CDK3 Gene
protein-coding GIFtS: 55
GCID: GC17P073996
|
|
cyclin-dependent kinase 3
| |
Aliases
for CDK3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cyclin-Dependent Kinase 31 2 | | Cell Division Protein Kinase 32 3 | | EC 2.7.11.223 8 | | CDKN33 | | EC 2.7.118 |
Export aliases for CDK3 gene to outside databasesPrevious GC identifers: GC17M073921 GC17P077001 GC17P074439 GC17P074572 GC17P074594 GC17P071486 GC17P073977 GC17P069422 |
Summaries
for CDK3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CDK3:
This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, inpart by activating members of the E2F family of transcription factors. The protein also associates with cyclin C andphosphorylates the retinoblastoma 1 protein to promote exit from G0. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: CDK3_HUMAN, Q00526Function: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle;involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylateshistone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities,and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in aRB1-independent manner
Gene Wiki entry for CDK3 (Cyclin-dependent kinase 3)
|
Genomic Views
for CDK3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CDK3 gene promoter:
HOXA9 HOXA9B AML1a Pax-5 RelA AP-4 CUTL1 Meis-1b NF-kappaB1 Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDK3
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDK3 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q25.1 Ensembl cytogenetic band: 17q25.1 HGNC cytogenetic band: 17q25.1CDK3 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P073996: view genomic region
(about GC identifiers)
Start:
|
73,996,987 bp from pter |
End:
|
74,002,080 bp from pter |
Size:
|
5,094 bases |
Orientation:
|
plus strand |
|
Proteins
for CDK3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CDK3_HUMAN, Q00526 (See
protein sequence)Recommended Name: Cyclin-dependent kinase 3 Size: 305 amino acids; 35046 Da
Subunit: Interacts with CABLES1 and CABLES2 (By similarity). Interacts with ATF1. Binding to CCNC/cyclin-C promotes RB1phosphorylation
1 PDB 3D structure from  and Proteopedia  for CDK3:1LFN (3D)
Explore the universe of human proteins at neXtProt for CDK3: NX_Q00526
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q00526
4/17 DME Specific Peptides for CDK3 (Q00526) (see all 17)
CDK3 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001249.1
ENSEMBL proteins: ENSP00000466237 ENSP00000410561 ENSP00000465062 ENSP00000400088
Human Recombinant Protein Products:
CDK3 Antibody Products:
Assay Products for CDK3: |
Protein
Domains /
Families
for CDK3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDK3 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q00526ProtoNet protein and cluster: Q00526 UniProtKB/Swiss-Prot: CDK3_HUMAN, Q00526Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamilySimilarity: Contains 1 protein kinase domain |
Function
for CDK3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CDK3_HUMAN, Q00526Function: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle;involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylateshistone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities,and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in aRB1-independent mannerCatalytic activity: ATP + a protein = ADP + a phosphoprotein Genatlas biochemistry entry for CDK3:cyclin dependent kinase 3,involved in cell cycle regulation (G1 to S transition),not complexing with any cyclin
Enzyme Numbers (IUBMB): EC 2.7.11.221 2 EC 2.7.112
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDK3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDK3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CDK3 (NM_001258) | |  | Sino Biological Human cDNA Clone for CDK3 | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDK3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDK3 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK3 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004693 | cyclin-dependent protein kinase activity |
IEA | -- | | GO:0005524 | ATP binding |
IEA | -- |
CDK3 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for CDK3:
|
Pathways & Interactions
for CDK3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell Cycle Control of Chromosomal Replication | | | 2 | GADD45 Pathway | |
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CDK3
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CDK3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/712 Interacting proteins for CDK3 (Q005262, 3 ENSP000004000884) via UniProtKB, MINT, STRING, and/or I2D (see all 712)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
CDK3 for ontologies About GeneDecksing
|
Drugs & Compounds
for CDK3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CDK3
2 HMDB Compounds for CDK3 About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| ADP | - adenosindiphosphorsaeure
- adenosine 5'-pyrophosphate
- adenosine diphosphate
- adenosine pyrophosphate
- adenosine-5'-diphosphate
- adenosine-5-diphosphate
- adenosine-diphosphate
- adp
(see top 1) | 58-64-0 | -- | | Adenosine triphosphate | - 5'-(tetrahydrogen triphosphate) Adenosine
- 5'-ATP
- ATP
- Adenosine 5'-triphosphate
- Adenosine 5'-triphosphorate
- Adenosine 5'-triphosphoric acid
- Adenosine triphosphate
- Adenosine triphosphic acid
- Adenylpyrophosphorate
- Adenylpyrophosphoric acid
- Adephos
- Adetol
- Adynol
- Atipi
- Atriphos
- Cardenosine
- Fosfobion
- Glucobasin
- Myotriphos
- Phosphobion
- Striadyne
- Triadenyl
- Triphosphaden
- Triphosphoric acid adenosine ester
(see top 1) | 56-65-5 | -- |
Search CenterWatch for drugs/clinical trials and news about CDK3
|
Transcripts
for CDK3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDK3 gene: NM_001258.2 Unigene Cluster for CDK3: Cyclin-dependent kinase 3 Hs.706766 [show with all ESTs]Unigene Representative Sequence: NR_0377094 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000588812 ENST00000425876 ENST00000586261 ENST00000448471
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDK3
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDK3
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CDK3 (NM_001258) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDK3 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDK3 |
