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Aliases for CDKN2AIPNL Gene

Aliases for CDKN2AIPNL Gene

  • CDKN2A Interacting Protein N-Terminal Like 2 3 5
  • CDKN2A-Interacting Protein N-Terminal-Like Protein 4

External Ids for CDKN2AIPNL Gene

Previous GeneCards Identifiers for CDKN2AIPNL Gene

  • GC05M133756
  • GC05M128922

Summaries for CDKN2AIPNL Gene

GeneCards Summary for CDKN2AIPNL Gene

CDKN2AIPNL (CDKN2A Interacting Protein N-Terminal Like) is a Protein Coding gene. An important paralog of this gene is CDKN2AIP.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDKN2AIPNL Gene

Genomics for CDKN2AIPNL Gene

Regulatory Elements for CDKN2AIPNL Gene

Enhancers for CDKN2AIPNL Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around CDKN2AIPNL on UCSC Golden Path with GeneCards custom track

Genomic Location for CDKN2AIPNL Gene

134,402,065 bp from pter
134,414,603 bp from pter
12,539 bases
Minus strand

Genomic View for CDKN2AIPNL Gene

Genes around CDKN2AIPNL on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CDKN2AIPNL Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CDKN2AIPNL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDKN2AIPNL Gene

Proteins for CDKN2AIPNL Gene

  • Protein details for CDKN2AIPNL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    CDKN2AIP N-terminal-like protein
    Protein Accession:
    Secondary Accessions:
    • Q8WVE3

    Protein attributes for CDKN2AIPNL Gene

    116 amino acids
    Molecular mass:
    13196 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CDKN2AIPNL Gene


neXtProt entry for CDKN2AIPNL Gene

Post-translational modifications for CDKN2AIPNL Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CDKN2AIPNL Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CDKN2AIPNL Gene

Domains & Families for CDKN2AIPNL Gene

Protein Domains for CDKN2AIPNL Gene


Suggested Antigen Peptide Sequences for CDKN2AIPNL Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the CARF family.
  • Belongs to the CARF family.
genes like me logo Genes that share domains with CDKN2AIPNL: view

No data available for Gene Families for CDKN2AIPNL Gene

Function for CDKN2AIPNL Gene

Phenotypes for CDKN2AIPNL Gene

GenomeRNAi human phenotypes for CDKN2AIPNL:
genes like me logo Genes that share phenotypes with CDKN2AIPNL: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CDKN2AIPNL Gene

Localization for CDKN2AIPNL Gene

Subcellular locations from

Jensen Localization Image for CDKN2AIPNL Gene COMPARTMENTS Subcellular localization image for CDKN2AIPNL gene
Compartment Confidence
cytosol 3
nucleus 3
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CDKN2AIPNL Gene

Pathways & Interactions for CDKN2AIPNL Gene

SuperPathways for CDKN2AIPNL Gene

No Data Available

Interacting Proteins for CDKN2AIPNL Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000394183 Q96HQ2-C2AIL_HUMAN for CDKN2AIPNL Gene via STRING IID

Gene Ontology (GO) - Biological Process for CDKN2AIPNL Gene


No data available for Pathways by source and SIGNOR curated interactions for CDKN2AIPNL Gene

Drugs & Compounds for CDKN2AIPNL Gene

No Compound Related Data Available

Transcripts for CDKN2AIPNL Gene


Unigene Clusters for CDKN2AIPNL Gene

CDKN2A interacting protein N-terminal like:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CDKN2AIPNL Gene

No ASD Table

Relevant External Links for CDKN2AIPNL Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CDKN2AIPNL Gene

mRNA expression in normal human tissues for CDKN2AIPNL Gene

Protein differential expression in normal tissues from HIPED for CDKN2AIPNL Gene

This gene is overexpressed in Peripheral blood mononuclear cells (10.7) and Monocytes (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CDKN2AIPNL Gene

NURSA nuclear receptor signaling pathways regulating expression of CDKN2AIPNL Gene:


SOURCE GeneReport for Unigene cluster for CDKN2AIPNL Gene:

genes like me logo Genes that share expression patterns with CDKN2AIPNL: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for CDKN2AIPNL Gene

Orthologs for CDKN2AIPNL Gene

This gene was present in the common ancestor of animals.

Orthologs for CDKN2AIPNL Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CDKN2AIPNL 34
  • 91.67 (n)
  • 96.55 (a)
  • 95 (a)
(Canis familiaris)
Mammalia CDKN2AIPNL 34
  • 92.24 (n)
  • 99.14 (a)
  • 99 (a)
(Mus musculus)
Mammalia Cdkn2aipnl 34
  • 89.08 (n)
  • 96.55 (a)
Cdkn2aipnl 16
Cdkn2aipnl 35
  • 97 (a)
(Pan troglodytes)
Mammalia CDKN2AIPNL 34
  • 100 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Cdkn2aipnl 34
  • 88.51 (n)
  • 95.69 (a)
(Monodelphis domestica)
Mammalia CDKN2AIPNL 35
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 2 (a)
(Anolis carolinensis)
Reptilia CDKN2AIPNL 35
  • 65 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cdkn2aipnl 34
  • 65.22 (n)
  • 59.78 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.27136 34
(Danio rerio)
Actinopterygii cdkn2aipnl 34
  • 64.76 (n)
  • 53.33 (a)
cdkn2aipnl 35
  • 49 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.7108 34
fruit fly
(Drosophila melanogaster)
Insecta CG31301 35
  • 5 (a)
Species where no ortholog for CDKN2AIPNL was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CDKN2AIPNL Gene

Gene Tree for CDKN2AIPNL (if available)
Gene Tree for CDKN2AIPNL (if available)

Paralogs for CDKN2AIPNL Gene

Paralogs for CDKN2AIPNL Gene

(1) SIMAP similar genes for CDKN2AIPNL Gene using alignment to 1 proteins: Pseudogenes for CDKN2AIPNL Gene

genes like me logo Genes that share paralogs with CDKN2AIPNL: view

Variants for CDKN2AIPNL Gene

Sequence variations from dbSNP and Humsavar for CDKN2AIPNL Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs184485 -- 134,402,457(+) atcgc(C/G)ccact utr-variant-3-prime
rs328042 -- 134,401,584(+) GTACA(G/T)AACAG downstream-variant-500B
rs328043 -- 134,409,707(+) ACAAT(A/G)CATAA intron-variant
rs11939 -- 134,402,697(+) TTTAT(A/T)AATAC utr-variant-3-prime
rs10067953 -- 134,402,776(+) AGACA(C/G)AGTCC utr-variant-3-prime

Variation tolerance for CDKN2AIPNL Gene

Residual Variation Intolerance Score: 45.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.19; 4.22% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CDKN2AIPNL Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CDKN2AIPNL Gene

Disorders for CDKN2AIPNL Gene

Relevant External Links for CDKN2AIPNL

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CDKN2AIPNL Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDKN2AIPNL Gene

Publications for CDKN2AIPNL Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65
  3. TRIM65 regulates microRNA activity by ubiquitination of TNRC6. (PMID: 24778252) Li S. … Dorf M.E. (Proc. Natl. Acad. Sci. U.S.A. 2014) 3 65
  4. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PMID: 22814378) Van Damme P. … Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012) 4 65
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65

Products for CDKN2AIPNL Gene

Sources for CDKN2AIPNL Gene

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