CDKL1 Gene
protein-coding GIFtS: 52
GCID: GC14M050796
|
|
cyclin-dependent kinase-like 1 (CDC2-related kinase)
| |
Aliases
for CDKL1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase)1 2 | | P422 | | KKIALRE1 2 | | CDC2-Related Kinase 12 | | Protein Kinase P42 KKIALRE2 3 | | Cyclin-Dependent Kinase-Like 12 | | Serine/Threonine-Protein Kinase KKIALRE2 3 | | Serine/Threonine Protein Kinase KKIALRE2 | | EC 2.7.11.223 8 | | EC 2.7.118 |
Export aliases for CDKL1 gene to outside databasesPrevious GC identifers: GC14M048118 GC14M044592 GC14M048786 GC14M049866 GC14M030921 |
Summaries
for CDKL1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CDKL1:
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulatesprimarily in the nucleus. Alternative splice variants encoding different protein isoforms have been described, buttheir full-length nature has not been determined. (provided by RefSeq, Jul 2008)
|
Genomic Views
for CDKL1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000014.8 NC_018925.1 NT_026437.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CDKL1 gene promoter:
USF1 GATA-3 Nkx2-2 HSF1 (long) USF2 USF-1:USF-2 USF-1 STAT3 HSF1short ZIC2/Zic2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDKL1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDKL1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 14q21.3 Ensembl cytogenetic band: 14q21.3 HGNC cytogenetic band: 14q21.3CDKL1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 14 GeneLoc Exon Structure GeneLoc location for GC14M050796: view genomic region
(about GC identifiers)
Start:
|
50,796,310 bp from pter |
End:
|
50,883,179 bp from pter |
Size:
|
86,870 bases |
Orientation:
|
minus strand |
|
Proteins
for CDKL1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CDKL1_HUMAN, Q00532 (See
protein sequence)Recommended Name: Cyclin-dependent kinase-like 1 Size: 357 amino acids; 41671 Da
Subcellular location: Cytoplasm. Nucleus
Sequence caution: Sequence=AAI04978.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Sequence=AAS00095.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=CAA47002.1;Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from  and Proteopedia  for CDKL1:4AGU (3D)
Secondary accessions: Q2M3A4 Q6QUA0 Q8WXQ5Alternative splicing: 2 isoforms: Q00532-1 Q00532-2 Explore the universe of human proteins at neXtProt for CDKL1: NX_Q00532
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q00532
4/7 DME Specific Peptides for CDKL1 (Q00532) (see all 7)
CDKL1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004187.2
ENSEMBL proteins: ENSP00000379176 ENSP00000431449 ENSP00000435044 ENSP00000216378
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CDKL1 for ontologies About GeneDecksing
CDKL1 Antibody Products:
Assay Products for CDKL1: |
Protein
Domains /
Families
for CDKL1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDKL1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q00532ProtoNet protein and cluster: Q00532 UniProtKB/Swiss-Prot: CDKL1_HUMAN, Q00532Domain: The [NKR]KIAxRE motif seems to be a cyclin-binding regionSimilarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamilySimilarity: Contains 1 protein kinase domain |
Function
for CDKL1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CDKL1_HUMAN, Q00532Catalytic activity: ATP + a protein = ADP + a phosphoproteinEnzyme Numbers (IUBMB): EC 2.7.11.221 2 EC 2.7.112
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDKL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDKL1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CDKL1 (NM_004196) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDKL1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDKL1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDKL1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004693 | cyclin-dependent protein kinase activity |
IEA | -- | | GO:0005524 | ATP binding |
IEA | -- |
CDKL1 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for CDKL1:
|
Pathways & Interactions
for CDKL1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDKL1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
5/6 Interacting proteins for CDKL1 (Q005323 ENSP000002163784) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
CDKL1 for ontologies About GeneDecksing
|
Drugs & Compounds
for CDKL1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CDKL1 for compounds About GeneDecksing
 Browse Tocris compounds for CDKL1
2 HMDB Compounds for CDKL1 About this table
1 Novoseek chemical compound relationship for CDKL1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tyrosine |
21.6 |
3 |
7579336 (2), 17472728 (1) |
Search CenterWatch for drugs/clinical trials and news about CDKL1
|
Transcripts
for CDKL1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDKL1 gene: NM_004196.3 Unigene Cluster for CDKL1: Cyclin-dependent kinase-like 1 (CDC2-related kinase) Hs.679430 [show with all ESTs]Unigene Representative Sequence: AF39002811 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000395834(uc001wxz.3) ENST00000525911 ENST00000534267 ENST00000216378
ENST00000356146(uc010anu.2) ENST00000542671 ENST00000529347 ENST00000528197
ENST00000531052 ENST00000530553 ENST00000534566
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDKL1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDKL1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CDKL1 (NM_004196) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDKL1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDKL1 |
Additional cDNA sequence: AF390028.1 AK308732.1 BC104977.1 X66358.1 8 DOTS entries: DT.40131479 DT.100018854 DT.120765466 DT.120765602 DT.40129014 DT.40277908 DT.91653511 DT.206768 24/35 AceView cDNA sequences (see all 35): BF439746 BM700097 AF390028 NM_004196 BX099583 CN478950 AL047521 AA927373 AW237555 BU737897 AL603471 AA334399 CA334835 AI333007 AK093741 AI632347 AA680410 BE700389 BP349057 AA043556 BF507529 BE700387 BX498224 X66358
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for CDKL1 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ |
|---|
|
