CDK10 Gene
protein-coding GIFtS: 60
GCID: GC16P089753
|
|
cyclin-dependent kinase 10(Previous name: cyclin-dependent kinase (CDC2-like) 10 )
| |
Aliases
for CDK10 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Cyclin-Dependent Kinase 101 2 | | EC 2.7.11.223 8 | | PISSLRE1 2 5 | | CDC2-Related Protein Kinase2 | | Cyclin-Dependent Kinase (CDC2-Like) 101 2 | | Cyclin-Dependent Kinase Related Protein2 | | Cell Division Protein Kinase 102 3 | | Serine/Threonine Protein Kinase PISSLRE2 | | Serine/Threonine-Protein Kinase PISSLRE2 3 | | EC 2.7.118 |
| External Ids: | HGNC: 17701 | Entrez Gene: 85582 | Ensembl: ENSG000001853247 | OMIM: 6034645 | UniProtKB: Q151313 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n407987 n407986 | |
Export aliases for CDK10 gene to outside databasesPrevious GC identifers: GC16P081075 GC16P090742 GC16P089455 GC16P089496 GC16P088280 GC16P075448
Summaries
for CDK10 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CDK10:
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamilymembers are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to beessential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and itsfunction is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been foundfor this gene. (provided by RefSeq, May 2009)
Gene Wiki entry for CDK10 (Cyclin-dependent kinase 10)
|
Genomic Views
for CDK10 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010542.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CDK10 gene promoter:
AML1a Olf-1 CUTL1 ITF-2 Arnt
Other transcription factors
Search SABiosciences Chromatin IP Primers for CDK10
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDK10 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q24 Ensembl cytogenetic band: 16q24.3 HGNC cytogenetic band: 16q24.3CDK10 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P089753: view genomic region
(about GC identifiers)
Start:
|
89,747,145 bp from pter |
End:
|
89,762,772 bp from pter |
Size:
|
15,628 bases |
Orientation:
|
plus strand |
ORGUL member locations:
Legend (see complete legend)
89753075 89757924 89762772 chr16
|
Proteins
for CDK10 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CDK10_HUMAN, Q15131 (See
protein sequence)Recommended Name: Cyclin-dependent kinase 10 Size: 360 amino acids; 41038 Da
Secondary accessions: A8MXU6 B7Z420 D3DX82 D3DX83 Q0VGZ7 Q15130 Q6PJC0Alternative splicing: 4 isoforms: Q15131-1 Q15131-2 Q15131-3 Q15131-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CDK10: NX_Q15131
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15131
4/9 DME Specific Peptides for CDK10 (Q15131) (see all 9)
CDK10 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001092003.2 NP_001153839.1 NP_443713.2 NP_443714.3
ENSEMBL proteins: ENSP00000329957 ENSP00000338673 ENSP00000423370 ENSP00000424415 ENSP00000426102 ENSP00000421597 ENSP00000426264 ENSP00000455976 ENSP00000457055 ENSP00000456788
Human Recombinant Protein Products:
CDK10 Antibody Products:
Assay Products for CDK10: |
Protein
Domains /
Families
for CDK10 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CDK10 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q15131ProtoNet protein and cluster: Q15131 UniProtKB/Swiss-Prot: CDK10_HUMAN, Q15131Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamilySimilarity: Contains 1 protein kinase domain |
Function
for CDK10 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CDK10_HUMAN, Q15131Catalytic activity: ATP + a protein = ADP + a phosphoprotein Genatlas biochemistry entry for CDK10:cyclin dependent kinase (CDC2-like) related protein kinase,with several isoforms resulting from complex splicing,actingin G2 phase of the cell cycle,not deleted in sporadic breast carcinoma
Enzyme Numbers (IUBMB): EC 2.7.11.221 2 EC 2.7.112
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDK10 (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDK10 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 4): CDK10 (NM_052988) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDK10 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDK10 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK10 |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
CDK10 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for CDK10:
|
Pathways & Interactions
for CDK10 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell Cycle Control of Chromosomal Replication | | | 2 | GADD45 Pathway | |
2 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CDK10
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CDK10
