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDPF1
SOURCE GeneReport for Unigene cluster: Hs.592209
SABiosciences Custom PCR Arrays for CDPF1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDPF1
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat CDPF1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDPF1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDPF1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDPF1 |
Orthologs
for CDPF1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CDPF1 gene from 6/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Cdpf11 , 5 |
RIKEN cDNA 2210021J22 gene5
cysteine rich, DPF motif domain containing 11 |
78.15(n)1
75.63(a)1 |
|
15 (40.42 cM)5
723551 NM_001164625.11 NP_001158097.11
858069725 |
chicken
(Gallus gallus) |
Aves |
CDPF11 |
cysteine-rich, DPF motif domain containing 1 |
66.94(n)
66.67(a) |
|
418246 NM_001030772.1 NP_001025943.1 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.15822 |
Xenopus laevis transcribed sequence with weak similarity more |
71.69(n) |
|
AW641442.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
BM026756.12 |
-- |
73.65(n) |
|
BM026756.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG117556 |
-- |
24(a) |
1 ↔ 1 |
3R(4503865-4504677) |
worm
(Caenorhabditis elegans) |
Secernentea |
D2089.36 |
Protein D2089.3 |
13(a) |
1 ↔ 1 |
II(10661538-10665031) |
ENSEMBL Gene Tree for CDPF1 (if available)
TreeFam Gene Tree for CDPF1 (if available) |
Paralogs
for CDPF1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CDPF1 gene
CDPF1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CDPF1
PGOHUM00000259779
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Genomic Variants
for CDPF1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDPF1 (46639908 - 46646576 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CDPF1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDPF1 |
|
Disorders
/ Diseases
for CDPF1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CDPF1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDPF1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CDPF1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1 Collins J.E.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)2 Dunham I....O'Brien K.P. (1999)
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External Searches for CDPF1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing CDPF1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CDPF1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CDPF1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CDPF1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CDPF1 gene:
Search GeneIP for patents involving CDPF1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CDPF1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CDPF1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDPF1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDPF1 | | | OriGene Protein Over-expression Lysate for CDPF1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDPF1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDPF1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDPF1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CDPF1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CDPF1 | | OriGene Custom Protein Services for CDPF1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDPF1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDPF1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDPF1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDPF1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDPF1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDPF1 |
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 |  |  |  | |
| | | | Search Tocris compounds for CDPF1 |
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 | | | CDPF1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDPF1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for CDPF1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDPF1 |
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