V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

CDKN2D Gene

protein-coding GIFtS: 63

GC19M010538

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
INK4D ^¹, ²
p19 ^¹, ²
p19-INK4D ^²
p19-INK4d ^³

Descriptions
CDK inhibitor p19INK4d ^²
cell cycle inhibitor, Nur77 associating protein ^²
cyclin-dependent kinase 4 inhibitor D p19 ^²
cyclin-dependent kinase inhibitor 2D ^²
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) ^²
inhibitor of cyclin-dependent kinase 4d ^²

External Ids
HGNC: 1790¹
Entrez Gene: 1032²
UniProtKB: P55273³
Ensembl: ENSG00000129355⁷

Search outside databases for aliases for CDKN2D gene

Previous GC identifers: GC19M010808 GC19M010899 GC19M010522

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for CDKN2D:

The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase

inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent

the activation of the CDK kinases, thus function as a cell growth regulator that controls cell

cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a

cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S

phase. The negative regulation of the cell cycle involved in this protein was shown to participate

in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced

variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq]

UniProtKB/Swiss-Prot: CDN2D_HUMAN, P55273

Function: Interacts strongly with CDK4 and CDK6 and inhibits them

Gene Wiki entry for CDKN2D

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the CDKN2D gene

Entrez Gene cytogenetic band: 19p13 Ensembl cytogenetic band: 19p13.2 HGNC cytogenetic band: 19p13

CDKN2D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M010538: (about GC identifiers)

Start:	10,538,138 bp from pter
End:	10,540,655 bp from pter
Size:	2,518 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000019.8 NT_011295.10

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: CDN2D_HUMAN, P55273 (See protein sequence)

Recommended Name: Cyclin-dependent kinase 4 inhibitor D

Size: 166 amino acids; 17700 Da

PDB structure from and Proteopedia :

1BD8 (3D)

1BI8 (3D)

Secondary accessions: Q13102 Q6FGE9

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001791.1 NP_524145.1

ENSEMBL proteins:

ENSP00000337056 ENSP00000377224

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (p19 INK4d)
	Human Recombinant Proteins from Abnova (CDKN2D)

OriGene Purified Recombinant Human Proteins (see all 2): CDKN2D

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	8741839 15750620
GO:0005737	cytoplasm	IDA	15750620

About this table

Antibodies for CDKN2D:

	Invitrogen Antibodies for CDKN2D
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibody Arrays and Antibodies for CDKN2D
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (p19 INK4d), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (CDKN2D)
	Novus Biologicals Antibodies for CDKN2D

Assays for CDKN2D:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P55273

ProtoNet protein and cluster: P55273

UniProtKB/Swiss-Prot: CDN2D_HUMAN, P55273

Similarity: Belongs to the CDKN2 cyclin-dependent kinase inhibitor family

Similarity: Contains 4 ANK repeats

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CDKN2D)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CDKN2D)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_079421

Applied Biosystems Silencer® siRNAs for CDKN2D

Sigma-Aldrich siRNA and siRNA Panels for CDKN2D

Sigma-Aldrich shRNA Panels and shRNA for CDKN2D

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for CDKN2D
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001800
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001800
untagged cDNA clones in CMV expression vector (see all 2): NM_001800

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001800

UniProtKB/Swiss-Prot: CDN2D_HUMAN, P55273

Function: Interacts strongly with CDK4 and CDK6 and inhibits them

Genatlas biochemistry entry for CDKN2D:

cyclin dependent kinase 4 and 6 (CDK4/CDK6) inhibitor,p19,regulator of the cell cycle,passage

through the G1 checkpoint,expressed primarily in hematopoietic tissues

13 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Cdkn2d):

behavior/neurological	cellular	endocrine/exocrine gland	growth/size	hearing/vestibular/ear
homeostasis/metabolism	lethality-postnatal	muscle	nervous system	reproductive system
respiratory system	tumorigenesis	vision/eye

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004861	cyclin-dependent protein kinase inhibitor activity	IDA	8741839
GO:0019901	protein kinase binding	IPI	8741839

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

2 Sigma-Aldrich "Your Favorite Gene" Pathways for CDKN2D (Your Favorite Gene powered by Ingenuity)

Molecular Mechanisms of Cancer
Glioma Signaling

GeneDecks CDKN2D for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for CDKN2D

5/28 Interacting proteins for CDKN2D (P55273² ENSP00000337056³) via UniProtKB, MINT, and/or STRING (see all 28 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TBC1D17	Q9HA65²	MINT-67668
CDK6	ENSP00000265734³	STRING (score=.999)
CDK4	ENSP00000257904³	STRING (score=.998)
CCND1	ENSP00000227507³	STRING (score=.989)
CDKN2A	ENSP00000355153³	STRING (score=.986)

About this table

5/14 Gene Ontology (GO) biological process terms (links to tree view) (see all 14 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000079	regulation of cyclin-dependent protein kinase activity	IDA	8741839
GO:0000082	G1/S transition of mitotic cell cycle	IDA	10208428
GO:0000731	DNA synthesis during DNA repair	IMP	15750620
GO:0006916	anti-apoptosis	IMP	15750620
GO:0007050	cell cycle arrest	IDA	10208428