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/8 Interacting proteins for CDK10 (Q151311, 3 ENSP000003386734) via UniProtKB, MINT, STRING, and/or I2D (see all 8)About this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007089 | traversing start control point of mitotic cell cycle |
TAS | 8208557 | | GO:0008285 | negative regulation of cell proliferation |
TAS | 8208557 |
CDK10 for ontologies About GeneDecksing
|
Drugs & Compounds
for CDK10 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CDK10
2 HMDB Compounds for CDK10 About this table
Search CenterWatch for drugs/clinical trials and news about CDK10
|
Transcripts
for CDK10 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CDK10 gene (5 alternative transcripts): NM_001098533.2 NM_001160367.1 NM_052987.3 NM_052988.4 NM_003674.2 Unigene Cluster for CDK10: Cyclin-dependent kinase 10 Hs.699177 [show with all ESTs]Unigene Representative Sequence: AK13153118/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20): ENST00000331006 ENST00000353379(uc002foa.2 uc002fod.3 uc002foe.3 uc002fof.3 uc010cio.3 uc002fog.4 uc002foh.4 uc002foi.3)
ENST00000508723 ENST00000505473 ENST00000511415 ENST00000502547 ENST00000512912
ENST00000505733 ENST00000510811 ENST00000507205 ENST00000472018(uc010cip.2 uc010vpl.1)
ENST00000564192(uc002fob.2) ENST00000378277 ENST00000514965 ENST00000503560
ENST00000504473 ENST00000568456 ENST00000561477
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDK10 (see all 9)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDK10 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): CDK10 (NM_052988) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CDK10 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDK10 |
Additional cDNA sequence: AK131531.1 AK290485.1 AK292351.1 AK295397.1 AK296631.1 AK298386.1 AK312016.1 BC017342.2 BC025301.1 L33264.1 NR_027702.1 NR_027703.1 24/29 DOTS entries (see all 29): DT.92413136 DT.120667672 DT.97847205 DT.100837924 DT.97847207 DT.100816583 DT.86854973 DT.95252922 DT.120667665 DT.100816578 DT.95252931 DT.99958417 DT.100816587 DT.100836930 DT.95306968 DT.100816593 DT.101984825 DT.95252941 DT.120667608 DT.120667648 DT.86854975 DT.102830992 DT.120667647 DT.120667667 24/255 AceView cDNA sequences (see all 255): AI624128 BX370771 NM_003674 CR615113 AA150212 BM773127 BQ889462 BM781649 CR617735 BM142087 BI826027 BM720563 CR612010 NM_052987 CK819887 BI771697 CR624710 CR599641 AK075036 BI823967 BQ214789 NM_052988 BG676853 BM452234
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for CDK10 (see all 18) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | · | 10c | · | 10d | ^ | 11a | · | 11b | · |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | - | | - | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | - | | - | | - | | | | | | | | | | | | - | | | | - | | | | | | - | | - | | - | | - | | | | |
| SP3: | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | - | | - | | - | | - | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | - | | - | | - | | - | | | | |
| SP5: | | | | | | | | | | | - | | - | | - | | | | | | - | | | | | | | | | | | | - | | | | - | | | | | | - | | - | | - | | - | | | |
| ExUns: | 11c | · | 11d | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | · | 15c | · | 15d | · | 15e |
|---|
|
| SP1: | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | |
| SP2: | | | - | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CDK10
|
Expression
for CDK10 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CDK10 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGACCCAA
About this image
See CDK10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CDK10
SOURCE GeneReport for Unigene cluster: Hs.699177
SABiosciences Custom PCR Arrays for CDK10
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDK10
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CDK10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDK10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDK10 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK10 |
Orthologs
for CDK10 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CDK10 gene from 5/26 species (see all 26) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CDK101 |
cyclin-dependent kinase 10 |
79.57(n)
84.96(a) |
|
415840 NM_001109939.1 NP_001103409.1 |
lizard
(Anolis carolinensis) |
Reptilia |
CDK106 |
-- |
72(a) |
1 ↔ 1 |
GL343487.1(618254-631732) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.127572 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.57(n) |
|
BJ071284.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.168352 |
Transcribed sequence with moderate similarity to protein more |
76.67(n) |
|
BI983627.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
