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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CDK5RAP1 Gene

protein-coding   GIFtS: 53
GCID: GC20M031946

CDK5 regulatory subunit associated protein 1

(Previous name: chromosome 20 open reading frame 34 )
(Previous symbol: C20orf34)
 Explore 4 diseases affiliated with
CDK5RAP1 via our new
 Human Malady Compendium 
Biological research products
for CDK5RAP1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
CDK5 Regulatory Subunit Associated Protein 11 2     CDK5 Activator-Binding Protein C422 3
C20orf341 2 3     Chromosome 20 Open Reading Frame 341
C421 2     CDK5RAP1.32
CGI-051 2     CDK5RAP1.42
HSPC1671 2     CDK5 Regulatory Subunit-Associated Protein 12

External Ids:    HGNC: 158801   Entrez Gene: 516542   Ensembl: ENSG000001013917   OMIM: 6082005   UniProtKB: Q96SZ63   

Export aliases for CDK5RAP1 gene to outside databases

Previous GC identifers: GC20M031705 GC20M032615 GC20M032662 GC20M031410 GC20M028734


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CDK5RAP1:
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic
subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore
may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length
natures of only two have been determined. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CK5P1_HUMAN, Q96SZ6
Function: Specifically inhibits CDK5 activation by CDK5R1

Gene Wiki entry for CDK5RAP1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CDK5RAP1 gene promoter:
         Max1   ISGF-3   STAT1   AML1a   Pax-5   STAT1beta   Arnt   GATA-1   STAT1alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCDK5RAP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CDK5RAP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDK5RAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20pter-q11.23   Ensembl cytogenetic band:  20q11.21   HGNC cytogenetic band: 20q11.21

CDK5RAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CDK5RAP1 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20M031946:  view genomic region     (about GC identifiers)

Start:
31,946,645 bp from pter      End:
31,989,367 bp from pter
Size:
42,723 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CK5P1_HUMAN, Q96SZ6 (See protein sequence)
Recommended Name: CDK5 regulatory subunit-associated protein 1  
Size: 601 amino acids; 67689 Da
Cofactor: Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable
S-adenosyl-L-methionine (By similarity)
Subunit: Interacts with CDK5R1 (p35 form). CDK5RAP1, CDK5RAP2 and CDK5RAP3 show competitive binding to CDK5R1. Forms a
complex with CDK5R1 and CDK5
Sequence caution: Sequence=AAD34147.1; Type=Frameshift; Positions=3, 32, 128, 133, 569; Sequence=AAF29131.1;
Type=Frameshift; Positions=213, 244, 267, 282; Sequence=BAB55120.1; Type=Erroneous termination; Positions=500;
Note=Translated as Glu;
Secondary accessions: A8K7R0 Q5QP46 Q5QP47 Q5QP48 Q9BVG6 Q9BWZ5 Q9H859 Q9NZZ9 Q9Y3F0
Alternative splicing: 4 isoforms:  Q96SZ6-1   Q96SZ6-2   Q96SZ6-3   Q96SZ6-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CDK5RAP1: NX_Q96SZ6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96SZ6

  • CDK5RAP1 Protein expression data from MOPED and PaxDb:    About this image 
    CDK5RAP1 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_057166.3  NP_057492.2  

    ENSEMBL proteins: 
     ENSP00000409474   ENSP00000217372   ENSP00000350558   ENSP00000341840   ENSP00000408133  
     ENSP00000439034  

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    Uscn Proteins for CDK5RAP1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--

    CDK5RAP1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CDK5RAP1 for domains           About GeneDecksing

    5/8 InterPro domains/families (see all 8):
     IPR005839 Methylthiotransferase
     IPR020612 Methylthiotransferase_CS
     IPR013848 Methylthiotransferase_N
     IPR007197 rSAM
     IPR006638 Elp3/MiaB/NifB

    Graphical View of Domain Structure for InterPro Entry Q96SZ6

    ProtoNet protein and cluster: Q96SZ6

    3 Blocks protein families:
    IPB002792 Deoxyribonuclease/rho motif-related TRAM
    IPB005839 Protein of unknown function UPF0004
    IPB006638 Elongator protein 3/MiaB/NifB


    UniProtKB/Swiss-Prot: CK5P1_HUMAN, Q96SZ6
    Similarity: Belongs to the methylthiotransferase family. MiaB subfamily
    Similarity: Contains 1 MTTase N-terminal domain
    Similarity: Contains 1 TRAM domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CK5P1_HUMAN, Q96SZ6
    Function: Specifically inhibits CDK5 activation by CDK5R1

         Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016740transferase activity IEA--
    GO:0019901protein kinase binding NAS10721722
    GO:0032403protein complex binding IEA--
    GO:0046872metal ion binding IEA--
    GO:00515394 iron, 4 sulfur cluster binding IEA--
         
