Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CDK11A Gene

Aliases for CDK11A Gene

  • Cyclin Dependent Kinase 11A 2 3 5
  • Galactosyltransferase-Associated Protein Kinase P58/GTA 3 4
  • Cell Division Cycle 2-Like 2 (PITSLRE Proteins) 2 3
  • PITSLRE Serine/Threonine-Protein Kinase CDC2L2 3 4
  • Cell Division Cycle 2-Like Protein Kinase 2 3 4
  • Cell Division Protein Kinase 11A 3 4
  • EC 2.7.11.22 4 61
  • CDC2L2 3 4
  • CDC2L3 3 4
  • PITSLRE Protein Kinase Beta SV16 Isoform 3
  • PITSLRE Protein Kinase Beta SV17 Isoform 3
  • PITSLRE Protein Kinase Beta SV18 Isoform 3
  • PITSLRE Protein Kinase Beta SV1 Isoform 3
  • PITSLRE Protein Kinase Beta SV2 Isoform 3
  • PITSLRE Protein Kinase Beta SV3 Isoform 3
  • PITSLRE Protein Kinase Beta SV6 Isoform 3
  • Cell Division Cycle 2-Like 2 2
  • PITSLRE Protein Kinase Beta 3
  • Cyclin-Dependent Kinase 11A 3
  • CDK11-P110 3
  • PITSLRE B 3
  • CDK11-P46 3
  • CDK11-P58 3
  • EC 2.7.11 61
  • PITSLREB 4
  • PITSLRE 3
  • P58GTA 3

External Ids for CDK11A Gene

Previous HGNC Symbols for CDK11A Gene

  • CDC2L3
  • CDC2L2

Previous GeneCards Identifiers for CDK11A Gene

  • GC01M001567
  • GC01M001634

Summaries for CDK11A Gene

Entrez Gene Summary for CDK11A Gene

  • This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

GeneCards Summary for CDK11A Gene

CDK11A (Cyclin Dependent Kinase 11A) is a Protein Coding gene. Diseases associated with CDK11A include Neuroblastoma. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDK11B.

UniProtKB/Swiss-Prot for CDK11A Gene

  • Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.

Gene Wiki entry for CDK11A Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CDK11A Gene

Genomics for CDK11A Gene

Regulatory Elements for CDK11A Gene

Enhancers for CDK11A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F001775 1 FANTOM5 ENCODE 6.4 -55.2 -55174 8.6 HDGF PKNOX1 CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A DMAP1 YY1 ZNF143 NADK CCNL2 LOC100288379 LOC105378949 MIR6727 ENSG00000230092 ENSG00000240731 FAM87B LINC00115 TMEM52
GH01F001868 1 Ensembl ENCODE 6.4 -145.8 -145849 4.0 HDGF HDAC1 ZNF121 GATA3 GATA2 CREM MTA2 CBFB JUNB TBX21 LOC105378949 CDK11A AGRN GC01P001866 GC01P001881
GH01F000939 0.5 ENCODE 5.4 +781.9 781898 6.3 ATF1 PKNOX1 FEZF1 ZNF2 ZNF121 GLIS2 KLF7 ZNF548 KLF13 ZNF263 ENSG00000229905 WBP1LP6 ENSG00000235146 MIR1302-2 CCNL2 NOC2L EGID-729587 LOC100288379 PLEKHN1 ENSG00000241180
GH01F002287 1.2 FANTOM5 Ensembl ENCODE 5.3 -567.1 -567149 7.8 ATF1 ARID4B YY1 ZNF121 GLIS2 FOS ZNF623 NFIL3 SMARCA4 RCOR2 MORN1 LOC100129534 MIR6727 ENSG00000240731 ENSG00000272455 SLC35E2 MIB2 CCNL2 SLC35E2B LOC100129381
GH01F000975 0.4 ENCODE 5 +748.0 747997 1.4 PKNOX1 SIN3A FEZF1 ZNF48 ZNF2 ZNF121 GLIS2 ELK1 KLF7 ZNF263 PERM1 ENSG00000272512 CDK11A GC01M000971 PLEKHN1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around CDK11A on UCSC Golden Path with GeneCards custom track

Promoters for CDK11A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001516778 52 2201 HDGF PKNOX1 CREB3L1 ARID4B SIN3A ZNF2 YY1 ZNF143 ZNF207 SP3

Genomic Location for CDK11A Gene

Chromosome:
1
Start:
1,702,730 bp from pter
End:
1,724,352 bp from pter
Size:
21,623 bases
Orientation:
Minus strand