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for CDKN2D:

Inhibitor

Browse Tocris compounds for CDKN2D

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (CDKN2D)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (CDKN2D)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): NM_079421

Sigma-Aldrich siRNA and siRNA Panels for CDKN2D

Sigma-Aldrich shRNA Panels and shRNA for CDKN2D

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001800 NM_079421

REFSEQ mRNAs for CDKN2D gene (2 alternative transcripts):

NM_001800.3 NM_079421.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001800 NM_079421

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001800
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001800
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_001800

Additional cDNA sequence:

BC001822.2 CR542158.1 CR614055.1 U20498.1 U40343.1 U49399.1

2 DOTS entries:

DT.95103286 DT.100749508

24/126 AceView cDNA sequences (see all 126 ):

BC001822 BM272734 CA424868 CK824084 NM_079421 CR614055 BF902747 BF901939

BI028054 AA488276 BF902750 BU542469 BM142409 BE504281 BI031174 AI824257

BU689358 NM_001800 BF901942 AI383407 BQ881787 AI421483 BM894022 BI030509

highest scoring ESTs for CDKN2D:

BC001822 BE299378 BF203925 BG719545 BI462387 BI523657 BI669755 BI818887 BM505097 BM563048

Unigene Cluster for CDKN2D:

Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

Hs.435051 [show with all ESTs]

Unigene Representative Sequence: NM_001800

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000335766 ENST00000393599

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

CDKN2D expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for CDKN2D

¹ / ² / ³

3 probe-sets matching CDKN2D gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
1797_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U40343	0.80	1.00	0.91	1
210240_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	U20498	0.60	1.00	0.82	1
210240_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks CDKN2D for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATCAAAAAAA

SOURCE GeneReport for Unigene cluster: Hs.435051
Expression variation in blood from EXPOLDB for CDKN2D

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for CDKN2D gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	CDKN2D¹	--	cyclin-dependent kinase inhibitor 2D (p19, inhibits more	87.55(n) 89.76(a)	611216 XM_848853.1 XP_853946.1
chimpanzee (Pan troglodytes)	CDKN2D¹	--	cyclin-dependent kinase inhibitor 2D (p19, inhibits more	99.6(n) 100(a)	745942 XM_001165514.1 XP_001165514.1
cow (Bos taurus)	CDKN2D¹	--	cyclin-dependent kinase inhibitor 2D (p19, inhibits more	85.34(n) 87.95(a)	510244 NM_001046050.1 NP_001039515.1
mouse (Mus musculus)	Cdkn2d^{1, 5}	9⁵	cyclin-dependent kinase inhibitor 2D (p19, inhibits more^{1, 5}	81.73(n)¹ 86.75(a)¹	12581¹ NM_009878.2¹ NP_034008.2¹ AK132906⁵ AK140808⁵ (see all 10)

About this table Species with no ortholog for CDKN2D

ENSEMBL Gene Tree for CDKN2D

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for CDKN2D gene

CDKN2C² CDKN2B²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/18 NCBI SNPs in CDKN2D are shown (see all 18 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 34)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs17677316^1,2	C,F,H	10541241(+)	`AAAGGG/AAAACG`	2	--	ng3¹ trp³		12		NA EU EA WA	1048
	rs892082^1,2	A,F,H	10541478(-)	`AACTAT/CTGTCT`	2	--	ng3¹ tfbs³		4		EU EA WA	414
	rs4804509^1,2	C,F,H	10542641(+)	`GTGCAA/GATCAA`	1	--	ng3¹ tfbs³		4		EU EA WA	402
	rs3760648^1,2	C,F,H	10541103(-)	`GCCAAT/CGAATG`	2	--	ng3¹		4		EU EA WA	418
--	rs1465700^1,2	A	10541621(-)	`CTACTC/TGGGAG`	2	--	ng3¹		0	--	--	--	--
--	rs892081^1,2	A	10541684(-)	`GAAACA/CTCATA`	2	--	ng3¹		0	--	--	--	--
	rs1968445^1,2	C	10540240(-)	`CACCGC/GGAGCT`	2	R/R	syn¹ ese³		0	--	--	--	--
	rs1465701^1,2	A,C,F,H	10539842(-)	`CTTCTG/ATGGGG`	2	--	int¹		12		MN EU EA WA NS	1432
--	rs34511467^1,2	--	10541896(+)	`TTTTAC/GAGTGG`	2	--	ng3¹		0	--	--	--	--
--	rs892080^1,2	--	10541734(-)	`AAAGCA/CAAACA`	2	--	ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for CDKN2D (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600927

5 Novoseek disease relationships for CDKN2D gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
retinoblastoma	51.18	3	10962575 (1), 15172750 (1), 15738662 (1)
leukemia t-cell	39.60	1	15107822 (1)
cancer	25.83	4	10962575 (1), 18507837 (1)
osteosarcoma	23.58	2	9244358 (2)
tumors	18.39	5	9111168 (1), 11301189 (1), 15738662 (1), 9244358 (1)