    CDK5RAP1 for ontologies           About GeneDecksing


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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK5RAP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CDK5RAP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/9 Interacting proteins for CDK5RAP1 (Q96SZ61, 3 ENSP000002173724) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOSC5Q9NQT41, 3, ENSP000002212334EBI-372956,EBI-371876 I2D: score=2 STRING: ENSP00000221233
    EXOSC3Q9NQT51, 3, ENSP000003230464EBI-372956,EBI-371866 I2D: score=2 STRING: ENSP00000323046
    CDK5R1Q150783, ENSP000003184864I2D: score=2 STRING: ENSP00000318486
    CDK5Q005353, ENSP000002975184I2D: score=1 STRING: ENSP00000297518
    UVRAGQ9P2Y53I2D: score=1 
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000079regulation of cyclin-dependent protein kinase activity ----
    GO:0006400tRNA modification IEA--
    GO:0007420brain development NAS10915792
    GO:0009451RNA modification ----
    GO:0045664regulation of neuron differentiation NAS10721722

    CDK5RAP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for CDK5RAP1

    1 HMDB Compound for CDK5RAP1    About this table
    CompoundSynonyms CAS #PubMed Ids
    S-Adenosylmethionine(3S)-5'-[(3-amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine (see all 16)29908-03-0--
    Search CenterWatch for drugs/clinical trials and news about CDK5RAP1 / CK5P1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CDK5RAP1 gene (2 alternative transcripts): 
    NM_016082.3  NM_016408.2  

    Unigene Cluster for CDK5RAP1:

    CDK5 regulatory subunit associated protein 1
    Hs.435952  [show with all ESTs]
    Unigene Representative Sequence: NM_016408
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000427097 ENST00000481964 ENST00000482967 ENST00000473997 ENST00000346416(uc002wyz.3 uc002wza.3 uc002wzc.1)
    ENST00000357886(uc010gek.3) ENST00000339269(uc010gem.3 uc010gen.3)
    ENST00000461710(uc002wzb.1) ENST00000498525 ENST00000496381 ENST00000460043
    ENST00000471264 ENST00000473791 ENST00000477105 ENST00000461356 ENST00000488723
    ENST00000452723(uc002wyy.3 uc010gel.3) ENST00000544843

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    Additional cDNA sequence: 

    AF161516.1 AK023992.1 AK027449.1 AK222745.1 AK292075.1 AK295342.1 AK309906.1 AK314532.1 
    AY462283.1 AY462284.1 BC001215.1 BC050706.1 

    20 DOTS entries:

    DT.214174  DT.100794395  DT.95172064  DT.101981101  DT.102822744  DT.120807552  DT.100036777  DT.99938826 
    DT.100709137  DT.100794393  DT.102822743  DT.100036773  DT.100036775  DT.120807581  DT.120807609  DT.120807630 
    DT.432723  DT.91742063  DT.97780922  DT.100794392 

    24/235 AceView cDNA sequences (see all 235):

    CA419171 NM_016082 CA306926 BU625454 CA489121 BM993888 BE264358 BM802394 
    AY462283 NM_016408 AI474982 BG875910 CA944982 BM713151 BE256695 AW246779 
    AI298397 BU629184 CA307792 BG331136 BU625050 AU104054 BM834342 AA723454 

    GeneLoc Exon Structure

    5/21 Alternative Splicing Database (ASD) splice patterns (SP) for CDK5RAP1 (see all 21)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e · 10f ^ 11a · 11b ^ 12a ·
    SP1:                          -                                               -                 -     -                                                     -   
    SP2:                          -                                               -                 -     -                                                     -   
    SP3:                          -     -                                         -                 -     -                                                     -   
    SP4:                          -                                               -                 -     -                                                     -   
    SP5:                          -                                               -                 -     -     -     -     -     -     -     -                 -   

    ExUns: 12b ^ 13 ^ 14 ^ 15a · 15b · 15c · 15d ^ 16
    SP1:                                -     -         
    SP2:                                -     -         
    SP3:                                -     -         
    SP4:                                                
    SP5:                                -     -         


    ECgene alternative splicing isoforms for CDK5RAP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CDK5RAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGGTGGAGA
    CDK5RAP1 Expression
    About this image
    See CDK5RAP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CDK5RAP1

    SOURCE GeneReport for Unigene cluster: Hs.435952

    UniProtKB/Swiss-Prot: CK5P1_HUMAN, Q96SZ6
    Tissue specificity: Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and
    pancreas