Genomic View for CDK11A Gene

Genes around CDK11A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CDK11A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CDK11A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CDK11A Gene

Proteins for CDK11A Gene

  • Protein details for CDK11A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UQ88-CD11A_HUMAN
    Recommended name:
    Cyclin-dependent kinase 11A
    Protein Accession:
    Q9UQ88
    Secondary Accessions:
    • O95227
    • O95228
    • O96012
    • Q12821
    • Q12853
    • Q12854
    • Q2TAJ0
    • Q5QPR0
    • Q5QPR1
    • Q5QPR2
    • Q9UBC4
    • Q9UBI3
    • Q9UEI1
    • Q9UEI2
    • Q9UP53
    • Q9UP54
    • Q9UP55
    • Q9UP56
    • Q9UQ86
    • Q9UQ87
    • Q9UQ89

    Protein attributes for CDK11A Gene

    Size:
    783 amino acids
    Molecular mass:
    91362 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • The cleaved p110 isoform, p110C, binds to the serine/threonine kinase PAK1. The p58 isoform but not the p110 isoform or p110C interacts with CCND3. The p110 isoforms are found in large molecular weight complexes containing CCNL1 and SFRS7.
    Miscellaneous:
    • Duplicated gene. CDK11A and CDK11B encode almost identical protein kinases of 110 kDa that contain at their C-termini the open reading frame of a smaller 58 kDa isoform which is expressed following IRES-mediated alternative initiation of translation.
    SequenceCaution:
    • Sequence=AAC95297.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAC95298.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAC95299.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAC95300.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAC95302.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAC95303.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for CDK11A Gene

neXtProt entry for CDK11A Gene

Selected DME Specific Peptides for CDK11A Gene

Q9UQ88:
  • ILHRDLK
  • TDEIVALK
  • PLPIDPSMFPTWPAKSE
  • VKRGTSP
  • EQLERKR
  • GILKVGDFGLAREYGSP
  • YVEHDLKSLMETMK
  • QHPNIVTVREIVVGSNMDKI
  • QGCRSVEEFQCLNRIEEGTYGVVYRAKDK
  • EIVALKRLKMEKEKEGFPITSLREINT
  • PPEGGLGYSQLGDDDLKETGFHLTTTN
  • YRAPELLL

Post-translational modifications for CDK11A Gene

  • During apoptosis, induced by Fas or tumor necrosis factor, specific CKD11 p110 isoforms are cleaved by caspases to produce a protein (p110C) that contains the C-terminal kinase domain of the CDK11 proteins.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Domains & Families for CDK11A Gene

Gene Families for CDK11A Gene

Protein Domains for CDK11A Gene

Graphical View of Domain Structure for InterPro Entry

Q9UQ88

UniProtKB/Swiss-Prot:

CD11A_HUMAN :
  • Contains 1 protein kinase domain.
  • Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
Domain:
  • Contains 1 protein kinase domain.
Family:
  • Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
genes like me logo Genes that share domains with CDK11A: view

Function for CDK11A Gene

Molecular function for CDK11A Gene

UniProtKB/Swiss-Prot CatalyticActivity:
ATP + a protein = ADP + a phosphoprotein.
UniProtKB/Swiss-Prot EnzymeRegulation:
Phosphorylation at Thr-436 or Tyr-437 inactivates the enzyme, while phosphorylation at Thr-583 activates it.
UniProtKB/Swiss-Prot Function:
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
UniProtKB/Swiss-Prot Induction:
The p58 isoform is specifically induced in G2/M phase of the cell cycle.

Enzyme Numbers (IUBMB) for CDK11A Gene

Gene Ontology (GO) - Molecular Function for CDK11A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity NAS 9750192
GO:0004674 protein serine/threonine kinase activity IEA,IDA 12501247
GO:0004693 cyclin-dependent protein serine/threonine kinase activity IEA --
GO:0005524 ATP binding IDA 12501247
GO:0016301 kinase activity IEA --
genes like me logo Genes that share ontologies with CDK11A: view
genes like me logo Genes that share phenotypes with CDK11A: view

Animal Models for CDK11A Gene

MGI Knock Outs for CDK11A:

Animal Model Products

miRNA for CDK11A Gene

miRTarBase miRNAs that target CDK11A

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CDK11A Gene

Localization for CDK11A Gene

Subcellular locations from UniProtKB/Swiss-Prot for CDK11A Gene

Cytoplasm. Nucleus.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CDK11A Gene COMPARTMENTS Subcellular localization image for CDK11A gene
Compartment Confidence
nucleus 5
cytosol 4
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for CDK11A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 8195233
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with CDK11A: view

