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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDNF Gene

protein-coding   GIFtS: 49
GCID: GC10M014771

Cerebral Dopamine Neurotrophic Factor

(Previous names: arginine-rich, mutated in early stage tumors-like 1)
(Previous symbol: ARMETL1)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cerebral Dopamine Neurotrophic Factor1 2
ARMETL11 2 3
Conserved Dopamine Neurotrophic Factor1 2 3
Arginine-Rich, Mutated In Early Stage Tumors-Like 11 2
ARMET-Like Protein 12 3

External Ids:    HGNC: 249131   Entrez Gene: 4415492   Ensembl: ENSG000001852677   OMIM: 6112335   UniProtKB: Q49AH03   

Export aliases for CDNF gene to outside databases

Previous GC identifers: GC10M014902 GC10M014861


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CDNF Gene: 
CDNF (cerebral dopamine neurotrophic factor) is a protein-coding gene. Diseases associated with CDNF include cocaine dependence, and cerebritis. GO annotations related to this gene include growth factor activity. An important paralog of this gene is MANF.

UniProtKB/Swiss-Prot: CDNF_HUMAN, Q49AH0
Function: Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of
dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents
the degeneration of dopaminergic neurons in substantia nigra (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.2  NT_008705.16  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for CDNF
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): CDNF promoter sequence
   Search SABiosciences Chromatin IP Primers for CDNF

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDNF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p13   Ensembl cytogenetic band:  10p13   HGNC cytogenetic band: 10p13

CDNF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDNF gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M014771:  view genomic region     (about GC identifiers)

Start:
14,861,249 bp from pter      End:
14,880,574 bp from pter
Size:
19,326 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CDNF_HUMAN, Q49AH0 (See protein sequence)
Recommended Name: Cerebral dopamine neurotrophic factor precursor  
Size: 187 amino acids; 20964 Da
Subcellular location: Secreted
2 PDB 3D structures from and Proteopedia for CDNF:
2LPN (3D)        2W50 (3D)    
Secondary accessions: A2RUU0 B4DVW3
Alternative splicing: 2 isoforms:  Q49AH0-1   Q49AH0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CDNF: NX_Q49AH0

Explore proteomics data for CDNF at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q49AH0

  • CDNF Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CDNF Protein Expression
    REFSEQ proteins: NP_001025125.2  
    ENSEMBL proteins: 
     ENSP00000367703   ENSP00000419395  

    Human Recombinant Protein Products for CDNF: 
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    OriGene Protein Over-expression Lysate for CDNF
    OriGene MassSpec for CDNF 
    OriGene Custom Protein Services for CDNF
    GenScript Custom Purified and Recombinant Proteins Services for CDNF
    Novus Biologicals CDNF Proteins
    Novus Biologicals CDNF Lysate
    Sino Biological Recombinant Protein for CDNF
    Sino Biological Cell Lysate for CDNF 
    ProSpec Recombinant Protein for CDNF
    Cloud-Clone Corp. Proteins for CDNF 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    CDNF for ontologies           About GeneDecksing



    CDNF Antibody Products: 
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    Novus Biologicals CDNF Antibodies
    Abcam antibodies for CDNF
    Cloud-Clone Corp. Antibodies for CDNF 
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    LSBio Antibodies in human, mouse, rat for CDNF 

    Assay Products for CDNF: 
    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CDNF 
    Cloud-Clone Corp. CLIAs for CDNF


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR019345 Armet_prot

    Graphical View of Domain Structure for InterPro Entry Q49AH0

    ProtoNet protein and cluster: Q49AH0

    UniProtKB/Swiss-Prot: CDNF_HUMAN, Q49AH0
    Similarity: Belongs to the ARMET family


    CDNF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CDNF_HUMAN, Q49AH0
    Function: Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of
    dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents
    the degeneration of dopaminergic neurons in substantia nigra (By similarity)
    Induction: Not induced by endoplasmic reticulum stress