cdc2rk1 , 3 |
protein amino acid phosphorylation protein
serine/threonine more3
cdc2-related-kinase1 |
66(a)
(best of 2)3
64.92(n)1
66.46(a)1 |
|
46E13
360511 NM_078950.31 NP_523674.11 |
ENSEMBL Gene Tree for CDK10 (if available)
TreeFam Gene Tree for CDK10 (if available) |
Paralogs
for CDK10 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CDK10 gene
- CDK11A2 CDK11B2
18/120 SIMAP similar genes for CDK10 using alignment to 10 protein entries: CDK10_HUMAN (see all proteins)
(see all similar genes):EIF3G pp12301 ADCK1 PPP5D1 ARIH1 NDC80
NELFA PFKFB3 C12orf76 IRF2 FLJ00047 RRM2B
EEF1E1 HINFP NCKAP1L NLRC5 SLC35E3 TBCB
CDK10 for paralogs About GeneDecksing
|
Genomic Variants
for CDK10 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CDK10 (89747145 - 89762772 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CDK10
2 CNVs: 49803 4977 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for CDK10 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CDK10 for disorders About GeneDecksing
OMIM gene information: 603464
OMIM disorders: --
6  diseases for CDK10: About MalaCardsseminoma ovarian cancer breast carcinoma breast cancer
melanoma carcinoma
Export disorders for CDK10 gene to outside databases
|
Publications
for CDK10 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CDK10 gene, integrated from 9 sources (see all 37):
(articles sorted by number of sources associating them with CDK10) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- PISSLRE, a human novel CDC2-related protein kinase. (PubMed id 8208557)1, 2, 3 Grana X.... Giordano A. (1994)
- Molecular cloning of PISSLRE, a novel putative member of the cdk family of protein serine/threonine kinases. (PubMed id 8084611)1, 2, 3 Brambilla R. and Draetta G. (1994)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The PISSLRE gene: structure, exon skipping, and exclusion as tumor suppressor in breast cancer. (PubMed id 10036189)1, 2 Crawford J.... Savoia A. (1999)
- Cdk10, a Cdc2-related kinase, associates with the Ets2 transcription factor and modulates its transactivation activity. (PubMed id 11313931)1, 9 Kasten M. and Giordano A. (2001)
- Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer. (PubMed id 7882308)1, 9 Bullrich F....Croce C.M. (1995)
- Human CDK10 gene isoforms. (PubMed id 11006117)1, 9 Sergere J.C.... Leteurtre F. (2000)
- Effects of partner proteins on BCA2 RING ligase activi ty. (PubMed id 22315970)1 Bacopulos S....Seth A.K. (2012)
- CDK10 functions as a tumor suppressor gene and regulat es survivability of biliary tract cancer cells. (PubMed id 22209942)1 Yu J.H....Cui Y.F. (2012)
- The global gene-expression profiles of U-937 human mac rophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)1 Lin C.W....Jan M.S. (2012)
|
External Searches for CDK10 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CDK10 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CDK10 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CDK10 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for CDK10 gene:
Search GeneIP for patents involving CDK10
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CDK10 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for CDK10 | | OriGene shRNA RFP for CDK10 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CDK10 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CDK10 | | | OriGene Protein Over-expression Lysate for CDK10 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CDK10 | | OriGene 3'-UTR Clone for CDK10 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CDK10 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CDK10 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CDK10 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CDK10 | | OriGene Custom Protein Services for CDK10 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CDK10 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CDK10 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CDK10 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CDK10 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CDK10 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CDK10 |
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| | | | Search Tocris compounds for CDK10 |
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 | | | CDK10 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CDK10 |
|  |  |  | | | | ThermoFisher Antibodies for CDK10 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CDK10 |
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Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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