Pathways & Interactions for CDK11A Gene

genes like me logo Genes that share pathways with CDK11A: view

Pathways by source for CDK11A Gene

1 GeneTex pathway for CDK11A Gene

SIGNOR curated interactions for CDK11A Gene

Activates:

Gene Ontology (GO) - Biological Process for CDK11A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001558 regulation of cell growth IEP 10882096
GO:0006355 regulation of transcription, DNA-templated NAS 9750192
GO:0006468 protein phosphorylation IDA 12501247
GO:0006915 apoptotic process NAS 9750192
GO:0007049 cell cycle IEA --
genes like me logo Genes that share ontologies with CDK11A: view

Drugs & Compounds for CDK11A Gene

(2) Drugs for CDK11A Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Adenosine triphosphate Approved Nutra 0
Magnesium Nutra 0

(1) Additional Compounds for CDK11A Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with CDK11A: view

Transcripts for CDK11A Gene

mRNA/cDNA for CDK11A Gene

(7) REFSEQ mRNAs :
(18) Additional mRNA sequences :
(23) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CDK11A Gene

Cyclin-dependent kinase 11A:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CDK11A Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c ^ 10 ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b · 13c · 13d ^ 14 ^ 15a ·
SP1: -
SP2:
SP3:
SP4: - - - - - - - - - - - - - - -
SP5: - -
SP6: - -
SP7:
SP8:
SP9:
SP10:
SP11: -
SP12:
SP13:
SP14: -
SP15: - -

ExUns: 15b · 15c ^ 16a · 16b ^ 17 ^ 18a · 18b ^ 19 ^ 20a · 20b ^ 21a · 21b · 21c ^ 22a · 22b ^ 23a · 23b · 23c
SP1: - -
SP2: - -
SP3: - -
SP4: - - - - - - - - - - - -
SP5:
SP6:
SP7:
SP8: -
SP9: - -
SP10: - -
SP11:
SP12:
SP13:
SP14:
SP15:

Relevant External Links for CDK11A Gene

GeneLoc Exon Structure for
CDK11A
ECgene alternative splicing isoforms for
CDK11A

Expression for CDK11A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CDK11A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CDK11A Gene

This gene is overexpressed in Pancreas (31.5), Lung (22.2), and Peripheral blood mononuclear cells (6.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CDK11A Gene



NURSA nuclear receptor signaling pathways regulating expression of CDK11A Gene:

CDK11A

SOURCE GeneReport for Unigene cluster for CDK11A Gene:

Hs.651228

mRNA Expression by UniProt/SwissProt for CDK11A Gene:

Q9UQ88-CD11A_HUMAN
Tissue specificity: Expressed ubiquitously. Some evidence of isoform-specific tissue distribution.
genes like me logo Genes that share expression patterns with CDK11A: view

Primer Products

No data available for mRNA differential expression in normal tissues and Protein tissue co-expression partners for CDK11A Gene

Orthologs for CDK11A Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CDK11A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CDK11B 34
  • 97.95 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 95 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 90 (a)
OneToMany
CDK11B 34
  • 85.77 (n)
cow
(Bos Taurus)
Mammalia CDC2L1 34 35
  • 87.43 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 87 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Cdk11b 34
  • 85 (n)
mouse
(Mus musculus)
Mammalia Cdk11b 34 16 35
  • 84.27 (n)
chicken
(Gallus gallus)
Aves CDC2L1 34 35
  • 76.77 (n)
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 91 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia cdk11b 34
  • 73.16 (n)
zebrafish
(Danio rerio)
Actinopterygii cdk11b 34 35
  • 80.67 (n)
fruit fly
(Drosophila melanogaster)
Insecta Pitslre 35
  • 40 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea B0495.2 35
  • 41 (a)
ManyToMany
ZC504.3 35
  • 36 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CTK1 35
  • 27 (a)
OneToMany
bread mold
(Neurospora crassa)
Ascomycetes NCU07880 34
  • 53.04 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes ppk23 34
  • 50.26 (n)
Species where no ortholog for CDK11A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CDK11A Gene

ENSEMBL:
Gene Tree for CDK11A (if available)
TreeFam:
Gene Tree for CDK11A (if available)

Paralogs for CDK11A Gene

Variants for CDK11A Gene

Sequence variations from dbSNP and Humsavar for CDK11A Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1059811 --
rs1059816 -- 1,703,905(+) ATGCA(A/G)CCCAC nc-transcript-variant, reference, synonymous-codon
rs1059822 -- 1,704,605(+) TCCAC(A/G)TAGTT nc-transcript-variant, reference, synonymous-codon
rs1059825 -- 1,704,961(+) CTCAG(A/C/G)GACGT nc-transcript-variant, reference, synonymous-codon
rs1059828 -- 1,707,458(+) TGGGC(A/C/G)ACAGG intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for CDK11A Gene

