Aliases for CDK5R2 Gene
External Ids for CDK5R2 Gene
Previous GeneCards Identifiers for CDK5R2 Gene
The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins. [provided by RefSeq, Jul 2008]
GeneCards Summary for CDK5R2 Gene
CDK5R2 (Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (P39)) is a Protein Coding gene. Diseases associated with CDK5R2 include Primary Microcephaly. Among its related pathways are Lissencephaly gene (LIS1) in neuronal migration and development and Neuroscience. GO annotations related to this gene include lipid binding and cyclin-dependent protein kinase 5 activator activity. An important paralog of this gene is CDK5R1.
UniProtKB/Swiss-Prot for CDK5R2 Gene
Activator of CDK5/TPKII.