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Aliases for CDKN2A-AS1 Gene

Subcategory (RNA class) for CDKN2A-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for CDKN2A-AS1 Gene

  • CDKN2A Antisense RNA 1 (Head To Head) 2 3 5
  • C9orf53 3 4
  • Chromosome 9 Open Reading Frame 53 2
  • CDKN2A Antisense Gene Protein 1 4
  • Susceptibility Protein NSG-X 3
  • CDKN2A Antisense RNA 1 4
  • Protein CDKN2A-AS1 4
  • BA149I2.3 3

External Ids for CDKN2A-AS1 Gene

Previous HGNC Symbols for CDKN2A-AS1 Gene

  • C9orf53

Summaries for CDKN2A-AS1 Gene

GeneCards Summary for CDKN2A-AS1 Gene

CDKN2A-AS1 (CDKN2A Antisense RNA 1 (Head To Head)) is an RNA Gene, and is affiliated with the non-coding RNA class.

Additional gene information for CDKN2A-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDKN2A-AS1 Gene

Genomics for CDKN2A-AS1 Gene

Regulatory Elements for CDKN2A-AS1 Gene

Enhancers for CDKN2A-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H021989 1.3 Ensembl ENCODE dbSUPER 13.1 +23.3 23253 1 ZBTB21 SUZ12 ZFHX2 GLIS2 ZNF366 ZSCAN5C PATZ1 ZNF600 KLF8 ZBTB20 KLHL9 CDKN2A-AS1 UBA52P6 ENSG00000265194 MTAP CDKN2B CDKN2B-AS1 PIR47863 GC09M021977
GH09H021986 1.3 Ensembl ENCODE dbSUPER 13.1 +20.8 20776 2 TBP PKNOX1 ZSCAN4 NFRKB RFX5 YY1 POLR2A ZSCAN5C MAFK ZBTB20 CDKN2B CDKN2A-AS1 UBA52P6 CDKN2B-AS1 PIR47863 GC09M021977
GH09H022039 1 Ensembl ENCODE 11.7 +74.1 74138 3 SOX5 SOX13 SMARCE1 GATAD2A FOXA2 FOXA3 CEBPB CEBPG DPF2 EP300 CDKN2B CDKN2A CDKN2B-AS1 MTAP CDKN2A-AS1 UBA52P6 ENSG00000274055
GH09H022124 0.9 ENCODE 11.2 +157.8 157760 1 TBP PKNOX1 FOXA2 ARNT FEZF1 ZNF366 KLF7 SMARCC1 OVOL3 CEBPB CDKN2A CDKN2A-AS1 ENSG00000277653 GC09M022195
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CDKN2A-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CDKN2A-AS1 Gene

21,966,929 bp from pter
21,967,754 bp from pter
826 bases
Plus strand

Genomic View for CDKN2A-AS1 Gene

Genes around CDKN2A-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CDKN2A-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CDKN2A-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDKN2A-AS1 Gene

Proteins for CDKN2A-AS1 Gene

  • Protein details for CDKN2A-AS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Susceptibility protein NSG-x
    Protein Accession:
    Secondary Accessions:
    • Q5VVJ4

    Protein attributes for CDKN2A-AS1 Gene

    79 amino acids
    Molecular mass:
    8851 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CDKN2A-AS1 Gene

Post-translational modifications for CDKN2A-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for CDKN2A-AS1 Gene

Domains & Families for CDKN2A-AS1 Gene

Protein Domains for CDKN2A-AS1 Gene


Suggested Antigen Peptide Sequences for CDKN2A-AS1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CDKN2A-AS1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for CDKN2A-AS1 Gene

Function for CDKN2A-AS1 Gene

Phenotypes From GWAS Catalog for CDKN2A-AS1 Gene

Phenotypes for CDKN2A-AS1 Gene

genes like me logo Genes that share phenotypes with CDKN2A-AS1: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for CDKN2A-AS1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CDKN2A-AS1 Gene

Localization for CDKN2A-AS1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CDKN2A-AS1 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CDKN2A-AS1 Gene