| SP1: | | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 23 | ^ | 24 | ^ | 25 |
|---|
|
| SP1: | | | | | | | |
| SP2: | | | | | | | |
| SP3: | - | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for CDKL1
|
Expression
for CDKL1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CDKL1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGAACAGCTG
About this image
See CDKL1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDKL1
SOURCE GeneReport for Unigene cluster: Hs.679430
UniProtKB/Swiss-Prot: CDKL1_HUMAN, Q00532Tissue specificity: Highly expressed in kidney, and to a lower extent in ovary
SABiosciences Expression via Pathway-Focused PCR Array including CDKL1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDKL1
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDKL1 |
Orthologs
for CDKL1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CDKL1 gene from 5/24 species (see all 24) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CDKL11 |
cyclin-dependent kinase-like 1 (CDC2-related kinase) |
76.14(n)
83.81(a) |
|
423575 XM_421464.3 XP_421464.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CDKL16 |
-- |
85(a) |
1 ↔ 1 |
GL343627.1(150040-162601) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.156002 |
Transcribed sequence with weak similarity to protein more |
73.58(n) |
|
BM342227.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG72361 , 3 |
protein amino acid phosphorylation protein
serine/threonine more3
CG72361 |
57(a)3
57.84(n)1
60.88(a)1 |
|
25F33
337981 NM_001201773.11 NP_001188702.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y42A5A.43
CELE_Y42A5A.41 |
Eukaryotic protein kinase domain3
Protein Y42A5A.41 |
59(a)3
62.28(n)1
62.07(a)1 |
|
V(11108095-11109872)3
1898411 NM_073422.11 NP_505823.11 |
ENSEMBL Gene Tree for CDKL1 (if available)
TreeFam Gene Tree for CDKL1 (if available) |
Paralogs
for CDKL1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CDKL1 gene
- CDKL22 CDKL52 MOK2 CDKL32 MAK2 CDKL42 ICK2
18/70 SIMAP similar genes for CDKL1 using alignment to 4 protein entries: CDKL1_HUMAN (see all proteins)
(see all similar genes):CDKL2 CDKL4 CDC2 MARK3 CDK3 CDK2
CDK1 DYRK4 CDKL3 PCTK3 CDK16 DKFZp686L20222
MAPK7 AURKC CDK17 PCTK1 MAK CDK7
CDKL1 for paralogs About GeneDecksing
|
Genomic Variants
for CDKL1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 14 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDKL1 (50796310 - 50883179 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CDKL1
2 CNVs: 58676 66642 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDKL1 |
|
Disorders
/ Diseases
for CDKL1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 CDKL1 for disorders About MalaCards
CDKL1 for disorders About GeneDecksing
OMIM gene information: 603441
OMIM disorders: --
Human Genome Epidemiology (HuGE) Navigator: CDKL1 (1 document)
Export disorders for CDKL1 gene to outside databases
|
Publications
for CDKL1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDKL1 gene, integrated from 9 sources (see all 17):
(articles sorted by number of sources associating them with CDKL1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A family of human cdc2-related protein kinases. (PubMed id 1639063)1, 2, 3 Meyerson M.... Tsai L.-H. (1992)
- Molecular cloning of the epidermal growth factor-stimulated protein kinase p56 KKIAMRE. (PubMed id 9000130)1, 2, 9 Taglienti C.A.... Davis R.J. (1996)
- The distribution and biochemical properties of a Cdc2 -related kinase, KKIALRE, in normal and Alzheimer brains. (PubMed id 7595554)1, 3 Yen S.H....Dickson D.W. (1995)
- Evaluation of cyclin-dependent kinase-like 1 expressio n in breast cancer tissues and its regulation in cancer cell growth. (PubMed id 22804458)1 Tang L....Tang J. (2012)
- A role for Cdkl1 in the development of gastric cancer. (PubMed id 22369697)1 Sun W....Wang Q. (2012)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Common genetic variation and performance on standardi zed cognitive tests. (PubMed id 20125193)1 Cirulli E.T....Goldstein D.B. (2010)
- Patterns of somatic mutation in human cancer genomes. (PubMed id 17344846)2 Greenman C.... Stratton M.R. (2007)
- High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (2005)
- Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5/STK9) gene are associated with severe neurodevelopmental retardation. (PubMed id 15499549)1 Tao J.... Kalscheuer V.M. (2004)
|
External Searches for CDKL1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CDKL1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CDKL1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CDKL1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CDKL1 | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/cdkl1/ |
|
| | |
About This Section
| Patent Information for CDKL1 gene:
Search GeneIP for patents involving CDKL1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CDKL1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CDKL1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDKL1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDKL1 | | | OriGene Protein Over-expression Lysate for CDKL1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDKL1 | | OriGene 3'-UTR Clone for CDKL1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDKL1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDKL1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CDKL1 | | OriGene Custom Protein Services for CDKL1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDKL1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDKL1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDKL1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDKL1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDKL1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDKL1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CDKL1 |
| |  |  |  |  | | | | |
 |
 |
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 | | | CDKL1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDKL1 |
|  |  |  | | | | ThermoFisher Antibody for CDKL1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDKL1 |
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