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008083growth factor activity IEA--
         
    CDNF for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for CDNF:
     G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CDNF 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CDNF

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CDNF 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CDNF 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidCDNF 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for CDNF
    Sirion Biotech Customized adenovirus for overexpression of CDNF

    Clone
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    OriGene ORF clones in mouse, rat for CDNF
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    Sino Biological Human cDNA Clone for CDNF
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDNF
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                         Customized lentivirus expression plasmids for stable overexpression of CDNF 

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    Search LifeMap BioReagents cell lines for CDNF
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDNF


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDNF

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CDNF

    Search CenterWatch for drugs/clinical trials and news about CDNF

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CDNF gene: 
    NM_001029954.2  

    Unigene Cluster for CDNF:

    Cerebral dopamine neurotrophic factor
    Hs.559067  [show with all ESTs]
    Unigene Representative Sequence: BC037872
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000378442(uc001inb.1 uc010qbv.1 uc001inc.1) ENST00000378441
    ENST00000467405 ENST00000466269 ENST00000465530

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CDNF
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CDNF
    SwitchGear 3'UTR luciferase reporter plasmidCDNF 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CDNF
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDNF
    Clone
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    OriGene ORF clones in mouse, rat for CDNF
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    GenScript: all cDNA clones in your preferred vector: CDNF (NM_001029954)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CDNF
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDNF
    Sirion Biotech Customized lentivirus for stable overexpression of CDNF 
                         Customized lentivirus expression plasmids for stable overexpression of CDNF 
    Primer
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    OriGene qPCR primer pairs and template standards for CDNF
    OriGene qSTAR qPCR primer pairs in human, mouse for CDNF
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDNF
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDNF

    Additional mRNA sequence: 

    AK131035.1 BC037872.1 BC133042.1 BC133044.1 BC144619.1 

    5 DOTS entries:

    DT.435105  DT.95320632  DT.121272798  DT.95262524  DT.86848108 

    24/25 AceView cDNA sequences (see all 25):

    AA018896 BI964826 F31353 CK903443 AI810745 BC037872 BI963176 AA885943 
    AK131035 BG742772 AW450272 AI807908 BQ025443 AI214900 BG213461 AA019552 
    BI464979 BM984171 BG742840 T68138 AV657190 AA018863 BQ321568 AA019437 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CDNF    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b
    SP1:        -     -     -     -                                             
    SP2:                          -           -                 -               
    SP3:                          -     -     -                                 
    SP4:                                -     -                                 


    ECgene alternative splicing isoforms for CDNF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDNF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTTTGTGT
    CDNF Expression
    About this image


    See CDNF Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDNF

    SOURCE GeneReport for Unigene cluster: Hs.559067

    UniProtKB/Swiss-Prot: CDNF_HUMAN, Q49AH0
    Tissue specificity: Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the
    optic nerve and corpus callosum

        SABiosciences Custom PCR Arrays for CDNF
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDNF

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CDNF gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdnf1 , 5 cerebral dopamine neurotrophic factor1, 5 82.89(n)1
    77.54(a)1
      2 (1.99 cM)5
    2275261  NM_177647.41  NP_808315.11 
     35130305 
    lizard
    (Anolis carolinensis)
    Reptilia CDNF6
    cerebral dopamine neurotrophic factor
    58(a)
    1 ↔ 1
    GL343559.1(219974-231276)
    zebrafish
    (Danio rerio)
    Actinopterygii cdnf6
    cerebral dopamine neurotrophic factor
    45(a)
    1 ↔ 1
    4(8650204-8654638)
    fruit fly
    (Drosophila melanogaster)
    Insecta Manf6
    Mesencephalic astrocyte-derived neurotrophic facto...
    44(a)
    1 → many
    3R(12175126-12176523)
    worm
    (Caenorhabditis elegans)
    Secernentea Y54G2A.236
    MANF/CDNF-like protein
    45(a)
    1 → many
    IV(2927515-2928423)