Pathways & Interactions for CDKN2A-AS1 Gene

SuperPathways for CDKN2A-AS1 Gene

No Data Available

Interacting Proteins for CDKN2A-AS1 Gene

Gene Ontology (GO) - Biological Process for CDKN2A-AS1 Gene


No data available for Pathways by source and SIGNOR curated interactions for CDKN2A-AS1 Gene

Drugs & Compounds for CDKN2A-AS1 Gene

No Compound Related Data Available

Transcripts for CDKN2A-AS1 Gene

mRNA/cDNA for CDKN2A-AS1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for CDKN2A-AS1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for CDKN2A-AS1 Gene

No ASD Table

Relevant External Links for CDKN2A-AS1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CDKN2A-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CDKN2A-AS1 Gene

Protein differential expression in normal tissues from HIPED for CDKN2A-AS1 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CDKN2A-AS1 Gene

Protein tissue co-expression partners for CDKN2A-AS1 Gene

genes like me logo Genes that share expression patterns with CDKN2A-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CDKN2A-AS1 Gene

Orthologs for CDKN2A-AS1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CDKN2A-AS1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia C9orf53 34
  • 99 (a)
Species where no ortholog for CDKN2A-AS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CDKN2A-AS1 Gene

Gene Tree for CDKN2A-AS1 (if available)
Gene Tree for CDKN2A-AS1 (if available)

Paralogs for CDKN2A-AS1 Gene

No data available for Paralogs for CDKN2A-AS1 Gene

Variants for CDKN2A-AS1 Gene

Sequence variations from dbSNP and Humsavar for CDKN2A-AS1 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs749753811 Likely benign 21,968,232(+) TTTCA(A/G)TCGGG downstream-variant-500B, reference, synonymous-codon, utr-variant-3-prime
rs778871932 Likely benign 21,968,241(+) GGGAT(A/G)TCTGC downstream-variant-500B, reference, synonymous-codon, utr-variant-3-prime
rs863224604 Uncertain significance 21,968,220(-) AACCA(G/T)AGAGG downstream-variant-500B, utr-variant-3-prime
rs876660514 Uncertain significance 21,968,246(-) CCTCT(C/G)CAGAC intron-variant, downstream-variant-500B
rs1000383858 -- 21,965,324(+) TTCTG(C/T)AGCCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for CDKN2A-AS1 Gene

Variant ID Type Subtype PubMed ID
esv2764150 CNV gain+loss 21179565
nsv1018514 CNV gain 25217958
nsv8426 CNV loss 18304495

Variation tolerance for CDKN2A-AS1 Gene

Gene Damage Index Score: 0.05; 1.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CDKN2A-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDKN2A-AS1 Gene

Disorders for CDKN2A-AS1 Gene

Relevant External Links for CDKN2A-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CDKN2A-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CDKN2A-AS1 Gene

Publications for CDKN2A-AS1 Gene

  1. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray SJ … Dunham I (Nature 2004) 3 4 60
  2. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. (PMID: 21048031) Casabonne D … de Sanjose S (Haematologica 2011) 3 60
  3. The contribution of a 9p21.3 variant, a KIF6 variant, and C-reactive protein to predicting risk of myocardial infarction in a prospective study. (PMID: 21406102) Shiffman D … Psaty BM (BMC cardiovascular disorders 2011) 3 60
  4. Six sequence variants on chromosome 9p21.3 are associated with a positive family history of myocardial infarction: a multicenter registry. (PMID: 21385355) Scheffold T … Forschungsverbund Herz-Kreislauf in NRW (Research Consortium Heart and Circulation in North Rhine-Westphalia) (BMC cardiovascular disorders 2011) 3 60
  5. Chromosome 9p21.3 genotype is associated with vascular dementia and Alzheimer's disease. (PMID: 19664850) Emanuele E … Politi P (Neurobiology of aging 2011) 3 60

Products for CDKN2A-AS1 Gene

Sources for CDKN2A-AS1 Gene

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