        SABiosciences Expression via Pathway-Focused PCR Array including CDK5RAP1: 
              Cell Cycle in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK5RAP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for CDK5RAP1 gene from 10/35 species (see all 35)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cdk5rap11 , 5 CDK5 regulatory subunit associated protein 11, 5 85.87(n)1
    88.03(a)1
      2 (76.46 cM)5
    669711  NM_025876.21  NP_080152.11 
     1543353805 
    chicken
    (Gallus gallus)
    Aves CDK5RAP11 CDK5 regulatory subunit associated protein 1 74.73(n)
    79.27(a)
      419292  XM_417464.3  XP_417464.1 
    lizard
    (Anolis carolinensis)
    Reptilia CDK5RAP16
    CDKAL16
    --
    71(a)
    22(a)
    1 ↔ 1
    possible ortholog
    GL343886.1(26490-47817)
    4(55500333-55581211)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.127382 Xenopus laevis transcribed sequence with weak similarity more 78.63(n)    BJ073828.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1627381 zgc:162738 63.22(n)
    68.26(a)
      558659  NM_001110379.1  NP_001103849.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG63451 CG6345 56.36(n)
    55.87(a)
      41271  NM_141745.3  NP_650002.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F25B5.51 Protein F25B5.5 55.11(n)
    51.62(a)
      175841  NM_065889.4  NP_498290.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G363901 Methylthiotransferase 53.84(n)
    51.72(a)
      829791  NM_119802.2  NP_195357.2 
    rice
    (Oryza sativa)
    Liliopsida Os11g05928001 hypothetical protein 56.7(n)
    53.64(a)
      4350829  NM_001074728.1  NP_001068196.1 
    E. coli
    (Escherichia coli)
    Gamma proteobacteria miaB6
    tRNA-i(6)A37 methylthiotransferase
    36(a)
    1 ↔ 1
    Chromosome(692754-694178)


    ENSEMBL Gene Tree for CDK5RAP1 (if available)
    TreeFam Gene Tree for CDK5RAP1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CDK5RAP1 gene
    CDKAL12  

    CDK5RAP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/763 NCBI SNPs in CDK5RAP1 are shown (see all 763    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 20 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs130382011,2
    C,F,H--31946260(+) GGGGGT/CTGTAA 2 -- ds50017Minor allele frequency- C:0.00NS EA NA 616
    rs1878092891,2
    --31946272(+) GGAAAA/GCAGAG 2 -- ds50010--------
    rs1475841791,2
    --31946397(+) TGCAGC/TGATAG 2 -- ds50010--------
    rs775403071,2
    F--31946410(+) AGCTAA/TGTCAG 2 -- ds50011Minor allele frequency- T:0.03EA 120
    rs1420926111,2
    --31946445(+) AGGTCA/GAGAGC 2 -- ds50010--------
    rs171246401,2
    C--31946537(+) GGGAGC/AAGTGT 2 -- ds50015Minor allele frequency- A:0.01NA 144
    rs1169179001,2
    --31946620(+) AAAAAC/TGAAGT 2 -- ds50011Minor allele frequency- T:0.01NA 120
    rs1389126601,2
    --31946630(+) TCAAAC/GTGAGA 2 -- ds50010--------
    rs1179883031,2
    F--31946631(+) CAAAGT/GGAGAG 2 -- ds50011Minor allele frequency- G:0.07EA 120
    rs171246421,2
    C,F,H--31946661(+) TTAGGT/AAAATT 2 -- ut31 ese39Minor allele frequency- A:0.08NA NS EA WA 658

    HapMap Linkage Disequilibrium report for CDK5RAP1 (31946645 - 31989367 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for CDK5RAP1
         1 CNV: 59022

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for CDK5RAP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CDK5RAP1 for disorders           About GeneDecksing

    OMIM gene information: 608200    OMIM disorders: --

    4 diseases for CDK5RAP1:    About MalaCards
    mikulicz disease    neuronitis    tuberculosis    mycobacterium tuberculosis

    1 disease from the University of Copenhagen DISEASES database for CDK5RAP1:
    Mikulicz disease
    Human Genome Epidemiology (HuGE) Navigator: CDK5RAP1 (4 documents)

    Export disorders for CDK5RAP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CDK5RAP1 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with CDK5RAP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of three novel neuronal Cdk5 activator binding proteins. (PubMed id 10721722)1, 2, 3, 9 Ching Y.-P.... Wang J.H. (2000)
    2. Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor. (PubMed id 11882646)1, 2, 3 Ching Y.-P.... Wang J.H. (2002)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Cloning, characterization and expression of CDK5RAP1_v3 and CDK5RAP1_v4, two novel splice variants of human CDK5RAP1. (PubMed id 15329498)1, 3 Zou X....Mao Y. (2004)
    6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    7. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
    8. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.H....Lin W. (2000)
    9. The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA. (PubMed id 22422838)1 Reiter V....Carell T. (2012)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51654 HGNC: 15880 AceView: CDK5RAP1 Ensembl:ENSG00000101391 euGenes: HUgn51654
    ECgene: CDK5RAP1 H-InvDB: CDK5RAP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CDK5RAP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CDK5RAP1 gene:
    Search GeneIP for patents involving CDK5RAP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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