CDKN2AIPNL Gene
protein-coding GIFtS: 34
GCID: GC05M133756
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CDKN2A interacting protein N-terminal like
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Aliases
for CDKN2AIPNL gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CDKN2A Interacting Protein N-Terminal Like1 2 | | CDKN2A-Interacting Protein N-Terminal-Like Protein2 3 | | MGC130171 | | CDKN2AIP N-Terminal-Like Protein2 |
Export aliases for CDKN2AIPNL gene to outside databasesPrevious GC identifer: GC05M128922 |
Summaries
for CDKN2AIPNL gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CDKN2AIPNL gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_034772.6
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CDKN2AIPNL gene promoter:
AML1a GCNF Olf-1 Lmo2 FOXJ2 (long isoform) GCNF-1 PPAR-gamma2 FOXJ2 GCNF-2 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDKN2AIPNL
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDKN2AIPNL |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q31.1 Ensembl cytogenetic band: 5q31.1 HGNC cytogenetic band: 5q31.1CDKN2AIPNL Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M133756: view genomic region
(about GC identifiers)
Start:
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133,737,756 bp from pter |
End:
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133,747,598 bp from pter |
Size:
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9,843 bases |
Orientation:
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minus strand |
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Proteins
for CDKN2AIPNL gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: C2AIL_HUMAN, Q96HQ2 (See
protein sequence)Recommended Name: CDKN2AIP N-terminal-like protein Size: 116 amino acids; 13196 Da
Secondary accessions: Q8WVE3Alternative splicing: 2 isoforms: Q96HQ2-1 Q96HQ2-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CDKN2AIPNL: NX_Q96HQ2
CDKN2AIPNL Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_542387.1
ENSEMBL proteins: ENSP00000394183 ENSP00000378456
Human Recombinant Protein Products:
CDKN2AIPNL Antibody Products:
Assay Products for CDKN2AIPNL: |
Protein
Domains /
Families
for CDKN2AIPNL gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDKN2AIPNL for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96HQ2ProtoNet protein and cluster: Q96HQ2 UniProtKB/Swiss-Prot: C2AIL_HUMAN, Q96HQ2Similarity: Belongs to the CARF family |
Function
for CDKN2AIPNL gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDKN2AIPNL (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDKN2AIPNL
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for CDKN2AIPNL | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDKN2AIPNL |
|
Pathways & Interactions
for CDKN2AIPNL gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDKN2AIPNL
|
Drugs & Compounds
for CDKN2AIPNL gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CDKN2AIPNL
Search CenterWatch for drugs/clinical trials and news about CDKN2AIPNL / C2AIL
|
Transcripts
for CDKN2AIPNL gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDKN2AIPNL gene: NM_080656.2 Unigene Cluster for CDKN2AIPNL: CDKN2A interacting protein N-terminal like Hs.156506 [show with all ESTs]Unigene Representative Sequence: NM_0806562 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000458198(uc011cxs.2) ENST00000395009
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDKN2AIPNL (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDKN2AIPNL
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CDKN2AIPNL (NM_080656) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDKN2AIPNL | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDKN2AIPNL |
Additional cDNA sequence: AK057925.1 BC008293.1 BC018086.1 6 DOTS entries: DT.86846428 DT.202096 DT.97838822 DT.91713079 DT.95126629 DT.100712520 24/82 AceView cDNA sequences (see all 82): CR591520 BU621747 CD722093 AW439849 AI377680 CR612048 CR602620 BU506898 BU163724 BX335513 AI261644 BE396801 AK057925 CN483972 BQ670189 BU159010 CR604625 CR612735 AI341611 AI885154 AW590901 CR616012 BE855534 BX439619
GeneLoc Exon Structure
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Expression
for CDKN2AIPNL gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CDKN2AIPNL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGGCGGACA
About this image
See CDKN2AIPNL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDKN2AIPNL
SOURCE GeneReport for Unigene cluster: Hs.156506
SABiosciences Custom PCR Arrays for CDKN2AIPNL
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDKN2AIPNL
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CDKN2AIPNL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDKN2AIPNL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDKN2AIPNL |
Orthologs
for CDKN2AIPNL gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of chordates.
Orthologs for CDKN2AIPNL gene from 3/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Cdkn2aipnl1 , 5 |
CDKN2A interacting protein N-terminal like1, 5 |
89.08(n)1
96.55(a)1 |
|
11 (31.78 cM)5
526261 NM_029976.31 NP_084252.11
519676615 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.271362 |
Xenopus laevis cDNA clone IMAGE6881328, partial cds |
74.69(n) |
|
BC053806.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
cdkn2aipnl1 |
CDKN2A interacting protein N-terminal like |
64.76(n)
53.33(a) |
|
450034 NM_001006055.1 NP_001006055.1 |
ENSEMBL Gene Tree for CDKN2AIPNL (if available)
TreeFam Gene Tree for CDKN2AIPNL (if available) |
Paralogs
for CDKN2AIPNL gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CDKN2AIPNL gene
- CDKN2AIP2 NKRF2
1 SIMAP similar gene for CDKN2AIPNL using alignment to 1 protein entry: C2AIL_HUMAN:CDKN2AIP
CDKN2AIPNL for paralogs About GeneDecksing
3 Pseudogenes.org Pseudogenes for CDKN2AIPNL
PGOHUM00000248373 PGOHUM00000244458 PGOHUM00000240000
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Genomic Variants
for CDKN2AIPNL gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDKN2AIPNL (133737756 - 133747598 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CDKN2AIPNL: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDKN2AIPNL |
|
Disorders
/ Diseases
for CDKN2AIPNL gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CDKN2AIPNL gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDKN2AIPNL gene integrated from 9 sources:
(articles sorted by number of sources associating them with CDKN2AIPNL) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for CDKN2AIPNL gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CDKN2AIPNL gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CDKN2AIPNL gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CDKN2AIPNL gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CDKN2AIPNL | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for CDKN2AIPNL gene:
Search GeneIP for patents involving CDKN2AIPNL
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CDKN2AIPNL gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDKN2AIPNL | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDKN2AIPNL | | | OriGene Protein Over-expression Lysate for CDKN2AIPNL | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDKN2AIPNL | | OriGene 3'-UTR Clone for CDKN2AIPNL | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDKN2AIPNL | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDKN2AIPNL | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CDKN2AIPNL | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDKN2AIPNL | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDKN2AIPNL | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDKN2AIPNL | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDKN2AIPNL | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDKN2AIPNL | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDKN2AIPNL |
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 | | | CDKN2AIPNL Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDKN2AIPNL |
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