Additional cDNA sequence: NR_037709.1 X66357.1 8 DOTS entries: DT.92434871 DT.302659 DT.95164072 DT.455141 DT.452082 DT.97768995 DT.121007869 DT.410755 24/138 AceView cDNA sequences (see all 138): BQ962463 BC047782 AI565655 CF128049 BM053101 BM907267 BU785194 BQ189457 AI131108 BM671003 CR604264 CK904002 BM053162 AU120188 BM706946 CD671351 BF308054 BM808772 BQ674947 AA648964 BM919842 BM696946 BM449587 BM807876
GeneLoc Exon Structure
|
Expression
for CDK3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CDK3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACGAGGGGT
About this image
See CDK3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDK3
SOURCE GeneReport for Unigene cluster: Hs.706766
UniProtKB/Swiss-Prot: CDK3_HUMAN, Q00526Tissue specificity: Expressed in cancer cell lines and glioblastoma tissue
SABiosciences Custom PCR Arrays for CDK3
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDK3
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CDK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDK3 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK3 |
Orthologs
for CDK3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CDK3 gene from 6/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CDK31 |
cyclin-dependent kinase 3 |
75.67(n)
81.33(a) |
|
429642 NM_001081706.2 NP_001075175.2 |
lizard
(Anolis carolinensis) |
Reptilia |
CDK36 |
-- |
79(a) |
1 ↔ 1 |
2(113303478-113317512) |
fruit fly
(Drosophila melanogaster) |
Insecta |
cdc23 |
G2/M transition of mitotic cell cycle
protein more |
65(a)
(best of 4) |
|
31D11 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
cdk-13 |
serine/threonine kinase (CDC2/CDKX
subfamily) |
63(a)
(best of 3) |
|
III(9819189-9820383) -- |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
CDKB1;26CDKB1;16(see all 4) |
cyclin-dependent kinase B1-1(see all 4) |
56(a)55(a)(see all 4) |
possible orthologpossible ortholog(see all 4) |
2(16152505-16154086) 3(20059796-20061438) |
rice
(Oryza sativa) |
Liliopsida |
---- |
cyclin-dependent kinase B2-1, putative, expressed |
59(a)46(a) |
possible orthologpossible ortholog |
1(38980259-38983035) 8(25417170-25419113) |
ENSEMBL Gene Tree for CDK3 (if available)
TreeFam Gene Tree for CDK3 (if available) |
Paralogs
for CDK3 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CDK3 gene
- CDK62 CDK182 CDK52 CDK152 CDK42 CDK12 CDK142 CDK162
- CDK22 CDK172
18/94 SIMAP similar genes for CDK3 using alignment to 3 protein entries: CDK3_HUMAN (see all proteins)
(see all similar genes):CDK1 CDC2 CDK5 DKFZp686L20222 CDK18 CDK2
PCTK1 PHKG2 CDK17 CDK16 STK3 PCTK3
CDK14 CDK15 NDUFA9 CDC2L2 CDK7 CDK6
CDK3 for paralogs About GeneDecksing
|
Genomic Variants
for CDK3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDK3 (73996987 - 74002080 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CDK3: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CDK3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CDK3 for disorders About GeneDecksing
OMIM gene information: 123828
OMIM disorders: --
7  diseases for CDK3: About MalaCardsretinoblastoma herpes simplex hepatocellular carcinoma glioblastoma
sarcoma carcinoma neuronitis
2 Novoseek disease relationships for CDK3 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
2 |
7882308 (2) |
| cancer |
0 |
2 |
18794154 (1), 7882308 (1) |
Export disorders for CDK3 gene to outside databases
|
Publications
for CDK3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDK3 gene, integrated from 9 sources (see all 48):
(articles sorted by number of sources associating them with CDK3) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A family of human cdc2-related protein kinases. (PubMed id 1639063)1, 2, 3, 9 Meyerson M.... Tsai L.-H. (1992)
- Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation. (PubMed id 18794154)1, 2, 9 Zheng D....Dong Z. (2008)
- Cyclin C/cdk3 promotes Rb-dependent G0 exit. (PubMed id 15084261)1, 2 Ren S. and Rollins B.J. (2004)
- Differential effects of cdk2 and cdk3 on the control of pRb and E2F function during G1 exit. (PubMed id 8846921)1, 2 Hofmann F. and Livingston D.M. (1996)
- Investigation of the cell cycle regulation of cdk3-associated kinase activity and the role of cdk3 in proliferation and transformation. (PubMed id 9811456)1, 9 Braun K....Hengstschlager M. (1998)
- ik3-1/Cables is a substrate for cyclin-dependent kinase 3 (cdk 3). (PubMed id 11733001)1, 9 Yamochi T....Matsuoka M. (2001)
- Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer. (PubMed id 7882308)1, 9 Bullrich F....Croce C.M. (1995)
- Phorbol ester inhibits the phosphorylation of the retinoblastoma protein without suppressing cyclin D-associated kinase in vascular smooth muscle cells. (PubMed id 8626531)1, 9 Sasaguri T....Ogata J. (1996)
- Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. (PubMed id 8242750)1, 9 Gyuris J.... Brent R. (1993)
- Cdk5 levels oscillate during the neuronal cell cycle: Cdh1 ubiquitination triggers proteosome-dependent degradation during S-phase. (PubMed id 22654103)1 Zhang J....Herrup K. (2012)
|
External Searches for CDK3 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CDK3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CDK3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CDK3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CDK3 | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/cdk3/ |
|
| | |
About This Section
| Patent Information for CDK3 gene:
Search GeneIP for patents involving CDK3
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CDK3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for CDK3 | | OriGene shRNA RFP for CDK3 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDK3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDK3 | | | OriGene Protein Over-expression Lysate for CDK3 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDK3 | | OriGene 3'-UTR Clone for CDK3 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDK3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDK3 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CDK3 | | OriGene Custom Protein Services for CDK3 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDK3 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDK3 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDK3 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDK3 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDK3 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDK3 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CDK3 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CDK3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK3 |
|  |  |  | | | | ThermoFisher Antibodies for CDK3 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDK3 |
|
|
|
|