About this table

Human Genome Epidemiology Navigator: CDKN2D (8 documents)
Tumor Gene Database: CDKN2D

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/62 PubMed articles for CDKN2D gene (see all 62 ):

Molecular cloning, expression pattern, and chromosomal localization of human CDKN2D/INK4d, an inhibitor of cyclin D-dependent kinases. (PubMed id 8575754)^{1, 2, 3, 4} Okuda T.... Downing J.R. (1995)
Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4. (PubMed id 8741839)^{1, 3, 4} Guan K.L.... Xiong Y. (1996)
Mutation testing in melanoma families: INK4A, CDK4 and INK4D. (PubMed id 10390011)^{1, 3, 4} Newton Bishop J.A....Bishop D.T. (1999)
Structure of human cyclin-dependent kinase inhibitor p19(INK4d): comparison to known ankyrin-repeat-containing structures and implications for the dysfunction of tumor suppressor p16(INK4a). (PubMed id 9782052)^{1, 3, 4} Baumgartner R....Holak T.A. (1998)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)^{3, 4} Gevaert K.... Vandekerckhove J. (2003)
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. (PubMed id 9751050)^{3, 4} Russo A.A.... Pavletich N.P. (1998)
Identification of human and mouse p19, a novel CDK4 and CDK6 inhibitor with homology to p16ink4. (PubMed id 7739548)^{3, 4} Chan F.K.M.... Winoto A. (1995)
Lack of p19INK4d in human testicular germ-cell tumours contrasts with high expression during normal spermatogenesis. (PubMed id 10962575)^{1, 3} Bartkova J....Bartek J. (2000)
Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter. (PubMed id 15107822)^{1, 3} Yokota T....Sakai T. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 1032	HGNC: 1790	AceView: CDKN2D	Ensembl:ENSG00000129355	euGenes: HUgn1032
ECgene: CDKN2D	H-InvDB: CDKN2D

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for CDKN2D	Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs	http://egp.gs.washington.edu/data/cdkn2d/

Licensable Technologies for CDKN2D
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for CDKN2D:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for CDKN2D-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for CDKN2D		Antibodies for CDKN2D
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for CDKN2D		Small molecules for CDKN2D
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (CDKN2D)
	Antibodies (CDKN2D)
	Chimera RNAi (CDKN2D)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (p19 INK4d)
	Antibodies (p19 INK4d)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for CDKN2D

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for CDKN2D

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
CDKN2D Gene at Home site.
Version 2.41.1
server5.xennexinc.com

CDKN2D Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for CDKN2D

Summaries
for CDKN2D

Genomic Location
for CDKN2D

Proteins
for CDKN2D

Protein Domains/
Families
for CDKN2D

Gene Function
for CDKN2D

Pathways & Interactions
for CDKN2D

Drugs & Compounds
for CDKN2D

Transcripts
for CDKN2D

Expression
for CDKN2D

Orthologs
for CDKN2D

Paralogs
for CDKN2D

SNPs/Variants
for CDKN2D

Disorders & Mutations
for CDKN2D

Medical News
for CDKN2D

Publications
for CDKN2D

Search for CDKN2D

Genome Databases showing CDKN2D

Other Databases showing CDKN2D

Specialized Databases showing CDKN2D

Licensable Technologies
for CDKN2D

Services
for CDKN2D

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

CDKN2D Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor CDKN2D

Summariesfor CDKN2D

Genomic Locationfor CDKN2D

Proteinsfor CDKN2D

Protein Domains/Familiesfor CDKN2D

Gene Functionfor CDKN2D

Pathways & Interactionsfor CDKN2D

Drugs & Compoundsfor CDKN2D

Transcriptsfor CDKN2D

Expression for CDKN2D

Orthologsfor CDKN2D

Paralogsfor CDKN2D

SNPs/Variantsfor CDKN2D

Disorders & Mutationsfor CDKN2D

Medical Newsfor CDKN2D

Publicationsfor CDKN2D

Search for CDKN2D

Genome Databases showing CDKN2D

Other Databases showing CDKN2D

Specialized Databases showing CDKN2D

Licensable Technologiesfor CDKN2D

Servicesfor CDKN2D

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for CDKN2D

Summaries
for CDKN2D

Genomic Location
for CDKN2D

Proteins
for CDKN2D

Protein Domains/
Families
for CDKN2D

Gene Function
for CDKN2D

Pathways & Interactions
for CDKN2D

Drugs & Compounds
for CDKN2D

Transcripts
for CDKN2D

Expression
for CDKN2D

Orthologs
for CDKN2D

Paralogs
for CDKN2D

SNPs/Variants
for CDKN2D

Disorders & Mutations
for CDKN2D

Medical News
for CDKN2D

Publications
for CDKN2D

Licensable Technologies
for CDKN2D

Services
for CDKN2D