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Aliases for CDKN2B-AS1 Gene

Subcategory (RNA class) for CDKN2B-AS1 Gene


Quality Score for this RNA gene is


Aliases for CDKN2B-AS1 Gene

  • CDKN2B Antisense RNA 1 2 3
  • CDKN2B Antisense RNA 1 (Non-Protein Coding) 2 3
  • Prostate Cancer Associated Transcript 12 2 3
  • P15 Antisense RNA 2 3
  • CDKN2BAS 3 6
  • ANRIL 3 6
  • CDKN2B Antisense RNA (Non-Protein Coding) 2
  • Antisense Noncoding RNA In The INK4 Locus 3
  • Antisense RNA In The INK4 Locus 2
  • Non-Protein Coding RNA 89 2
  • NCRNA00089 3
  • CDKN2B-AS 3
  • PCAT12 3
  • P15AS 3

External Ids for CDKN2B-AS1 Gene

ORGUL Members for CDKN2B-AS1 Gene

Summaries for CDKN2B-AS1 Gene

Entrez Gene Summary for CDKN2B-AS1 Gene

  • This gene is located within the CDKN2B-CDKN2A gene cluster at chromosome 9p21. The gene product is a functional RNA molecule that interacts with polycomb repressive complex-1 (PRC1) and -2 (PRC2), leading to epigenetic silencing of other genes in this cluster. This region is a significant genetic susceptibility locus for cardiovascular disease, and has also been linked to a number of other pathologies, including several cancers, intracranial aneurysm, type-2 diabetes, periodontitis, Alzheimer's disease, endometriosis, frailty in the elderly, and glaucoma. Multiple alternatively processed transcript variants have been detected, some of which may take the form of circular RNA molecules (PMID:21151960). [provided by RefSeq, May 2014]

GeneCards Summary for CDKN2B-AS1 Gene

CDKN2B-AS1 (CDKN2B Antisense RNA 1) is an RNA Gene, and is affiliated with the antisense RNA class. Diseases associated with CDKN2B-AS1 include endometriosis and intracranial aneurysm.

Gene Wiki entry for CDKN2B-AS1 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDKN2B-AS1 Gene

Genomics for CDKN2B-AS1 Gene

Genomic Location for CDKN2B-AS1 Gene

21,994,778 bp from pter
22,121,097 bp from pter
126,320 bases
Plus strand

Genomic View for CDKN2B-AS1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CDKN2B-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDKN2B-AS1 Gene

No data available for Regulatory Elements for CDKN2B-AS1 Gene

Proteins for CDKN2B-AS1 Gene

Post-translational modifications for CDKN2B-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CDKN2B-AS1 Gene

Domains for CDKN2B-AS1 Gene

Gene Families for CDKN2B-AS1 Gene

  • LNCRNA :Long non-coding RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CDKN2B-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for CDKN2B-AS1 Gene

Function for CDKN2B-AS1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CDKN2B-AS1 Gene

Localization for CDKN2B-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CDKN2B-AS1 Gene

Pathways for CDKN2B-AS1 Gene

SuperPathways for CDKN2B-AS1 Gene

No Data Available

Interacting Proteins for CDKN2B-AS1 Gene

Gene Ontology (GO) - Biological Process for CDKN2B-AS1 Gene


No data available for Pathways by source for CDKN2B-AS1 Gene

Compounds for CDKN2B-AS1 Gene

(1) PharmGKB related drug/compound annotations for CDKN2B-AS1 Gene

Drug/compound Annotation
"Antiinflammatory agents, non-steroids" CA
genes like me logo Genes that share compounds with CDKN2B-AS1: view

Transcripts for CDKN2B-AS1 Gene

mRNA/cDNA for CDKN2B-AS1 Gene

(18) Additional mRNA sequences :
(21) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CDKN2B-AS1 Gene

CDKN2B antisense RNA 1:
Representative Sequences:

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate CDKN2B-AS1
    • Block miRNA regulation of CDKN2B-AS1 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for CDKN2B-AS1

    Primer Products

    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for CDKN2B-AS1 Gene

    No ASD Table

    Relevant External Links for CDKN2B-AS1 Gene

    GeneLoc Exon Structure for
    ECgene alternative splicing isoforms for

    Expression for CDKN2B-AS1 Gene

    mRNA expression in normal human tissues for CDKN2B-AS1 Gene

    mRNA differential expression in normal tissues according to GTEx for CDKN2B-AS1 Gene

    This gene is overexpressed in Colon - Transverse (23.6), Small Intestine - Terminal Ileum (9.8), and Pituitary (4.0).

    SOURCE GeneReport for Unigene cluster for CDKN2B-AS1 Gene Hs.493614

    genes like me logo Genes that share expressions with CDKN2B-AS1: view

    In Situ Assay Products

    No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for CDKN2B-AS1 Gene

    Orthologs for CDKN2B-AS1 Gene

    Evolution for CDKN2B-AS1 Gene

    Gene Tree for CDKN2B-AS1 (if available)
    Gene Tree for CDKN2B-AS1 (if available)

    No data available for Orthologs for CDKN2B-AS1 Gene

    Paralogs for CDKN2B-AS1 Gene

    No data available for Paralogs for CDKN2B-AS1 Gene

    Variants for CDKN2B-AS1 Gene

    Sequence variations from dbSNP and Humsavar for CDKN2B-AS1 Gene

    SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
    rs490005 -- 22,020,494(-) ctctg(C/T)tggtg intron-variant
    rs496892 -- 22,024,352(-) aatcc(A/G)ctagc intron-variant
    rs504318 -- 22,024,024(-) ctcaa(A/T)aatca intron-variant
    rs575427 -- 22,011,478(-) AATTC(C/T)CTGAT intron-variant
    rs598664 -- 22,027,552(-) TTTTT(A/G)GATGT intron-variant

    Structural Variations from Database of Genomic Variants (DGV) for CDKN2B-AS1 Gene

    Variant ID Type Subtype PubMed ID
    nsv8426 CNV Loss 18304495
    nsv892745 CNV Gain 21882294
    nsv892746 CNV Loss 21882294
    nsv892747 CNV Gain 21882294
    nsv824877 CNV Loss 20364138
    nsv892748 CNV Loss 21882294
    esv1998859 CNV Deletion 18987734
    esv2738282 CNV Deletion 23290073
    dgv1306e201 CNV Deletion 23290073
    nsv416308 CNV Loss 16902084
    esv1002544 CNV Insertion 20482838
    esv2589724 CNV Deletion 19546169

    Relevant External Links for CDKN2B-AS1 Gene

    HapMap Linkage Disequilibrium report
    Human Gene Mutation Database (HGMD)

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDKN2B-AS1 Gene

    Disorders for CDKN2B-AS1 Gene

    genes like me logo Genes that share disorders with CDKN2B-AS1: view

    No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CDKN2B-AS1 Gene

    Publications for CDKN2B-AS1 Gene

    1. Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p. (PMID: 18048406) Broadbent H.M. … Watkins H. (Hum. Mol. Genet. 2008) 2 3
    2. Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1. (PMID: 21532571) Burdon K.P. … Craig J.E. (Nat. Genet. 2011) 2 3
    3. Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway. (PMID: 23416462) Wan G. … Lu X. (Cell. Signal. 2013) 2 3
    4. Characterization of a germ-line deletion, including the entire INK4/ARF locus, in a melanoma-neural system tumor family: identification of ANRIL, an antisense noncoding RNA whose expression coclusters with ARF. (PMID: 17440112) Pasmant E. … BiA"che I. (Cancer Res. 2007) 2 3
    5. Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. (PMID: 17463249) Zeggini E. … Hattersley A.T. (Science 2007) 3

    Products for CDKN2B-AS1 Gene

    Sources for CDKN2B-AS1 Gene

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