Variant ID Type Subtype PubMed ID
dgv2e199 CNV deletion 23128226
dgv2e214 CNV loss 21293372
dgv38n54 CNV gain 21841781
dgv39n54 CNV loss 21841781
dgv3e212 CNV loss 25503493
dgv3n67 CNV gain 20364138
dgv40n54 CNV loss 21841781
dgv41n54 CNV loss 21841781
dgv4e212 CNV gain 25503493
dgv5e212 CNV gain 25503493
dgv5n111 CNV deletion 26073780
dgv8n100 CNV loss 25217958
dgv9n100 CNV loss 25217958
esv1455500 CNV deletion 17803354
esv2668621 CNV deletion 23128226
esv2758913 CNV gain+loss 17122850
esv2760410 CNV gain+loss 21179565
esv2764265 CNV gain+loss 21179565
esv27786 CNV gain 19812545
esv3550788 CNV deletion 23714750
esv3567896 CNV gain 25503493
esv3575582 CNV gain 25503493
esv3577686 CNV loss 25503493
esv3585007 CNV loss 21293372
esv3585010 CNV loss 21293372
esv3585015 CNV gain 21293372
esv3585016 CNV loss 21293372
esv3585017 CNV loss 21293372
esv3891747 CNV loss 25118596
esv6106 CNV loss 19470904
esv988165 CNV deletion 20482838
nsv1003545 CNV gain+loss 25217958
nsv1011683 CNV gain 25217958
nsv10161 CNV gain+loss 18304495
nsv1118094 CNV deletion 24896259
nsv1152112 CNV duplication 26484159
nsv1160797 CNV duplication 26073780
nsv1160864 CNV duplication 26073780
nsv1160925 CNV deletion 26073780
nsv159838 CNV deletion 16902084
nsv160062 CNV deletion 16902084
nsv160158 CNV insertion 16902084
nsv160496 CNV deletion 16902084
nsv436343 CNV deletion 17901297
nsv436733 CNV insertion 17901297
nsv442858 CNV gain+loss 18776908
nsv482168 CNV gain 20164927
nsv482937 CNV loss 15286789
nsv509368 CNV insertion 20534489
nsv545026 CNV loss 21841781
nsv545027 CNV loss 21841781
nsv545030 CNV gain 21841781
nsv545031 CNV gain 21841781
nsv545032 CNV loss 21841781
nsv822475 CNV gain 20364138
nsv822586 CNV gain 20364138
nsv822697 CNV loss 20364138
nsv822809 CNV loss 20364138
nsv834091 CNV loss 17160897
nsv950516 CNV deletion 24416366
nsv955437 CNV deletion 24416366

Variation tolerance for CDK11A Gene

Residual Variation Intolerance Score: 89.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 16.16; 97.58% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CDK11A Gene

Human Gene Mutation Database (HGMD)
CDK11A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CDK11A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CDK11A Gene

Disorders for CDK11A Gene

MalaCards: The human disease database

(1) MalaCards diseases for CDK11A Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
neuroblastoma
  • neuroblastoma 1
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for CDK11A

Genetic Association Database (GAD)
CDK11A
Human Genome Epidemiology (HuGE) Navigator
CDK11A
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CDK11A
genes like me logo Genes that share disorders with CDK11A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CDK11A Gene

Publications for CDK11A Gene

  1. Duplication of a genomic region containing the Cdc2L1-2 and MMP21-22 genes on human chromosome 1p36.3 and their linkage to D1Z2. (PMID: 9750192) Gururajan R. … Kidd V.J. (Genome Res. 1998) 2 3 4 64
  2. Centrosome-related genes, genetic variation, and risk of breast cancer. (PMID: 20508983) Olson J.E. … Couch F.J. (Breast Cancer Res. Treat. 2011) 3 46 64
  3. Cyclin-dependent kinases: a family portrait. (PMID: 19884882) Malumbres M. … Wolgemuth D.J. (Nat. Cell Biol. 2009) 2 3 64
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 64
  5. CDK11 complexes promote pre-mRNA splicing. (PMID: 12501247) Hu D. … Kidd V.J. (J. Biol. Chem. 2003) 3 4 64

Products for CDK11A Gene

Sources for CDK11A Gene

Content
Loading form....