    ENSEMBL Gene Tree for CDNF (if available)
    TreeFam Gene Tree for CDNF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CDNF gene
    MANF2  
    1 SIMAP similar gene for CDNF using alignment to 1 protein entry:     CDNF_HUMAN:
    MANF

    CDNF for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/418 SNPs in CDNF are shown (see all 418)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs750767401,2
    C,F--14860794(+) GGAGAC/TGGAAC 1 -- ds50012Minor allele frequency- T:0.23WA 120
    rs1913173651,2
    --14860797(+) GACGGA/TACCTC 1 -- ds50010--------
    rs561155301,2
    C,F--14860800(+) GGAACC/GTCACT 1 -- ds50012Minor allele frequency- G:0.07WA NA 238
    rs1399344031,2
    --14860850(+) ATCCTC/TCCGCC 1 -- ds50010--------
    rs118190611,2
    C,F,H--14860853(+) ctcccG/Acctca 1 -- ds50013Minor allele frequency- A:0.05NA CSA WA 121
    rs118177211,2
    C,F,H--14860865(+) cctctT/Cgaagt 1 -- ds50013Minor allele frequency- C:0.08NA CSA WA 121
    rs1116686481,2
    C,F--14860888(+) GGTGTG/AAGCCA 1 -- ds50011Minor allele frequency- A:0.50NA 2
    rs618430071,2
    C,F--14860952(+) ATAATG/TTTTCT 1 -- ds50011Minor allele frequency- T:0.00NA 2
    rs1869662841,2
    --14860983(+) TATGTA/TCATAC 1 -- ds50010--------
    rs118173271,2
    C,F,A,H--14861012(+) taattA/Ttccta 1 -- ds50017Minor allele frequency- T:0.03NS EA NA CSA WA 522

    HapMap Linkage Disequilibrium report for CDNF (14861249 - 14880574 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CDNF:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv5899CNV Insertion18451855
    nsv471664CNV Gain+Loss15918152

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CDNF
    DNA2.0 Custom Variant and Variant Library Synthesis for CDNF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611233    OMIM disorders: --

    5 diseases for CDNF:    About MalaCards
    cocaine dependence    cerebritis    parkinson's disease    hepatocellular carcinoma
    neuronitis

    1 disease from the University of Copenhagen DISEASES database for CDNF:
    Parkinson's disease

    CDNF for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Human Genome Epidemiology (HuGE) Navigator: CDNF (2 documents)

    Export disorders for CDNF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDNF gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with CDNF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo. (PubMed id 17611540)1, 2, 3 Lindholm P.... Saarma M. (2007)
    2. The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional. (PubMed id 19258449)1, 2 Parkash V.... Goldman A. (2009)
    3. Analysis of mutations and the association between pol ymorphisms in the cerebral dopamine neurotrophic factor (CDNF) gene and Parkins on disease. (PubMed id 21320571)1 Choi J.M....Kim Y.J. (2011)
    4. Association analysis between polymorphisms in the conserved dopamine neurotrophic factor (CDNF) gene and cocaine dependence. (PubMed id 19429035)1 Lohoff F.W....Oslin D.W. (2009)
    5. Armet, a UPR-upregulated protein, inhibits cell proliferation and ER stress-induced cell death. (PubMed id 18561914)2 Apostolou A....Fang S. (2008)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    8. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1 Brandenberger R.... Stanton L.W. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Insight into hepatocellular carcinogenesis at transcriptome level by comparing gene expression profiles of hepatocellular carcinoma with those of corresponding noncancerous liver. (PubMed id 11752456)1 Xu X.R.... Han Z.G. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 441549 HGNC: 24913 AceView: LOC441549 Ensembl:ENSG00000185267 euGenes: HUgn441549
    ECgene: CDNF H-InvDB: CDNF

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CDNF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CDNF gene:
    Search GeneIP for patents involving CDNF

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     EMD Millipore Custom Antibody & Bulk Services
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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